Document 1Q84JgE5w3yGKkBq9wMkoMQOq
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DEPARTMENT WORKED BY AGE AND BY EDUCATION
fZ X T s.e.(n)
45.41 - 1.47(44)
1236/237 J - a.a.(n )
43.20 - 1.60(56)
Education < High School High School Graduate Son Collage Collepe Graduate +
1 7 15.91 27* 61.36 10 22.73
i 8 14.29 23 41.07 17 30.36 B 14.29
pvalue 0.3219
0.01 4 0.05
C2S621
V
I TABLE
DEPARTMENT WORKED v OTHER DEPARTMENTS WORKED
Worked in #262 Worked 1n #268
#236 (n=44)
#%
12 27.27
8 18.18
#236/237 (n*56)
#%
7 12.50
2 3.57
p-value
0.0754 0.0203
C2362; i
Ii
TABLE DEPARTMENT WORKED v PREVIOUS EMPLOYMENT EXPOSURES
Previous Employment Exposures
Hechinleal Work Farming Dust Solvents Cutting 011s Weiding/Soldering fumes Fertilizer Weed K ille r Asbestos Animal Feed Radiation Rubber Additives
#236 (n-44) # X Yes
15 34.09 2 4.55 20 45.45 15 34.09 10 22.73 13 29.55 5 11.36 ' 5 11.36 1 2.27 2 4.55 1 2.27 1 2.27
#236/237 (n*56) X res
17 30.36 0 0.00 24 42.86 24 42.86 18 32.14 15 26.79 7 12.50 6 10.71 2 3.57 1 1.79 1 1.79 0 0.00
0- value
0.6911 0.1070 0.7951 0.3723 0.2979 0.7603 0.8622 0.9179 0.7055 0.4219 0.8629 0.2569
C2 6 ? '
TABLE ____ DEPARTMENT WORKED v TOBACCO AND ALCOHOL USE
Sooklnq Status Haver Former Present (Unknown) .
Alcohol Status * Haver
Former Present
Pack-Years*
Former Smokers Pack Years
Present Smokers Pack Years
236 (n*44) i X Yes
14 32.56 11 25.58 16 41.66 0)
4 9.09 4 9.09 36 81.82
X - s.a.(n ) 15.60 3.52(39)
13.56 - 3.66(9)
30.41 - 6.55(16)
#236/237 (>>56)
X Yes
p -vtl tie
8 14.55 13 23.64 34 61.82
(1)
0.0694
3 5.36 7 12*50 46 82.14 X - s.e.(n ) 21.81 - 3.29(51) 17.31 i 5.00(13) 29.56 - 4.53(30)
- 0.6868
0.2045 0.5694 0.9167
C2362-
Family History Asthma Hiyfever Acne Eczema Hives
TABLE DEPARTMENT WORKED v FAHILY HISTORY OF ILLNESS
#236 (n-44)
# %yes
236/237 (n-56)
tm
p -value
9 20.45 8 18.18 17 38.64 3 6.82 5 11.36
17 30.36 16 28.57 24 42.86 3 5.36 3 5.36
0.2624 0.2272 0.6701 0.7601 0.2718
TABLE DEPARTMENT WORKED v PERSONAL MEDICAL HISTORY
#236 (n*44)
i t Yes
Personal Medical History Headaches High Blood Pressure Bronchitis Pneimonta Pleurisy Chest Pain Kidney Trouble Bladder Trouble Diabetes Thyroid Problems Stomach Ulcer C o litis liv e r Problems A rth ritis Teenage Acne Skin Bolls
26 59.09 11 25.00 7 15.91 - 6 13.64 4 9.09 10 22.73 3 6.82 7 15.91 1 2.27 1 2.27 6 13.64 4 9.09 2 4.55 10 22.73 21 47.73 17 38.64
#236/237 (n56)
i t Yes
P-value
29 51.79 12 21.43 16 28.57 14 25.00" 7 12.50 18 32.14 3 5.36 5 8.93 3 5.36 4 7.14 12 21.43 2 3.57 3 5.36 18 32.14 17 30.36 18 32.14
0.4661 0.6736 0.1353 0.1585 0.5885 0.2979 0.7601 0.2863 0.4346 0.2673 0.3140 0.2486 0.8533 0.2979 0.0757 0.4992
C236213
..
._
T A B L E ____
DEPARTMENT WORKED v_ PERSONAL MEDICAL HISTORY
#236
# t Ye
#236/237
# t Ys
p-valut __________
Poison Ivy/Oak H im Other Rash Skin Cancer Prostate Canter
17 38.64 6 13.64 19 43.16 2 4.55 1 2.27
17 30.36 B 14.29
25 44.64 0 0.00 0. 0.00
0.3856 0.9260 0.8838 0.1070 0.2569
Vital Signs
TABLE ____ DEPARTMENT WORKED v VITAL SIGNS
#236 X . .(n )
#236/237 X - s.e.(n )
p-value
Quetelet Index (Helght/Melght x 100) S y sto lic BP D iasto lic BP Pulse Respiration Height Height Temperature
36.26 ~ 0.83(44)
123.70 t 2.71(44) 75.66 t 1.63(44) 77.75 t 1.61(44) 19.86 t 0.80(43} 70.41 t 0.47(44)
198.80 - 4.97(44)
97.76 - 0.09(42)
38.80 t 0.88(56)
0.0423
120.7 - 1.99(56) 72.50 - 1.38(56) 73.75 - 1.58(56) 18.85 0.45(54)
69.34 - 0.31(56) 184.73 - 5.08(56)' 97.90 - 0.09(53)
0.3647 0.1398 - 0.0835 0.2523 0.0512 0.0547 0.2921
TABLE ____ DEPARTMENT WORKED v DERMATOLOGIC FINDINGS
Dtraatoloolc Flndlnc* Chloracne
#236 <-44) im
#236/237 (n*56) L 2J2L
' 20 45.45 22 39.29
p-value
0.5350
Ja s . Coaedonal Cystic Pustular
Severity Mild Moderate
Locations
Temporal Forehead Malar Cheeks O c cip ita l Neck Trunk Shoulders
Genitalia
20 22 95 10 14 15 67 11 11 43 11 15 54 00 11 30 21 10
History only, Chloracne
10
13
-C23629
, TABLE ____ KPAKTKN TS WORKED DERMATOLOGICAL FINDINGS
Dermatol oq1cal' Findings'
#236 (n44)
rye*
Actinic Elastosis
5 11.36.
Severity
H1Id Moderate Severe
3 2 0
Where
Face Meek
5 2
Both Chloracne
t Actinic Elastosis
3 6.82
Malar Hirsutism
4 9.09
History Acne Vulgaris
20 45.45
Acne Vulgaris,
8 16.18
Severity Mild Moderate
7 1
F o llic u litis
4 9.09
A ctinic Keratoses
1 2.27
Basal Cell Epithelioma
0 0.00
Squamous Cell Epithelioma D 0.00
Seborrheic Dermatitis
2 4.55
Oermatophytosis
Hands Feet Nalls
Other
1
12 3 5
Psoriasis
0 0.00
Atopic Dermatitis
0 0.00
#236/237 (n*56)
i %Yes
7 12.50
3 2 2
5 3
1 1.79 1 1.79 22 39.29 12 21.43
11 1 6 10.71 2 3.57 0 0.00 0 0.00 7 12.50
0 18 3
7 0 0.00 1 1.79
p-value 0.8622
0.2024 0.0961 0.5350
0.7882 0.7055
-- ---- -
0.1677
0.3730
C2-363U
TABLE DEPARTMENTS WORKED v DERMATOLOGICAL FINDINGS
Dermatological Findings
Poikiloderma Face Neck Chest Other
#236 (n*44)
L 2
#236/237 (n-56) # Yes
00 01 00 01
C23631
. . table ___
DEPARTMENTS WORKED v DERMATOLOGICAL FINDINGS
Dermatological Findings
Dermatofibroma Lipoma Pigmented Nev1 Rosacea/Rhlnophyma Lichen Simplex Chronicus Alopecia Other Than
Pattem Baldness Neurofibroma Leukoderma Petechiae Ecchymoses Dupuytren's Contracture Junctional Nevi Lymphadenopathy Livedo R eticularis Xerosis Pilonidal Cyst O titis Externa Mild Chronic Dermatitis Xanthelasma Seborrheic Keratoses
#236 (n-44)
%Yes
0 0.00 1 2.27 2 ' 4.55 2 4.55 I 2.27 0 0.00
0 0.00 0 0.00 0 0.00 0 0.00 0 0.00 1 2.27 1 2.27 2 4.55 0 0.00 1 2.27 1 2.27 0 0.00 1 2.27
#236/237 (n*56)
%Yes
p-value
1 1.79 3 5.36 5 8.93 3 5.36 2 3.57 0 0.00
0.3730 0.4346 0.3938 0.8533 0.7055
0 0.00 0 0.00 1 1.79 1 1.79 1 1.79 1 1.79 1 1.79 2 3.57 0 0.00 1 1.79 0 0.00 1 1.79 7 12.50
-------0.3730 0.3730 0.3730 0.8629 0.8629 0.8051
0.8629 0.2569 0.3730 0.0613
C26632
TABLE ____ DEPARINTS WORKED v CLINICAL LABORATORY FINDINGS
#236 lii.e .( n )
#236/237 X i s.e.(n )
p-value
Sodtun Magneslun Potassium Chloride Caltftsn Phosphorous Iron BUN Creatinine BUN/Creat1n1ne Uric Acid 61ucose Total Protein
139.16 t 0.42(44}
2.02 - 0.04(44) 4.45 - 0.06(44} 103.42 - 0.60(43) 9.72 i 0.06(44)
2.B2 - 0.06(44) 107.68 - 4.19(44) 14.43 - 0.51(44)
1.33 i 0.03(44)
11.26 - 0.52(44) 6.14 - 0.20(44) 99.91 - 4.17(44) 7.79 - 0.07(44)
139.04 - 0.31(56)
2.01 t 0.02(56)
4.54 i 0.05(56} 103.68 - 0.41(56)
9.79 - 0.05(56) 2.85 - 0.05(56)
112.29 i 5.41(56) 15.43 - 0.58(56) 1.29 - 0.03(56) 12.27 i 0.51(56)
6.26 - 0.21(56) 95.38 - 1.69(56)
7.59 i 0.07(56)
0.8102 0.7828 0.2298 0.7122 0.3340 0.6701 0.5207 0.2144 0.3721 0.1744 0.6959 0.2780 0.0504
C26633
TABLE ___
DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
#236 X - s..(n )
#236/237 7 * s.c.(n )
p-value
AI burin Globulin Albun1n/GIobu11n Total Bilirubin Direct Bilirubin SGOT SGPT GGTP Alkaline
Phosphatase LDH
4.47 - 0.06(44) , 3.32 - 0.08(44) 1.39 i 0.04(44) 0.71 - 0.05(44)
0.21 - 0.02(44)
33.43 - 2.21(44) 42.14 - 2.41(44) 23.33 - 2.60(43)
30.00 - 1.21(44)
186.36 - 5.38(44)
4.44 > 0.04(56) 3.15 - 0.06(56) 1.43 - 0.03(56) 0.68 - 0.04(56) 0 .1 8 -0 .0 1 ( 5 6 ) 31.77 3.31(56) 44.41 - 5.22(56) 2 0 .IB - 2.25(56}
32.02 - 1.05(56)
175.55 - 3.55(56)
0{6762 0.0814 0.3716 0.6770 0.2831 0.6940 0.7178 0.3619 0.2096
0.0858
C2S634-
i
WBC , RBC HGB HCT MCV MCH HCHC
T A B L E ____
'"
DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
#236
i - i.e .( n )
6.70 - 0.27(42)
5.22 - 0.09(42) 15.94 - 0.19(42) 48.32 - 0.63(42) 92.83 - 0.71(42) 30.65 0.29(42)
33.01 - 0.13(42)
#236/237
J i s.e.(n)
7.25 - 0.25(56) 5.08 - 0.04(56)
15.61 t 0.15(56)
47.39 - 0.42(56)
93.36 - 0.63(56)
30.75 - 0.23(56) 32.93 - n .11(56)
p-value
0.1430 0.1193 0.1727 0.2087 0.5732 0.7919 0.6454
TABLE ____ DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
Polys (X) Lymphocytes (X) Monocytes (X) Eosinophils (X) Basophils (X)
236
X - s.e.(n )
59.83 - 1.17(42) 30.02 - 1.07(42)
7.13 t 0.33(42)
2.33 - 0.21(42) 0.70 t 0.09(42)
#236/237
Y - s.e.(n )
58.50 - 1.08(56) 31.21 - 1.03(56) 7.28 - 0.29(56) 2.27 - 0.16(56) 0.74 - 0.05(56)
P-value
0.4114 0.4310 0.7356' 0.8281 0.6106
C23S3 6
T A B L E _____ DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
Poly (Abs) Lymph (Abs) Mono (Abs) Eos (Abs) Baso (Abs)
#236 Y - s.e.(n)
#236/237 Y s.e.(n)
p-value
4076.64 - 228.34(42) 1966.45 - 60.71(42) 462.93 - 22.49(42)
151.45 - 14.30(42) 45.10 - 5.81(42)
4313.23 - 202.36(56) 2195.43 - 77.70(56)
523.64 - 24.97(56)
163.43 - 12.49(56) 52.59 - 3.51(56)
0.4415
0.0469 0.0843 0.5301 0.2489
BLOOD REFERENCE _RANGE W H S ------
TABLE ____ DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
236 .,.(,,)
236/237 s.e.(n )
P-value
Total Lipids (gm/dL) Cholesterol (ng/dL) Triglyceride (mg/dl)
Total Cholesterol (ng/dL)
C-HDL (ng/dL) C-LDL (ng/dL) C-VLDL (ng/dL)
0.70 - 0.03(43)
245.80 - 8.09(44) 186.73 - 14.11(44)
242.19 - 7.96(43)
47.72 2.68(43)
157.49 * 6.85(43) 37.73 - 5.72(43)
0.65 - 0.02(56} 234.93 - 6.34(56) 179.98 - 12.20(56) 231.43 - 5.69(56)
45.93 - 2.48(56) 155.18 - 5.78(56)
30.93 - 2.29(56)
0*1853 0.2856 0.7177 0.2617
0.6269 0.7962 0.2273
C ^ 6 `3 8
-
PH ,1 Specific Grevlty
TABLEDEPARTMENTS WORKED v. CLINICAL LABORATORY FINDINGS
#236 X i s.i.(n )
#236/237 T - t.e .(n )
p -v ilu e
5.28 * 0.08(43) 1.0224 - 0.0009(43)
5.29 i 0.07(55) 1.0235 - 0.0008(55)
0.9112 0.3746
C23639
TABLE ____ DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
BLOOD REFERENCE
RANGE UNITS
Sodltxn (rmo 1/L) 134.00 - 146.00
Magnesium (meg/L) < 1 .6 0 1 .6 0 -2 .2 0 >2,20
Potassium (rmo 1/L)
3.50 - 5.50 > 5 .5 0
Chloride (mmo 1/L)
< 96.00
96.00 - 110.00 >110.00
256
%Yes
236/237
i %Yes
D-value
44 100.00
0 0.00 37 84.09 7 15.91
43 97.73 1 2.27
0 0.00 42 97.67
1 2.33
56 100.00
, -- T-
2 3.57 48 85.71
6 10.71
0.3516
56 100.00 0 0.00
0.2569
2 3.57 54 96.43
0 0.00
0.2415
Iron (ug/dL) < 4 5 .0 0 45.00 - 200.00 > 200.00
Calcium ma/dL) < 8.80 6.80 - 10.80
Phosphorus (mg/dL) 2.00 - 4.70
BUN (ig/dL) < 6 .0 0 6.00 - 25.00 > 2 5 .0 0
Creatinine (mg/dL) 0.50 - 1.70
0 0.00 44 100.00 0 0.00
1 2.27 43 97.73
44 100.00
1 2.27 43 97.73
0 0.00
44 100.00
1 1.79 53 94.64 2 3.57
0.2967
0 0.00 56 100.00
0.2569
56 100.00 ---- -
0 0.00 53 94.64
3 5.36
'
0.1609
56 100.00
C23640
TABLE
DEPARTMENTS WORKED v, CLINICAL LABORATORY FINDINGS
BLOOD REFERENCE RANGE UNITS
BUN/Creat1n1ne Ratio 3.57 - 25.45
Uric Acid (mg/dL) 2.50 - 8.50 ...
> 8.50
Glucose (mq/dL)
65.00 - 130. oo
^130.00
Total Protein (qm/dl) 6.60 - 8.90
#236
# X Yes
##236/%23Y7es
p-value
44 100.00
42 95.45 2 4.55
42 95.45 2 4.55
44 100.00
56 100.00
50 89.29 6 10.71
0.2590
55 98.21 1 1.79
0.4219
56 100.00
______
C26641
table'___
DEPARTMENTS WORKED v_ CLINICAL LABORATORY FINDINGS
BLOOD REFERENCE RANGE UNITS
#236
# %Yes
Albumin (gm/dl)
*3.60
3.60 - 5.20 * 5 .2 0
1 2.27 42 95.45
1 2.27
Globulin (gm/dl) 1.90 - 3.70
^3.70 .
36 81.82 8 18.18
Albumin/Globulin Ratio 0.46 - 2.63
44 100.00
Total B iliru b in (mg/dL)
0.10 - 1.70
*1 .7 0
43 97.73 1 2.27
D irect B iliru b in (mg/dL)
0.00 - 0.30 > 0 .3 0
41 93.18 3 6.82
Transaminase. SGO (IU/L)
1.00 - 50.00 * 5 0 .0 0
40 90.91 4 9.09
Transaminase. SGP (IJJ/L)
1.00 - 70.00 >70.00
40 90.91 4 9.09
G-glutamyl Transpeptidase (U/L)
1.00 - 70.00 * 7 0 .0 0
42 97.67 1 2.33
A lkaline Phosphatase {lU / lJ
10.00 - 50.00
*50.00
43 97.73 1 2.27
LDH (IU/L)
t
90.00 - 250.00 t 250.00
42 95.45 2 4.55
#236/237
# %Yes
p-value
0 0.00 56 100.00 0 0.00
0.2729
50 89.29 6 10.71
0.2854
56 100.00
55 98.21
1 1.79
0.8629
52 92.86 4 7.14
0.9496
52 92.86 4 7.14
0.7215
52 92.86 4 7.14
0.7215
55 98.21 1 1.79
0.8499
55 98.21 1 1.79
56 100.00 0 0.00
0.1070
C2642
TABLE ____ DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
BLOOD REFERENCE RANGE UNITS
RBC (m ill Ions/cu.mm.) * 4 .6 4.6 - 6.2 76.2
Hemoglobin (gm/dL) *14.0 14.0 - 18.00 >08.00
Hematocrit (percent) <42.00 42.00 - 64.00 >54.00
HCV (cu.u) 80.00
80.00 - 100.00 >100.00
MCH * 26.00 26.00 - 33.00
> 33.00
HCHC (percent) * 31.00 31.00 - 36.00
#236
%Yes
1236/237
i %Yes
D-value
2 4.76 39 92.85
1 2.38
0 0.00 39 92.86
3 7.14
0 0.00 41 97.62
1 2.38
0 0.00 41 97.62 1 2.38
1 2.38 36 85.71 5 11.90
1 2.38 41 97.62
3 5.36 53 94.64 0 0.00
0.5071
3 5.36 53 94.64
0 0.00
0.0438
3 5.36 52 92.86
1 1.79
0.3090
1 1.79 51 91.07 4 7.14
0.3817
1 1.79 52 92.86
3 5.36
0.4R73.
1 1.79 55 98.21
0.8366
C2361J
TABLE ____ DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
BLOOD REFERENCE RANGE UNITS
##2%36Yes
CSC
WBC (thousand/cu.nro.)
4.00 - 11.60 >11.60
41 97.62 1 2.38
D ifferen tial Polys (percent!
**42.0 42.0 - 81.0 r-81.0
0 0.00 42 100.00
0 0.00
Lymphocytes (percent) ' 10.0 - 47.0
*47.0
42 100.00 0 0.00
Monocytes fpercent1
0.0 - 10.0 rlO .O
38 90.48 4 9.52
Eosinophils (percent) 0.0 - 8.0
42 100.00
Basophils (percent) 0.0 - 2.0
rZ. 0
41 97.62 1 2.38
#236/237
X Yes
D-value
54 96.43 2 3.57
0.7349
2 3.57 54 96.43
0 0.00
0.2159
54 96.43 2 3.57
0.2159
51 91.07 5 8.93
0.9196
56 100.00
--
56 100.00 0 0.00
0.2458
c 2 3 644
TABLE ____ DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
BLOOD REFERENCE RAN6E WITS
* K36 # * Yes
CBC Differential Absolute Values (cel Is/cu.cm .)
Neutrophils 1650 - 8330 >8330
Lymphocytes <1049 1049 - 3581 >3581
Monocytes 61 * 929 >929
Eosinophils <40 40 - 423
Basophils <10 10 - 148 >148
41 97.62 1 2.38
1 2.38 41 97.62 0 0.00
42 100.00 0 0.00
3 7.14 39 92.86
2 4.76 39 92.86
1 2.38
#236/237 i Yes
p-value
55 98.21 1 1.79
0.8366
0 0.00 54 96.43 2 3.57
0.2421
55 98.21 1 1.79
0.3840
2 3.57 54 96.43
0.4265
1 1.79 55 98.21
0 0.00
0.3500
C26645
I
TABLE DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
BLOOD REFERENCE RANGE UNITS
#236 # X Tes
#236/237
# %Yes
p-valut
Total H o ld s (gm/dL) 0.30 - 1.00 > 1 .0 0
Cholesterol (mg/dL) ^ 125 125 - 300 ^300
Triglyceride (mg/dL) 50 - 200
y 200
Total Cholesterol (mg/dL) -*125 125 - 300
y 300
C-HDL (mg/dL) *30 3 0 -7 5
y 75
C-LDL (mg/dL) *60 60 - 185 >085
C-VLDL (mg/dL) 0.0 - 40.0
y 40.0
41 95.35 2 4.65
1 2.27 36 81.82
7 15.91
30 68.18 14 31.82
1 2.33 36 83.72 6 13.95
7 16.28 34 79.07 2 4.65
1 2.33 30 69.77 12 27.91
31 72.09 12 27.91
55 98.21 1 1.79
0.4097
0 0.00 46 82.14 10 17.86
0.5148
39 69.64 17 30.36
0.8754
0 0.00 52 92.86
4 7.14
0.2661
11 19.64 42 75.00
3 5.36
0.8923
0 0.00 44 78.57 12 21.43
0.3724
46 82.14 10 17.86
0.2332
C266-4
TABLE DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
Urinalysis
Appearance Clear
Sped f 1c 6rav1ty 1.008 - 1.035
Acetone Negative 1+
Albumin Negative
Clucose Negative 2+
Blood Negative
WBC Negative 0 -2 2 -5 5-10 '
RBC Negative 0 -2
Casts Negative
Bacteria None Slight Koderate
#236
# %Yes
#236/237
%Yes
p-value
43 100.00
43 100.00
43 100.00 0 0.00
43 100.00
42 97.67 1 2.33
43 100.00
34 79.07 5 11.63 2 4.65 2 4.65
42 97.67 1 2.33
43 100.00
39 90.70 3 6.98 1 2.33
55 100.00
55 100.00
--
54 98.18 1 1.82
0.3741
55 100.00
...
53 . 96.36 2 3.64
0.708
55 1 0 0 .0 0
40 72.73 6 10.91 9 16.36 0 0.00
55 100.00 0 0.00
0.2556
55 100.00
48 87.27 7 12.73 0 0.00
0.3512
" \*
U rtn ilv it
TABLE
DEPARTMENTS WORKED v CLINICAL LABORATORY FINDINGS
236 ll
236/237 Li
C ry sU lt
Mont Uric Acid Caldun Oxilate
Ytast Negative
H .5 6 7
42 97.67 0 0.00 1 2.33
64 98.18 0 0.00 1 1.82
0.6601
43 100.00 65 100.00
32 74.42 10 23.26 1 2.33
41 74.55 12 21.82 2 3.64
0.B242
C28648
TABLE ____
262/268 EXPOSURE v DEMOGRAPHIC INFORMATION EVER IN DEPARTMENT 262 OR 268?
wo
X t *..(n)
_ Tet
X1 t.c.(n)
fr-value
Age
43.09 t 1.36(76)
47.5B 1 1.46(24)
0.0276
Education High School High School Graduate Sone College College Graduate*
%
11 14.47
35 46.05
22 28.95
8 10.53
X
4 16.67 15 62.50
5 20.83 0 0.00
0.25 p* 0.50
i
C2S70I
TABLE____ 262/268 EXPOSURE v OTHER DEPARTMENT WORKED
EVER IN DEPARTMENT 262 OR 268?
Ever in 237?
NO n=76 #%
47 61.84
YES
n=24 #%
p-value
9 37.50 0.0579
C2S70
TABLE ____ 262/268 EXPOSURE v PREVIOUS EMPLOYMENT EXPOSURES
EVER IN DEPARTMENT 262 OR 268?
PREVIOUS EMPLOYMENT EXPOSURES 1
Mechanical Work Farming Dust Solvents Cutting O ils Weid1ng/$oldering Fumes F e r tiliz e r Weed K ille r Asbestos Animal Feed Radiation Rubber Additives
No (n-76)
4%
27 3S.53 2 2.63 30 39.47 33 43.42 26 34.21 22 28.95 10 13.16 11 14.47 2 2.63 2 2.63 1 1.32 1 1.32
res (n*24)
4%
5 20.83 0 0.00 14 58.33 ^ 6 25.00 2 8.33 6 25.00 2 8.33
0 0.00 1 4.17 1 4.17 1 4.17 0 0.00
p-value
0.2163 1.0000 0.1563 0.1500 0.0175 0.7987 0.7255 0.0615 0.5652 0.5652 0.4242 1.0000
G2G70
TABLE ____ 262/268 EXPOSURE v TOBACCO AND ALCOHOL USE
EVER IN DEPARTMENT 262 OR 268?
Alcohol Status
Never Former Present
No
%Yes
5 6.58 B 10.53 63 82.89
Yes
%Yes
2 8.33 3 12.50 19 79.17
p-value 0.9159
Smoklnq Status Never Former Present (Unknown)
Pack Years
18 24.00 17 22.67 40 53.33
1
4 *7
12 1
17.39 30.43 52117
j t s.e.(n )
X s.e.(n )
17.74 - 2.69(69)
23.67 i 5.37(21)
0.6768
'
0.3021
C270'
TABLE ____; 262/268 EXPOSURE v FAMILY HISTORY OF ILLNESS
EVER IN DEPARTMENT 262 OR 268?
Family History
Asthma Hayfever Acne Eczema Hives
No (n*76)
4 * Yes
18 23.68 20 26.32
31 40.79
3 3.95
6 7.B9
Yes (n-24)
I %Yes
8 33.33 4 16.67
10 41.67
3 12.50
2 8.33
P-value *
0.4245 0.4190 1.0000 0.1476 1.0000
by Fisher's Exact test
C2Q70
TABLE ____ 262/26B EXPOSURE v PERSONAL MEDICAL HISTORY
EVER IN DEPARTCNT 262 OR 268?
Personal Medical History*
No
(n76)
%Yes
Yes
(n24)
%Yes
p-value **
Headaches High Blood Pressure Bronchitis Pneumonia Pleurisy Chest Pain Kidney Trouble Bladder Trouble Diabetes Thyroid Problems Stomach Ulcer C o litis Liver Problems A rth ritis Teenage Acne Skin Bolls Poison Ivy/Oak Hives Other Rash , Nos Skin Cancer Prostate Cancer *Inc1udes unconfirmed **by Fisher's Exact test
42 55.26 13 54.17
1.000
14 18.42 9 37.50
0.0920
16 21.05 7 29.17
0.4155
16 21.05 4 16.67
0.7747
8 10.53 3 12.50
0.7224
21 27.63 7 29.17
1.0000
3 3.95 3 12.50
0.1476
9 11.84 3 12.50
1.0000
1 1.32 3 12.50
0.0419
3 3.95 2 8.33
0.5910
15 19.74 3 12.50
0.5502
4 5.26 2 8.33
0.6280
2 2.63 3 12.50
0.0879
18 23.68 10 41.67
0.1175
30 39.47 8 33.33
0.6375
27 35.53 8 33.33
1.0000
28 36.84 6 25.00
0.3320
11 14.47 3 12.50 1.0000
31 40.79 13 54.17
0.3457
1 1.32 1 4.17
0.4242
1 1.32 0 0.00
1.0000
C2370
t a b l e ____ 262/268 EXPOSURE v_ VITAL SIGNS
I
EVER IN DEPARTMENT 262 OR 268?
i Vital Signs 1j
i
j Quetelet Index (Height/Weight
j x 100)
S y sto lic BP i j D ia sto lic BP
j Pulse
! Respiration
| Height i
Weight
Temperature
lii
_____No X i s.e.(n ) 37.99 1 0.72(76)
122.00 t 1.86(76) 73.58 t 1.29(76) 75.17 t 1.34(76) 19.40 1 0.54(73) 69.79 t 0.31(76) 189.28 t 4.17(76) 97.87 t 0.07(74)
Yes X i s.e.(n)
36.69 t 1.25(24)
p-value 0.3733
122.13 1 3.43(24)
74.88 1 1.71(24) 76.58 1 2.21(24) 19.00 1 0.67(24)
69.88 t 0.60(24)
196.13 1 7.51(24) 97.70 1 0.15(21)
0.9740 0.6040
'o .m s
0.6962 0.8943 0.4244 0.2663
C26707
I
TABLE ____ 262/268 EXPOSURE v CHLORACNE
EVER IN DEPARTMENT 262 OR 268?
Chloracne
Comednal Cystic Pustular
Severity
Mild Moderate
Site
Temporal Forehead Malar Cheeks Occipital Neck Trunk Shoulders Genitalia
Oermatologlst History o f Chloracne
* by Fisher's Exact Test
No (n-76)
Ll
33 43.42
33 10 1
Yes (n-24) 1 9 37.50
9 4 0
p-value 0.6436
23 10
1 16 7
22 7 0 2 2 1 i
6 3
6 0 4 2 0 0 1 2 0
49 64.47 16 66.67 1.0000
C25708
t a bl e ____ 262/268 EXPOSURE v DERMATOLOGIC FINDINGS
EVER IN DEPARTMENT 262 OR 268?
Dermatologic Findings
No (n76)
Actinic Elastosis
Severity
Mild Moderate Severe
Where Face Week
Both Chloracne and Actinic Elastosis
9 11.64
4 3 2
7 5 3 3.95
Malar Hirsutism History Acne Vulgaris
Acne Vulgaris Severity
Mild Moderate
F o llic u litis Actinic Keratoses Basal Cell Epithelioma Squamous C ell Epithelioma Seborrheic Dermatitis Dermatophytosis
Hands Feet Nails Other
Psoriasis Atopic Dermatitis Poikiloderma
Face Neck Chest Other
Dermatofibroma Lipoma Pigmented Nevi Rosa/cea/Rhlnophyma
2 2.63 34 44.74 18 23.68
16 2 9 11.84 2 2.63 0 0.00 0 0.00 6 7.89
1 1.32 23 30.26 3 3.95 9 11.84 0 0.00 1 1.32
0 0.00 0 0.00 0 0.00 1 1.32 0 0.00 4 5.26 3 3.95 3 3.95
Yes (n24)
3 12.50
2 1 0
3 0 1 4.17
3 12.50 8 33.33 2 8.33
2 0 1 4.17 1 4.17 0 0.00 0 0.00 3 12.50
0 0.00 7 29.17 3 12.50 3 12.50 0 0.00 0 0.00
*
1 4.17 0 0.00 0 0.00 0 0.00 1 4.17 0 0.00 4 16.67 2 8.33
p-value
1.0000
1.0000
0.0879 0.3537 0.1445
0.4437 0.5652 -- 0.4449
1.0000 1.0000 0.1476 1.0000 ....-- 1.0000
0.2400
1.0000 0.2400 0.S697 0.0549 0.5910
C2570tf
TABLE
262/268 EXPOSURE v_DERMATOLOGIC FINDINGS
Dermatoloqic Findings
EVER IN DEPARTMENT 262 OR 268?
No Yes # fifes # T 7 e s
Lichen Simplex Chronicus
Alopecia Other than Pattern Baldness
Neurofibroma
Leukoderma
Petechiae Ecchymoses
Dupuytren's Contracture
Junctional Nevi
Lymphadenopathy .
Livedo Reticularis
Xerosis
i
Pilonidal Cyst .
Otitis Externa
Mild Chronic Dermatitis
Xanthelasma
Seborrheic Keratoses
2 2.63 0 0.00 0 0.00 0 0.00 0 0.00 1 1.32 1 1.32 2 2.63 2 2.63 4 5.26 0 0.00 1 1.32 1 1.32 1 1.32 5 6.58
1 4.17 0 0.00 0 0.00 0 0.00 0 0.00 0 0.00 0 0.00 0 0.00 0 0.00 0 0.00 0 0.00 1 4.17 0 0.00 0 0.00 3 12.50
p-value
0.5652
0.2400 1.0000 1.0000 1.0000 1.0000 0.5697
0.4242 1.0000 1.0000 0.3938
C2-371
TABLE ____
262/268 EXPOSURE v CLINICAL LABORATORY FINDINGS
EVER IN DEPARTTENT 26? OR 268?
1Sod1m (age Adjusted)
1Magnesium | (age adjusted)
1Potassium 1(age adjusted)
!Chloride
.
, (age adjusted)
'Calcium |(age adjusted) !Phosphorous I(age adjusted)
Iron ! (age adjusted) iBUN ; (age adjusted) 1Creatinine : (age adjusted) ! BUN/Creat1n1ne : (age adjusted) 'Uric Acid 1 (age adjusted)
Glucose (age adjusted) ; Total Protein , (age adjusted) 1 Albumin (age adjusted) Globulin , (age adjusted) . Albumlh/GTobulln (age adjusted) Total Bilirubin (age adjusted) Direct Bilirubin (age adjusted)
No X Z s.*.(n)
139.11 t 0.30(76) 139.13 I 0.29
2.02 '0.02(76) 2.02 * 0.02
Yet X Z *..(n)
139.04 Z 0.49(24) 138.98 t 0.53
'1.99 Z 0.04(24) 1.98 Z 0.04
4.49 j 0^05(76) 4.50 Z 0.05 103.95 0.38(76) 103.95 Z 0.39
4.52 Z 0.09(24) 4.51 I 0.08 102.30 + 0.77(23) 102.28 * 0.72
9.76 * 0.04(76) 9.76 Z 0.04
9.75 0.07(24) 9.75 Z 0.08
2.84 0.04(76) 2.84 Z 0.04
2.81 Z 0.06(24) 2.82 I 0.08
111.51 Z 4.31(76) 110.54 Z 3.94
106.29 Z 5.65(24) 109.37 Z 7.07
14.78 0.45(76) 14.81 Z 0.46
15.67 Z 0.84(24) 15.57 Z 0.82
1.31 Z 0.03(76) 1.31 Z 0.02
1.28 Z 0.03(24) 1.27 f 0.04
11.60 * 0.41(76) 11.62 Z 0.43
12.53 Z 0.80(24) 12.47 Z 0.76
6.19 2 0.16(76) 6.20 Z 0.17
6.27 Z 0.31(24) 6.?2 Z 0.30
95.33 Z 1.37(76) 95.80 t 2.30
103.83 Z 7.41(24) 102.35 I 4.13
7.69 t 0.06(76) 7.69 Z 0.06
7.63 Z 0.10(24) 7.64 f 0.11
4.46 * 0.04(76)
4.43 Z 0.04(24)
. 4.45 I 0.04
. . 4.46 I 0.07
3.24 Z 0.06(76) 3.24 * 0.06
3.20 ? 0.08(24) 3.19 Z 0.10
1.42 * 0.03(76) 1.41 Z 0.03
1.41 Z 0.03(24) 1.42 I 0.05
0.70 t 0.04(76) 0.70 ! 0.04
0.67 0.04(24) 0.67 : 0.06
0.19 1 0.01(76) 0.19 Z 0.01
0.19 Z 0.01(24) 0.19 : 0.02
P-value
0.915? 0.8040 0.5469 0.3651
0.7865 0.9331 0.0448 0.0459
0.8360 0.9173 0.6749 0.8045 0.5309 0.8854 0.3408 0.4195 0.4348 0.3860 0.7875 0.3402 0.8168 0.9520 0.0785 0.1710 0.5842 0.7057 0.7601 0.9238 0.7324 0.6543 0.8824 0.9404 0.6088 0.6788 0.7191 0.8097
1
TABLE ______ EVER IN DEPARTMENT 262 or 268?
SGOT (ge adjusted) SGPT (age adjusted)-
SGTP (age adjusted)
No X t.e.(n )
33.12 2.68(76)
33.48 t 2.38 45.13 t 3.96(76)
45.58 i 3.55
22.27 2.05(75) 22.53 t 1.95
Alkaline Phosphatase (age adjusted) LDH (age adjusted)
31.74 t 0.92(76)
31.82 0.91
180.83 t 6.20(76) 180.72 t 3.63
Yes
X t S.e.(n)
30.54 t 1.84(24)
29.39 1 4.28
37.96 * 2.91(24) 36.54 t 6.37 19.29 t 2.90(24)
18.48 t 3.48
29.21 1.52(24)
28.94 1 1.63
178.67 4.49(24)
179.02 t 6.51
p-valuc
0.6000 0.4082 0.3256 0.2209 0.4565 0.3159
n.1758 0.1298 0.769a 0.8207?
TABLE ____ 262/268 EXPOSURE v CLINICAL LABORATORY FINDINGS
EVER IN DEPARTMENT 262 OR 268?
WBC '(age adjusted) RBC * (age adjusted) HGB (age adjusted) Ihct (age adjusted) MCV (age adjusted) iMCH (age adjusted) ,HCHC , (age adjusted)
No X - s.e.(n )
6.96 + 0.21(74) 7.00 t 0.21 5.13 0.06(74) 5.14 f 0.05 15.71 0.14(74) 15.72 1 0.14 47.72 0.44(74) 47.77 1 0.42 93.12 0.56(74) 93.18 1 0.54 30.68 t 0.22(74) 30.69 0.21 32.94 1 0.10(74) 32.92 0.10
Yes T s.e.(n)
7.20 0.37(24) 7.05 1 0.37 5.16 t 0.06(24)
515 0.09 15.B8 0.21(24) 15.84 0.25
48.02 * 0.58(24)
4 7 .B5 1 0.74 93.17 t 0.85(24) 93.00 0.96 30.79 0.29(24) 30.76 0.37
33.05 * 0.15(24)
33.09 0.17
p-value
0.5633 0.9050 0.8193 0.9328 0.5528 0.6712 0.7199 0.9222 -.0.9692 0.8730 0.7990 0.8581 0.5663 0.4174
C3371j
. TABLE ____ 262/268 EXPOSURE v_ CLINICAL LABORATORY FINDINGS
EVER IN DEPARTMENT 262 OR 268?
Poly (X) (age adjusted)
Lymphocytes (X) (age adjusted)
Monocytes (X) (age adjusted)
Eosinophils (X) (age adjusted)
Basophils (X) (age adjusted)
Ho y i s,e.(n )
58.51 t 0.94(74)
58.64 1 0.91 31.31 t 0.89(74) 31.18 t 0.85 7.30 t 0.25(74)
7.31 0.25 2.14 t 0.14(74)
2.13 l 0.15 0.74 1 0.06(74)
0.74 : 0.05
Tes y i s.e.(n )
60.80 t 1.42(24)
60.40 : 1.61 28.80 1.27(24) 29.20 1.50
6.95 t 0.46(24) 6.92 Z 0.44
2.78 1 0.27(24) 2.81 0.26
0.67 t 0.07(24) 0.67 : /0.09
p-yAlac.
0.2168 0.3486 0.1471 0.2565 0.4B28 t 0.4460 * 0.0310 , 0.0247/-'; 0.4922 1 0.5203
C2S714
. TABLE ____ 262/268 EXPOSURE v. CLINICAL LABORATORY FINDINGS
EVER IN DEPARTMENT 262 OR 268?
Poly (Abs) (age adjusted) L(yamgepha(dAjubsst)ed) H(aogneo a(Adbjus)sted) E(aogse(Aadbsju)sted) Baso (Abs) (age adjusted)
-
*0 x l s.e.(n)
4137.05 1 176.90(74) 4175.88 1 170.50
2119.23 X 67.00(74) 2125.28 Z 66.27
501.54 * 21.03(74) 504.88 Z 19.97
145.89 145.90
t!
10.37(74) 10.64
50.07 1 3.81(74) 50.28 I 3.73
Yes X t s.e.(n)
4442.42 + 290.32(24) 4322.71 Z 302.03 2029.67 * 109.98(24) 2011.00 Z 117.40 485.54 1 29.66(24) 475.25 Z 35.37 196.54 * 19.42(24) 196.52 Z 18.85
47.25 * , 5.84(24) 46.59 1 6.61
p-value
0.3878 0.6749 0.5034 0.4017 0.6948 0.4703 0.0194 0.0223 0.7073 0.6296
. TABLE ____
262/268 EXPOSURE CLINICAL LABORATORY FINDINGS
EVER IN DEPARTMENT 262 OR 268?
Total L1p1ds (gm/dL) (age adjusted) Cholesterol (mg/dL) (age adjusted) Triglyceride (mg/dL) (age adjusted) Total Cholesterol (mg/dL) (age adjusted) C-HDL (mg/dL) (age adjusted) C-LDL (mg/dL) (age adjusted) C-VLDL (mg/dL) (age adjusted)
No X s.e.(n )
0.67 t 0.02(75) 0.67 Z 0.02
239.09 t 6.20(76) 240.18 t 5. 7 1
186.28 t 10.79(76)
187.52 1. 10.57
235.11 236.09
t1
5.98(75) 5.40
47.08 Z 2.10(75) 4 6 .B6 Z 2.10
154.29 155.18
tt
5.41(75) 5.02
34.33 - 3.60(75) 34.82 Z 3.22
Yes
* * **(")
0.67 Z 0.03(24)
0 .6 6 z 0.04
241.67 Z 7.50(24)
238.23 Z 10.24
172.42 Z 17.51(24) 168.49 Z 18.96 239.21 Z 5.77(24) 236.14 Z 9.63 45.54 Z 3.66(24) 46.23 Z 3.74 162.08 t 6.63(24) 159.31 Z 8.95 32.58 Z 2.87(24) ' 31.05 Z 5.75
p-value
0.9766 0.7281 0.8282 0.8692 0.5224 0.3857 0.7122 0.9963 0.^184 0.8845 0.4509 0.6902 0.7908 0.5702
C28710
. TABLE ____ 262/268 EXPOSURE v CLINICAL LABORATORY FINDINGS
EVER IN DEPARTMENT 262 OR 268?
(age adjusted)
sp ecific Gravity (age adjusted)
No X ..(n)
5.32 1 0.06(74} 5.32 * 0.06 1.0235 ? 0.0007(74) 1.0234 Z 0.0007
1
* t *.(")
5.17
5.19
1.0214 1.0216
+ +
0.05(24} 0.11
0.0013(24) 0.0013
P-viluc
0.1864 0.3103 0.1374 0.2139
4
(
rO o kj i 1 !ji
TABLE
262/268 EXPOSURE v CLINICAL LABORATORY FINDINGS
fI#lof*ordtnc fing Unit*
EVER IN DEPARTMENT 262 OR 268?
No i
Isi 1i
-valpc
5ed1um(wcVl) 4.00 - 46.00
Ugn*s1u(cs/L) 1.60 1.60 - 2.20 > 2.20
76 100.00 24 100.00 2 2.63 0 0.00 64 64.21 21 87.50 10 13.16 3 12.50
--
0.7186
f o t m 1utt( nol/ L )
3.60 - 5.50 > 5.SO
75 38.68 24 100.00 1 1.32 0 0.00
1 .0 0 0 0
Chloride(w n o V L )
< 36.00 6.00 - 110.00 > 110.00
ClIcfumfmg/ dL)
<3.80 8.80 * 10.80
2 2.63 0 0.00 73 36.05 23 100.00 1 1.32 0 -0 .0 0
1 1.32 0 0.00 75 98.68 24 200.00
0.6262
1 .0 0 0 0
f ho* phoni* ( tnq/ d L )
2.00 - 4.70
76 100.00 24 100.00
--
Iron ( ug/ d L ) < 45.00 45.00 - 200.00 > 200.00
1 1.32 0 0.00 73 6.05 24 100.00 2 2.63 0 0.00
0.6136
t U N ( * ig/ dL)
< (.00 6.00 - 25.00 >25.00
Crcittatneta/dL) 0.50 - 1.70
1 1.32 0 0.00 73 36.05 23 95.83 2 2.63 1 4.17 76 100.00 24 100.00
0.7949
8Uf/ C n i t < n1ne Ritto
3.57 - 25.46
Uric Ac1d(.g/dL) 2.50 - 8.50 > 8.50
76 100.00 24 100.00
760
27..1619
22 2
1.67 8.33
1 .0 0 0 0
C2S718
*by Fisher's Exact Test fo r 2x2 ta b le s; by chi-square te st fo r 3x2 tab les.
TABLE ____ 262/268 EXPOSURE v CLINICAL LABORATORY"FINDINGS
Blood Reference Range U nlit
EVER IN DEPARTMENT 262 OR 268?
Ho #s
Yes
1%
p-value *
S1ucose(mg/dL) 6$.00 - 130-00 > 130,00
l Total Prote1n(qm/dL) 6.60 - 8.90
A1butnin(qm/dL) < 3.60 3.60 - 5.20 > 5.20
S1obu11n(qtn/dL) 1.90 - 3,70 > 3.70
41hum1n/Globu11n Ratio 0.46 - 2.63
75 98.68 22 91.67 1 1.32 2 6.33 76 100.00 24 100.00 1 1.32 0 0.00 74 97.37 24 100.00 1 1.32 0 , 0.00
0.1422 0.7245
64 84.21 12 15.79
76 100.00
22 91.67 2 8.33
0.5081
24 " 100.00-- r
c
r
I Total BiTirublnfmq/dL) 0.10 - 1.70
' > 1.70 * Direct Bi11rub1n(mg/dL)
74 97.37 24 100.00 2 2.63 0 0.00
0.00 - 0.30 >0.30
70 92.11 23 95.83 6 7.69 1 4.17
Transaminase SG0(1U/L) 1.00 - 50.00 >50.00
70 92.11 22 91.67 6 7.89 2 8.33
Transaminase. S6P(IU/1)
1.00 - 70.00 > 70.00
69 90.79 23 95.83 7 9.21 1 4.17
6-glutamyl Trans&ept1dase(U/L^
1.00 - 70.00 > 70.00
74 98.67 23 95.83 1 1.33 1 4.17
A d elin e Phosphatase(IU/l)
10.00 - 50.00 > 50.00 i-PH(lU/L)
74 97.37 24 100.00 2 2.63 0 0.00
90.00 - 250.00
> 250.00
74 97.37 24 100.00 2 2.63 0 0.00
1.0000
1.0000
1.0000
0.6758
0.4280
1.0000 1.0000
C36719
* TABLE ____ 262/268 EXPOSURE v CLINICAL LABORATORY FINDINGS
EVER IN DEPARTMENT 262 OR 268?
Klood Reference Range Units
RBC(1111ons/cu . m . }
4<.64 .6- 6.2 >6.2
Hemogloblnfgm/dL) <14.0 14.0 - 18.00 >18.00
Hematocr1t (percent) <42.00 42.00 - 54.00 >54.00
KCVjcu.u) < 80.00 80.00 - 100.00 > 100.00
MCHfuua) <26.00 26.00 * 33.00 >33.00
HCHC(ercentJ <31.00 31.00 - 36.00
Ho
#%
Yes
#t
p-value *
4 5.41 1 4.17 69 93.24 23 95.83
1 1.35 0 0.00 2 2.70 1 4.17 69 93.24 23 95.83 3 4.05 0 0.00 2 2.70 1 4.17 70 94.59 23 95.83 2 2.70 0 0.00
0.8221 0.5733 0.6776
1 1.35 0 1 0.00 68 91.89 24 100.00
5 6.76 0 0.00
0.3547
2 2.70 0 0.00 66 89.19 22 91.67 6 8.11 2 8.33
0.7181
2 2.70 0 0.00 72 97.30 24 100.00
1.0000
* by Fisher's Exact Test fo r 2x2 tab les; by ch1-square te st fo r 3x2 tab les.
TABLE ____ 262/268 EXPOSURE v. CLINICAL LABORATORY FINDINGS
EVER IN DEPARTMENT 262 OR 268?
o CM
1 o om
Blood Reference Range Units
CBC WBC(tbousand/cu.wn.)
. 4>.0101.6-011.60
D iffe re n tia l Polys(percent) <42.0 42.0 - 61.0
Lymphocytes!percent) 10.0 47.0 >47.0 Monocytes!percent) 0.0 - 10.0 > 10.0 Eos1nophl1s ( percent) 0.0 - 8.0 Basophils(percent)
> 2.0
* by Fisher's Exact Test.
Ho
1%
Yes
#%
p-value
72 97.30 23 95.S3 2 2.70 1 4.17
1.0000
2 2.70 0 0.00 72 97.30 24 100.00
1.0000
72 97.30 24 100.00 2 2.70 0 / 0.00 69 93.24 20 83.33 5 6.76 4 .16.67
1.0000
.
0.2163
74 100.00 24 100.00
73 98.65 24 100.00' 1 1.35 0 0.00
l r0000
C2S721
. TABLE ____ 262/268 EXPOSURE v CLINICAL LABORATORY FINDINGS
EVER IN'DEPARTMENT 262 OR 268?
Blood Reference Range Units
No Yes
lit!
CBC
D iffe re n tia l Absolute Values(celIs/cu.am .)
Neutrophils
1650 - 8330 > 8330
72 2
97.30 2.70
24 100.00 0 0.00
Lymphocytes
< 1049 1049 - 35B1 > 3581
1 1.35 71 95.95 2 2.70
0 0.00 24 100.00 0 0.00
Monocytes 61 - 929 > 929
Eosinophils < 40 40 - 423
Basophils < 10 10 - 148 > 14B
73 98.65 24 100.00 1 1.35 0\ 0.00 5 6.76 0 0.00 69 93.24 24 _ 100.00 3 4.05 0 0.00 70 94.59 24 100.00 1 1.35 0 0.00
p-value *
1.0000 0.6054 1.0000 0.3299 0.5085
* by Fisher's Exact Test fo r 2x2 tab les; by chi-square te s t fo r 3x2 tab les.
|
TABLE ____ 262/268 EXPOSURE v. CLINICAL LABORATORY FINDINGS
EVER IN DEPARTMENT 262 OR 268?
Blood Reference Range Units
Total L1p1ds(qm/dL) 0.30 - 1.00 y1.00
Cbolesterolina/dL^ < 125 125 - 300 > 300
THglyceridefeg/dL) 50 - 200 > 200
Total Cholesterol(mg/dL) < 125 125 - 300 > 300
C-HDL(mg/dL) < 30 30 - 75 > 75
C-LDL(mg/dL) < 60 60 - 185 > 185
C-VLDL(mg/dL) 0.0 - 40.0 > 40
No
#%
Yes
4t
p-value *
72 96.00 24 100.00 3 4.00 0 0.00
1.0000
1 1.32 0 0.00
61 80.26 21 87.50
14 18.42
3 12.50
0.6675
51 67.11 18 75.00
25 32.89
6 25.00
0.6142
1 . 1.33 66 88.00
8 10.67
0 0.00 22 '91.67
2 8.33
0.8003
-
13 17.33
5 20.83
58 77.33 18 _ 75.00
4 5.33 1 4.17
0.9119
1 1.33 0 0.00 . 0.5010 54 72.00 20 83.33 20 26.67 4 16.67
60 80.00 17 70.83
15 20.00
7 29.17
0.4006
* by Fisher's Exact Test for 2x2 tables; by chi-square test for 3x2 tables.
C2G723
TABLE ____ 262/268 EXPOSURE v CLINICAL LABORATORY FINDINGS
EVER IN DEPARTMENT 262 OR 268?
Urinalysis
Appearance Clear
Specific Gravity 1.008 - 1.036
Acetone Negative 1+
Albumin Negative
Glucose Negative 2+
Blood Negative
WBC Negative 0 -2 2 -5 5-10
RBC Negative 0 -2
Casts Negative
Bacteria None Slight Moderate
No #%
Yes 4*
p-value *
74 100.00 24 100.00 .
74 100.00 24 100.00
--
74 100.00 23 95.83 0 0.00 1 4.17
0.2449
74 100.00 24 100.00
--
72 97.30 23 * 95.83
2 2.70
1 . 4.17
1.0000
74 100.00 24 100.00
--
53 71.62 21 87.50
9 12.16
2 8.33
10 13.51
1 4.17
2 2.70 0 0.00
0.10* p* 0.25
74 100.00 23 95.83 0 0.00 1 4.17
0.2449
74 100.00 24 100.00
66 69.19 21 87.50 7 9.46 3 12.50 1 1.35 0 0.00
0.7810
* by Fisher's Exact Test for 2x2 tables; by chi-square test for 3x2 and 4x2 tables.
s
TABLE ____ 262/268 EXPOSURE v CLINICAL LABORATORY FINDINGS
EVER IN DEPARTMENT 262 OR 268?
Blood Reference noe Units
^ .
Cr/stsls
UNornice Acid
C a ld i Oxalate
Tent Negative
PH 5 6 7
No
1
72 97.30 0 0.00 2 2.70
Yes
%
<
24 0
1000..0000
0 0.00
. 74 100.00 24 100.00
-valve *
1.0000
.f
--
53 71.62 20 83.33 18 24.32 4 " 16.67 3 4.05 0 0.00
0.4106
* by chi-square te s t .
c OiJ
\ TABLE
AGE AND EDUCATION
Age
Education
High School HIgh School Graduate Some College College Graduate +
r - f.c.(n )
44.17 - 1.10(100)
i%
15 15.00 50 50.00 27 27.00
8 8.00
Worked 1n #236 Worked 1n #237 Worked 1n #262
Worked in #268
TABLE DEPARTfCNTS WORKED
#%
100 100.00 56 56.00 19 19.00 10 10.00
TABLE ____ PREVIOUS EWLOYMENT EXPOSURES
Previous Employment Exposures
Mechanical Work Farming Dust Solvents Cutting 011s Weid1ng/Soldering Fianes F e r tiliz e r Weed K ille r Asbestos Animal Feed Radiation Rubber Additives
%
32 32.00 2 2.00 44 44.00 39 39.00 28 28.00 28 28.00 12 12.00 n 11.00 3 3.00 3 3.00 2 2.00 1 1.00
TABLE ____
TOBACCO AND ALCOHOL USE
Smoking Status Never
! Former Present (Unknown)
Al coho! Status Never Former Present
Pack Years*
Former Smokers Pack Years
Present Smokers Pack Years
# t Yes
22 22.45 24 24.49
252 53.06
7 n
171..0000
82 82.00
X - s.e.{n )*J
19.12
2.42(90)
15.77
- 3.31(22)
29.87
-3.69(46)
C2339G
TABLE FAMILY HISTORY OF ILLNESS
Family History
Asthma Hayfever Acne Eczema Hives
# t Yes
26 26.00 24 24.00 41 41.00
6 6.00 8 8.00
C23537
TABLE ____ ' PERSONAL MEDICAL HISTORY
Personal Medical History
Headaches High Blood Pressure (conflrmed)
Bronchitis
Pneumonia (confirmed)
Pleurisy (confirmed)
Chest Pain (confirmed)
Kidney Trouble (confirmed)
Bladder Trouble (confirmed)
Diabetes (confirmed)
Thyroid Problems (confirmed)
Stomach Ulcer (confirmed)
Colitis 1 (confirmed)
Liver Problems (confirmed)
Arthrl t1s
Teenage Acne (KD treated)
Skin Bolls (confirmed)
#
55
23 20
23
20 11
11 8
28 23
6 3
12 8
4 3
5 2
18 . 17
5 5
5 5
28
38 4
35 9
%Yes
55.00 23.00 23.00 20.00 11.00 28.00 6.00 12.00 4.00 5.00 18.00 6.00 5.00 26.00 38.00 35.00
Poison Ivy/Oak
Hives
Other Rash (confirmed)
Skin Cancer (confirmed)
Prostate Cancer (confirmed)
TABLE
X Yes
34 34.00 14 14.00 44 44.00 35 2 2.00 1 1 1.00 1
TABLE _ VITAL SIGNS
Vital Signs
Quetelet Index (Helght/Welght x 100) S y sto lic BP D ia sto lic BP Pulse Respiration Height Weight Temperature
X - s.e.(n) 37.68 - 0.62(100)
122.03 1 1.63(100) 73.89 i 1.06(100) 75.51 t 1.15(100) 19.30 - 0.44(97)
69.81 - 0.27(100)
190.92 - 3.64(100) 97.84 - 0.06(95)
C26600
Chloracne
Comdonal Cystic Pustular
Severity
HI 1d Moderate
Temporal Forehead Halar Cheeks Occipital Neck Trunk Shoulders Genitalia
TABLE ____
CHOLORACNE FINDINGS
#%
42 42.00 42 14
1
29 13
22' 7
26 9 0 2 3 3 1
C23601
TABLE ____ DERMATOLOGICAL FINDINGS
Dermatological Findings
Actinic Elastosis Severity
f Mild Moderate Severe
Where Face Neck Both Chloracne & Actinic Elastosis Dermatologist History Chloracne Malar Hirsutism History Acne Vulgaris Acne Vulgaris Severity Mild Moderate F o llic u litis Actinic keratoses Basal Cell Epithelioma Squamous C ell Epithelioma Seborrheic Dermatitis Dermatophyt o s i s Hands Feet Nails Other
# X Yes
12 12.00 6 4 2
10 5 4 4.00
65 65.00
5 5.00 42 42.00 20 20.00
18 2 10 10.00 3 3.00 0-- 0-- 9 9.00
1 1.00 30 , 30.00 6 6.00 12 12.00
C 26602
Dermatological Findings
Psoriasis Atopic Dermatitis Poikiloderma
Face Neck
Chest Other
TABLE
0
1 1.00
1 1.00
1 1.00
nu nu
_____
1 1.00
Dermatologic Findings
Dermatof1broma Lipoma Pigmented Nev1 Rosacea/Rhlnophyma Lichen Simplex Chronicus Alopecia Other Neurofibroma Leukoderma Petechlae Ecchymoses Dupuytren' s Contracture Ounctional Nevi Lymphadenopathy Livedo R eticularis Xerosi s _ Pilonidal Cyst O titis Externa Mild Chronic Dermatitis Xanthelasma Sebordieic Keratoses
TABLE
# 1 4 7 5 3 0 0 0 1 1 1 2 2 4 0 2 1 1 8
X Yes
1*00 4.00 7.00 5.00 3.00
1.00 1.00 1.00 2.00 2.00 4.00
2.00 1.00 1.00 8.00
TABLE
CLINICAL LABORATORY FINDINGS
Sodium Magnesium Potassium Chloride Calcium Phosphorous Iron
BUN
Creatinine
BUN/Creatinine
Uric Acid Glucose Total Protein Albumin
X - s.e.(n) 139.09 - 0.25(100)
2.01 - 0.02(100) 4.50 - 0.04(100)
103.57 t 0.35(99)
9.75 - 0.04(100) 2.84 - 0.04(100) 110.26 - 3:54(100)
14.99 t 0.40(100) 1.30 i 0.02(100)
11.83 i 0.37(100)
6.21 - 0.14(100) 97.37 - 2.07(100)
7.68 - 0.05(100)
4.45 - 0.03(100)
023605
Globulin Albumln/Globulin Total Bilirubin Direct Bilirubin SGOT SGPT GGTP A lkaline Phosphatase LDH
TABLE
7 - s.e.(n)
3.23 - 0.05(100) 1.41 - 0.03(100) 0.69 - 0.03(100) 0.19 - 0.01(100) 32.50 t 2.08(100) 43.41 t 3.10(100) 21.55 - 1.70(99) 31.13 - 0.80(100) 180.31 t 3.12(100)
C23606
ft
KBC RBC KGB HCT MCV MCH KCHC
TABLE
Y - s.e.(n)
7.02 - 0. 18(98) 5.14 - 0.44(98) 15.75 - 0 . 12( 98) 47.79 - 0. 36(98) 93.13 i 0.47(98) 30.71 - 0. 18(98) 32. 96 i 0 . 08(98)
C23607
Polys (X) lymphocytes (X) Monocytes (X) Eosinophils (X) Basophils (X)
TABLE ____
X i s.e.(n)
59.07 - 0.80(98) 30.70 - 0.74(98) 7.21 * 0.22(98) 2.30 - 0.13(98) 0.72 0.05(98)
C26608
Poly (Abs) lymph (Abs) Hono (Abs) Eos (Abs) Baso (Abs)
TABLE
J - s.e.(n)
4211.84 - 151.18(98)
2097.30 57.17(98) 497.62 17.40(98) 158.30 - 9.38(98) 49.38 - 3.20(98)
C3660
Blood Reference Range Units
Total Lipids (gm/dL) Cholesterol (mg/dL) Triglyceride (mg/dL) Total Cholesterol (mg/dL) C-KDL (ng/dl) C-LDL (mg/dl) C-VLDL (mg/dL)
TABLE
X s.e.(n)
0.67 - 0.02(99) 239.71 5.03(100) 182.95 - 9.19(100) 236.10 - 4.73(99) 46.71 t 1.81(99) 156.18 - 4.40(99) 33.91 * 2.81(99)
C3 6 610
PH Specific 6rev1ty
TABLE
l i i..(n) 5.29 0.05(98) 1.02300 0.00062(98}
C25611
Sodium (nmo 1/L) 134.00 - 146.00
TABLE ____ BLOOD REFERENCE RANGE UNITS
iS
100 100.00
Magnsium (meq/L)
< 1 .6 0 1.60 2.20 > 2 .2 0
2 2.00 85 85.00 13 13.00
Potassium (itmo 1/L)
3.50 - 5.50 > 5 .5 0
99 99.00 1 1.00
Chloride (nmo 1/L)
< 9 6 .0 0 96.00 - 110.00 >110.00
2 2.02 96 96.97
1 1.01
Calcium (mg/dL) < 8 .8 0 8.60 - 10.80
1 1.00 99 99.00
Phosphorus (mg/dL) < 2 .0 0 2.00 - 4.70
0 0.00 100 100.00
Iron (uq/dL)
< 4 5 .0 0 45.00 - 200.00 >200.00
1 1.00 97 97.00 2 2.00
BUN (mg/dL)
< 6 .0 0 6.00 - 25.00 >25.00
1 1.00 96 96.00
3 3.00
Creatinine (mg/dL) 0.50 - 1.70
100 100.00
BLOOD REFERENCE RANGE UNITS
TABLE
BUNfCreatinine Ratio 3.57 - 25.45
Uric A d d (mg/dL) 2.50 - 8.50 > 8 .5 0
Glucose (mq/dL) 65.00 - 130.00 >130.00
Total Protein {mg/dLj 6.60 - 8.90
100 100.00 92 92.00 8 8.00 97 97.00 3 3.00
100 100.00
BLOOD REFERENCE RANGE UNITS
Albutrfn (gm/dL)
<3.60
3.60 - 5.20 > 5 .2 0
TABLE
# 1 98 1
61obul1n (gm/dL) 1.90 - 3.70 >3.70
86 14
Albmrln/Globulln Ratio 0.46 - 2.63
100
Total BIHrubln (pg/dL) 0.10 - 1.70 > 1 .7 0
96 2
Direct B iliru b in (mg/dL)
0.00 - 0.30 > 0.30 :
93 7
Transaminase, SGO (IU/L) 1,00 - 50.00 >50.00
92 8
Transaminase, SGP (IU/L) 1.00 - 70.00 > 7 0 .0 0
92 8
G-glutamyl Transpeptldase CU/L)
1.00 - 70.00 >70.00
97 2
Alfcallnc Phosphatase (IU/L)
10.00 - 50.00 > 5 0 .0 0
96 2
LDH (IU/L)
90.00 - 250.00 >250.00
98 2
X
1.00 98.00
1.00
66.00 14.00
100.00
. 98.00 2.00
93.00 7.00
92.00 6.00
92.00 6.00
97.98 2.02
98.00 2.00
98.00 2.00
C23614
BLOOD REFERENCE RANGE UNITS
RBC (mllHons/cu.mm.) < 4 .6 4.6 - 6.2 > 6 .2
Hemoglobin (5 m/dL) < 1 4 .0 14.0 - 18.00 >18.00
Hematocrit (percent) <42.00 42.00 - 54.00 > 5 4 .0 0
MCV (eu.u)
<80.00
80.00 - 100.00 >100.00
MCH fuua) < 2 6 .0 0 26.00 - 33.00 > 33.00
MCHC (percent-) ^ 31.00 31.00 - 36.00
TABLE
%
5 5.10 92 93.88 1 1.02
3 3.06 92 93.88
3 2.04
3 3.06 93 94.90
2 2.04
1 1.02 92 93.88
5 5.10
2 2.04 88 89.80
8 8.16
2 2.04 96 97.96
C23615
BLOOD REFERENCE RANGE W ITS
CSC WBC (thousand/cu.wn.) 4.00 - 11.60 >11.60 D ifferent! al Polys (percent 42.0 42.0 - 81.0 > 8 1 .0
Lymphocytes (percent) 10.0 - 47.0 > 4 7 .0
Monocytes (percent)
0>.010-.010.0
Eosinophil1s (percent) 0.0 - 8.0
Basophils (percent) 0.0 - 2.0 > 2.0
TABLE
#_ 2 95 96.94
3 3.06
2 2.04
96 97.96 0 0.00
96 97.96 2 2.04 89 90.82 9 9.18 98 100.00 97 98.98 1 1.02
C236I6
BLOOD REFERENCE RANGE UNITS
TABLE
CSC D iffe re n tia l Absolute Values ( c e lls/eu.nm.)
#
Neutrophils 1650 -8330 >8330
96 2
Lymphocytes <1049 1049 - 3581 >3581
1 95 2
Monocytes 61 - 929 >929
97 1
Eosinophils <40 40 - 423
5 93
Basophils
10
10 - 148 >148
3 94
1
%
97.96 2.04
1.02 96.94 2.04
98.98 1.02
5.10 94.90
3.06 95.92
1.02
C2061
BLOOD REFERENCE RANGE W I T S
Total H olds (sffl/dL) 0.30 - 1.00 >1.00
Cholesterol (mg/dL) <125 125 - 300 >300
Triglyceride (mg/dL) 50 - 200 >200
Total Cholesterol (mg/dL) -125 125 - 300 >300
C-HDL fmq/dL) 30 3 0 -7 5 >75
C-LDL (mg/dL) ^ 60 60 - 185 >185
C-VLDL (mg/dL) 0.0 - 40.0 > 4 0 .0
TABLE
#
96 3
1 82 17
69 31
1 88 10
18 76
5
1 74 24
77 22
%
96.97 3.03
1.00 82.00 17.00
69.00 31.00
1.01 88.89 10.10
18.18 76.77 5.05
1.01 74.75 24.24
77.78 . 22.22
O<-rfOt'
Urinalysis
Appearance Clear
Sp ecific 6rav1ty 1.008 - 1.036
Acetone
1Negative
+
Albumin Negative
Glucose Negative 2+
Blood Negative
WBC Negative 0 -2 2 -5 5-10
RBC Negative 0 -2
Casts Negative
Bacteria None S lig h t Moderate
TABLE
X
98 100.00
98 100.00
97 1
981..0928
98 100.00
95 96.94 3 3.06
98 100.00
74
nn
7151..5212
11.22
2 2.04
97 98.98 1 1.02
98 100.00
87 88.78 10 10.20
1 1.02
C2G619
TABLE AGE AND EDUCATION
Age
Education High School High School Graduate Some College . College Graduate +
\
T -s .t.(n ) 44.17 1.10(100)
il 15 15.00 50 50.00 27 27.00 8 8.00
t
G2362
I
<
\
Table ___ Chloracne by Age and by Education
History Only
X + s.e.(n)
Residual Chloracne
X + s.e.(n)
Never Chloracne
X + s.e.(n)
p-value
Age 45.96 + 2.06(23)
#X
Education
<High School
0 0.00
High School Graduate 15 65.22
Some College
6 26.09
College Graduate +
2 8.70
44.64 + 1.47(42) #X
9 21.43 21 50.00 10 23.81
2 4.76
42.43 + 2.25(35) 0.4646
#% 6 17.14
. t,
14 40.00 11 31.43
*'
4 11.43
0.10<p<0.25
C23649
Length of Time in Building 236 (Months)
Length of Time Since Building 236 (Months)
Table
Chloracne by Length of Exposure and by Length of Time Since Cessation of Exposure
History Only
J _+ s.e. (n)
Residual X + s.e.(n)
Never J + s.e.(n)
p-value
38.14 + 7.74(22) 43.34 + 9.03(41) 2 5 .09+ 7.32(34) 0.2647
X,
135.01 + 26.52(22) 114.30 + 17.01(42) 142.49 + 22.34(34) 0.5779
C26650
'
Ever in #262 or #268
#262 before #236 #262 after #236
#268 before #236 #268 after #236
Table Chloracne versus Other Exposures at the Plant
Exposure Factors in Relation to Chloracne
Total
24 7
13 2 10
History Only (n=23)
#% 7 30.43
1 4.35
5 21.74
1 4.35
3 13.04
Residual _ (n=42T *% 9 21.43
3 7.14
4 9.52
0 0.00
5 11.90
Never T^33) #% 8 22.86
3 8.57
4 11.43
1 2.86
2 5.71
p-value
.7049 t i
.8259 .3538 .4415 .5711
C23651
Table Chloracne versus Other Plant Exposures
Ever in #237 Yes
Ever in #262 Yes
Ever in #268 Yes
History Only <n=23)
#%
Residual (n=42)
#%
13 56.52
22 52.38
Never (n=3S)
#%
p-value
21 60.00
(j.7973
6 26.09 3 13.04
7 16.67 5 11.90
6 17.14 0.75<p<0.90
2 5.71
0.5711
C2S652
Table Chloracne versus Previous Employment Exposures
Previous Employment Exposures
Mechanical Work Farming Dust Solvents Cutting Oils Welding/Soldering Fumes Fertilizer Weed Killer Asbestos Animal Feed Radiation Rubber Additives
History Only (n=23>
#% 7 30.43 0 0.00 6 26.09 8 34.78 3 13.04 7 30.43 1 4.35 2 8.70 1 4.35 0 0.00 0 0.00 0 0.00
Residual (n=42) '
#% 17 40.48
2 4.76 18 42.86 16 38.10 15 35.71 11 26.19
5 11.90 5 11.90 1 2.38 1 2.38 1 2.38 1 2.38
Never Tn=35)
p-value
#%
8 22.86 0.2519
0 0.00 0.2444
20 57.14 0.0649
15 42.86 0.8166
10 28.57 0.1498
10 28.57 0.9317
6 17.14 0.349
4 11.43 0.9202
1 . 2.86 0.9042
2 5.71 0.4376
- 1 2.86 0.7292
0 0.00 0.4979
C2G653
Table Chloracne versus Tobacco and Alcohol Use
Smoking Status
Never Former Present (Unknown)
Alcohol Status
Never Former Present
History Only # % Yes
Residual # % Yes
8 34.78 5 21.74 10 43.48 0
6 15.00 7 17.50 27 67.50
2
Never # % Yes
p-value
8 22.86
12 34.29 15 42.86
0
0.1141
3 13.04 1 4.35 19 82.61
1 2.38 5 11.90 36 85.71
3 8.57 5 14.29 27 77.14
;0.3958
-
X + s.e.(n)
X + s.e. (n)
X + s.e.(n)
Pack Years*
8.93 + 2.96(21) 27.06 + 4.42(35) 17.25 + 3.70(34) 0.0122
* p=0.0037 for comparison of history only to residual
Former Smokers 8.75 + 0.75(4) Pack Years
Present Smokers 16.94 + 5.85(9) Pack Years
23.29 + 6.96(7)
13.55 + 4.63(11) 0.2720
35.64 + 5.71(22) 29.17 + 6.30(15) 0.1674
Table Chloracne versus Family History of Illness
Family History
Asthma Hayfever Acne Eczema Hives
History Only # % Yes 9 39.13 5 21.74 7 30.43 3 13.04 2 8.70
Residual # % Yes 11 26.19 11 26.19 18 42.86 2 4.76 4 9.52
Never # % Yes 6 17.14 8 22.86 16 45.71 1 2.86 2 5.71
p-value
0.1747 0.9048 0.4861
i
0.2528 ff.8203
C23655
Table Chloracne versus Personal Medical History
Personal Medical History
History Only
% Yes
Headaches
12 52.17
High Blood Pressure 8 34.78
(confi rmed)
6
Bronchitis
8 34.78
Pneumonia (confirmed)
7 30.43 1
Pleurisy (confirmed)
3 13.04 2
Chest Pain (confirmed)
7 30.43 3
Kidney Trouble (confi rmed)
2 8.70 1
Bladder Trouble (confirmed)
3 13.04 2
Diabetes (confirmed)
0 0.00 0
Thyroid Problems (confirmed)
2 8.70 2
Stomach Ulcer (confirmed)
4 17.39 .4
Colitis (confirmed)
2 8.70 1
Liver Problems (confirmed)
2 8.70 2
Arthritis
8 34.78
Teenage Acne (MD treated)
5 21.74 0
Skin Boils (confirmed)
5 21.74 1
i
Residual Chloracne
J _ % Yes
22 52.38
5 11.90 5
9 21.43
5 11.90 5
7 16.67 5
12 28.57 12
4 9.52 2
6 14.29 3
2 4.76 1
2 4.76 0
7 16.67 7
4 9.52 4
2 4.76 2
12 28.57
19 45.24 2
18 42.86 5
Never Chloracne
Jf % Yes
p-value
21 60.00
0.7618
10 28.57 9
0.0694
6 17.14
0.2809
8 22.86 5
0.1769
TV
1 2.86 1
Q..1462
9 25.71 8
0.9207
0 0.00 0
0.1777
3 8.57 3
0.7330
2 5.71 2
0.5247
1 2.86 0
0.6051
7 20.00 6
0.9272
0 0.00 0
0.1777
1 2.86 1
0.6051
8 22.86
0.6093
14 40.00 2
0.1674
12 34.29 3
0.2316
C23656
Poison Ivy/Oak
Hives
Other Rash (confirmed)
Skin Cancer (confirmed)
Prostate Cancer (confirmed)
History Only
* Yes
9 39.13
3 13.04
12 52.17 8
1 4.35 1
0 0.00 0
Table
Residual Chloracne
_# % Yes
17 40.48
4 9.52 18 42.86 17 0 0.00 0 0 0.00 0
Never Chloracne
% Yes
8 22.86
7 20.00
14 40.00 10
1 2.86 0
1 2.86 1
p-value
0.2241 0.4142 0.6462
0.4415 0.3914
C23657
Vital Signs
Quetelet Index (Height/Weight xlOO)
Systolic BP Diastolic BP Pulse Respiration Height Weight Temperature
Table
Chloracne versus Vital Signs
History Only
X :* s.e.(n)
Residual Chloracne
I + s.e.(n)
Never Chloracne
J + s.e.(n)
p-value
38.72 + 1.24(23)
36.62 + 0.90(42)
38.27 + 1.16(35)
0.3436'
i. ..r
123.57 + 2.85(23) 75.09 + 1.60(23) 74.35 + 2.31(23) 19.91 + 1.43(23) 70.78 + 0.56(23)
187.43 + 6.79(23) 97.76 + 0.14(22)
119.79 + 2.48(42) 71.71 + 1.53(42) 77.38 + 1.58(42) 19.54 + 0.49(39) 69.24 + 0.41(42) 194.29 + 5.56(42) 97.87 + 0.10(40)
123.71 + 3.07(35) 75.71 + 2.14(35) 74.03 + 2.21(35) 18.63 + 0.54(35) 69.86 + 0.46(35)
189.17 + 6.72(35) 97.85 + 0.11(33)
0C5071
0 :2 1 3 7
0.3836 0.4900 0.0909 0.7262 0.8156
C23658
Table Chloracne versus Dermatologic Findings
Dermatologic Findings
History Only (n=23)
_ % Yes
Chloracne Actinic Elastosis
23 100.00 4 17.39
Severity MTT3-----Moderate
Severe
.
3 0
1
Where . Face
Neck
2 3
Malar Hirsutism
1 4.35
History Acne Vulgaris
6 26.09
Acne Vulgaris
1 4.35
Severity Mild Moderate
1 0
Folliculitis
4 17.39
Actinic Keratoses
2 8.70
Basal Cell Epithelioma 0
0.00
Squamous Cell Epithelioma
0 0.00
Seborrheic Dermatitis 1
4.35
Dermatophytes is
Hands Feet
Nails Other
0 8 1 2
Psoriasis
0 0.00
Atopic Dermatitis
0 0.00
Residual Chloracne
(n42) _# % Yes 42 100.00
4 9.52
1 3 0
4 2 4 9.52
18 42.86 4 9.52
2 2 5 11.90 1 2.38 0 0.00
0 0.00 5 11.90
0 12
3 7 0 0.00 0 0.00
Never Chloracne
(n:=35) _ % Yes
0 0.00 4 11.43
2 1 1
4 0 0 0.00
18 51.43 15 42.86
15 0 1 2.86 0 0.00 0 0.00
0 0.00 3 8.57
p-value
__ -- --
0.6415
t
0.1588
0.1695 0.1571
-- --
0.5920
1 10
2 3
0 0.00
--
1 2.86
0.3914
C26650
Poikiloderma
Face Neck Chest Other
Dermatofibroma
Lipoma
Pigmented Nevi
Rosacea/Rhi nopbyma
Lichen Simplex ' Chronicus
Alopecia, Other
Neurofibroma
Leukoderma
Petechiae Ecchymoses
Dupuytren1s Contracture
Junctional Nvi
Lymphadenopathy
Livedo Reticularis
Xerosis
Pilonidal Cyst
Otitis Externa
Mild Chronic Dermatitis
Xanthelasma
Seborrheic Keratoses
History Only
# % Yes
1 0 0 1 0 0.00 0 0.00 0 0.00 2 8.70
0 0.00 0 0.00 0 0.00 0 0.00 0 0.00
1 4.35 0 0.00 1 4.35 0 0.00 1 4.35 0 0.00 1 4.35
1 4.35 0 0.00 1 4.35
Table
Residual Chloracne _# X Yes
0 0 0 0 0 0.00 2 4.76 2 4.76 1 2.38
2 4.76 0 0.00 0 0.00 0 0.00 0 0.00
0 0.00 1 2.38 1 2.38 1 2.38 1 2.38 0 0.00 1 2.38
0 0.00 1 2.38 3 7.14
Never Chloracne
% Yes
p-value
0 0 0 0 1 2.86 2 5.71 5 14.29 2 5.71
1 2.86 0 0.00 0 0.00 0 - 0.00 1 2.86
0 0.00 0 0.00 0 0.00 1 2.86 2 5.71 0 0.00 0 0.00
0 0.00 0 0.00 4 11.43
0.3914 0.5247 0.0859 0.5206*
%
'6.5594
--
0.3914
0.1844 0.4979 0.4985 0.7292 0.7551
--
0.4985
0.1844 0.4979 0.6012
C2S6'
Table Chloracne versus Clinical Laboratory Findings
Sodium (age adjusted)
Magnesium (age adjusted)
Potassium (age adjusted)
Chloride (age adjusted)
Calcium (age,adjusted)
Phosphorous (age adjusted)
Iron (age adjusted)
BUN (age adjusted)
Creatinine (age adjusted)
BUN/Creatinine (age adjusted)
Uric Acid (age adjusted)
Glucose (age adjusted)
History Only
X + s.e.(n)
139.70 + 0.48(23) 139.67 + 0.53
2.05 + 0.04(23) 2.04 + 0.04
4.60 + 0.07(23) 4.59 + 0.09
104.45 + 0.42(22) 104.48 + 0.74
9.73 + 0.07(23) 9.73 + 0.08
2.91 + 0.08(23) 2.92 + 0.08
118.70 + 10.50(23) 120.35 + 7.07
14.65 + 0.61(23) 14.59 + 0.84
1.32 + 0.02(23) 1.32 + 0.04
11.16 + 0.52(23) 11.11 + 0.77
6.18 + 0.27(23) 6.16 + 0.30
91.96 + 1.35(23) 91.04 + 4.18
Residual Chloracne
X + s.e.(n)
Never Chloracne
X + s.e.(n)
p-value
138.81 + 0.43(42) 139.03 + 0.40(35)
138.80 + 0.39
139.06 + 0.43
0.3999 0.4254
2.00 + 0.03(42) 2.00 + 0.03
2.00 + 0.04(35) 2.01 + 0.04
0.6680 0.7307
4.43 + 0.07(42) 4.43 + 0.06
4.52 + 0.07(35) 4.53 + 0.07
0.2790 0.2838
103.67 + 0.55(42) 102.89 + 0.67(35) ^0.2418
103.67 + 0.53
102.86 + 0.59
=: 0.2299
9.74 + 0.06(42) 9.74 + 0.06
9.81 + 0.06(35) :"0.6501
9.81 + 0.07
: 0.6908
2.82 + 0.05(42) 2.82 + 0,06
2.81 + 0.06(35) 2.80 + 0.06
0.5220 0.4597
103.38 + 4.58(42)= 112.97 + 4.85(35)
103.82 + 5.22
111.36 + 5.74
0.2131 0.1701
15.10 + 0.62(42) 15,08 + 0.62
15.09 + 0.77(35) 15.15 + 0.68
0.8993 0.8614
1.27 + 0.03(42) 1.27i + 0.03 '
1.34 + 0.04(35) 1.34 + 0.04
12.36 + 0.65(42) ' 11.63 + 0.63(35)
12.35 + 0.57
11.67 + 0.63
0.3007 0.2903
O'.4244 0.4213
6.26 + 0.21(42) 6.26 + 0.22
6.16 + 0.27(35) 6.18 + 0.25
0.9484 0.9576
99.10 + 4.37(42)' 98.85 + 3.08
98.86 + 2.52(35) 99.75 + 3.39
0.3615 0.2274
C236Ci
Table
History Only
Total Protein Cage adjusted)
x s. e. (n) 7.67 + 0.10(23) 7.68 T 0.11
Albumin (age adjusted)
4.50 + 0.05(23) 4.51 7 0.07
Globulin (age adjusted)
3.17 + 0.08(23) 3.16 T 0.10
Albumin/Globulin (age adjusted)
1.44 + 0.04(23) 1.44 7 0.05
Total Bilirubin (age adjusted)
0.69 + 0.03(23) 0.70 T 0.06
Direct Bilirubin (age adjusted)
0.19 + 0.01(23) 0.19 7 0.02
SGOT (age adjusted)
35.78 + 7.53(23) 35.26 7 4.35
SGPT (age adjusted)
50.61 + 11.48(23) 50.01 7 6.48
GGTP (age adjusted)
21.09 + 3.01(23) 20.67 7 3.52
Alkaline Phosphatase 31.00 + 1.41(23)
(age adjusted)
30.88 7 1.67
LDH (age adjusted)
176.78 + 5.98(23) 176.97 7 6.62
Residual Chloracne
Never Chloracne
p-value
X + s.e.(n)
J + s.e.(n)
7.67 + 0.08(42) 7.68 + 0.08
7.69 + 0.09(35) 7.68 + 0.09
0.9838 0.9980
4.39 + 0.07(42) 4.50 + 0.04(35)
4.39 7 0.05
4.48 + 0.06
0.3106 0.3243
3.28 + 0.09(42) 3.28 + 0.08
3.19 + 0.08(35) 3.20 + 0.08
0.6057 0.6111
1.38 + 0.05(42) 1.38 + 0.04
1.44 + 0.04(35) 1.43 + 0.04
0.5599 0.5808
0.72 + 0.06(42) 0.72 7 0.05
0.67 + 0.04(35) 0.67 + 0.05
0.8004 0.7718
0.20 + 0.02(42) 0.20 + 0.02
0.18 + 0.01(35)-: 0.8071
0.18+0.02
5 0.7732
32.14 + 2.03(42) 32.00 +3.21
30.77 + 2.40(35) 31.28 + 3.54
0.6668 0.7638
39.88 + 2.14(42) 39.72 + 4.78
42.91 + 3.99(35) 43.50 + 5.26
0.4122 0.4444
19.20 + 2.22(41) 19.07 + 2.63
24.60 + 3.54(35) 25.03 + 2.86
0.3818 0.3018
30.29 + 1.44(42) 30.25 + 1.23
32.23 + 1.16(35) 32.34 + 1.36
0.5682 0.5194
181.76 + 4.73(42) 181.81 + 4.88
180.89 + 5.76(35) 180.71 + 5.37
0.8234 0.8374
C266S2
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T0 (c*e<Diu--
Polys (%) (age adjusted)
Lymphocytes 0 0 (age adjusted)
Monocytes (%) (age adjusted)
Eosinophils (3) (age adjusted)
Basophils OS) (age adjusted)
Table
History Only
jf + s.e. (n)
Residual Chloracne
J + s.e.(n)
Never Chloracne
X + s.e.(n)
p-value
60.36 + 1.56(23) 60.14 + 1.63
29.02 + 1.61(23) 29.24 + 1.51
7.35 + 0.43(23) 7.34 + 0.45
2.62 + 0.31(23) 2.63 + 0.27
0.65 + 0.09(23) 0.65 + 0.10
59.70 + 1.19(40) 59.67 + 1.23
30.12 + 1.11(40) 30.15 + 1.14
7.22 + 0.38(40) 7.22 + 0.34
2.21 + 0.19(40) 2.21 + 0.20
0.76 + 0.09(40) 0.76 + 0.07
57.51 + 1.43(35) 57.69 + 1.32
0.3288 0.4249
32.46 + 1.24(35) 32.28 + 1.23
0.1792 0.2526
7.12 + 0.32(35) 7.12 + 0.37
:0.9233 i0.9349
2.19 + 0.21(35) '-0.3901
2.18 + 0.22
-'0.3728
0.73 + 0.06(35) 0.73 + 0.08
0.6772 0.6900
C236o4
Table
History Only
X + s. e.(n)
Residual Chloracne
X + s.,e.(n)
Never Chloracne
X + s.e. <(n)
p-value
Poly (Abs)
4077.70 + 313.90(23)
(age adjusted) 4010.17 + 305.65
Lymph (Abs)
1886.83 + 125.30(23)
(age adjusted) 1875.95 + 116.95
Mono (Abs) (age adjusted)
488.70 + 38.99(23) 483.55 + 35.94
Eos (Abs) (age adjusted)
171.96 + 20.51(23) 171.39 + 19.65
Baso (Abs) (age adjusted)
42.04 + 6.36(23) 41.69 + 6.65
4405.15 + 229.14(40) 4395.40 + 230.95
2148.48 + 95.06(40) 2146.90 + 88.37
516.15 + 29.29(40) 515.41 + 27.16
156.83 + 13.96(40) 156.74 +_ 14.84
54.05 + 5.85(40) 54.00 + 5.03
4079.06 + 264.05(35) 0.5738
4134.57 + 247.80
0.5596
2177.11 + 80.36(35)t .0.1219.. 2186.05 + 94.82 } 0.0985
482.31 + 25.07(35); 0.6746
486.55 + 29.14
0.6956
151.00 + 16.21(35) 0.7004
151.46 + 15.93
0.7286
48.86 + 4.25(35) 0.3520
49.15 + 5.39
0.3395
C286o5
Table
ood ference Range Units
History Only
X +_ s. e.(n)
Residual Chloracne
X + s,.e.(n)
Never Chloracne
X + s.e. (n)
p-value
tal Lipids (gm/dL) ge adjusted)
olesterol (mg/dL) ge adjusted)
iglyceride (mg/dL) ige adjusted)
)tal Cholesterol (mg/dL) ige adjusted)
-HDL (mg/dL) ige adjusted)
0.66 + 0.03(23) 0.65 +_ 0.04
238.39 + 8.20(23)
236.57 + 10.41 163.96 + 14.39(23) 162.10 + 19.12 232.26 + 8.00(23) 230.49 + 9.73 48.65 + 3.24(23) 49.00 + 3.68
0.67 + 0.03(41) 0.67 + 0.03
0.68 + 0.04(35) 0.68 + 0.03
239.74 + 9.51(42) 240.54 + 7.13(35)
239.26 + 7.69
242.32 + 8.45
199.55 + 16.05(42) 175.51 + 14.96(35)
199.06 + 14.11
177.32 + 15.52
233.66 + 8.28(41) 241.49 + 7.70<3):
233.38 + 7.26
242.97 + 7.89 v;
41.32 + 2.66(41) 51.74 + 3.29(35)
41.37 + 2.75
51.45 + 2.99 -
0.8901 0.7835
0.9876 0.9105
0.2778 O'.2728
0.7012 0.5450
0.0344* 0.0394*
p=0.Q117 for comparison of residual chloracne to never chloracne p=0.Q148 for comparison of residual chloracne to never chloracne
1
-LDL (mg/dL) age adjusted)
-VLDL (mg/dL) age adjusted)
152.13 + 7.21(23) 150.53 + 9.08 32.17 + 4.40(23) 31.37 + 5.85
158.98 + 7.98(41)
158.72 + 6.78
34.61 + 2.43(41)
34.48 + 4.37
155.57 + 6.88(35)
156.92 + 7.37
34.23 + 6.91(35) 34.91 + 4.74
0.8337 0.7649
0.9432 0.8831
C26636
Table
History Only
1 + s.e.(n)
Residual Chloracne
7 + s.e .(n)
i ge adjusted)
jecific Gravity ige adjusted)
5.17 5.19
+ +
1.02352 + 1.0237 +
0.08 (23) 0.11
0.0808 (23) 0.0013
5.27 5.27
+ 0.08 (41) + 0.08
1.0220 + 0.0010 (41) 1.0220 + 0.0010
Never Chloracne
7 + s.e. (n)
5.38 5.37
+ +
1.0239 + 1.0237 +
0.10 (34 0.09
0.0009 (34 0.00106
C2S637
Table ___ Chloracne v Clinical Laboratory Findings
Blood Reference Range Units
Sodium(tmol/L) 134.00 - 146.00
Magnesium(meq/L)
< 1.60 1.60 - 2.20 > 2.20
Potassium(imol/L) 3.50 - 5.50 . > 5.50
Chloride (ititioT/L ) < 96.00 * 96.00 - 110.00 > 110.00
Calcium(mg/dL)
< 8.80 8.80 - 10.80
Phosphorus(mg/dL)
* 2.00 - 4.70
Iron(ug/dL)
< 45.00 45.00 - 200.00 > 200.00
BUN(mq/dL)
< 6.00 6.00 - 25.00 > 25.00
Creatinine(mg/dL)
0.50 - 1.70
Bun/Creatinine Ratio 3.57 - 25.45
Uric Acid(mg/dL)
2.50 - 8.50 > 8.50
History 1Only
#%
23 100.00
1 4.35 18 78.26
4 17.39
23 100.00 0 0.00
0 - 0.00 22 100.00
0 0.00
0 0.00 23 100.00
23 100.00
1 4.35 20 86.96
2 8.70
0 0.00 23 100.00
0 0.00
23 100.00
23 100.00
22 95.65 1 4.35
Residual Chloracne
#%
Never Chloracne
#%
p-value
12 100.00
35 100.00
1 2.38 36 85.71
5 11.90
0 0.00 31 88.57 4 11.43
0.7378
42 100.00 0 0.00
34 97.14 1 2.86
0.3914
0 0.00 42 100.00
0 0.00
2 5.71
32 91.43 1 2.86
L.*' * 0.2263
1 2.38 41 97.62
0 0.00 35 100.00
>0.4979
42 100.00
35 100.00
0 0.00 42 100.00
0 0.00
0 0.00 35 100.00 0 0.00
0.0349*
1 2.38 40 95.24
1 2.38
0 0.00
33 94.29 2 5.71 *
0.5519
42 100.00
35 100.00
--
42 100.00
38 90.48 4 9.52
35 100.00
32 91.43 3 8.57
C2S668
0.7540
Uarninn* fivpr 2 of the cell have expected counts of less than 5. Table is so
Table Chloracne v Clinical Laboratory Findings
Blood Reference Range Units
History Only
#%
G1ucose(mg/dL)
65.00 - 130.00 > 130.00
23 100.00 0 0.00
Total Protein(gm/dL) 6.60 - 8.90
23 100.00
Albumin(gm/dL)
< 3.60 3.60 - 5.Z0 > 5.20
0 0.00 23 100.00
0 0.00
Globulin(gm/dL)
1.90 - 3.70 > 3.70
21 91.30 2 8.70
Albumin/Globulin Ratio 0.46 - 2.63
23 100.00
Total Bilirubin(mg/dL)
0.10 - 1.70 > 1.70
23 100.00 0 0.00
Direct Bilirubin(mg/dL)
0.00 - 0.30 > 0.30
23 100.00 0 0.00
Transaminase, SG0(IU/L)
1.00 - 50.00 > 50.00
22 95.65 1 4.35
Transaminase, SGP(IU/L)
1.00 - 70.00 > 70.00
21 91.30 2 8.70
G-glutamyl Transpeptidase (U/L)
1.00 -'70.00 > 70.00
23 100.00 0 , 0.00
Alkaline Phosphatase(IU/L)
10.00 - 50.00 > 50.00
23 100.00 0 0.00
LDH(IU/L)
90.00.- 250.00
23 100.00
Residual Chloracne
#%
41 97.62 1 2.38
42 100.00
1 2.38 40 95.24
1 2.38
35 83.33 7 16.67
42 100.00
40 95.24 2 4.76
40 95.24 2 4.76
39 92.86 3 7.14
40 95.24 2 4.76
41 100.00 0 0.00
40 95.24 2 4.76
41 97.62
Never Chloracne
#%
p-value
33 94.29 2 5.71
0.4376
35 100.00
0 0-.00 35 100.00
0 0.00
0.5887
30 85.71 5 14.29
0.6744>
35 100.00
35 100.00 0 0.00
0.2444
30 85.71 5 14.29
0.0859
31 88.57 4 11.43
0.6012
31 88.57 4 11.43
0.5564
33 94.29 2 5.71
0.1547
35 100.00 0 0.00
0.2444
C2669
344 97a.1n4r
n Jono
Table Chloracne v Clinical Laboratory Findings
Blood Reference Range Units
RBC(mi11 ions/cu.mm.)
< 4.6 4.6 - 6.2 > 6.2
Hemoglobin(gm/dL)
< 14.0 14.0 - 18.00 > 18.00
Hematocrit(percent)
< 42.00 42.00 - 54.00 > 54.00
MCV(cu.u)
< 80.00 80.00 - 100.00 > 100.00
MCH(uug)
< 26.00 26.00 - 33.00 > 33.00
MCHC(percent)
< 31.00 31.00 - 36.00
History Only
#%
Residual Chloracne
#%
Never Chloracne
l%
p-value
0 0.00 23 100.00
0 0.00
1 2.50
"39 97.50 0 0.00
4 11.43 30 85,71
1 2.86
0.1558
0 0.00 23 100.00
0 0.00
0 0.00 23 100.00
0 0.00
2 5.00 37 92.50
1 2.50
1 2.'50 38 95.00
1 2.50
1 2.86 32 91.43
2 5.71
2 5.71 32 91.43
1 2.86
j" 0.5794
;'
0.6840
0 0.00 22 95.65
1 4.35
1 2.50 36 90.00
3 7.50
0 0.00 34 97.14
1 2.86
0.6656
0 0.00 23 100.00
0 0.00
1 2.50 35 87.50
4 10.00
1 2.86 30 85.71
4 11.43
0.4809
0 0.00 23 100.00
1 2.50 39 97.50
1 2.86 34 97.14
0.7269
C2S670
Table Chloracne v Clinical Laboratory Findings
Blood Reference Range Units
CBC
WBC(thousand/cu.mm.)
4.00 - 11.60 > 11.60
Differential Pofys(percent)
< 42.00 42.00 - 81.0 > 81.0
Lymphocytes(percent)
10.0 - 47.0 > 47.0
Monocytes(percent
0.0 - 10.0 > 10.0
EosinophiIs(percent)
0.0 - 8.0
Basophils(percent)
0.0 - 2.0 > 2.0
History Only
#%
Residual Chloracne
#%
Never Chloracne
#%
p-value
22 95.65 1 4.35
0 0.00 23 100.00
0 0.00
39 97.50 1 2.50
34 97.14 1 2.86
0 0.00
2 5.71
40 100.00
33 94.29
0 0.00 , 0 0.00
0.9159
i
; 0.1529
23 100.00 0 0.00
40 100.00 0 0,00
33 94.29 2 5.71
0.1592
20 86.96 3 13.04
35 87.50 5 12.50
34 97.14 1 2.86
0.2701
23 100.00
40 100.00
35 100.00
23 100.00 0 0.00
39 97.50 1 2.50
35 100.00 0 0.00
0.4807
C2S671
Table Chloracne v Clinical Laboratory Findings
Blood Reference Range Units
CBC
Differential Absol uteValues(cel1s/cu.rmi)
Neutrophils
1650 - 8330 > 8330
Lymphocytes
< 1049 1049 - 3581 > 3581
Monocytes
61 - 929 > 929
Eosinophils
< 40 40-423
Basophils
< 10 10 - 148 > 148
History Only
#%
23 100.00 0 0.00
1 , 4.35 22 95.65
0 0.00
23 100.00 0 0.00
1 4.3S 22 95.65
2 8.70 21 91.30
0 0.00
Residual Chloracne %
39 97.50 1 2.50
Never Chloracne
%
p-value i .,,
34 97.14 1 2.86 . . 0.7269
0 0.00 39 97.50
1 2.50
0 0.00 34 97.14
1 2.86
0.4209
39 97.50 . 35 100.00
1 2.50
0 0.00
0.4807
1 2.50 39 97.50
3 8.57 32 91.43
0.4828
0 0.00 39 97.50
1 2.50
1 2.86 34 97.14
0 0.00
0.2741
Table Chloracne versus C lin ic a l Laboratory Findings
Blood Reference Range Units
Total Lipids(gm/dL)
0.30 - 1.00 > 1.00
Cholesterol(mg/dL)
< 125 125-300 > 300
Triglyceride(mg/dL)
50 - 200 > 200
Total Cholesterol(mg/dL)
< 125 125 - 300 > 300
C-HOUmg/dL)
< 30 3 0 -7 5 > 75
C-LDL(mg/dl)
< 60 60 - 185 > 185
C-VLDL(mg/dL)
0.0 - 40.0 > 40.0
History Only
#%
Residual Chloracne
X
Never Chloracne
X
p-value
22 95.65 1 4.35
40 97.56 1 2.44
34 97.14 1 2.86
0.9102
0 0.00 21 91.30 2 8.70
1 2.38 33 78.57 8 19.05
0 0.00 28 80.00
7 20.00
19 82.61 4 17.39
25 59.52 17 40.48
25 71.43 10 28.57
0.5708
V
0.1438
0 0.00 21 91.30 2 8.70
1 2.44 34 82.93
6 14.63
0 0.00 33 94.29 2 5.71
0.5162
3 13.04 20 86.96 0 0.00
9 21.95 31 75.61
1 2.44
6 17.14 25 71.43 4 11.43
0.2262
0 0.00 18 78.26
5 21.74
1 2.44 29 70.73 11 26.83
0 0.00 27 77.14 8 22.86
0.7783
19 82.61 4 17.39
26 63.41 15 36.59
32 91.43 3 8.57
0.0112
*p*0.0112 for comparison o f reslduil chloracne to never chloracne.
C25673
Table
Chloracne versus Clinical Laboratory Findings
Urinalysis
Appearance
Clear
Specific Gravity
1.008 - 1.036
Acetone
Negative 1+
Albumin
Negative
Glucose
Negative 2+
Blood
5
Negative
WBC
Negative 0-2 2-5
5-10
RBC
Negative 0-2
Casts
Negative
Bacteria
None Slight Moderate
History Only
X
Residual Chloracne
%
Never Chloracne
X
P-value
23 100.00 41 100.00 34 100.00
23 100.00 41 100.00 34 100.00
22 95.65 1 4.35
41 100.00 0 0.00
34 100.00 0 0.00
0.1926
23 100.00 41 100.00 34 100.00 --
23 100.00 0 0.00
40 97.56 1 2.44
32 94.12 2 5.88
1m 0.4292
23 100.00 41 100.00 34 100.00
15 65.22
6 26.09 2 8.70 0 0.00
32 78.05
3 7.32 5 12.20 1 2.44
27 79.41
2 5.88 4 11.76 1 2.94
.25<p<.50
22 95.65 1 4.35
41 100.00 0 0.00
34 100.00 0 0.00
0.1926
23 100.00 41 100.00 34 100.00
21 91.30 2 8.70 0 0.00
38 92.68 2 4.88 1 2.44
28 82.35
6 17.65 0 0.00
0.3226
C23674
I Table Chloracne versus Clinical Laboratory Findings
Urinalysis
Crystals None Uric Acid Calcium Oxalate
Yeast Negative
PH 5 6 7
History Only
#X
Residual Chloracne
#X
Never Chloracne
#X
p-yalue
23 100.00 0 0.00 0 0.00
39 95.12 0 0.00 2 4.88
'34 100.00 0 0.00 0 0.00
23 100.00 41 100.00 34 100.00
0.2419
.
19 82.61 4 17.39 0 0.00
31 75.61 9 21.95 1 2.44
23 67.65 9 26.47 2 5.88
0.6312
G2567
t
Table ___ Severity of Chloracne versus Demographic Factors
Age
Education < High School High School Graduate Some College College Graduate+
Wild
X + s.e. (n)
44.69 + 1.75(29)
% 7 24.14 13 44.83 7 24.14 2 6.90
Moderate
X + s.e.(n)
44.54 +2.80(13)
p-value
0.9627 c
% 2 15.38 8 61.54 3 23.08 0 0.00
\ 0.50 < p <0.75
323676
Table
Severity of Chloracne versus Length of Exposure and Length of Time since Cessation of Exposure
Length of Time in Building 236 (Months)
Length of Time Since Building 236 (Months)
Mild
X +_ s.e. (n)
47.68 + 12.37(28)
Moderate
X + s.e. (n)
34.00 + 10.23(13)
p-value 0.4878
118.44 + 19.84(29)
105.05 + 33.70(13)
0.7208
C2667V
Table Severity of Chloracne versus Other Plant Exposures
Ever in #237 Yes
Ever in #262 Yes
Ever in #268 Yes
Mild (n=29) #% 15 51.72
4 13.79
3 10.34
Moderate (n=13)
#% 7 53.85
3 23.08
2 15.38
p-value
X
1.0000 0.6567 0.6370
C23678
Table Severity of Chlorance versus Previous Employment Exposures
Previous Employment
Mechanical Work Farming Oust Solvents Cutting Oils Welding/Soldering Fumes Fertilizer Weed Killer Asbestos Animal Feed Radi ation Rubber Additives
Mild (n=29) #X 10 34.48 2 5.90 15 51.72 11 37.93 9 31.03 8 27.59 4 13.79 2 5.90 1 3.45 1 3.45 1 3.45 1 3.45
Moderate (n=13)
#% 7 53.85 0 0.00 3 23.08 5 38.46 6 46.15 3 23.08 1 7.69 3 23.08 0 0.00 0 0.00 0 0.00 0 0.00
p-value
0.3141 1.0000 0.103f8 1.0000 0.488 1.0000 1.0000 0.1624 1.0000 1.0000 1.0000 1.0000
C2367V
Table Severity of Chloracne versus Alcohol and Tobacco Use
Smoking Status
Never Former Present (Unknown)
Mi 1d (n=29)
# % Yes
5 17.86 5 17.86 18 64.29 1
Moderate (n=13) "
# % Yes
1 8.33 2 16.67 9 75.00 1
p-value 0.7198
Alcohol Status
Never Former Present
0 0.00
3 10.34 26 89.66
1 7.69 2 15.38 10 76.92
0.2736
Pack Years
J + s.e.(n) 23.10 + 4.72(25)
X + s.e. (n) 36.95 + 9.70(10)
0.1598
C2-363U
Table Severity of Chloracne versus Family History of Illness
Family History
* Asthma Hayfever Acne Eczema Hives
Mild (n~29) % Yes . 9 31.03 6 20.69 12 41.38 1 3.45 4 13.79
Moderate (n=13 >
% Yes 2 15.38 5 38.46 6 46.15 1 7.69 0 0.00
p-value
0.4525 0.2700 1.0000 0.52S5 0.2927
C2S63
Table Severity of Chloracne versus Personal Medical History
Personal Medical History
Mild <n=29)
% Yes
Headaches
15 51.72
High Blood Pressure
4 13.79
Bronchitis
7 24.14
Pneumonia*
4 13.79
Pleurisy
5 17.24
Chest Pain
9 31.03
Kidney Trouble
4 13.79
Bladder Trouble
5 17.24
Diabetes
1 3.45
Thyroid Problems
2 6.90
Stomach Ulcer
5 17.24
Colitis
4 13.79
Liver Problems
2 6.90
Arthritis
8 27.59
Teenage Acne
13 44.83
Skin Boils
12 41.38
Poison Ivy/Oak
14 48.28
Hives
3 10.34
Other Rash
14 48.28
Skin Cancer
0 0.00
Prostate Cancer
0 0.00
Moderate (n=T3J
# % Yes 7 53.85 1 7.69 2 15.38 1 7.69 2 15.38 3 23.08 0 0.00 1 7.69 1 7.69 0 0.00 2 15.38 0 0.00 0 0.00 4 30.77 6 46.15 6 46.15 3 23.08 1 7.69 4 30.77 0 0.00 0 0.00
p-value
1.0000 1.0000 0.6953 1.0000 1.0000 0.722& 0.2927 0.6468 0.5285 1.0000 1.0000 0.2927 1.0000 1.0000 1.0000 1.0000 0.1791 1.0000 0.3334
C2S632
Table Severity of Chloracne versus Vital Signs
Vital Signs
Quetelet Index (Height/Weight x 100) Systolic BP Diastolic BP Pulse Respiration Height Weight Temperature
Mild X + s.e .(n) 37.29 + 0.98(29)
Moderate X + s.e .(n) 35.13 + 1.90(13)
p-value 0.2706
117.93 + 3.02(29) 70.21 + 1.96(29) 78.69 + 2.03(29) 19.41 + 0.64(27) 68.62 + 0.48(29)
187.45 + 4.99(29) 97.86 + 0.12(28)
123.92 + 4.24(13) 75.08 + 2.13(13) 74.46 + 2.22(13) 19.83 + 0.72(12) 70.62 + 0.67(13)
209.54 + 13.55(13) 97.88 + 0.15(12)
0.2683 ti *
0.1435 0.2194 0.6938 0.0236 0.0654 0.9018
C2363J
Table Severity of Chloracne versus Dermatologic Findings
Dermatologic Findings
Mild (n=29)
# % Yes
Actinic Elastosis
2 6.90
Severity Mild
Moderate Severe
1 1 0
Where
Face Neck
2 0
Malar Hirsutism
3 10.34
History Acne Vulgaris
10 34.48
Acne Vulgaris
1 3.45
Severity Mild Moderate
1 0
Folliculitis
2 6.90
Actinic Keratoses
0 0.00
Basal Cell Epithelioma
0 0.00
Squamous Cell Epithelioma 0
0.00
Seborrheic Dermatitis
5 17.24
Dermatophytosis
Hands Feet
Nai Is Other
0 0.00 8 27.59 3 10.34 5 17.24
Psoriasis
0 0.00
Atopic Dermatitis
0 0.00
Moderate (n=13)
# % Yes 2 15.38
0 2 0
2 2 1 7.69 8 61.54 3 23.08
1 2; 3 23.08 1 7.69 0 0.00 0 0.00 0 0.00
0 0.00 4 30.77 0 0.00 2 15.38 0 0.00 0 0.00
p-value
0.5756
i 1.0000 0.1766 0.0805
0.1624 0.3095
0.3020
1.0000 0.5402 1.0000
Table Severity of Chloracne versus Dermatologic Findings
Dermatologic Findings
Poikiloderma Face Neck Chest Other
Dermatofibroma Lipoma Pigmented Nevi Rosacea/Rhinophyma Lichen Simplex Chronicus Alopecia Other Neurofibroma Leukoderma Petechiae Ecchymoses Dupuytren's Contracture Junctional Nevi Lymphadenopathy Livedo Reticularis Xerosis Pilonidal Cyst Otitis Externa Mild Chronic Dermatitis Xanthelasma Seborrheic Keratoses
Mild (n=29) # % Yes
0 0.00 0 0,00 0 0.00 0 0.00 0 0.00 0 0.00 2 6.90 1 3.45 1 3.45 0 0.00 0 0.00 0 0.00 0 0.00 0 0.00 1 3.45 0 0.00 1 3.45 i 3.45 0 0.00 0 0.00 0 0.00 0 0.00 2 6.90
Moderate (n:=13)
# % Yes
p-vaiue
0 0 0 0 0 2 0 0 1 0 0 .0 0 0 0 1 0 0 0 1 0 1 1
0.00 0.00 0.00 0.00 0.00 15.38 0.00 0.00 7.69 0.00 0.00 0.00 0.00 0.00 0.00 7.69 0.00 0.00 0.00 7.69 0.00 7.69 7.69
0.0906 1.00O 1.0000 0.5285
1.0000 0.3095 1.0000 1.0000
0.3095
0.3095 1.0000
C2363
Severity of Chloracne versus Clinical Laboratory Findings
Sodium (age adjusted)
Magnesium (age adjusted)
Potassi urn (age adjusted)
Chloride (age adjusted)
Calci um (age adjusted)
Phosphorous (age adjusted)
Iron (age adjusted)
BUN (age adjusted)
Creatinine (age adjusted)
BUN/Creatinine (age adjusted)
Uric Acid (age adjusted)
Glucose (age adjusted)
Mild
X + s.e.(n)
138.48 + 0.50(29) 138.48 + 0.52
2.01 + 0.04(29) 2.01 + 0.04
4.42 + 0.09(29) 4.42 + 0.08
103.31 + 0.67(29) 103.31 + 0.66
9.75 + 0.08(29) 9.75 + 0.08
2.79 + 0.06(29) 2.79 + 0.06
104.93 + 5.57(29> 104.98 + 5.36
15.00 + 0.84(29) 15.00 + 0.76
1.28 + 0.04(29) 1.28 + 0.04
12.26 + 0.88(29) 12.26 + 0.79
6.13 + 0.28(29) 6.13 + 0.26
101.90 + 6.19(29) 101.86 + 5.10
Moderate X + s.e.(n)
139.54 + 0.80(13) 139.54 0.77
1.99 + 0.-05(13) 1.99 T 0.05 4.45 + 0.06(13) 4.45 + 0.12 104.46 + 0.94(13) 104.46 + 0.99 9.71 + 0.10(13) 9.71 T 0.12 2.87 + 0.11(13) 2.87 T 0.09 99.92 + 8.27(13) 99.82 T 8.00 15.31 + 0.73(13) 15.31 + 1.13 1.25 + 0.07(13) 1.25 + 0.06 12.58 + 0.77(13) 12.58 T 1.19 6.55 + 0.28(13) 6.55 + 0.38 92.85 + 2.53(13) 92.94 T 7.62
p-value
0.2584 0.2633
0.7692 0.7745
0.8793 0.8800
0.33^8 0.3424
0.7753 0.7803
0.5099 0.5124
0.6191 0.5955
0.8209 0.8180
0.6945 0.6972
0.8225 0.8200
0.3758 0.3749
0.3445 0.3365
Table Severity of Chloracne versus Clinical Laboratory Findings
Mi 1d X + s.e. (n)
Total Protein (age adjusted)
7.76 + 0.11(29) 7.76 + 0.09
Albumin (age adjusted)
4.43 + 0.09(29) 4.43 + 0.08
Globulin (age adjusted)
3.33 + 0.12(29) 3.33 + 0.10
Albumin/Globulin (age adjusted)
1.39 + 0.07(29) 1.39 + 0.06
Total Bilirubin (age adjusted)
0.78 + 0.08(29) 0.78 + 0.07
Direct Bilirubin (age adjusted)
0.22 + 0.03(29) 0.22 + 0.03
SGOT (age adjusted)
34.83 + 2.37(29) 34.82 + 2.38
SGPT (age adjusted)
43.17 + 2.58(29) 43.16 + 2.40
GGTP (age adjusted)
18.64 + 2.57(28) 18.61 + 2.66
Alkaline Phosphatase 30.24 + 1.98(29)
(age adjusted)
30.24 + 1.78
LDH (age adjusted)
179.48 + 4.31(29) 179.50 + 5.76
Moderate
x :L s ,e.(n)
7.48 + 0.08(13) 7.48 7 0.14 4.29 + 0.08(13) 4.29 7 0.12 3.18 + 0.08(13) 3.19 7 0.16 1.36 + 0.05(13) 1.36 7 0.09 0.58 + 0.06(13) 0.58 7 0.11 0.15 + 0.01(13) 0.15 7 0.04 26.15 + 3.46(13) 26.16 + 3.56 32.54 + 3.07(13) 32.57 7 3.58 20.38 + 4.39(13) 20.46 7 3.91 30.38 + 1.65(13) 30.39 7 2.66 186.85 + 12.15(13) 186.80 7 8.60
p-value
0.0967 0.0999
0.3354 0.3403
0.4487 0.454c,0 0.7562 0.7534
0.1493 0.1523
0.1891 0.1929
0.0472 0.0500
0.0196 0.0186
0.7194 0.6972
0.9641 0.9619
0.4790 0.4848
C26637
Table Severity of Chloracne versus Clinical Laboratory Findings
Mild X :t s -e.(n)
WBC Cage adjusted)
7.43 + 0.31(27) 7.44 7 0.33
RBC (age adjusted)
5.14 + ' 0.06(27) 5.14 7 0.06
HGB (age adjusted)
15.64 + 0.25(27) 15.64 7 0.22
HCT (age adjusted)
MCV 1 (age adjusted)
47.47 + 0.68(27) 47.48 7 0.60 92.44 + 1.05(27) 92.45 7 0.96
MCH (age adjusted)
30.47 + 0.43(27) 30.47 7 0.38
MCHC
32.93 + 0.15(27)
(age adjusted) ' 32.93 7 0.15
Moderate
X : s.e.(n)
6.98 + 0.60(13) 6.96 + 0.48
5.05 + 0.06(13) 5.05 + 0.08
15.72 + 0.23(13) 15.72 + 0.32
47.62 + 0.66(13) 47.59 + 0.87
94.27 + 1.01(13) 94.25 + 1.38
31.12 + 0.35(13) 31.12 + 0.55
33.03 + 0.21(13) 33.03 + 0.21
p-value
0.4569 0.4244
0.4048 0.388i8 0.8385 0.8566
0.8942 0.9158
0.2823 0.2910
0.3272 0.3367
0.6970 0.6988
c 2-36 3y
Table Severity of Chloracne versus Clinical Laboratory Findings
Mild X + s.e. (n)
Poly (%) Cage adjusted)
Lymphocytes (%) (age adjusted)
Monocytes (%) age adjusted)
Eosinophils (%) (age adjusted)
Basophils {%) (age adjusted)
59,45 + 59.45 T
30.60 + 30.59 +
6.85 + 6.85 7
2.25 + 2.25 +
0.86 + 0.86 +
1.57(27) 1.48
1.42(27) 1.37
0.42(27) 0.45
0.26(27) 0.23
0.12(27) 0.10
Moderate
X + 5-e. (n)
60.22 + 1.78(13) 60.20 + 2.14
29.12 + 1.77(13) 29.14 + 1.98
7.99 + 0.75(13) 7.98 + 0.66
2.12 + 0.25(13) 2.12 + 0.33
0.55 + '0.09(13) 0.55 + 0.15
p-value
0.7675 0.7760
0.5412 0.5519 0.1600 0.1651
V
0.7413 0.7566
0.0997 0.1029
Poly (Abs) (age adjusted)
Lymph (Abs) (age adjusted)
Mono (Abs) (age adjusted)
Eos (Abs) (age adjusted)
Baso (Abs) (age adjusted)
4461.56 + 252.94(27) 4466.21 + 275.49
2239.11 + 122.46(27) 2239.96 + 115.05
498.07 + 28.90(27) 498.80 + 34.22
167.00 + 19.84(27) 166.90 + 17.11
62.07 + 7.73(27) 62.13 7 6.87
4288.00 + 485.21(13) 4278.32 + 397.05 1960.23 + 136.02(13) 1958.47 7 165.81
553.69 + 68.17(13) 552.18 7 49.32 135.69 + 11.04(13) 135.91 + 24.66
37.38 + 6.27(13) 37.26 7 9.90
0.7277 0.6997
0.1725 0.1714
0.3807 0.3796
0.2994 0.3086
0.0467 0.0461
C2663
Table Severity of Chloracne versus Clinical Laboratory Findings
Mild X + s,>e. (n)
Moderate X + s.e.(n)
p-vaT ue
Total Lipids (gm/dl) Cage adjusted)
Cholesterol (mg/dl) (age adjusted)
Triglyceride (mg/dl) (age adjusted)
Total Cholesterol (mg/dl) (age adjusted)
C-HDL (mg/dl) (age adjusted)
C-LDL (mg/dl) (age adjusted)
C-VLDL (mg/dl) (age adjusted)
0.69 + 0.03(28) 0.69 + 0.03
239.79 + 12.28(29) 239.70 + 11.16
215.10 + 20.93(29) 215.05 + 19.19
232.36 + 10.95(28) 232.52 + 9.76
38.29 + 2.73(28) 38.26 + 3.15
159.07 + 10.30(28) 159.24 + 9.32
34.79 + 2.92(28) 34.81 T 2.98
0.62 + 0.03(13) 0.62 + 0.04
239.62 + 14.61(13) 239.82 + 16.67
164.85 + 20.44(13) 164.96 + 28.66
236.46 + 11.76(13) 236.12 + 14.32
47.85 + 5.74(13) 47.89 + 4.63
158.77 + 12.50(13) 158.41 + 13.68
34.23 + 4.55(13) 34.18 + 4.38
0.1749 0.1600
0.9932 0.9950
0.1500 0.1544
0.8209 0.8366
0.0944 0.0937
0.9862 0.9601
0.9169 0.9069
C26630
Table Severity of Chloracne versus Clinical Laboratory Findings
Mild X + s.e.(n)
PH (age adjusted)
Specific Gravity (age adjusted)
5.29 5.28
+ +
1.0226 + 1.0226 +
0.10 (28) 0.10
0.0012 (28) 0.0012
Moderate J + s.e.(n)
p-value
5.23 5.23
1.0206 + 1.0206 +
1+1 +
0. 12 (13) 0.14
0.0018 (13) 0.0017
0.7485 0.7593
0.3498 0.3464
C2S691
Table
Severity of Chloracne versus Clinical Laboratory Findings
Blood Reference Range Units
Sodium(mmol/L)
134.00 - 146.00
Magnesium{meg/L)
< 1.60 1.60 - 2.20 > 2.20
Potassium(mmol/L)
3.50 - 5.50 > 5.50
Chloride(mmol/L)
< 96.00 96.00 - 110.00 > 110.00
Calcium(mg/dL)
< 8.80 8.80 - 10.80
Phosphorus(mg/dL)
2.00 - 4.70
Iron(ug/dL)
< 45.00 45.00 - 200.00 > 200.00
Mild
#%
Moderate #%
29 100.00
13 100.00
1 3.45
25 86.21 3 10.34
0 0.00
11 84.62 2 15.38
29 100.00 0 0.00
13 100.00 0 0.00
0 0.00
29 100.00 0 0.00
0
13 -0
0.00 100.00
0.00
1 3.45 28 96.55
0 0.00 13 100.00
29 100.00
13 100.00
0 0.00 29 100.00
0 0.00
0 0.00
13 100.00 0 0.00
p-value 0.7253
1.0000
C2S692
Table
Severity of Chloracne versus Clinical Laboratory Findings
Blood Reference Range Units
BUN(mg/dL) < 6.00 6.00 - 25.00 > 25.00 CreatinineCmg/dL)
0.50 - 1.70 BUN/Creatinine Ratio 3.57 - 25.45 Uric Acid(mg/dL) 2.50 - 8.50 > 8.50
Mild #%
Moderate #%
1 3.45 27 93.10
1 3.45
0 0.00
13 100.00 0 0.00
29 100.00 !
29 100.00
13 100.00 13 100.00
26 89.66 3 10.34
12 92.31 1 7.69
p-value ii.
0.6246 .''
1.0000
C2S69J
Table
Severity of Chloracne versus Clinical Laboratory Findings
Blood Reference Range Units
Glucose(mg/dL)
65.00 - 130.00 > 130.00
Total Protein(gm/gL) 6.60 - 8.90
Albuminfgm/dL)
< 3.60 3.60 - 5.20 > 5.20
Globulin(gm/dL)
1.90 - 3.70 > 3.70
Albumin/Globulin Ratio
0.46 - 2.63
Total Bilirubin(mg/dL)
0.10 - 1.70 > 1.70
Direct Bilirubin(mg/dL)
0.00 - 0.30 > 0.30
Transaminase, SG0CIU/L)
1.00 - 50.00 . > 50.00
Mild %
Moderate %
28 96.55 1 3.45
13' 100.00 0 0.00
29 100.00
1 3.45 27 93.10
1 3.45
13 100.00
-
0 0.00 13 100.00
0 0.00
23 79.31 6 20.69
12 92.31 1 7.69
29 100.00
13 100.00
27 93.10 2 6.90
13 100.00 0 0.00
27 93.10 2 6.90
13 100.00 0 0.00
27 93.10 2 6.90
12 92.13 1 7.69
p-value
1.0000
0.6245
-
0.4049
1.0000 1.0000
1.0000
C236d'L
Table
Severity of Chloracne versus Clinical Laboratory Findings
Blood Reference Range Units
Mild TJTl %
Transaminase, SGPCIU/L)
1.00 - 70.00 > 70.00
27 93.10 2 6.90
G-glutamyl Transpeptidase(U/L)
1.00 - 70.00 > 70.00
28 100.00 0 0.00
Alkaline Phosphatase(IU/L)
10.00 - 50.00 > 50.00
27 93.10 2 6.90
LOH(IU/L)
90.00 - 250.00 > 250.00
29 100.00 0 0.00
Moderate tirf %
13 100.00 0 0.00
13 100.00 0 0.00
13 100.00 0 0.00
12 92.31 1 7.69
p-value
1.0000 ___ ]_
.-' 1.0000
0.3095
c 2S6`95
Table Severity of Chloracne versus Clinical Laboratory Findings
Blood Reference Range Units
CBC
WBC(thousand/cu.mm.)
4.00 - 11.60 > 11.60
Differential Polys(percent)
< 42.0 42.0 - 81.0 > 81.0
Lymphocytes(percent)
10.0 - 47.0 > 47.0
Monocytes(percent)
0.0 - 10.0 > 10.0 EosinophiIs(percent)
0.0 - 8.0
BasophiIs(percent)
0.0 - 2.0 > 2.0
Mi Id
%
Moderate #%
27 100.00 0 0.00
12 92.31 1 7.69
0 0.00 27 100.00
0 0.00
0 0.00
13 100.00 0 0.00
27 100.00 0 0.00
13 100.00 0 0.00
25 92.59 2 7.41
10 76.92 3 23.08
27 100.00
13 100.00
26 96.30 1 3.70
13 100.00 0 0.00
p-value 0.3250
0.3065 1.0000
C25690-
Table Severity of Chloracne versus Clinical Laboratory Findings
Blood Reference Range Units
Mild
%
CBC
Differential Absolute Values(cells/cu.mm.)
Neutrophils
1650 - 8330 > 8330
27 100.00 0 0.00
Lymphocytes
< 1049
1049 - 3581 > 3581
0 0.00 26 96.30
1 3.70
Monocytes
61 - 929 > 929
27 100.00 0 0.00
Eosinophils
< 40 40 - 423
1 3.70 26 96.30
Basophils
< 10 10 - 148 > 148
0 0.00
26 96.30 1 3.70
Moderate l%
12 92.31 1 7.69
0 0.00 13 100.00 0 0.00
12 92.31 1 7.69
0 0.00 13 100.00
0 0.00 13 100.00 0 0.00
p-value
0.3250 1
1.0000 O'.3250 1.0000 1.0000
C5S69V
Table Severity of Chloracne versus Clinical Laboratory Findings
Blood Reference Range Units
Total Lipids(gm/dL)
0.30 - 1.00 > 1.00
Cholesterol(mg/dL)
< 125 125 - 300 > 300
Tri glyceride(mg/dL)
50 - 200 > 200
Total Cholesterol(mg/dL)
< 125 125 - 300 > 300
C-HDL(mg/dL)
< 30 30 - 75 > 75
C-LDL(mg/dL)
< 60 60 - 185 > 185
C-VLDL(mg/dL)
0.0 - 40.0 > 40
Mild #%
Moderate #%
p-value
27 96.43 1 3.57
13 100.00 0 . 0.00
0.6829
1 3.45 23 79.31
5 17.24
0 0.00 10 76.92
3 23.08
0.7352
1
16 55.17 13 44.83
9 69.23 4 30.77
0.5Q46
1 3.57 22 78.57
5 17.86
0 0.00 i
12 92.31 1 7.69
0.5238
8 28.57 20 71.43
0 0.00
1 7.69 11 84.62
1 7.69
0.1274
1 3.57
20 71.43 7 25.00
0 0.00
9 69.23 4 30.77
0.7481
18 64.29 10 35.71
8 61.54 5 38.46
1.0000
C23S98
Table Severity of Chloracne versus Clinical Laboratory Findings
Urine Reference Range Units
Appearance
Clear
Specific Gravity
1.008 - 1.036
Acetone
Negative 1+
Albumin
Negative
Glucose
Negative 2+
Blood
Negative
"WBCp Negative 0-2 2-5 5-10
R'B'C Negative 0-2
Casts
Negative
Bacteria
None Slight Moderate
Mild #%
Moderate #%
28 100.00
13 100.00
28 100.00
13 100.00
28 100.00 0 0.00
13 100.00 0 0.00
28 100.00
13 100.00
27 96.43 1 3.57
13 100.00 0 0.00
28 100.00
13 100.00
22 78.57
2 7.14 3 10.71 1 3.57
10 76.92 1 7.69
2 15.38 0 0.00
28 100.00 0 0.00
13 100.00 0 0.00
28 100.00
13 100.00
27 96.43 0 0.00
1 3.57
11 84.62 2 15.38 0 0.00
p-value
____ 1.0000 0.75<p<0.90
0.0860
H^ 0 G QMfj
r
y ./
Table
Severity of Chloracne versus Clinical Laboratory Findings
Urine Reference Range Units
Crystals
None Uric Acid Calcium Oxalate
Yeast
Negative PH
5 6 7
Mild #t
Moderate %
26 92.86 ` 13 100.00
0 0.00
0 0.00
2 7.14
0 0.00
28 100.00
21 75.00 6 21.43 1 3.57
13 100.00
10 76.92 3 23.08 0 0.00
p-value
1.0000
.
-- *-- 0.7868
i
C2S70n