Document 2KmaDRDK4Yn1roxBadXbpJ07

March 3, 1986 H. W. Dietz Subject: Toxicology Activity Report - February, 1986 sted the FPD in preparing a preliminary information package for submittal to EPA. Following this activity we met with EPA to determine the requirements for pesticide registration of four Promac products. The FPD has askecLthat every effort be made to expedite testing. As a resultMPfiaSje requested the necessary protocols which will be hand delivered to tamext week at the SOT annual meeting. 2. I have been working with theJ^MA-HubbeY AOOTtlves Panel in developing comments onthe_ju^posd^testrul e for MBT. These comments were subfoit*ed'"to TPAon February 28. 3. We have been notified that EPA is preparing a CHIP (Chemical Hazard Information Profile) pn^Cure-rite 18. With the assistance of the SP&C business group^Hiavp assembled a detailed package covering physical chemical properties, workplace and consumer exposure, environmental fate, and human and environmental effects. This Is a very Important project because of the attention rubber chemicals are receiving by EPA (l.e. test rules). Fortuitously, we have developed a considerable amount of data. In the future Jlrplan# to review information deficiencies with the product group. Hopefully if we can complete the development of a minimal database, we will be able to avoid an expensive test rule on CR-18. 4. The Estane business group is continuing to pursue potable water pipe clearances through a joint project with Shell and Insitu Form. Earlier this month we met with representatives of Shell and the N.Y. State Dept, of Health andfaffevvewed the limited toxicological data on Estane polyethers with them. No estimate was given as to when we might have a response. However, Shell is taking the lead role and will keep us informed. 5. I continue to be involvedjtifc-ttiSH,app1on lung cancer case and am now completing m^jcevteWof the background information. My deposition and the tria+'itscheduled for March. 6. The New Products Group is worjp-mf"Kith Velsicol in evaluating some chemicals as plant growtM'tfgulators. I have provided guidance regarding TOSCA an^ffF^A test requirements. 7. ^/"melTwi th the SP&C Group to assist them in prioritizing research to find alternatives to benzene as a solvent for Carbopol. Additional toxicity information review was requested on several solvents. BFG23145 I006T6SS 8. OSHA has begun preliminary maneuverlng^ie-'TSgulate BD. I am working with IISRP in preparing commerjis-:--He believe that the present ACGIH TLV of 10 ppm is adequa^e-efitfthat OSHA does not have any scientific basis to set a st^wtarFd of 1 ppm. The VI Technical Committee met this montiuaffiT 1 provided an update on the baboon and rodent studies on Hp-r^-fill work Is proceeding satisfactorily. The med1cal/oxfcological subcommittee has also been asked to review the hasfs for the EPA dioxin risk assessment; an FOI request has been s^ttrntted to EPA. .^^ave^repared a draft submission for compliance with the TOSCA 8d 10 health and safety reporting rule for vinyl acetate. This draft has been submitted to the Geon Company for their review. R. K. Hlnderer JP BFG23146 22913002