Document 2Jjd3QKDm2n68Oo16bpqBYa36
To: BenzConsort-OC@listserve.api.org <BenzConsort-OC@listserve.api.org>;
BenzConsort-TC@listserve.api.org <BenzConsort-TC@listserve.api.org>
From:
Russell White <whiter@api.org>
Cc: Howard Feldman <Feldman@api.org>; John Wagner <Wagner@api.org>; Robin
Tillery <tilleryr@api.org>
Bcc:
Received Date:
2006-11-17 14:32: 18 GMT
Subject:
Shanghai Health Study - REMINDER - Conference call November 17, 1:30 PM EST
Attached are two items for your review before the call; the minutes from the last call from Jennifer and a budget spreadsheet to help guide discussion of Dr. Irons' new proposal. Please note, we do not yet have estimates from Dr. Wong, Fudan University, and other contractors at this time. Included in the spreadsheets are Dr. Irons' proposed budgets and my unofficial estimates of other contracts.
Draft agenda;
1) Establish quorum and note taker - Patsy 2) Review antitrust guidelines - Mark 3) Dr. Irons' grant requests - Jennifer 4) Other contracts - Russ 5) Planning for the meeting in December - Patsy/ZachlTrisha
Meeting times - Agenda items - Dinner 6) Other business/next call - Patsy
Conference call: Toll Free Dial-In Number: (866) 443-0059 International Dial-In: (770) 765-9147 Enter this code at the prompt: 202 682 8344#
Operator-Assisted Service: Toll-Free Dial-In Number: (800) 572-9844 International Dial-In Number: (706) 643-1733 Call Participant Functions *0 Operator assistance
*6 Mute your own line
>>
Picture (Metafile)
Attachments:
DRAFT Spreadsheet for proposed JCML budget 11-13-06.xls Picture (Metafile) SHS Oversight Committee Call Nov 9 2006.doc
SH ELL-MCCLU RG-062778
Cost Centers
Inception
Project #
Thru
December 2004
Benzene Health Research Consortium
Executive Summary
3Q06 Financial Report
Original
Original
Actuals
Jan - Dec 2005
Projected
Jan - Dec 2006
Projected
Jan - Dec 2007
Original
2007 EOY projection
Income
$ 16,765,693 $ 5,206,657 $ 2,826,039 $ 1,535,748
26,401,122
Cost Centers UCHSC + JCML Irons-Field Expense Applied Health Sciences Fudan University
X8105 X8106 X8107 X8108
Scientific & Ethics Panels X8109
Communications
X8103
Outside Legal Counsel X8104
QAlQC Support
X8110
API Administrative
X8100
Exposure Assessment x8111
Contingency
10,137,850 788,486
1,391,014 124,090
181,713 294,161
64,529
856,208
104,473
3,624,030 262,000 548,720 4,007
76,176
33,706
170,475
51,918
4,000,000 262,000 547,953 94,472
92,549 1,946
31,244 16,667 163,500 40,000
570,889 100,942 502,311
80,704
13,778,460 990,282
96,726 1,946
31,242 16,667 225,450 69,000
18,332,769 1,413,428 2,989,998 303,273
447,165 298,053 160,721
33,333 1,415,633
109,000 156,391
Total Expenses Fund Balance
$ 13,942,525 $ 4,771,033 $ 5,250,331 $ 1,695,877
$ 2,823,169 $ 3,298,247 $ 873,955 $ 713,826
$ 25,659,765
FINISH 2007
Jan - Dec
7,299,004 548,000 95,000 95,000 33,000 175,000 69,000
"$ 8,314,004
All numbers
in yellow are
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Page 1 of 26
AUTO DATE
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FINISH
2008 Jan - Dec
TRANSITION
2007 Jan - Dec
Benzene Health Research Consortium Executive Summary
3Q06 Financial Report
TRANSITIO N
2008 Jan - Dec
Original
2007 EOY projection
FINISH
2008 EOY projection
POST TRANSITION STUDY
2008 EOY 2008-2009 projection
26,401,122
503,000 65,000 95,000 35,000
180,000
$ 878,000
8,539,004
548,000 95,000
95,000
33,000
175,000 170,000 69,000
503,000 65,000
95,000
35,000
180,000
$ 9,554,004
$ 878,000
18,332,769 1,413,428 2,989,998 303,273
25,060,884 1,312,486 3,538,687 382,569
26,300,884 1,312,486 3,538,687 382,569
600,000
447,165 298,053 160,721 33,333 1,415,633 109,000 156,391
540,439 296,107 197,479 16,667 1,545,183 109,000 156,391
540,439 296,107 197,479 16,667 1,545,183 109,000 156,391
$ 25,659,765
$
$ 33,155,892
$ (7,496,127)
$ 34,395,892 $ 600,000
$ (8,736,127)
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AUTODATE
t:xpenaltures :
Personnel:
lotal Personnel:
Operating Expenses
~~ ,~~ uHANI
Accumulative Actuals to date
06/30/06
Projected for 07/01/06 to 12131106
Projected for 01/112007 to 06/3012007
Projected totals 07/0112007
Projected for 07/0112007 to
1213112007
Personnel at UCHSC: $
Personnel at JCML $ Other: $
$
2,402,457 $
-$
3,900 $
2,406,357 $
245,804 $
-$ -$
245,804 $
235,083
664,320
-
899,403 $
$ $
3,551,564 $
246,837 664,320
911,157
Expendable Supplies: $
Non-capital Equipment: $
Services $ Maintenance: $ ME feasibility
Study: $ Contingency: $
1,353,110 $
156,787 $ 212,557 $
51,288 $
8,160 $ 43,330 $
-$ -$ -$ -$ -$ -$ -
$$$$$$-
UCHSC Expenses JCML Expenses
Total Operating Expenses:
$
1,825,231 $
$ 49,500 $ 2,066,750
160,780 $
2,116,250 $
$ 60,000 $ 1,345,200
4,102,261 $
1,405,200
Sub Contracts:
Fudan University
(1 ) $
5,121,580 $
-$
252,000
$-
- - -(J)
IPHSC (2) $
170,077 $
$
$
- - -I
SMCDCP (3) $
153,004 $
$
$
-m
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EMBSI (5) $
2,515,754 $
$ 730,550
$ 730,550
r
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s: -()
(Cincinnati) (6) $
336,834 $
$ 48,562
$ 48,562
- - -()
Histology (7) $
$
$ 3,000
$
r lotal :sub
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Contracts:
$ 8,297,250 $
1,229,168 $
1,034,112 $
10,560,530 $
779,112
- -G)
Travel:
$ 9,218 $
500 $
$ 9,718 $
oI Equipment:
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Capital Equipment: $
1,383,491 $
$
~lJTODATE
ex>
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Projected totals 1213112007
$ 4,462,721
$ 5,507,461
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$ 11,339,642
G) $ 9,718
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SH ELL-MCCLU RG-062783
lotal Expenditures: I Olal \.:irant Funding:
Other Costs:
Total Equipment:
Shi ppi ng/i m portati on
$
Indirect Costs:
lotal Indirect Costs:
Overhead: $
Other:
$
$
$
I-ield Expenses
$
$ 1,383,491 $
1,129,984 $ 1,129,984 $ 15,051,530 $ 15,761,880 $
1,181,486 $
-$ - $ -$
105,842 $
73,992
105,842 $ 1,742,094 $ 2,000,000 $
73,992 $ 4,123,757 $
570,889 $
1,383,491
$ $
-
$ $
1,309,818 $
20,917,381 $
18,332,769
79,778
-
79,778 3,175,247
131,000 $
100,942 $
1,413,428
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AUTODATE
.,1:::0.
$ 1,383,491
$ 1,389,596 $ 24,092,628 $ (5,759,859)
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1570872
1047248 523624
3141744
2094496 523624
5759864
1909053.818 1272702.545 636351.2727
3818107.636 2545405.091 636351.2727
6999864
2072690.182 1381793.455 690896.7273
4145380.364 2763586.909 690896.7273
7599864
AUTODATE
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SH ELL-MCCLU RG-062786
IExpenditures:
Personnel:
Total Personnel: Operating Expenses
U(;H:S(; liHAN I
Accumulative Actuals to date
06/30/06
Projected for 07/01/06 to 12131106
Projected for 01/112007 to 06/3012007
Projected totals 07/0112007
Personnel at UCHSC: $
Personnel at JCML $ Other: $ $
Expendable Supplies: $
Non-capital Equipment: $
Services $ Maintenance: $ ME feasibility
Study: $ Contingency: $
2,402,457 $
-$
3,900 $ 2,406,357 $
1,353,110 $
156,787 $ 212,557 $
51,288 $
8,160 $ 43,330 $
245,804 $
-$ -$
245,804 $
-$ -$ -$ -$ -$ -$
235,083
664,320
-
899,403 $
-
3,551,564
Total Operating Expenses: Sub Contracts:
UCHSC Expenses JCML Expenses $
Fudan University (1 ) $
IPHSC (2) $ SMCDCP (3) $
EMBSI (5) $
1,825,231 $
5,121,580 170,077 153,004
2,515,754
$ $ $ $
$ $
160,780 $
49,500 2,066,750
2,116,250 $
-$ -$ -$ -$
252,000
-
730,550
4,102,261
Children's Hospital
-(J)
(Cincinnati) (6) $
336,834 $
$ 48,562
- -I
Histology (7) $
$
$ 3,000
m Total Sub Contracts:
$ 8,297,250 $
1,229,168 $
1,034,112 $
10,560,530
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() Equipment:
()
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1,383,491 $
$
;a Shi ppi ng/i mportati
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-$ -
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$ 1,383,491 $
-$
-$
1,383,491
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Indirect Costs:
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1,129,984 $
105,842 $
73,992
AUTODATE
-.....J
Projected for 07/0112007 to
1213112007
Projected totals 1213112007
$ 246,837 $ 1,064,320 $ 1,311,157 $
$$$$$$-
$ 60,000 $ 2,185,200
$ 2,245,200 $
$$$-
$ 730,550
(J) $
48,562
-I $
m $ 779,112 $
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79,778
4,862,721
6,347,461
11,339,642
9,f18
1,383,491
AUTODATE
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SH ELL-MCCLU RG-062789
100ai Expenditures: lotal urant Funding:
Other Costs:
Total Indirect Costs:
Field Expenses Post Study Work
Other: $ $ $
$
1,129,984 $ 15,051,530 $ 15,761,880 $
1,181,486 $
105,842 $ 1,742,094 $ 2,000,000 $
73,992 $ 4,123,757 $
570,889 $
131,000 $
100,942 $
1,309,818 20,917,381 18,332,769
1,413,428
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SHELL-MCCLURG-062791
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Table I. UCDHSC Plan A- Study Completion
Currently Funded
IPijiiQi'li'lijl
Proposed Budget
--- ---
- - -- ---
Proposed Budget
. _._-_.
. ------
259,611 195,125
$4,300,509 3,281,235
Difference between Currently Funded and Proposed UCDHSC Budget $ 1,019,274
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Plan B Total $ Subtotal UCDHSC + Plan A + Plan B $
1,240,000 6,999,864
Plan C. Additional Post-Study Publication Costs (2008-2009)
Total:
$600,000 $7,599,864
Budget
Jan-07 Feb-07
$ 258,852 $ 255,852 $
Fudan $126,000 $ 12f3,000 $
EMBSI $ 121,758 8121,758 $
Cincinnati $ 8,094 8 8,094 $
Histology $ 3,000 $
- .~..
Mar-07 129,852 $
-$ 121,758 $
8,094 $ -$
Apr-07 May-07
129,852 $ 129,852 $
-$
-$
121,758 $ 121,758 $
..8,094 $ 8,094 $
-$
-~
Jun-07 129,852
-
121,758 8,094
-
Jul-07 $ 129,852 $$121,758 $ 8,094 $-
Auq-07 $129,852 $$121,758 $ 8,094 $-
Sep-07 $ 129,852 $$121,758 $ 8.094 $-
Oct-07 $129,852 $$121,758 $ 8,094 $-
Nov-07
$ 129,852
.~.. -
8121,758
8 8,094
$-
Total: Dec-07 Costs $129,852 $ $ -$ $121,758 $
..$ 8,094 $
~ -$
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SH ELL-MCCLU RG-062795
Cases (WHO) & Questionnaire CC study
AML Lymphoid MDS AA BP
UCHSC GRANT Accumulative Actuals to
date 06/30/06 519-? 520-? 379-? 132-? 32-?
Test data set
unacceptable
Projected for 07/01/06 to 12/31/06 87 87 63 22 5
Projected for 01/112007 to 06/30/2007 87 87 63 22 5
Disease progression
Analytical approach Study report
dose response
not started not started
Molecular Epi
Exposure Assessment
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molecular lesions progmosis
% follow up success
dose reponse biomarkers
polymorphisms metabolites
Questionnai res Factory visits
Sector analysis IPHS review Database
translation and query
Supported
25
6000 50
shoe making
% complete yes
painting, rubber, home remodeling
machine maintaince, printing
yes yes
Projected for 07/01/2007 to
12/31/2007 0 87 0 0 0
Projected totals 12/31/2007 ? ? ? ? ?
complete
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Personnel:
Total Personnel: Operating Expenses
Total Operating Expenses: Sub Contracts:
~~ ,~~ \.:iHANI Accumulative Actuals to date
06/30/06
UCHSC GRANT Projected for 07/01/06 to 12/31/06
~~"~~ \.:iHANI Projected for 01/1/2007 to 06/30/2007
Personnel at UCHSC: $ Other: $ $
Expendable Supplies: $
Non-capital Equipment: $
Services $ Maintenance: $ ME feasibility
Study: $ Contingency: $
$
Fudan University (1 ) $
IPHSC (2) $ SMCDCP (3) $
EMBSI (5) $
2,402,457 $
3,900 $ 2,406,357 $
1,353,110 $
156,787 $ 212,557 $
51,288 $
8,160 $ 43,330 $ 1,825,231 $
5,121,580 170,077 153,004
2,515,754
$ $ $ $
278,515 $
-$
278,515 $
-$ -$ -$ -$ -$ -$
400,000 $
850,989
-
402,075
$ $ $ $
278,515
-
278,515
-
250,000
425,495
-
407,700
Total Sub Contracts:
Children's Hospital (Cincinnati) (6) $ Histology (7) $ $
336,834 $
-$
8,297,250 $
58,800 $
-$
1,311,864 $
61,740
-
894,935
Travel:
$ 9,218 $
500 $
-
Equipment:
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- -I
Equipment: $
1,383,491 $
$
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$
s: - -I
Total Equipment:
$ 1,383,491 $
$
() Indirect Costs:
-()
Overhead: $
1,129,984 $
r
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Total Indirect Costs:
Other: $
1,129,984 $
176,544 $
137,414
G) Total
oI Expenditures:
$ 15,051,530 $
-
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15,761,880
1500000
l~m ATE
UCHSC GRANT ENDS Projected totals 06/30/2007
$ 2,963,387
$ 2,475,231
$ $
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10,504,049 9,718
1,383,491
1,443,942 18,779,817 18,332,769
AUTODATE
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SH ELL-MCCLU RG-062800
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SH ELL-MCCLU RG-062803