Document 1gR0XeQgnyj7OYok5jYoaMymm
FERIAL SAFETY DATA SHEET
jma Chemical Co. 0. Box 14508 . T.ouis, MO 63178
: 314-771-5765
Aldrich Chemical Co 1001 West St. Paul Milwaukee, WI 53233 Phone: 414-273-3850
Inc. Fluka Chemical Corp. 980 South Second St. Ronkonkoma, NY 11779 Phone: 516-467-3535
cabase Version May 01, 1996
CTION 1. --------- CHEMICAL IDENTIFICATION- - - -
CATALOG #:
E9129
NAME:
ETHYLENE GLYCOL
CTION 2. ----- COMPOSITION/INFORMATION ON INGREDIENTS
CAS #: 107-21-1
MF: C2H602
EC NO: 203-473-3
SYNONYMS
ATHYLENGLYKOL (GERMAN) * 1,2-DIHYDROXYETHANE * 1,2-ETHANDIOL * 1,2-
ETHANEDIOL * ETHANE-1,2-DIOL * ETHYLENE ALCOHOL * ETHYLENE DIHYDRATE *
ETHYLENE GLYCOL (ACGIH) * GLYCOL ALCOHOL * LUTROL-9 * MACROGOL 400
BPC * M.E.G. * MONOETHYLENE GLYCOL * NCI-C00920 * NORKOOL * TESCOL *
DOWTHERM SR 1 * UCAR 17 *
CTION 3. ---------- HAZARDS IDENTIFICATION ---------
LABEL PRECAUTIONARY STATEMENTS
TOXIC (USA DEFINITION)
HARMFUL (EUROPEAN DEFINITION)
HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
RRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
*(EPRODUCTIVE HAZARD.
TARGET ORGAN(S):
KIDNEYS
LIVER
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION. ZTION 4. ---------- FIRST-AID MEASURES- --- ----- _____
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
CTION 5. --------- FIRE FIGHTING MEASURES ----------
EXTINGUISHING MEDIA
WATER SPRAY. CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
.PREVENT CONTACT WITH SKIN AND EYES.
:SUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS. CTION 6. -------- ACCIDENTAL RELEASE MEASURES- ------
WEAR RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY
RUBBER GLOVES. ADSORB ON SAND OR VERMICULITC AND PLACE
DISPOSAL.
ncc-n CONTAINERS FOP DO A 061785
CONFIDENTIAL
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
CTION 7. ---------- HANDLING AND STORAGE- ----------
REFER TO SECTION 8.
CTION 8. ------ EXPOSURE CONTROLS/PERSONAL PROTECTION- -----
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
.ECHANICAL EXHAUST REQUIRED.
SAFETY SHOWER AND EYE BATH.
DO NOT BREATHE VAPOR.
AVOID CONTACT WITH EYES, SKIN AND CLOTHING.
WASH THOROUGHLY AFTER HANDLING.
TOXIC.
IRRITANT.
REPRODUCTIVE HAZARD.
KEEP TIGHTLY CLOSED.
HYGROSCOPIC
STORE IN A COOL DRY PLACE.
CTION 9.--------- ---------------- PHYSICAL AND CHEMICAL PROPERTIES - - - ----------------
APPEARANCE AND ODOR
VISCOUS COLORLESS LIQUID
PHYSICAL PROPERTIES
BOILING POINT:
196 C TO 198 C
MELTING POINT:
-13 C
FLASHPOINT
>230
109C
EXPLOSION LIMITS IN AIR:
UPPER
15.3%
LOWER
3.2%
AUTOIGNITION TEMPERATURE:
752 F
399C
VAPOR PRESSURE:
0.08MM 20 C
SPECIFIC GRAVITY:
1.113
VAPOR DENSITY:
2.1 (AIR=1)
i "'ION 10. - -- -- -- - -STABILITY AND REACTIVITY - -- -- -- --
^.-.COMPATIBILITIES
STRONG OXIDIZING AGENTS
STRONG BASES
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
CARBON MONOXIDE, CARBON DIOXIDE
1 CTION 11. --------- TOXICOLOGICAL INFORMATION --------
ACUTE EFFECTS
HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
VAPOR OR MIST IS IRRITATING TO THE EYES, MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT.
CAUSES SKIN IRRITATION.
MAY CAUSE NERVOUS SYSTEM DISTURBANCES.
PROLONGED EXPOSURE CAN CAUSE:
NAUSEA, HEADACHE AND VOMITING
CHRONIC EFFECTS
MAY CAUSE REPRODUCTIVE DISORDERS.
TARGET ORGAN(S):
LIVER, KIDNEYS
CENTRAL NERVOUS SYSTEM
ADDITIONAL INFORMATION
WHEN INGESTED EARLY SYMPTOMS MIMIC ALCOHOL INEBRIATION AND ARE
FOLLOWED BY NAUSEA, VOMITING, ABDOMINAL PAIN, WEAKNESS, MUSCLE
TENDERNESS, RESPIRATORY FAILURE, CONVULSIONS, CARDIOVASCULAR COLLAPSE,
PULMONARY EDEMA, HYPOCALCEMIC TETANY AND SEVERE METABOLIC ACIDOSIS.
WITHOUT TREATMENT, DEATH MAY OCCUR IN 8 TO 24 HOURS. VICTIMS WHO
SURVIVE THE INITIAL TOXICITY PERIOD USUALLY DEVELOP RENAL FAILURE
.'ALONG WITH BRAIN AND LIVER DAMAGE.
.\TECS #: KW2975000
ETHYLENE GLYCOL
IRRITATION DATA
EYE-RAT 12 MG/M3/3D
TXAPA9 16,646,70
SKN-RBT 555 MG OPEN MLD EYE-RBT 500 MG/24H MLD
UCDS** 7/21/65 85JCAE -,205,86
DO A 061786 CONFIDENTIAL
EYE-RBT 100 MG/lH MLD
NTIS** LMF-69
EYE-RBT 12 MG/M3/3D
TXAPA9 16,646,70
EYE-RBT 1440 MG/6H MOD
BUYRAI 31,25,77
TOXICITY DATA
ORL-HMN LDLO:786 MG/KG
EJTXAZ 9,373,76
ORL-HMN LDLO:398 MG/KG
SMEZA5 26(2),48,83
NR-MAN LDLO:1637 MG/KG
85DCAI 2,73,70
ORL-RAT LD50:4700 MG/KG
GTPZAB 26(6),28,82
IHL-RAT LC50:10876 MG/KG
GISAAA 39(9),106,74
IPR-RAT LD50:5010 MG/KG
KRKRDT 9,36,81
SCU-RAT LD50:2800 MG/KG
NPIRI* 1,49,74
IVN-RAT LD50:3260 MG/KG
KRKRDT 9,36,81
UNR-RAT LD50:13 GM/KG
GISAAA 33(3) ,16,68
ORL-MUS LD50:5500 MG/KG
GISAAA 32(3) ,31,67
IPR-MUS LD50:5614 MG/KG
FEPRA7 6,342,47
IVN-MUS LD50:3 GM/KG
JPETAB 65,89,39
UNR-MUS LD50:8050 MG/KG
GISAAA 33(3) ,16,68
ORL-DOG LD50:5500 MG/KG
RMVEAG 154,137,78
ORL-CAT LD50:1650 MG/KG
RMVEAG 154,137,78
SKN-RBT LD50:9530 UL/KG
34ZIAG -,731,69
UNR-RBT LD50:5017 MG/KG
GISAAA 33(3),16,68
ORL-GPG LD50:6610 MG/KG
JIHTAB 23,259,41
UNR-GPG LD50:11150 MG/KG
GISAAA 33(3) ,16,68
TARGET ORGAN DATA
PERIPHERAL NERVE AND SENSATION (SENSORY CHANGE INVOLVING PERIPHERAL NERVE
BEHAVIORAL (CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD)
BEHAVIORAL (MUSCLE WEAKNESS)
BEHAVIORAL (COMA)
BEHAVIORAL (HEADACHE)
GASTROINTESTINAL (HYPERMOTILITY, DIARRHEA)
GASTROINTESTINAL (NAUSEA OR VOMITING)
LIVER (OTHER CHANGES)
"IDNEY, URETER, BLADDER (RENAL FUNCTION TESTS DEPRESSED)
-- .IDNEY, URETER, BLADDER (OTHER CHANGES)
ENDOCRINE (HYPOGLYCEMIA)
BLOOD (OTHER CHANGES)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
CTION 12. --------- ECOLOGICAL INFORMATION ----------
DATA NOT YET AVAILABLE.
CTION 13. --------- DISPOSAL CONSIDERATIONS ---------
DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A
CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
CTION 14. ---------- TRANSPORT INFORMATION ---------
CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
CTION 15. --------- REGULATORY INFORMATION ----------
EUROPEAN INFORMATION
EC INDEX NO:
603-027-00-1
HARMFUL
R 22
HARMFUL IF SWALLOWED.
S 36
WEAR SUITABLE PROTECTIVE CLOTHING.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
ACGIH TLV-CL 50 PPM, VAPOR
85INA8 6,612,91
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
"'FEREAC 54,7740,89
"vlS HA STANDARD-AIR: TWA 10 MG/M 3 (PARTICULATE)
DTLWS* 3,19,73
OEL-AUSTRALIA:TWA 60 MG/M3;STEL 120 MG/M3 JAN93
OEL-BELGIUM:STEL 50 PPM (127 MG/M3) JAN93
Do A Q
OEL-*t)ENMARK:STEL 50 PPM (130 MG/M3) JAN93
CONFrDFNrr
OEL-DENMARK:TWA 10 MG/M3 JAN93
" TlAi
OEL-FINLAND:TWA 10 MG/M3;STEL 20 MG/M3 JAN93 OEL-FINLAND:TWA 50 PPM (125 MG/M3);STEL 75 PPM (190 MG/M3) JAN93 OEL-FRANCE:STEL 50 PPM (125 MG/M3) JAN93 OEL-HUNGARY:STEL 50 MG/M3;SKIN JAN93 OEL-THE NETHERLANDS:TWA 10 MG/M3 JAN93 OEL-THE NETHERLANDS:TWA 50 PPM (125 MG/M3) JAN93 yEL-RUSSIA:STEL 5 MG/M3 JAN93 OEL-SWEDEN:TWA 50 PPM (130 MG/M3);STEL 75 PPM (190 MG/M3) JAN93 OEL-SWITZERLAND:TWA 1 MG/M3 JAN93 OEL-SWITZERLAND:TWA 50 PPM (125 MG/M3) JAN93 OEL-UNITED KINGDOM:TWA 10 MG/M3 JAN93 OEL-UNITED KINGDOM:TWA 60 MG/M3;STEL 125 MG/M3 JAN93 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV NOHS 1974: HZD 32385; NIS 308; TNF 69314; NOS 174; TNE 743782 NOES 1983: HZD 32385; NIS 340; TNF 102395; NOS 214; TNE 1511087; TFE
446607 EPA GENETOX PROGRAM 1988, NEGATIVE: CELL TRANSFORM.-SA7/SHE; N
CRAS SA-ANEUPLOIDY EPA GENETOX PROGRAM 1988, NEGATIVE: HISTIDINE REVERSION-AMES TEST EPA GENETOX PROGRAM 1988, INCONCLUSIVE: D MELANOGASTER-WHOLE SEX CHROM.
LOSS EPA GENETOX PROGRAM 1988, INCONCLUSIVE: D MELANOGASTER-NONDISJUNCTION EPA TSCA SECTION 8(B) CHEMICAL INVENTORY EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES EPA TSCA SECTION 8(E) RISK NOTIFICATION, 8EHQ-0892-9100;8EHQ-0892-9252 ON EPA IRIS DATABASE EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, OCTOBER 1995 NIOSH ANALYTICAL METHOD, 1994: ETHYLENE GLYCOL, 5500 NTP CARCINOGENESIS STUDIES (FEED);NO EVIDENCE:MOUSE
NTPTR* NTP-TR-413,93 J.S. INFORMATION
"HIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS. __ x ON 16. --------------------- ---------------- OTHER INFORMATION------------ -------------------- ----------------
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH, FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR PACKING. SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE. COPYRIGHT 1996 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC., FLUKA CHEMIE AG LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
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