Document 150nzxZ4xEaRN41QzKaZqV95m

TV 4 OFFICIAL FILE COPY *Wf AUTM D TCMF CALL U. Q rice Caption Mr. Robert Herrick Pranklin-Hahneesnn lastituts ISOS Sac* St. Boos 903 Philadelphia, Pa. 19102 19 August 1974 tear Mr. Herrick* Ms ar* writing to you to ask if you would b* iatarssted la doing a study *or our Cospany oa ths proble* of aabeatosia la oil rsfiasxy workers. la this study, which would b* carried out ia five rsfiasrias b*longiag to fiwe different oil companies (who ar* also iatarssted ia participating ia this study) mw would want to know ths nuebera of people suffering frosi asbestos!* whether they have ewer worked with asbestos or whether they have just been exposed to asbestos as a possible air pollutant. A copy of a proposed protocol for this study is enclosed for your rewiew. This study would cower a fiwe-year period. If you would consider doing this study for as, we would appreciate say ideas that you would wish to add to ths protocol and an estimate of ths oost iawolwed. The othsr oil particpsting ooapaaiss would also share ths cost of ths study. We are looking forward to hearing fros you oa this natter. Tours truly, HAStjd Enclosure H.A. Sinclairs, M.D. Medical Director 05613 4*7383 ' f-' w DRAFT PROTOCOL FOR A FT.VF YFA'.I CT'.JDY OF T!!L PROW .PM OF asbfotcafc::';:;y on, k i:y workkrs t;j FtVE RKFiRKFr- ; a:::\p fy fivf. DTFi; 'liCTIT CORPAFATto:;.c 1. For purposes of this study all prospective participants should be studied yearly for a minimum of 5 years, a minimum of 3,000 parsons are needed. 2. The participants should be all refinery workers under age 55 at the onset of the study in the participating oil refineries. (This assumes a usual retirement age of 60 or 62 years.) 3. The proposed study will include: a) a multiple choice history completed by the participant to .include questions concerning: 1. exertional dyspnea w* interval laicCuiOuS 3. smoking history (number of years and amounts) It. Previous industrial and Geographic exposure to asbestosis or other dusty inhalants'. The history is to be reviewed by a physician. A complete physical examination will then be performed with special emphasis on the chest, Standardised pulmonary function studies on a Fuimoncr Vital Capacity FE7, and a lV % 17" chest x-ray; A? + Lateral will be done. Any person found to have an abnormal chest x-ray and/or a vital capacity less than 85w of the predicted maximum expiratory flew rate, should be examined by a pulmonary specialist for diagnosis and possible recommended care. All chest : Wj * w. U ` wo :. 05614 447384 readings and reviewing each other's reports. All subjects havinG a diagnosis of asbestosis should have an x-ray every four months instead of yearly, tp observe the progression of the disease. The overall study will be monitored by a university-connected pulmonary specialist, data collected, tabulated and a report written. The study's cost will be underwritten by the participating refineries' parent organization. N. B. 1. Controls would be refinery office workers and other nonmanual workers in a refinery population. 2. Refinery participants would be geographically dispersed. 3. Data collection systems will conform with computer programs. HAS/maw 2/5/7Ji 05615 447385