Document 1QozZ15j4pN9yY1x2kjVQbeDa

June 25, 1 9 i*7 Dr# Kenneth A. Koerber The Electric Storage Battery Cmpany Allegheny Avenue and 19th Street Philadelphia 3 2 , Penna. Dear Dr. Koerber: I am sending you herewith duplicate signed report giving the analytical results on your two patients, t f l H B and I send also a bill to cover of the analyses in these two cases. I have made the necessary notations on the analytical reports. In t h e s c a 8 e s o f t ^ m ^ 1 have no clinical record and am Interpreting the results^therefore, merely at their face value. In the case of will probably be aur- prised to find that there has been no very significant decrease in the lead concentration in the blood. Under these circumstances, you will recognize, I trust, that the sharp decrease in the urinary lead concentration is not to be regarded too seriously. If we were to take a series of samples on this man, we should find a wide fariation In the results, with the average very much higher than the present result. It just happens, by sheer chance, that the sample in this instance has yielded a low value. I point this out, since it is nec* essary to recognize that lead la lost from the body slowly. It least six months would be required, in a case of this type, to bring about any very serious de crease in the rate of-lead excretion; and In the lead concentration in the blood; when the individual has been removed completely from any chance of occupational expo sure. If the exposure is merely reduced, the excretory rate may remain constant from there on. That is, it takes very little continuing lead absorption to maintain a high level of lead excretion, In the case of the person who has accumulated rather large quantities. These facts, which we established only after prolonged study of human lead metabolism under laboratory conditions, are quite contrary to those generally accepted. The belief Is very strong that the rate of lead elimination from the body, as well as the level of lead concentration In the :lood, drops off rapidly following cessation of exposure. All of the wise boys raised their eyebrows some ten or twelve years ago, when I stated that twelve to eighteen months might KfT 0004126 2 be required to re'store these findings to normal levels. The fact Is, however, that the time recuired to eliminate stored lead is determined largely by the quantity stored, as Influenced by the length of time over which the stor age or accumulation takes place. In any case it takes Ion, er to get rid of the lead than it does to accumulate it* : Cordially yours, Robert /u Kehoe, M. D. RAKsEK Enclosures b 0004127 HfWJie: Material Urine and Blood by P-r. h.A. Koerber, Electric Sfcor&r battery Company, ?hllacmlphta , Pa* , Lead Analyses Analysis ii'umber VoiniSB: Specific Gravity Mg*. Pi>/liter 11.7^-5888' - 100 ml*. - 1.017 - 0.13 ' SLOOP " ' .. ,:Analysis Knmoer - k7&*3&*9' '. ; .eight'' , ' - 20.0 Grams Ef'. Pb/100 Grama - O.095 (Dithisone) The Lead concentration In the lc-j is sell above normal limits, while that In the urine is approach! n;normal levels. in; Is evident,' fioni tac ava'laMe records, teat this ms--.- has absorbed rate' lsrre quantities' 'of lead .in the course of .his previous oik, . and that a .considerable! per led or freedom.'iron.fur- t M r exposure r*ill re ret *Iren by restore- hlir. to .nor- . rxtl lead levels in .blood and; urine* . ... . olrned* ' __________ Samples Collected: Samples deceived: 6-11-1*7 Samples Reported: 6-17-1+7 Same : Material Suomitted Enquired : Urine and Bisod 6-9-147 toy Electric Storage Battery Co*, rhiia*, Pa. Dead Analyses CKT B ' Analysis `lumber olnme Specific rarity . %. Pto/Liter , - li-7 A-5 ^ 6 9 - k9 ml. - 1.0J2 - to. 50 Analysis Humber Grams - , Pb/lOO Grams f,-.'Pto/100 (trams - I4.7A-587 - ?.? r 0.095 (Spectro; rapid.c) - O.O85(Difchizone) The lead concentrations lc r.otto blood and urine.are well at.ove normal levels,' and are indicative .of rece t .hazardous lead exposure. .In the presence of characteristic clinical findlots, these analytical results would Justify & diagnosis oi' lead intoxieaf1on le- Samples Received 6-9""4? Samples Reported 6-114.-14.7 K f 0004129 N 6865.02 jfaMmVS.A. FTM n53~3~4?-G . MEMORANDUM OF SHIPMENT Ctigofeo dispensery E.S.C. Order ' -. ) Number X " 0i19. Cusiomsr's Ordsr Dato ' . _ Shipped o--0--47 G3 . Macia By Sh!| THE ELECTRIC STORAGE BATTERY GO. PHILADELPHIA 32,.PA. Robert . Kehoe MB. Kettering Lab-5 University Of Ginn ) Cincinnati'-19, Ohio. Shipped Via Parcel Post, 33# Special Handling f.O.B. Factory ) Transp.Chop, CASE No. prepaid - Packeges CONTENTS ~~ Pounds Gross 1 Round .Container With Specimen Of Urine - 1 Round Container VsTtii Sp*ecimen Of B-loo d . '-. V-'T-S-iV' : 1 . .1 .. ' . . 1-4S Fibr `V'v *y. 3 l-P0-.998fc0 3 Lbs. Or. HE 0004130 N 6865.03