Document 1QBEkN7bYVeJoMVEmdOapywKa
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I MONSANTO COMPANY
cc `"'Mas
Sc. Louis, Missouri
A. Bryan
Christman
Early - Washington
. Graham
LEV. DEPT. CALL REPORT NO. 40-67
. Heininger _F'Ll
. Holland
DeV:-,
Hunt
. Keller
. Kosup
Food L Drug Administration
. Pollart
v*'S.snxr.g*, D.C.
Tifft
LATE C? CALL:
May 11, 1967
df: PC - PDA
tr
PC - Binders - Coatings
FOR PDA Heroert Blumenthal Vuillard Orr K. P. Misra Joseph McLaughlin Al Holtz
FOR MONSANTO Wm. HUnt
Robt. Keller M. V. Merchant
PURPOSE OF CALL;
To review extraction data on pigment binder PB-702.
This meeting proceeded smooth!^. A cursory-review of our data brought forth a favorable response that we should proceed to submit a petition for approval. Additional information was requested pertaining to characterization of the polymer film and analysis of the emulsion for free acrylamid.
D-iTAxLS :
The meeting opened with a review of coating applications to paper and
paperboard and the methods employed by Monsanto to prepare papers for extraction. The makeup of o^r polymer system was also discussed. A series of questions which werte asked by the PDA personnel included:
"Have you supplied validation for your analytical procedures?"
"What coat weights have you applied and why this level?"
"Have you tested the emulsion for free acrylamid?"
"Will you provide polymer characterization data?"
"What solvent may be used to dissolve or swell your polymer?"
In summation, it was suggested that Monsanto proceed to file a petition zo modify the sections of the Federal Register pertaining to use of chemicals in the manufacture of paper and paperboard which will come
into contact with dry, aqueous and fatty foods. Information to be
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PDA - Dev. Dept. Call Report No. 40-67 Page 2 added to the report should include polymer characterization data, such as molecular weight and solvent swelling data, also viscosity of the emulsion and finally the analysis for free acrylamid in the emulsion. On the subject of analysis of free acrylamids in the emulsion, it was pointed out that techniques for analysis had been published by Hercules and Dow in their previous petition to PDA for wet end addition of poly acrylamid polymers. They agreed to provide us with information on this analysis but stated that our results might, be different based on the effects of different extraneous`materials.
M. V. Merchant /ds
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