Document 2Jxw52QvY6m03Qv4DjxvwMnb7

To: jarnotb@api.org <jarnotb@api.org>; benzene-erp@listserve.api.org <benzene- erp@listserve.api.org>; benzene-srp@listserve.api.org <benzene-srp@listserve.api.org> From: rlarson@medicine.bsd.uchicago.edu <rlarson@medicine.bsd.uchicago.edu> Cc: Jmricewas@AOL.COM <Jmricewas@AOL.COM>; rlarson@medicine.bsd.uchicago.edu <rlarson@medicine.bsd.uchicago.edu> Bcc: Received Date: 2003-09-0921 :18:07 GMT Subject: RE: Shanghai SRP & ERP... for review... draft Asilomar minutes Bruce, Thank you for the minutes of the Asilomar meeting. I would only add to page 4 under "Suggestions for further and/or expanded future studies" the proposal that a mechanism be developed for other investigators to apply for access to the leukemia tissue bank that is being developed by Dr. Irons in this study. The National Cancer Institute Clinical Cooperative Groups have developed and published criteria for reviewing concepts or research proposals from other laboratory investigators for access to their tissue banks. (See: Schilsky RL, Dressler LM, Bucci 0, Monovich L, Jewell S, Suster S, Caligiuri MA, Kantoff PW, Compton C. Cooperative group tissue banks as research resources: the Cancer and Leukemia Group B tissue repositories. Clin Cancer Res. 2002 May; 8(5): 943-8.) These clinically and biologically very well characterized cell samples are an invaluable resource. Such a review panel should include a biostatistician, and molecular biologist, and a clinical leukemia specialist or hematopathologist in addition to the principal investigators. Given the rapid development of gene arrays, there could be much to gain by collaborating with one or more of the bioinformatics groups doing gene array studies in leukemia. Such experiments could especially contribute to the second specific aim of the Disease Progression Study to "characterize... the earliest molecular lesions involved." Thank you. Richard Richard A. Larson, M.D. Professor of Medicine The University of Chicago 5841 S. Maryland Avenue, MC-2115 Chicago IL 60637-1470 Phone: 773-702-6783 Fax: 773-702-3002 E-mail: rlarson@medicine.bsd.uchicago.edu -----Original Message----From: Bruce Jarnot [mailto:jarnotb@api.org] Sent: Wednesday, September 03,20039:21 AM To: benzene-erp@listserve.api.org; benzene-srp@listserve.api.org Cc: Jmricewas@AOL.COM Subject: Shanghai SRP & ERP... for review... draft Asilomar minutes TO: Shanghai Health Study - Scientific & Ethics Review Panels (SRP & ERP) RE: Draft Annual SRP/ERP Meeting Minutes for Review DUE: by Wednesday, 17 September 2003 (2 week turnaround) ***** Dear Panel Members - Please review the attached draft minutes from our recent annual meeting in Asilomar, and provide comments or recommended edits to me by reply email, with copy to Jerry Rice, by September 17th. SH ELL-MCCLU RG-064698 Note to Drs Albertini & Greim: please take this opportunity to expand or refine the section on "bioexposure endpoints used in other studies", page 4. Thanks to all for your kind attention! Best Regards - Bruce. ***** Bruce M. Jarnot, Ph.D., DABT American Petroleum Institute Regulatory and Scientific Affairs 1220 L Street, NW (Suite 900) Washington, DC 20005-4070 phone: (202) 682-8473 fax: -8031 email: jarnotb@api.org SH ELL-MCCLU RG-064699