Document 0geB3N4gZEV29qEJgxGYD05JM

REPRODUCED at t h e n a tio n al a r c h iv e s UNITED STATES ENVIRONMENTAL PROTECTION AGENCY f F B ^ 1976 fy y < e u'ic-f f4&' : v /c-T'?-'f c **f $jr rA T *( T # r Sy fesi-C-<\ T '/ } 7/-v />7 Mrs Carrie L. Hogue 10510 East Lynrose Street Temple City, California 91780 LQ f" - Of CM1 CM O rcUL-oDO. X j CD Dear Mrs. Hogue: This is In response to your letter of February 5, 1976, inquiring about the possibility of your father's cancer being caused by exposure to emissions from the vinyl chloride plants in Painesville, Ohio. We are truly sorry that both your father and h1s friend passed away as a result of cancer. From the history you communlcated to us* it appears that there is a possibility that your father's urogenital cancer, and your mother's miscarriage, may have resulted from your father's extended exposure to the emissions of the vinyl chloride plants, though it 1s hard for us to give you a definitive answer. nrL 3I _> C -- cn+J r" C O nCD "*ro~ *<QdJ EU U( OJX3) d \CtC (/> CM SZ. O O __i OO LI LI OU J Uu Currently, the Environmental Protection Agency (EPA) 1s involved 1n a continuing effort to establish emission levels for vinyl chloride and other ubiquitous pollutants which pose a threat to man and the environment. Hopefully, through EPA's efforts, there will be a substantial decrease in the number and severity of these harmful effects. I am sorry that we are unable to give you a concrete answer to your question. Hopefully, you can underst&id that we are unable to make such judgements with so little information available. Again, we wish to express our regret over your father's death. If I can be of any further assistance to you in the future, please feel free to contact me. Sincerely yours, Origin;?.?:, signed bys R o n?.\& b, Jmssl, Ph.lL Ronald E. Engel, Ph.D. Director Health Effects Division -F A F O R M 1020-1 O FFIC IAL FILE CO PY REPRODUCED AT THE NATIONAL ARCHIVES % g / s /I < ? 7, (f^y*'' CCp?A^tA^-Y.-XCp'' ' y^Y C'C *-- 9'7?0 S y /9 7 ^ y y . c ,,'i^c. n *7fs^2~-icY-t^ct--J',p /s yj''7/-'trW'Z^-t'i-''-c-g, ^~---'',,.-C-(,' C7.A' y% ^/' '/i--L-?,*--?% /(- '7 '- 7 7 z (_ y. ^ - y7p c v^7, ^ C~~Y'- C-^^' -'^ / ,? ./ y ..^ - L ^ t ,c/ ^ c X c // y x ^ CLe^ c y t c ^ ^ ^..y_ y y c~ c X b c^te y L - X / y y y _**. y I{ . . - c ' 7 yz^-Y^o ivt,t.- 7 % 7 , .. /s, / 9 S 3 y x,c*<^ts/ Y y * ^ 3 ^ - u ^ f . z ^ / c <h 7 . f A . ^ ; y ^ u r i ^ YY c ^ X ^ X u ^ l- X Cy.i Yz '~t^ JL X/i> ^tyL^^c c^y,y fr, j s* y tc<^ y y/tcr' yXcytL^^^ yC y. /CY^-aa* y,-<r~!Z'< -" yy^'U'^VL' --o-~t%s t //a. ,y y y i\^y\.yyJL / 4 ^ X ^ y^Y )^zo z^^/ /^V"3 v /9 f ycc'pyo^ J ^ ^ A ^ y j ^ X t y j U xrtpk^j^J^ ^ y,iyJA^ /fXs&y' yY ^^Ys /^Cl-?uo/// \ XyZy^ ~sYj-' (X,iX e e 1 / pLy^AC^,AX.^sC^zC/-7^'Vy' ///OUX-L'AP' .-Cm c ^ x ^ Y u y ^ rf? P^ftc-/ y^yviA^y yCj~-7xX-ri/ -^ ^JsJ'jY*~yX ~ A L c J -s REPRODUCED AT THE NATIONAL ARCHIVES ^"^y ^ v/ a ^ lX Z ~ y j u x t /m a , yiM-^yX. H ' u . r ' . / * x '"It' ^ Jz<(_^Xsz-` , Y " '. ^r' ^ . yC> y ypfs yt^C^XX ,$/(_,'\Lx~~' y^-'C'X^y. yC^ sS?J-'Z`t-&`b y*^ f>y .y.^~' /X?'7Ccy-- ,X-C^.-c-~~C<__.-/^ /' /'C-Z^.-C ^"XL'Cy^f. '9'i-^/ ^ lJ lC ^Cy `o' / lycy{~ `/^cy ^CCi-y/ci-c' y<xxcx_^x<-^^~ /C^tO Ct'trri<<LYC-t( ^^-c^ c-y (.- u / Y J &~<$i-z%/ / /lcl^ /b<z^Y?^cci^jy y '^yi-c ysC'cc Cl UslyZS ttcc cxf- /-fi REPRODUCED AT THE NATIONAL ARCHIVES UNITED STATES ENVi n AGENCY ot fc1 ^ (mj v ' f fbS: 4~ d? #;'f />// HtHommm TO : David Hawkins, Assistant Administrator Office of Air m Waste Banalement dody tte rn ste ln , Assistant Administrator Office of donerei1 Counsel FROM : Elizabeth L* Anderson, Executive Director Carcinogen Assessment Group SUBJECT: Clarification of Vinyl Chloride Itera on the Carcinogen Assessment Group Agenda In view of our discussion tins morning of the Carcinogen Assessment Group's current activities, 1 would like to clarify the status of the vinyl chloride agenda itera. The agency proposed amendments to the v in y l c h lo r id e standards 1n the Federal R e g is te r on dune 2, 1977. The w r itte n responses to the proposal are now oping re c e iv e d , ana th e O ff ic e o f A i r Q u a lity P la n n in g arm Standards (0AQ?$) m s asked the CAG to review the c a rc in o g e n e s is is su e s r a is e d by the respondents. The schedule f o r c P A 's a n a ly s is o f the responses Is c u rre n tly being worked out, out a p re lim in a ry estim ate by personnel in uApPS is th a t perhaps by January 1 1$78, z m CAG's a n a ly s is w i l l bo expected* A le t t e r c o n firm in g tu ts schedule is expect# sontlvse t h is week* cc: CAU GAG Chron RHcGaughy:1m :10/31/77;m 382$ SYMBOL. ^ SURNAME ^ D AT.S ^ Fm 13204 (12*70) CONCURENOE S OFFICIAL FILE COPY REPRODUCED AT THE NANAL ARCHiVES UNITED STATES ENV IN AGENCY mv a w? <tn 0 ^ ) \ A* - V v ( f A ^ n `ee/ r/t ^ "f j 7~ti# / /Of P ' A t ? A fkr&^t: O FJaV ^ 7A i u r / J - c^iC/et? s /T - SUBJECT: OKD Presentation afc Regional Administrator's Meeting FROM; Elizabeth I*. Anderson, Executive Director Carcinogen Assessment Group (RD-669) TO; Michael L. Hnstracci, Director Regional Services staff (RD-680) Attached is the Carcinogen Assessment Group Summary requested by your October 12, 1977, meaio. The additional information requested by your October 20th memo follows: 1. Mission: The Cancer Assessment Group- is a small group of senior scientists, with a liaison from The Matronal Cancer Institute, whose purpose is to advise the Administrator and Agency program officials on the health risks associated with the use of suspect carcinogens. The Carcinogen Assessment Group provides assessments on the oncogenic potential of suspect agents as well as an estimate of the potential cancer risk, should trie agent go unregulated. Hie CAG also provides advice and comment on proposed Agency regulations or guidelines which seek to reduce exposure to carcinogens. 2. Bacen t AccorapXishments s (a) The CAT was established in July, 1976 as a review group for all Agency decisions involving cancer risks, {i.e., K&fcer Quality, Water Supply, Air, Pesticides, Radiation and Toxics). (b) Twenty-three (23) preliminary reports have been prepared on the potential carcinogenicity of pesticides in the environment, which provided the basis for the pesticides office to issue Many Rebuttable Presumptions Against Registration (RPAR's). i I \ EPA Form 1320-1 (12-70) OFFICIAL FILE COPY REPRODUCED AT THE NATIONAL ARCHIVES UNITED STATES EN ION AG EN CY 2 {c) Fourteen {14) risk assessments were completed during FY '77. Chemicals such as Dihromochloropropane , Kepone, Coke Oven emissions , and Benzene were analyzed by the CAG. Many of these risk assessments have provided the impetus for regulatory action; for others these assessments have triggered the standard setting process. {d) The CAG established close working relationships with The National Cancer Institute {NCI), 'the National Center for Toxicological Research {NCT.R), and the National Institute for Environmental Health Sciences (NIEHS). These ties, as well as ties with major U.S. universities, assure the Agency of input and review by many of the top cancer experts in tiie country. {e) As part of its assistance to the Pesticide Re-Registration process, the CAG prepared a risk assessment on Chlordane/Beptachlor for use in the Agency's administrative concellation hearings. The CAG risk assessment was considered a major part of the EPA's case during the hearings. The CAG document was subsequently supported in a review by the National Academy of Science. (f) During FY 'll, the CAG provided guidance and comment on several proposed Agency standards and regulations involving carcinogenicity. Specifically, the CAG reviewed and made recommendations on proposed Pesticide Testing Protocols, Guidelines on Transuranium Elements, Vinyl Chloride Standards, and the Drinking Water Standards for Haloforms. {g) The CAG is currently participating in the Interagency Regulatory Liaison Group a cooperative effort by Federal regulatory agencies to base their regulations on some shared scientific principles. The CAG representative has been asked to chair the Sub-Committee on Criteria for Determining Carcinogenicity. 3. Regionally Related Projects; {a) The CAG prepared a health risk assessment due to a Trichloro ethylene discharge for Region I. (b) The CAG prepared a risk assessment and commented on a proposed enforcement action resulting from Vinyl Chloride emissions from a plant in Region IX. (c) The CAG analyzed data and reported on the potential health risk involved form contamination of Philadelphia wastewater for Region III. SYMBOL ^1 surnamey {d) Nitrosamine discharge levels were evaluated for their puotential'health 'risk-'at the request of-Region -Vi----------- CONCURENCES J -- ...The.A.., t.preparing..a .f u l l .anysl& .Q O he,, possible cancer ris ;k from the uses of HfB' s for Re<ion XI. DAT.E 1 EPA Form 1320-1 (12-70) OFFICIAL FILE COPV REPRODUCED AT THE NATIONAL ARCHIVES UNITED STATES ENV >N AG EN CY 3 4. Biographical Sketch ~ Chairman, Carcinogen Assessment Group o .Roy E. Albert o Chairman, CAG Deputy Director, School of Environmental Health NYU Medical Center, NY University .o M.D. form New York University College of Medicine in 1946 o Chief Health Advisor to the Administrator, EPA July 1976 to present. o D M for Health and Ecological Effects, Office of Research and Development, EPA - July 1975 to 1976 See attached Curricalum Vitae cc: CAG/Reading CAG/Subject CRU / B. Anderson RD689:K.Libby:lb:X53039:WSM3700:11877 SYMBOL SURNAME ^ DATE ^ EPA Form 132.0.1 (12-70) CONCURENOES OFFICIAL FILE COPT