Document 2Lbx1VjygpermNqvO16wO8R

08/06/2003 WED 09:43 FAX 312 996 1899 UIC LBS CHICAGO @005 MESOTHELIOMA--L1EBEN & PISTAWKA from 1925 to 1938, and later in a plastic fabri cation plant which utilized fiber glass; he also had been a welder for 25 yean. He thinks he has used asbestos but could not recall when and where. Patient 10-Q, a 63-year-old man, was a core-maker all his life. He worked in two foun dries in one of which asbestos cement is used in small quantities but, according to the plant manager, the core-maker did not have any con tact with this material. The son stated that his father had used asbestos pipe insulation for pipes in the basement of their home several years prior to the onset of his illness and that he had done some sawing of this pipe insula tion material, All cases in this group had pleural mesothe liomas. Mesothelioma Patients Without Asbestos Exposure.--In the other 11 patients (1-X to 11X) no occupational, familial or neighborhood asbestos exposure evidence could be elicited. Ten of these patients had mesothelioma of the pleura and one peritoneal mesothelioma. Comment This study presents a good deal of circum stantial evidence and many unanswered questions. Asbestos is a ubiquitous material used much more frequently than is generally real ized. Some uses, such as in the brewery, were not previously known to the writers. There are undoubtedly many others. If we assume that asbestos may be the causative or trigger agent for malignant mesothelioma in some of the cases described above, we must admit that the minimal dose-effect relationship and duration of a latent period are unknown. The occupation al exposure of the insulation workers or as bestos textile workers were certainly many thousand times higher than those of the neighborhood cases or family contacts. Simi lar findings have recently been reported from England.1 The attack rate for mesotheliomas is ex- Clergymon Patient 2-N tremel portec doubli of tb There diseas patter tacts, attack tween Ant pleurt frequt Tht was t came matel; and i These ing t neigh N) ai daugl Fo: ed fr od, v asbes were asbes work work patie work sumt after Nurse Patient 2-F Occupational, neighborhood, and family contact patients with mesothelioma associated with one insulation plant. Arch Environ Health--Vol 14, April 1967