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lo BIOSEARCH, INC. p.o. box 8598 philadelphia, pennsylvania 19101 telephone: (215) 848-4499 eSumbimtittteeddttoo:r Material: Sample Received: Date of Report: Test: Shject of Test: procesure: Results: Conclusion: - 3HIMnA CCaonmtpaarny 55101 3M Company - T-1388 November 28, 1975 March k, 1976 heute Oral Toxicity Rats To study the acute oral toxicity In rats of the subject material. FaSonhuaerr3m0ga0rnocuoipmissvtoeafrre5Setmmrapallienoyweedi5gihfneimntaghliesbeatslewebedieynn.o"20r8aTthse of the Tats were dapr ved of food but not carer for 24 hours prior to dosing. Each animal was mwTeehaeingsheexdpoeFranamdesnydtroiasnlegde.mabtayenrddiiarolesctiInntgaod.mneithenedi.lsets.rtaotmiaocnh obfy The sample was dosed as a 25% w/v suspension In corn oil. The following dosage levels were administered: 25 ie 0.63 gm/kg 1.25 gm/kg 5.0 g/kg Following adninistration the animals were mGaTarlaytlisoaowlwbeasdiretsrifovonoao:btdsieoarnnvdepdweartifeoordr saadlugrnilsnigboiwfthuitmcohfxoirtcimeteyh:eetnh1de4 See Table 1. : The subject material when studied in male & female albino rats has an acute oral Lg, of less than 0.63 g/kg. BairrtectL.sr Sbrict? VHD. pho, 005799 { | aS Hotorlali Tote 1 Acute Oral Toxicity 34 Conpany - T1388, 3 a 25% w/v suspension in corn oll. DLeovsealge sulky HofusbAneirmals Doses 1234567K8orDt5aaytis0ti0es 10 12 03 Ww DeToatdal Vhbws 063 Smiles 11100000000000 3 065 sfemles 12000000000000 3 135 smiles 22100000000000 5 135 Sfemles 20030000000000 5 25 Smiles 32000000000000 5 25 sfemles 41000000000000 5 50 Smiles 50000000000000 5 50 Sfemles 50000000000000 5 The Logo is less than 0.63 parks. TSoutravlived 1hbas 2 2