Document 2Jve0n5kxJwkZqd6XNDK62LyR

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nterottice corressonvence S00 ---- Magust 20, 1-- 975 August 20, 1975 S~UuBIbEjeCtc:t. F3F1ll0uu0oodrrooccFaalrrabsbonoannss in in HHuummaann Blood P] asma cCOoNnFiIpDeEnNrTiIaALL ~[ rToO:: SNELJ53...05CACD.... uLKTKRAAROOZZmGGEEHHRRTTnEE-- C-C-OOMMCCGMMOOoEEMMRRMMvIEIECRRCtACCALIILAARLLCCHHeCEECMHMsHIIEECCMaMAAIILLCCAALLDDII2DVDV0IIII1VSSV-ITII2SOOSINNIOONN-- 2=2223323--666-SS1EE - 236-1 tw .AA.. NPPEEEWNNMDDAEERRRGKGRRAA-SSSSCEN--TRMMAEELDDIICCRAAELLSEADDREECPPHAARRTT-MMEE2NN0TT1-2--W222200--22EE FPRROOMN:: GG.. HHl.. CCRRAAWW~FFOORRDD -- PPHHOOTTOOGGRRAAPPHHIICC PPRROODDUUCCTTSS -- 220099--11S5 Record of a Telephone conversation - August 13, 1975 Record of a Telephone Conversation - August 14, 1975 :i PPeerrssoonn ccaalllliinngg - DCUDCrroon..llillveeeWWggriieesllilltiiooyafafmmMMofeGGeduudiyysFcciiionni~:da i GGUaaniiinnveeessrvvsiiilltllyee,,ofFFllFoolrroiirddiaada i i DeDeprraoa..rsrlslGiGiieuuberyylremcmceoaasmmllooollu))eerddcettsoaoaggaasosiifeonneo,,thiiffeffoowwllfeellloouwwhhoaiairddnnoggcaaarnumuypypbonooffnnuucrrattttrhhhheeeberorxssyuuiil,s0i]ijjeecaeeasccsttacaasis((dvvsttiiooddeefommuyynd | JpiTononhsnshhiuubmmPalaenenndebbsrllogoouroordacdsessssaaommonfpplleettsshhee ffrfrLooilmmnueoTTreeoaxxncadaassrGbuoaanynnddbcrNaNoerewtwbgohxYTtyoo~[rkkii..cn aacI1ibdegg.soottTfaoyusnd | J((owwhhhnoo aPapeppnpadarererengntrtlalysyswwaaossn tiihnnevvoolllvvieended aiinnnd tthGheeuyoorbririggoiiunngaahllt ooibbnsseearrvvDaar.ttiiooTnna))y..s | TNTheheew oYoorrriikgg,iinnaaRllochsseaasmmtppellrii,nnggNeiiwnnvvooYllovvreekdd (ppLlloaawssmmnaaatussrppeaeclciimmf.sl]nnussoriffdrreoommiAnAllbbtaahnneyy,, wwNTaaeettxweearrsY))or(kHHh,iiillgllhRssobbcnooharretoosuuutrggeahrhl,,, fTNTleeeuxxwoaarssiY,,doer)AAk.nndd(rrleeTowwhwsse,,rneaTTteweuxxaraagassl,,fofa.lanmundeodarsiCCudooerrrappbuuislsneCCthhhrreiissttii,, Tdbdb"yeiyhixaffatfPbesrerroorteffeh(n..nehccieeWWfgaahlllbbullyynoaaarcctirreeuneereggaiiBBloorrinnsoeyyfol((ru11((go00bDra-e-ein6pp6dtti..ecmm)oo.llooaaffanrrdCCThhtFhFe-ehe))mrem...e,,swuaFUFUs..s11p39ecnooftfNoNIeA4dmFRFR..e))assSstptuueuiirdcdnnaiiiddbeeeiissslcceaattrrieeusunn DtDhffrrhllu..auutoeoBBrryrrooteehcc:eyyaarrbbfssooulunnsuspoperecccicaatntrrsesbbooxxaaiyysllbbiirroccaarnn@ccaaahhncceeiiiddcdd ewwaininttddhhtonhaaeCCt6ghseusoorrcpheaCCci77tne,dfflleusu.opogrer.ocoaialelpksheyyrfllilsuggorrrooouu.pp.. end on the chain, e.g. perfluoro t-butyl. TTthhoeewdhdieisrscecuusssssuiicoohnnaiinn"vvuoonllivvveeeddrsaDDrlr.. GpGuuryya''sssencsseppeecocufullaasttuiicwvh~ecoqqmuupeeossuttniidoosnn.ssinaass i{ hHtinouo"mnawalnhnaebrbboellrooaootsddourcyhccoouuaallnddi"muaccnlooimsmve.ee.)rsffarroloTm"mh.."espere((siTTenhhneeccleuccdooemmodfpp:oouusnnuddcssh acarroeem.ponnuoonttdspprreeissneenntt in laboratory animals.) These included: | i1.. BBiioossyynntthheessiiss ffrroomm iinnoorrggaanniicc F=-.. i 22.. cBBhiilooossryyinnnttehh)ee:ssiiss ffrroomm aaeerroossooll ffrreeoonnss ((bbuutt tthh,u~yy ddoonn''tt ffiinndd {i chlorine). Ex1h1i1b8it MSMuaabddjseecAAtvvaaiilPaarbbollleecbbiyyiv33eMWOfrfoodrerIInnIssnppeePccattmiioeonnrvaa.nnddGCCMooppNyyoii.nnggC2aa-ss0CC4o.on6nf3ifid0de8ennttiiaall formation Information: Subject to Protective Order In Palmer v. 3M, No, C2-04-6309 1111188..00000011 MATO034562 3MA10034962 TTAfe~ealg]ueeaspplthhooinn2ee0, CCootnnivvseerrssaattiioonn 1975 -- DDrr.. wWii]ll] i~aamm GGuuyy ~ ag~ -2- 3. Tetion cookware. 43.. T"eSfclootnchgcaorodkewda"re.fabrics. CcS$S41.aaoo"rrmmbbeeCoowwh"xxahhSyyyeecllrro]ieewtccecrhhheeegaaaccrigpigddarooessattds"oaattnrrhhteeeefauubiiinrssnnieeffcddo"osrrS.mmaacgsaa.otttiiSseoouuhnnrrsffaaattrcchhdaiatttaannortt3WseM'o'stsaahnndde~frllwwuuaaootmnrretcooreeccsddaarrbbritooononnkskennvooewwral uuFissfSeecotbtbhyytenygttewhhreeedrteppuuwbpblarliseicsc.eantpWWoeeliynmppell"reeSaiacdcdotcmishegggtnuaeoorrrrdtaa"ennscceeormebbruuottthaesardtvvieiissteeeddmaschheiii"mmn hat general that ; AOBAo"FferpSpepcagTaFo=-rurtenecnanhiitbtgnnllalyyryhhduu"ammaanananntnweaeedsppaaallrrtaallaesisimemeparartohley((((mnn'1eooi55trt99ni--c'c1nrn66eee00acmc))seaeestsdsesssarattriruwuiiadhdlllyeyyyonttfFFouuCEtrrnneieeddatddeehrrFeii.uruvvC.ppe.eddssb))iiai;;mmcoiiirdlltte.aahhhrriigssaqqnwuwusoaao:unnulttddiittiieess presTuhmearbiloyn anGtooerduaatree:the increased use of either "Scotchgard" J! TTCohrhoeeoyyt"wTahhezafaevlveoenw"ddiootnnhceeoonkeeewgxxaapprteeeirr.viiemmeennrttesssuliitnnsvv:oollvviinngg wwaatteerr bbooiilleedd iinn TTeefflloonn :| WWaece.eo;goi.kssswuucNagNgoreeggtewweecssnttwGGeeuiugddiitannhreeooaaabbn:tteaawugniihaeenntrriiieennv.gge ttphhpreleleyyasasuslmmddotaaonsn'.'sstt.ppeecucusiibemmeeenntsso6o0 ffmmrruaooccmnhh uunn""ccTTiieevvffliilolloniin"zzeeddccooaaomrrkeeewaaarssrs,,e OTOorFffPreeEssiaia"ldldiSlluuncaaollTtttechhefehFFgclCaouurnnn11d4ll4"3c3ii.okkoee((klloowyyfrarwweeehhxx.aappttlleeaavvnTneehaarritt))siioonwwn1esess aasssbbeteoorilvv]lleel,,ttpoottrhheeoDDvuUePLlPsoueRnaaEtssfttasttoououtnnblppleioioekklrheeyyollmmsyyem:riiiizzssee This TFE This was not in Teflon was not (1 hasten cookware. (I hasten to sap) This to say) supsestes tor. ay is still pretty far-fetched. suggested to ]]r. Guy. WaWSaeesanseaiailaosdydnttooippcttiiaeennlddaannapayyeoppwpowoalsasyeyiittiipPhooaoonndssnsstioiobfbfllbeeessccaaiiannbeedldnnettiissffutuiieggccggeecssclcttauueerrrddiiitooysstthiihetatb.:y.s. oaoanvunbdedrredodowwoee'nnssiirrneeurttoo rafEelinnsnaapdlleiyncntgtgiaesc.da,l((1IcpoekknonnsopoewwlrevWWaaamtlliillgvaahect.ceeabenBBdrraeeyybolteffrrgotoiomnvewacnalyyartiobbfaacgyfkkr..iD:v$o.lHHoeeBurs'eiiysb'sshhpiiegNcghMullRryyations) NaMArAeccfefbBqtstrerpueeraraacddityywnweeetdeaa,dnnhhdduuwnnciggRoRtinihcscuuhpehparaBrvrrI1dadetycciNaNaveeallewwnllmmdeeaaddarrnhkkdCCa..HRtLLnoAtAITIntonnaagllittfyyvuaittcreeiiennncscseaatllooop,,uuuttbflrttiiaats~c_hh,hkaekoeetseldddoNNuestatewoorwmsaJaJpeoroeyhkhWcnnukliiasstions). Sournal edited by Brey: acquainted with Brey and journal edited by Brey. has, in fact, published in a NMR MpMpKiiyyneneeerrphhrSrtaaooeeppuuccSssccooehnmmimomsswweneaaiintmnmttidpdpohhalalrettessiisBBorroeennttSyoyoa',.l((krrwwioouuiinnbbnttgtthhaaooiiJnnJtnn.o.pPoou..usssr'r'ppe.sseeicCceeetqnccArrutooNaiainnIpcscPmueuffersrRoonrrrrRteeiC,nnhhhcciieesseet))ttheceoO..w::h.nsss piLhintti(eoonnioottttggeethoerrhettpoerrfrreoRRtwtwiioaaoccrtrrhhddiiaaseoorr,nnndd Cooporative seioncitie"ingutnr: keep scientists talking to scientists cooperative scientific inquiry. in the spirit of OOttTtSnnhhhohaameetteiittrrhhemeeeebvDvdleLpBiorooEpoooyspysadbibtilsotoattdidtirvyyyPvee"eoeaasi1mnss3ssssiiibgdddwwieoeoiiliititnn--hthggiiienfafansoorrooiiauautttpnpnhodpdaiisatssewrweweiiccnontcootuthhnn.lffdiifi1frr1lllml1mbuo-eoeeooecddartftrooficctteoaaooc<rtr.obbtokousoouiur,nnrrng.sassssoruaaeenrttrifiifnatssapehcffchsetaateraccanenttnWtiitesoosnn iinn some medical possibilities that would bear l<oking into? We W|ade Avatabl by Mfr Inspecion and Copying as Confident information Made Available by 3M for Inspection and Copying as Confidential Information: `SSuubbjjeecctt ttoo PPrrootteeccttiivvee OOrrddeerr IInn PPaallmmeerr vv.. 33MM,, NNoo., 2C-20-044--66330099 11111188..00000022 awAto0a4ses 3MA10034963 suinaone Goneennion = os viktitem ug Telephone Conversation - Dr. William Guy Soasanens cone August 20, 1975 Hs Page -3-- know that fluorocarbons are good oxygen carriers (but this is prising oni oR oul straight FC-75, not dissolved FC 143). Can fluorocarbon pr EE RI RE surfactants improve the hemodynamics, wettinj and capillary Erinn gBe o Ee permeation of blood in cases of atherosclerosis, kidney blockage, Bermption oF hovd in cases oF Finproacierosiy. kidhey bie senility and the like? Can hemolysis, plate[et destruction senilityand doLied Son gemeizaie: platelet destruction and other blood damage during hemodialysis and cardiovascular Te Io Simin ilairtls wd cardio] surgical procedures be reduced by fluorocarbon surfactants? gurgicel proseduier be ote ed, ur Sisormcarion surectantst This is speculation (but not completely wild}. I would like Bo ly TT iri to suggest that we consider some animal expeciments to see oe Sho vf coslies oe nina pperiepnes to ue, just how much of these materials can, in fact, be tolerated Jao,opmh of tes materials can, infact, be tolerates, in the bloodstream - both from a defensive point of view and inthe Slocdstrem beth from derensive pine ot view at for the above (to me) intriguing reasons. Wlat do you think, Sort John? are i J GHC/Ir ' Wade vaoySoirrapl acton snd CopasyCionntga formation Made Available by 3M for Inspection and Copying as Confidential Information: `SSuubbjjeecctt ttoo PPrrootteeccttiivvee OOrrddeerr IInn PPaallmmeerr vv.. 33MM,, NNoo., 2C-20-044--66330099 11111188..00000033 -- 3MA10034964