Document 0qNq7E3oxwV5x4EXxoY3g5B2V

Interim Report 1 (July 1, 1995) Update of Mortality Among Vinyl Chloride Workers I. Study Staffing At CMA's request, and in anticipation of a February 1, 1995 study start date. Applied Epidemiology, Inc., retained the data management services (50%) of Mr. Noess of SoftWhere, Inc., and recruited and hired (50%) another epidemiologist. Rose Luippold, M.S. II. Data Acquisition Applied Epidemiology, Inc. received 81 boxes from ENSR in early May. Because no inventory list accompanied any of the boxes, we examined the contents of all boxes, consolidated and transferred records to new boxes, created an inventory of contents, and moved the boxes to our storage facility. A copy of the inventory of the boxes we are currently storing is attached. Nineteen of the 81 boxes contained data from an unrelated study. These will be shipped back to ENSR in the near future. No data tapes, disks or files have been received by Applied Epidemiology, Inc. as of the date of this report. This has prevented us from making any progress toward construction of the relational database for the study, conducting the cohort verification, and replication of the results obtained by the previous contractor. No death certificates have been received from ENSR as of the date of this report. III. NDI Application Application for search services by the National Center for Health Statistics, National Death Index, has been prepared by Dr. Ramlow, with minor assistance from Applied Epidemiology, Inc., and submitted on behalf of CMA. IV. State Confidentiality Agreements Applied Epidemiology, Inc., has completed confidentiality agreement forms for several states, either sent directly to us by the states or via CMA. In May and June, we completed confidentiality agreements with state departments of vital statistics for Alabama, Colorado, Florida, Hawaii, Maine, Montana, New Hampshire, Pennsylvania and Rhode Island. All requests received have been processed within 1 to 3 days of receipt. CMA 112881 Interim Report 1 (July l, 1995), p. 2 V. Communication With Vinvl Panel In May, we sent letters to the members of the CMA Vinyl Chloride Research Panel. The letter explained that, once we have identified study subjects who were known to be alive at completion of the previous update (i.e., as of 12/31/82), we will be asking for their assistance in identifying the employment and vital status of study participants. We are unable to proceed further with this step until the data needed to prepare lists of employees by plant are made available to us. VI. Protocol Development and Review A detailed protocol for the study has been drafted according to the Guidelines for Good Epidemiology Practices. Copies of this draft protocol have been sent to our external reviewers, Drs. Harvey Checkoway and Kathy Hammond, for comments. We expect to receive their comments, revise the document, and submit an updated protocol to CMA by August 1, 1995, for review and comment. VII. Development of Rate-Weighting Program Applied Epidemiology, Inc., in conjunction with SoftWhere, Inc., has begun developing a rate weighting computer program called ProRate. At this stage we are capturing national rates from vital status records (books) for the earliest study years, and have applied for approval to purchase the Compressed Mortality Files (CMF) from the National Center for Health Statistics (causespecific mortality rates from 1968 through 1993). CMA 112882 Inventory of boxes received from ENSR - May 11, 1995 Box Subject ID numbers 1 6087-6239 1 4386-4474 1 2198-2283 2 9031-9192 3 2284-2360 4 2361-2525 5 5264-5489 5 3855-3975 6 1-58 6 3759-3854 6 4475-4600 7 4601-4856 8 509-575 8 2889-3095 9 1639-1889 10 1890-2099 11 2100-2197 11 2866-2888 11 484-508 12 8462-8695 13 8698-8967 14 3976-4328 15 125-174 15 4329-4385 15 175-308 Plant Current Company Location 1 Air Products Calvert City, KY 2 Air Products Pensacola, FL 3 Allied* LA 4 5 Borden Chemicals Illiopolis, IL 6 Borden Chemicals Leominster, MA 6 Borden Chemicals Leominster, MA 7 Conoco Chemicals Aberdeen, MS 8 9 Conoco Chemicals Westlake, LA 10 Dow Chemical Ontario, CANADA 11 Dow Chemical Plaquemine, LA- 12 Dow Chemical Midland, MI 12 Dow Chemical Midland, MI 13 Dow Chemical-Oyster Freeport, TX 14 Dow Chemical-Texas Freeport, TX 15 Ethyl Corporation Baton Rouge, LA 15 Ethyl Corporation Baton Rouge, LA 15 Ethyl Corporation Baton Rouge, LA 16 Ethyl Corporation Houston, TX 17 Occidental Chemical MD 18 Occidental Chemical Pottsdown, PA 18 Occidental Chemical Pottsdown, PA 19 Goodyear Niagara Falls, NY 20 21 Borden Petrochemical Geismar, LA 22 23 PPG* Lake Charles, LA 24 Stauffer* Delaware City, DE Box Subject ID numbers 16 5490-5660 17 5662-5805 18 9193-9379 19 9380-9508 20 9510-9799 21 9801-9999 22 10,001-10,199 23 10,200-10,319 24 3469-3758 25 3133-3468 26 5806-6086 27 1018-1165 28 1167-1408 29 1411-1638 30 4857-5037 30 576-669 31 6240-6574 32 6575-6876 33 6878-7172 34 7173-7518 35 7519-7775 36 7776-7999 37 8000-8206 38 8207-8461 39 UNKNOWN 30 670-737 40 2526-2763 41 738-1017 Plant Current Company 25 Union Carbide 25 Union Carbide 25 Union Carbide 25 Union Carbide 25 Union Carbide 25 Union Carbide 25 Union Carbide 25 Union Carbide 26 Union Carbide 27 Uniroyal Chemical 28 29 BF Goodrich 30 BF Goodrich 30 BF Goodrich 30 BF Goodrich 31 BF Goodrich 32 BF Goodrich 33 BF Goodrich 33 BF Goodrich 33 BF Goodrich 33 BF Goodrich 33 BF Goodrich 33 BF Goodrich 33 BF Goodrich 33 BF Goodrich 33 , BF Goodrich 34 BF Goodrich 35 36 BF Goodrich Tech 37 Diamond Shamrock Location S. Charleston, WV S. Charleston, WV S, Charleston, WV S. Charleston, WV S. Charleston, WV S. Charleston, WV S. Charleston, WV S. Charleston, WV Texas City, TX Painesville, OH Calvert City, KY Avon Lake, OH Avon Lake, OH Avon Lake, OH Henry, IL Long Beach, CA Louisville, KY Louisville, KY Louisville, KY Louisville, KY Louisville, KY Louisville, KY Louisville, KY Louisville, KY Louisville, KY Niagara Falls, NY Avon Lake, OH Deer Park, TX Box Subject ID numbers 40 413-483 42 5038-5263 43 2764-2865 44 59-124; 3096-3132 44 309-412 44 8970-9030 Plant 38 39 40 41 42 43 Current Company Diamond Shamrock Monsanto Monsanto Tenneco Chemicals Tenneco Chemicals Tenneco Chemicals Location DE Indian Orchard, MA Texas City, TX Burlington, NJ Flemington, NJ Pasadena, TX OTHER STUDY?? 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 3 Illinois 3 Illinois 3 Illinois 3 Illinois 3 Illinois 8 Cleveland, OH 12 New Jersey 13 California 15 DeSoto Inc. Greeensboro, NC 16 Du Pont Parlin, NJ 16 Du Pont Parlin, NJ 17 Philadelphia F & F Philadelphia, PA 17 Philadelphia F & F Philadelphia, PA 17 Philadelphia, PA 17 Philadelphia, PA 18 Toledo Finishes Toledo, OH 19 Pontiac Varnishes Pontiac, MI 21 California 32 Chicago, IL CMA 112885 Box VCM STUDY 64 Employment verification 65 Employment verification 66 Computer keypunch cards 67 Employment verification print outs for leuk. study 68 Computer print outs SAS logs 69 Employee Health Testing Records 70 Employment records deceased employees 71 Employment records deceased employees 72 Employment records deceased employees Notes UCC UCC Box 1 of 4 Box 2 of 4 Box 3 of 4 S. Charleston, WV S. Charleston, WV * Did not participate in employment history/vital status update through 1982 CMA112886