Document 0qYvGbX9aeJL1J6xkob0vwyNb

0 P Y R. L. Gol t z New Yor k J. T. Beckwi t h Shar on, Mass. Sci ent i f i c Pr oduct s, I nc Beacon Fal l s, Conn. Apr i l H, 194- 6 Dear Roy: Yest er day Ben Cr ams and I cal l ed on Dr . of t he above concer n, dur i ng whi ch t i me we l ear ned mor e def i ni t el y t he manner i n whi ch TEL i s t o be used. The pr ocess i s as f ol l ows- The r eact i on chamber wi l l be pl aced under a f ume hood whi ch i s wel l vent i l at ed. Al l j oi nt s connect i ng f l asks t o t he r eact i on appar at us wi l l be mer cur y seal ed, except t he upper condenser j oi nt whi ch wi l l be connect ed t o t he exhaust chamber of t he f ume hood. TEL and mer cur y bi chl or i de ar e r eact ed i n et hyl acet at e sol ut i on i n whi ch t he r at i o of sol i ds t o l i qui ds i s 10 t o 1. The r eact i on wi l l be compl et e on t he TEL. At compl et i on of pr i mar y r eact i on of mer cur y and l ead, acet i c aci d i s added t o compl et e et hyl mer cur i c acet at e cycl e, af t er whi ch excess acet i c aci d i s exact l y neut r al i zed wi t h deci nor mal al cohol i c caust i c soda. The r esul t i ng pr oduct i s washed on t he f i l t er t y suct i on. , The et hyl mer cur i c acet at e i s i sol at ed i n t he usual manner . The sol i d r esi due whi ch wi l l consi st of l ead chl or i de wi t h t r aces of l ead acet at e, i f r easonabl y pur e, wi l l be' sal vaged f or use i n ot her manuf act ur i ng pr ocesses, or ot her wi se pr oper l y bur ned on t he pr emi ses i n a pr i vat e i nci ner at or . The et hyl mer cur i c acet at e i s t he pr i mar y r eagent sought f or , and wi l l be used f or f ur t her pr ocessi ng wi t h pr ot ei ns t o ar r i ve at a chemot her apeut i c agent . ' Dr . f f l j ^f e i s wi l l i ng t o submi t sampl es of t he et hyl mer cur i c acet f i r t ^t o Dr . Kehoe f or anal ysi s. Vei y t r uLy your s, / s/ J. T. Beckwi t h 0009376