Document 1x754VN90BXkq9k0bajGbReo

MANUFACTURING CHEMISTS ASSOCIATION 1625 CONNECTICUT AVENUE, N.W. WASHINGTON, D. C. 20009 (202) 483-6126 GEORGE E. BEST VICE PRESIDENT TECHNICAL OtRECTCR April 13. 1973 To the Management Contact a,.of^Cpnipaai^S, Sponsoring ' CONFIDENTIAL j ^/ Sf* VL\#~ f A. R. Adams, Air Products W. s. Ferguson, Allied H. L. Schmidt, Jr., Borden C. A. Brighton, BP Chemicals J. D. Bryan, Conoco Chemicals H. E. Connors, Diamond Shamrock D. C. Nuechterlein, Dow W. E. Rinehart, Ethyl G. W. Hunter, Exxon Chemical J. H. Rosenson, Firestone Anton Vittone, B. F. Goodrich D. H. Francis, Goodyear George Roush, M.D., MonsantoMac Roy Gasque, M.D., Olin R. E. widing, ppg Industries R. J. Reynolds, Shell Chemical L. B. Kuhn, Stauffer Marvin Rosen, Tenneco A. B. Steele, Union carbide C. D. McCleary, UNIROYAL Dear Sirs: Concerning the program - (1) Animal Testing Your technical representatives deem it most important to add to a group of animals which will have food and bedding in the inhalation chamber as in the European program, in order to obtain an indication as to whether sorption-desorption or reaction products affect the results. This would increase the cost by $15,000 (changing the project budget from $165,000 to $180,000). Some of you have al ready indicated specific approval. For the rest, we will assume you approve unless you object, in view of the relatively modest amount involved in each company's proportionate share and the fact that this extension calls for no increase above the original com mitments . (2) Epidemiology Study Although responses to my December 21, 1972 letter were less than unanimous in favor of proceeding immediately to RSV 0000399 Management Contacts of companies Sponsoring VC Research Program April 13, 1973 Page Two an epidemiological investigation, events in the interim have conspired to increase its desirability. Messages of approval and funding commitment have been received from all of the 17 participating companies represented at the April 4th Technical Task Group meeting, and I am corresponding with the other three. We are now in a position to expedite getting this under way. You will be interested that the companies sponsoring the European project wish to contribute their epidemiologic data, hoping that such enlargement of the larger worker population will add to statistical significance. (3) Executive-Leve1 Consultation No objection was raised to undertaking the first step of the proposal described in my letter of March 26, 1973, namely, executive-level consultation concerning the European research observations, and plans are proceeding. You will be kept advised Sincerely, GEB:gr cc: Technical Task Group on Vinyl Chloride Research (Participating company representatives only) Dr. K. D. Johnson RSV 0000400 c