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' . \ .....
1011 '."s- ~IA~Vl I.LE CoHPOHATTO~
~
'
Dece.nber JO,, 1957
Mr. Ivan Saoourin St. Jonns
~ebec
Re: I.H.F. Survey
Dear Ivan:
.[
you
sent
Hugh Jackscn and I have reviewed the us. we have noted deletion of all
coudensation
of
the
survey
which
asbestosis and lung cancer in fonr.ation is of great scienti
tnis
condensatrieofne.renWcheisle twoethbeeliaesvseoctihaatitonthoisf
in-
Q.A.M.A. to
&Bbestosis.
emphasize
the
expofiscurevaoluf et,hwe eascbanesutonsdemrsitnaenrdanthdendoet stihree
of the cas
emoking
and
We also are lung cancer.
in
agreement
with
the
deletion
oi
the
es of reference to
criticism
It must be recognized, when publisned becau5e
however, that this re~ort all other authors toda
will
be
subjected
to
ana cases of asbestosis. miners, greater emphasis
If ~e should
are to restrict be placed
this
y correlate lung cancer condensation to asbestos
ing the conort. The fact that all members oonfththee cchoohicoertohfadwo5rdos rumseodreinyeaaersfino-f
exposure to asbest.os st1ould be reiterated.
Following are comments on certain paragraphs of the condensation.
one
has
We believe the first written so extensively
sentence in - - - -"
paragraph
2
should
read
"Perhaps
no
Page 14
expanded toInemthpenatshizierdtnseant tennocne-exopfopseadragptr.a:rpshon2netlhwe edreefinition of cohort should be
l'h.i.s migt1t be done by aoding
other non-exposed ,ersonnel,
a sentence
regardless
similar
to
not included
the follcwing:
in the sample. "Office and
1
in tht:: conort 11
of length of e.'T.ployme:nt were not incluaed
sentence posu
To of
p
fu ar
rt!1er agrapn
em}.-nauize 2 might
r
t e
n a
e d
,
e
xo 11Al
s l
ure wo
aspe rkers
ct w
i
of th
the miners the
more tnan 5
second
re were placed in one of three categol'ies 11
years of ex-
graph, "As 1pt rmeviigohut sblye n&odtveidsciw.bolerkteors awdditha."nlootheexrpsoeunutreen-cweerae tntohteinecnld'ldoefdthinisthpearca.-iata".
._,. I
-'.;:Ttr. Ivan Sabourin
- 2-
December 30, 1957
Page 23
cance".
In the fourth sentence reference This phrase 'Was explained clearly
:Ls ma.de to "the
and thoroughly
95%
level
of
signifi-
wseasctidoenletoendSitnattihseticcaonl dMenesthaotdiosnowfethfeeeol riginal 3\lrvey.
on Pai:es 23 to 25 jn the
Becau~e tliis wnole section
note the
meaning
of
"the
95t
level
of
it i;;ight be
sig~ficance 11
advisable
to
explain
by
foot-
change.
We feel "However,
t
h h
at av
i
th ng
e
f
fifth ound
j
sen ust
t
en 12
c
e c
mi ase
gh s,
t b we
e
~4de
are n
s ot
t
r
o
n
g
e
r
by
the
f ollcwing
ltuhnerge.cfaonrecetrhtehahnypdootehsestihse thgaent earsabl epsotopsulmatiinoenrscadonnnoot tbeharveejeaacbothevigdeh"e.t1h ims olertvaelilt,yafnrdom
Page 41
age group. ThIentathbeleoirnigtihneal csel.nl.It'Versyotfhtihseraptaegewsahsow2s7. a rate of 2(1 in the 45 - S4 Page 48
substitutioInn othfethlae swt osrden1t1eunncoe.erotafkethne11 ffoirrstthepawraogrdrap11chowmernwisosuioldnedlj11~..e to suggest the
el6111ents
In the second sentence of paragraph 3 of the cohort uefinition be repeated.
we "A
would like cohort was
to
suggest
tnat
the
cionlfudathesdebeiisnntodtsuhsemtriysnteudrdsuyrih"na.gvin1g95a0t. leOanslyt 5thoyseearws oorfkeerxs pwohsourme eitnththesee idncedrfiisntteerydriaaa~swdaewreghoroinuwp-ere
P~e 49
wtiaosndoefletthedeInipnthhrteahseelac1s1wot ni:sdiecehnntsehanatvcioeenbo. efenpa.erxapglra~inhedl wine swoomuelddleitkaeil"tosisnucgegessutchtheexdpelalen-ation
Dr.
Braun
This publication should form snould be asked to establish
the the
basis
fr~m
for
futu:.e
surveys
a.nd
reports.
Grainger anci cohort coula
Cartier so that each be reported to the
yea:r
the
m1ork
status of
of reporting ~very member
for Deeters of the origin~l
study be analyzed because nowr.ere
by
their
Industrial hygiene Foundation experts. We ca.r>-.1."lot emphashe this
and tnc cont:.nu1ng point too strongly
valuable
ana
in
hich
the literature today is there approY.i.-nates this mae::U.tude.
reported
a
study
wr.ich
is
so
probably
We agree wi. th Doctors Cartier have some asbestotic fibrosis
and Braun that a certain which cannot be diag
nu:aber
of
w0rkers
fortunately, we means of making
cannot take a diagnosis
lung biopsies before there
on
all
workers
nosed by :A-ray. Unand we have no other
study
of
all
exposed
asbestos
workers
a!'e x-ray cha.."lges. 'r.11erefore becomes increasingly important.
the
annual
for
this
'We feel that very valuable
Dr. Braun a.'1d his staff are contribution to our medical
to
be
congra.tulat:.ed
heartily
reefcfovgrntsizewdiljlvbuernraelw. arded in the near future by the plmuobwlilce/)di9tPion 'oWfe tt.riulisstwt::hirkatinthaeir
//
Since,r J
K nncth W. Smith, M.D odical Director