Document 2NjVb7Lv8YYJDvY72dwxJvMb

^ohmond^olimon CONSUMER SKILLMAN, NJ 06S58-94J8 January 20, 1994 SUBJECT: J&J. CONDUCTED/SPONSORED SAFETY STUDIES ON TALC TO: W.H. Ashton Bill, I have just gone through the TALC ARCHIVE FILES in Skillman South and list below the safety-related studies initiated by J&J, tied to dates: 1./ nr**' Quantitative and mineralogical analysis of Johnson's Baby Powder and SHOWER TO SHOWER* POWDER: McCrone Laboratories - 1971 and 1972 Colorado School of Mines Research Institute - 1971 F. D. Pooley - 1971 G. E. Brown - 1972 2. X-ray Diffraction & Differential Thermal Analysis of JBP for yvj Chrysotile Asbestos - Rolle & Schelz - 1972 3. Characterization of Talc & Associated Minerals - Rolle -1976 ** j 4 . '1' Extraction of Trace Metals From JBP - J.A. Molnar - 1976 5. Histological Response to Intradermal Injections of Talc, Tremolite & Chrysotile - A.M. Kligman - 1971 eV r Animal studies with Italian Talc, 1970 - 71 Twenty-day Repeated Application Study Sensitization Study Photosensitivity Study Acute Biological Studies Chronic Biological Studies 7. J Subcutaneous and Intramuscular Administration of Talc to Mice - Consultox Laboratory - 1972 Epidemiological Study of Miners (Windsor Minerals Mine, Vermont) - G. Green - U. of Vermont - 1974 Evaluation of Effect on Pulmonary Function : Time & amount of dusting in babies - S. Sawchuk - 1972 Particle count of respirable & non-respirable particles in simulated dusting - F.D. Pooley - 1972 10. J&J Employee Talc Exposure - medical & environmental records C.B. Myers - 1972 ^ ^ (A- J Protected Document-Subject to Protective Order JNJAZ55_000003191 Page 2 11.^ Talc Safety - A Literature Review - J&J - 1973 Jjj. ^ 12 .^v/Estimation of Talc Dust Exposure for Infants - A. Eden -1974 13.^ Baby Inhalation Report - J. Sivertson - 1974 1 4 ^ ^ JBP Residual Deposition in Baby's Liang - F.R. Rolle - 1974 15.y Biological Testing of Talc in Rabbits, Rats and Hamsters J&J Research Foundation - 1974 / V "t Pulmonary Deposition, Translocation & Clearance of Inhaled '-'ft k Neutron Activated Talc In Syrian Golden Hamsters - ^ ^ . Battelle Pacific Northwest Laboratory - 1974-76 17^^ Mortality Study of Talc Workers - G.V. Rubino - 1974 lS.v^Tissue Culture Study of JBP - J&J Research Foundation - 1976 19. ^ S a f e t y Factors for Battelle Studies Based on Dusting Experiments Using Live Infants - J. Rafter - 19J6^ 20. P^The Determination of Respirable Particles in Talcum Powder v and Ac*ult Powdering Peak Respirable Concentration - R. Russell - 1977 / . 21. The Biology of Talc - G.Y. Hildick-Smith - 1976 _________ Macrophage Stn<^ ______ _______ 23. y Biological Effects of Talc On The Experimental Animal .A,As ,G.H. Lord - 1977 24. On Talc Translocation From The Vagina To The Oviducts And Beyond - Battelle Pacific Northwest Laboratory - 1986 \ C . Seaman CIS Protected Document-Subject to Protective Order JNJAZ55 000003192