Document 15dd3ENvd7L9307Rx4kDYGOzj

July Q, 1964 Msdtitl Dspartaent apNlblDd Div. oT Kon. Med. Hoogovena an dtaalfsbrieieen 14 Mulden, Motherland* Qentleasnt I have bMn asked to forward toxicity and aafo handling information on our fir* resistant hydraulic fluid. FriyOdrTaul 1*^>0. -^>a- ^ rf /W ^ . W l. k~ />*, The anlasl toxielty report -on Sydrsul 190 indioates that ia^practieally innosuous Khan fad orally to mtSslnos tha an!wale survived single doaas of B&.5 grows par kilogram with lots of appatita and severe diarrhea as tha only tootle offsets, tha fluid apparently la not absorbed through tha unbroken shin of rabbits since this species survived doses up to 9.5 area* par kilogxew of body weight. Zn rabbit skin and aye irritation studies, fydraul 190 was no wore irritating than a 10 par eent soap solution tasted similarly, Zn aaaas where wortasan have soddentally splashed or rubbtd fydraul 150 into tha ayes, there has bean severe Min out of proportion to tha degree of irrita tion. This la similar to the situation with most synthetic fluids aa wall as with aany light patrolaun Hi. fhyelelana have used a 0.5 per amt pontooalns solution and ophthalmic aortiaooa aaatata solution to raiiava irritation. In aauta vapor inhalation studies, rata survived a six hour exposure to an atmosphere saturated with fydraul 150 vapors at room tonpara hire. I would not expect that significant vapor aoneentrations would be liberated at teaparsturea up to 100F 1 Baaed an tha aniaal toaialty data and handling enperlanse, our label includes ths following praaautlonary Infocaationt __ rfMlSki OSW 01858? ........ j>~ STLCOPCB4005131 Modioal Bnvtaioti IrMJbtn^ July 6, I9W fact s cAoricaii comma chlcbimatkd otbbocmiiiom Avoid prolongod broathing of vapors or aists. Avoid sontoot with oyoa or prolonged sontact Kith akin. If akin sootast ooours, roaovo by washing with soap and Motor, Following aya sontoot, flush with watar. If olothing booo-- sookod with fluid, laundor boforo wotrlng again. If I oan bo of any furthor aaolatoooo, ploaao do not hositato to lot ao know. Vary truly yours. A. Snoot Solly, M.JD. Hsdloal Piroctor MKiajb oat P,F,C Farry ~ Monsanto, Mruaaols MF,A. troap - Monsanto, fivussola blccto&lo Smith - St L DSW 018588 STLCOPCB4005132