Document 1QpGxmgKdR2zd40q9JDdbejDX

John Vyvarberg Your Memo 3/20/69 Asbestos Worker* Action Co San Fibrous Clast In A/C Systess t ii -tnmrm -sa.r 3Y srar it cq. ?ui. *i.r *na loraoa *<!. Oc-qoo.r .. ;*. -a af ?, c l. I7-L1J30 Jen 1. Konsan, H.D. A?ril 3, 1969 The following Is la reply to four questions of March 20 and eh analysis of the material glveo by the opposition lo Haatachusaccs and Onio. Z trill oudloa cha concent of cha article and than entire it. Or. Sallikoff's paper discusses the occurrence of asbaaeosls aaong insulation workers exposed to asbestos and not fibrous jlasa exposure. The only coons ction between the two Is chat they are botn fibers. Jc should be pointed ot that asbestos is e natural fiber and la a collective ter* for aany types of tub stance.* At this tiae data la not at all clear on lust wl kind of asbestos trill causa cancer. The problea is also unsettled as to whether the liber nrn#rwi piLt.or whether aoiie fees % arterial on its surfaccee.. In Fibrous glass the product is raleClvely unifora in its basic composition. The binder arterial applied to Its surface In wool products, la an inert substance after It is cured, and lastly tha great bulk of glass fibers produced arc coo large to be consistently taken into the lung. This last point is one of the aost laportaot differences between asbestos, which is readily respirable, and fibrous glass which Is not readily rasolrabla^ y^pallv. asbestos in a period of eooths will cause tuaora in Unlnals A wheraas fibrous alass slaplr llllclta a dusc~ call reaction similar to other inert dusts. Fibrous glass will produce Chs so-called pseudo aabescoe bodies or nors precisely a fcrruglououis body aiallar to those found in asbestos exposure. This hes been demonstrated in missis, but to ay knowledge e ferruginuou* body wicn t.is ceotrel core of fibrous glass has never been deoonstrated in hvaans. (X don't doubt that they occur, but they are probably relatively infrequent, sines very few fibers of glass reach the lung tleeue and secondly, only a percentage of thosa fibers will ba expected to form the ferruginuoua bodies.) PLAINTIFF'S EXHIBIT V 02 401 0475 John Vyverbarg -2 ?ro<jueo?#-a1i *i-Y octsor t i. *J-" ;jo iS .M'.ian * ft i Pi 3 '*"' Dr. Cross hu pointsd out that the ferruglnuoua body la a nonspecific reaction that has no psthologicel significance. Our fiber glass haa always had tha potential to produce theaa bodies u evidenced by the fact that Gardner reported the* la relation to fiber glass as early as 1942 la experimental animals. Tha second paper. Or. Tneodoa' paper. "Lung Biopsy and Diagnosis of Pneuaoconloeis", simply reviews the diagnostic capabilities of a lung biopsy to diagnose a variety of possible path ological conditions. Dr. deTrevllle has wall pointed out that tha so-called fiber glass pneumoconiosis cited in the Taeodos* paper was inaccurate from a standpoint of pathological diagnosis, sines silicosis had not bean ruled, out and refined techniques demonstrated that glass was not present in the lesion. The docunentstioo of the environmental exposure was nothing sort than a auppoaition aod-noc bacLedby-caraful-aiwiroftaeotal questlbQihg of tha patient. - Tha next group of article*, such aa Taylor's paper, "Asbestos Workers Hit by Kara Fore of Cancer", and Borden'a Vev Torker article, keporter at Large, "The Magic Mineral", All of these things deal exclusively with asbestos and not fibrous glass. X have already indicated tne difference between the two floors. When Dr. Seililtoff addressed tha Asbestos Workers, ha indicated that it takes upwards.'of 40 to 50 years to product a owe types of tuaora in huaarvs wnen :* exposed to esbestos. This la true, but it doesn't necessarily take this long. There have been reported cases in less clot than this and'snothar important aspect is that cancer haa been produced mgertaentally in anleals in as short as four to six months with asbestos. NcTnvescigator has yet been able to produce cancer with fibrous glass. This coupled with the fact that there has bean no demonstrable disease in workers exposed to fibrous zlasa. It is of interest that at the Legislative Wearing la Massachusetts Che fact Chat fibrous giasa was found to be sticking out like porcupine quills was not used. This charge appears to be used only wlehia the confines of the Union meetings, X believe that Dr. Seilikoff may have examples of tose fibers of glass in lungs, but X would suspect tna t these fibers era simply "laying" there without any adverse tissue reaction around them. It is probably alao difficult for him to locate these particles with regard to vnetner they are lying in the breathing tubes or if they're in tne sir secs. Dr. Cross haa satlculously dissected ten lungs of fibrous glajs workers and it ax not been able to daaonatrata any pathology which could be related to fibrous glass exposure. Dr. Sallikoff has been asking this statement for over a year trow. Therefore, if he did know pathological entity. X strongly suspect he would have published. 1 think the atxt time tits question of tna por cupine quills in the luajs coats up h* should be encouraged to publish his findings in tha medical literature. If you notice, ha is vary ,careful not be quoted directly on this particular statement. X suspect if he ware becked into a comer he would slrtply have to admit ha has found Hat fibrous glees lying in tne lung as X mentioned earlier. 02 401 0476 John Vyverberg ) ?rs<auc#d -mmrm jndr tL ay orC#r at -cicjg ?u. *i.gy 4nd Ooraoa M449, 13 :4aA*^l^?; Z will now save. ever to the Information presented *t the Green Township Local ocnool Board. The sources of information were Mt. SLnal Hospital Softool of Medicine, which was elsply Sr. Sslllkoff end hie supposition that there eight be a problea. Again In tftls he uses the fealllar scare tactic, "well we really don't know, since enough tlae nee not elapsed to determine If very long after exposure to fibrous *lase could cause cancer devclopeent* Cancers, Ilka most other biological systems, are subject to varying circumstances, forty years ear be an avars-a for a tumor to ahow up In a hioan. but It la reasonable to baliova . ^ that a tuaor could show tin In * ,.rh ^Sorter n*- ^inee we nave had worktre exposed for up to thirty years wlrnout dcaonstrabla tuQora. counlad wleh the fact that we cannot produce tueora In an las Is, wa are on reasonably safe around to sv *'* ^i. Tl ftrplt rnn tlrr 1 the fact that certain apsclea of anixals do not produce cancers, while others do and tne fact that eaterlals with disease producing abilities have demonstrated these capabilities only after many 7ars reaoved from tne ex posure can be refuted on the baala tnat wa have learned our laasoo from previous nlstak.es. A variety of species and tecnnlquea to look at tne health aspects of fibrous glass vers eaployed, again showing no adverse affect. The JeffersoQ Medical College, Philadelphia, ftnna. reference waa simply Dr. Theodos* article which was nentlonod earlier. The English reference, The University of Vhitekmights Park, Reading, England, la >ei3?ly a report Indicating the ability to produce ferruglnuous or aabcstoa bodlea in anlaala. Again, I point out Gardner in 1942 and a variety of otner investigators, including Cross, have also been able to do title sane thing. Tne bureau of Laboratories, Department of Health, Washington, D.C., Z assume la where Dr. Scneppers is now located. Dr. Sencroers wrote articles In 1935 and a^alo In 1937 on the health aspects of Inhaled fibrous glass. His studies did not hava adequate controls nd what ft* .. m wei^. have been changes found In rata wh. a. v .rs exposed to no substance ot-ter than rooa sir. Hie studies have little validity, "tils 1937 study waaTwlth regard to fiber ilsaa reinforced plastics which are not applicable tb *j wool products. *" '"" " ^ With regard to Inviting Dr. bright to neat with top management In our company and propose additional research. X do not feel thie le necessary at thle tine. My rtasona for this eras m * uiTj^'We have adequate laboratory, clinical, eplJenlologleal and ^`-""'envlronxeDtal Investigation which la either completed or wall underway at thla tins. 02 401 0477 Join Tyverberi 1 ?ro4uc*4 lABftJLA -ifldr i4* oy o;;r ot ;j<3<3 ?*ul aa orcoa Mq, > ;r:rr.4!Lii;s*-ia 2* Thle research la balog carried out by ea crassly eoapetent research personnel. Including represen* tstlvee of the Federal Covernaent. 3. Any auch rasaarch would taka an additional acveral years and would (Isa our opponents additional fuel to aay vs really don't know whether It will causa sarlous disease. 4. Xt la axtraaely dlfftcult to find. a population with* ^ high. exposure te^flhro-u* glaaa with th exclusion of E ether SatarliTa. such as asbastoa. *'a' are already examining the only known such. roup In the epldexlologlc atudy carried out through NL-CA by the Public Health Service. k JLA/sb Jon L. fconien, rt.D. 02 401 0478