Document 0gJg547w5Oe9pN2NjOrjJ3BbM

CMza CHEMICAL MANUFACTURERS ASSOCIATION Dear Health and Safety Contacts of CMA Member Firms Dear Contact: Subject: Review of Draft CMA Guidelines for the Preparation of Material Safety Data Sheets Since November, 1968, CMA has been developing a guideline for the preparation of material safety data sheets (MSDSs). The enclosed draft is being circulated to all CMA member companies for review and comment by January 10, 1990. The guideline is the first phase of a two-phase project to develop a consensus standard on MSDSs. Upon approval of the guideline by CMA, the second phase of the project will be initiated through the American National Standards Institute (ANSI), with CMA serving as the Secretariat. This project was initiated as a result of concern expressed by CMA's Board of Directors about a number of factors impacting the MSDS. First, passage of Title III of the Superfund Amendments and Reauthorization Act of 1986, the amendment of the OSHA Hazard Communication Standard, and the proliferation of state right-to-know laws have all expanded the audiences for MSDSs beyond the health and safety professionals and industrial workers originally intended to be covered. These new audiences include fire departments, emergency responders, state and local emergency response planning groups, and community members. Secondly, many activities of the federal government, the states, standard setting organizations, the international community, and other industry organizations were focusing on the needs of these new audiences. Developing a standard MSDS format, restricting or expanding the content of MSDSs, and supplementing the MSDS with other communication vehicles were being considered at the time. The chemical industry ultimately decided to take the lead in promoting effective MSDSs. Toward this end, the enclosed draft guideline focuses on MSDS content, consistency and communicability. The guideline also recommends inclusion of an emergency overview in the MSDS to respond to the needs of new audiences. While the guideline recommends some new approaches to preparing MSDSs, which may represent a departure from current practices, we believe the guideline is responsive to the concerns of both industry and the ever-expanding user audiences. 2501 M Street, NW, Washington, DC 20037 202-887-1100 Telex 89617 (CMA WSH) Health and Safety Contacts November 30, 1989 Page 2 During development of the guideline, we have received input from many new and long time users and developers of MSDSs. The guideline is the work product of over 40 individuals representing 30 CHA member companies. Input has also-been provided by other individuals and organizations within the chemical industry, other industries, outside users and regulatory bodies. MSDSs have recently become the subject of congressional hearings, a General Accounting Office (GAO) investigation, and international discussions. A second GAO investigation and an OSHA notice requesting comment on ways to improve the MSDS are pending. Our plans include continued CMA involvement in these arenas and pursuit of international harmonization of MSDS requirements. We recognize that your company has considerable experience with MSDSs. Your comments and suggestions on the first distribution of our work product will be greatly appreciated. Please return your comments, in writing, no later than January, 10, 1989 to Kathryn A. Roslca, Associate Director, Health Issues at the CMA address. Please call her at 202/887-1282 if you have any questions. Sincerely yours Enclosure cc: (w/enclosure) G. D. Strickland Geraldine V. Cox, Ph.D. Vice President-Technical Director VVV 000010847 CHEMICAL MANUFACTURERS ASSOCIATION DRAFT Guidelines for the Preparation of Material Safety Data Sheets 11/30/89 WV 000010848 Draft 11/30/89 LEGAL NOTICE This guideline is intended to be an information document to assist individuals responsible for the development and review of Material Safety Data Sheets (MSDSs) used and handled in the United States. It is not within the scope of this guideline to analyze specific legal, policy, or technical issues that may arise in the compliance with the OSHA Hazard Communication Standard. Each company should consult with OSHA or its own legal counsel as to compliance issues. CMA does not make any warranty or representation, either express or implied, with respect to the accuracy, completeness, or utility of the information contained in this guideline; nor does CMA assume any liability of any kind whatsoever resulting from the use of or reliance upon any information, procedure, conclusion, or opinion contained in this guideline. Copyright 1989, Chemical Manufacturers Association 0000108*9 VVV Draft 11/30/89 CHEMICAL MANUFACTURERS ASSOCIATION DRAFT Guidelines for the Preparation of Material Safety Data Sheets Table of Contents Chapter Title Page Forward [to be added] ...................................................................... Credits [to be added]......................................................................... 1 Introduction ....................................................................................................... 1 2 Scope .............................................................................. 3 About the Guideline ........................................................................... 2 A. Organization of the Guideline ................................................ 2 6. Audiences for MSDSs ......................................................................... 3 C. Classification Terns ........................................................................... 3 4 Preparing an MSDS .......................................................................................... 4 A. MSDS Organization....................................................... B. Appearance/Cossunication Principles ................................... C. General Contents ..................................................................................... 6 9 4 1. Supplier Inforaatlon ...................................................................... 9 2. Emergency Numbers .............................................................................. 9 3. Review/Preparation Date............................................................. 10 4. Units of Measurement ..................................................................... 10 5. Page and Section Numbers.......................................................... 10 6. Revision Indicators ....................................................................... 11 7. Key/Legend ........................................................................ 8. MSDS Number............................................... *................................ 12 9. Disclaiaer .............................................................................................. 12 H D. Hazard Deterainatlon................................................. 12 1. Collecting the Information..........................*...................... 12 2. Determining Hazards ....................... *....................... 13 5 Sections of An MSDS ................................................................................... 14 A. Section 1: Material Identification ..................................... 14 Material Identity............ .......................................... Emergency Overview ........................................................................ 15 VVV Q00010B50 14 Draft 11/30/89 Chapter Title page 5 (cont.) 8. Section 2: Chemical or Hazardous Components .............. 18 C. Section 3: Potential Health Effects ....................... 19 D. Section 4: First Aid ..................................................................... 25 First Aid ................................................................................................ 25 Note to Physicians ......................................................................... 26 E. Section 5: Fire and Explosion ............................................... 28 F. Section 6: Reactivity .................................................................. 31 G. Section 7: Spill and Leak Response .................................. 32 H. Section 8; Personal Protection/Exposure Controls ............................................... 33 Personal Protective Equipment ................................................ Engineering Controls ..................................... Exposure Guidelines ......................................................................... 33 37 36 I. Section 9: Storage and Handling......................................... 40 Storage .......................................... 40 Handling ..................................................................................................... 40 J. Section 10: Physical and Chemical Properties .... 42 K. Optional Section: Toxicological Information ..... 43 L. Optional Section: Ecological Information .................. 44 Ecotoxicological Information ............................................... Chemical Fate/Information............................................... 44 44 M. Optional Section: Regulatory Information .................. 45 Transportation ...................................................................................... U.S. Federal Regulations ............................................................. International Regulations.......................................................... State Regulations .............................................................................. 45 46 47 48 N. Optional Section: Supplemental Information ............. 46 Waste Management Information (Including Disposal). Label Text ................................................................................................ Hazard Rating Systaas .................................................................... 48 30 30 6 Evaluating the Completed MSDS........................................................ 51 VVV 000010851 Draft 11/30/89 Title Page References ................................................................................................................ 52 Forms and Examples [to be added]................................................................ 53 Glossary ............................................................................................................................... 54 Appendices ......................................................................................................................... 1. Health Hazard Evaluation from American National Standard for Precautionary Labeling - Hazardous Industrial Chemicals; ANSI Z129.1-1986 ........................................... 2. Appendix B of the OSHA Hazard Communication Standard .... 3. State Agency Right to Know Contacts ................................................... 1*1 2*1 3*1 Index [to be added] 00oIoa5^ Draft 11/30/89 nBAPTKB 1: utoodoctioh This guideline is intended for use by individuals responsible for developing and reviewing Material Safety Data Sheets (MSDSs) on materials and hazardous chemicals used and handled primarily in the United States, and subject to the Federal OSHA Hazard Communication Standard (HCS). The guideline may also be helpful to identify additional MSDS requirements for materials used and handled in certain states, as well as outside of the United States. In the past, the MSDS was written for health and safety professionals and for trained workers employed by chemical companies and their customers. Expansion of federal and state right-to-know regulations has broadened this audience to include fire departments, emergency responders, state and local emergency planning groups and members of the community. Because of the information needs and diverse background of this expanded audience, the information in a MSDS must be presented in a more consistent and understandable form. Wherever possible, MSDS information should also be presented in language the layman can understand. A Material Safety Data Sheet describes the hazards of a material and provides information on how the material can be safely handled, used, and stored. It is a summary of material safety information. For completeness and clarity, it should contain sections on material identification, chemical or hazardous components, potential health effects, first aid, fire and explosion, reactivity, spill and leak response, personal protection/exposure controls, storage and handling, and physical and chemical properties. It may also include toxicological, ecological, regulatory, and other useful information. MSDSs cannot include information on each and every unique application of the material, although they should consider the hazardous exposures resulting from customary and reasonably foreseeable occupational use, misuse, handling and storage. The MSDS is only one source of information on a material; as such, it is best used along with technical bulletins, labels, training, and other communications. The OSHA Hazard Communication Standard (HCS) requires an MSDS be prepared for chemicals that are hazardous according to the criteria described in the Standard. This guideline recommends MSDSs be prepared for all chemical materials to ensure clear communication on the material and it's hazardous nature. This guideline uses the term "material1* to denote this wider scope of coverage. The term includes all types of classifications of chemicals such as products, raw materials, isolated manufacturing intermediates, as well as hazardous and non-hazardous chemicals. Also covered under "materials" are articles that may normally be considered non-hazardous, but may give off hazardous chemicals during customary and reasonably forseeable use and misuse, handling and storage. 000010S53 -1- Draft 11/30/89 CHAPTER 2: SCOPE This guideline applies to the preparation of MSDSs for hazardous chemicals and materials used under industrial occupational conditions. It presents basic information on how to develop and write an MSDS. It identifies information that must be included to comply with the U.S. 05HA Hazard Coomiunication Standard. It also identifies information that should be included for completeness, clarity, and format consistency. Optional information is also presented for compliance with other federal, state, and international health, environmental, and safety laws or regulations. CHAPTER 3; ABQOT TOE GOTPgT.TMR This guideline is organized to present concepts and guidance to an HSDS preparer. The whole guideline should be read and understood because many MSDS sections are interrelated. A complete, logical and internally consistent MSDS is more likely to result from the orderly approach presented in this guideline. This guideline is designed as an aid to the MSDS preparer and should be used along with the professional judgement and common sense of the experts who provide all the information included on the MSDS. This guideline cannot be considered to be a resource for providing all information necessary for full compliance with rules, regulations or laws. Each company and MSDS preparer must diligently remain aware of all legal requirements relating to MSDSs, both current and evolving future ones. A. ORGANIZATION OF THE GPmKT.TNR The rest of this document presents information in the order that an MSDS preparer is likely to need it. Chapter 4 discusses the steps used to prepare an MSDS including: o formatting issues such as recommended section headings and order of appearance o principles for the effective communication of information in MSDSs o general information and principles common to all MSDSs (e.g., supplier information, page numbering, use of units of measurement) o collecting information and determining hazards Chapter 5 discusses individual sections of an MSDS, including purpose, content and audiences. Where appropriate, brief examples are given. Chapter 6 contains a brief discussion on evaluating the completed MSDS. Wv 000010854 -2- Draft 11/30/89 Chapter 7 presents examples of MSDS layouts and/or specific sections of MSDSs to illustrate some concepts described by this guideline, [chapter to be added] The glossary defines terms used in this guideline as well as some terms commonly used in MSDSs. The glossary also offers some suggestions for alternative wording for technical terms. B. AUDIENCES FOR MSDSs In each discussion of an MSDS section, the likely audiences for the information are identified. This is done to help you decide on the technical language level to use with each section and supports one of the basic purposes of this guideline. Under the OSHA HCS, manufacturers provide MSDSs to their customers and these employers make MSDSs available to their employees. Other statutes and practices make MSDSs available to a wider audience. The audiences are identified throughout the guideline as: o Community Member o Emergency Responder o Employee o Employer o Environmental Professional o Medical Professional o Occupational Health & Safety Professional As a general rule, the language used in an MSDS should be understandable to the widest audience possible. At the same time, recognize that technical data must often be presented in technical language in order to be useful to some intended audiences. C. CTA8STTTCATI0H TERMS This guideline uses the terms MANDATORY. RECOMMENDED. and OPTIONAL when discussing both specific elements and general items to include in an MSDS. These classifications appear throughout the guideline and reflects the need to include information according to the following criteria: MANDATORY(M): RECOMMENDED(R): OPTIONAL(O): Required by the U.S. OSHA Hazard Communication Standard (29 CFR 1910.1200) Should be included for completeness, content and format consistency, clarity, and readability of MSDSs, unless inappropriate May be useful information for some materials 3 VVV 000010855 Draft 11/30/89 CHAPTKB 4; PREPAPTMR AM M<m<8 This chapter of the guideline provides information to an MSDS preparer that will help structure and organize an MSDS. Collecting information and conducting a hazard determination for a material is also discussed, along with presenting the information to readers of an MSDS. A. MSDS ORGANIZATION This guideline considers two main uses of the MSDS to be: o a training tool for workers o a resource for emergency responders The effectiveness of MSDSs for these purposes will be Improved by making the information available in the same order so it is easier for the reader to find, regardless of the supplier of the MSDS. Therefore, this guideline recommends titles and a specific order for the sections of an MSDS. The guideline also recognizes that for some materials, it will be appropriate to Include additional information in optional sections for other audiences. The logical sequence of questions which the MSDS should answer and leads to the recommended order, is listed below. Where appropriate, key information for emergency responders should be located near the beginning of the MSDS because it often is needed quickly. In cases where the information provided answers a question pertaining to both the health and safety of people and the environment, information pertaining to people should be placed first. WHAT IS THE MATERIAL AND VHAT DO I NEED TO KNOW IMMEDIATELY FOR AN EMERGENCY? Material Identification o links the MSDS to the material and to lists of hazardous materials o may also provide an emergency overview ffiinmlrnl or Hazardous Components o lists the OSHA hazardous components o may also list non*hazardous components o may also include exposure guidelines of components WHAT ARE THE POTENTIAL HAZARDS AND VHAT SHOULD I DO IF A HAZARDOUS SITUATION OCCURS? Potential Health Effects o provides information on the possible adverse health effects that might result from reasonably foreseeable use and misuse wv 000010856 -4- Draft 11/30/89 First Aid o provides instructions if an exposure requires immediate treatment o may also include instructions to medical professionals Fire and Explosion o describes the fire and explosive properties of the material o provides basic fire-fighting guidance Reactivity o identifies conditions which may result in a hazardous situation or reaction Spill and Leak Response o provides instructions for responding to spills, leaks, or releases of the material HOW CAN HAZARDOUS SITUATIONS BE PREVENTED? Personal Protection/Exposure Controls o provides guidance on personal protective equipment o provides information on engineering controls o may also include exposure guidelines Storage A Handling o provides information on appropriate storage and safe handling practices IS THKMK ADDITIONAL TECHNICAL OR SUPPORTING INFORMATION? Physical and Chemical Properties o provides additional data that can be used to help characterize the material and design safe work practices Toxicological Information o can be used to provide toxicological information on the material and/or its components Ecological Information o can be used to provide information on the environmental effects of the material VVV 0000X0857 5 Draft 11/30/89 Regulatory Infnrmntion o can be used to include regulatory information the supplier would like to tell about the material Supplemental Information o can be used to provide other information (including waste management/disposal) All sections from Material Identification through Physical and Chemical Properties should appear, in the above order, on all MSDSs. Other sections may not always apply. This guideline recommends that certain types of information be placed within certain sections. Because information has more than one purpose, some flexibility in placement is recognized. For example, exposure guidelines may be placed in the Chemical Components section along with the names of components; or they may appear under Personal Protection/Exposure Controls. Likewise, components listed strictly for state right-to-know purposes may be placed In a Chemical Components section or under the optional Regulatory section. B. APPEARAHCK/OMfONICATION PRINCIPLES Preparing a material safety data sheet involves collecting facts from a wide variety of subject areas and summarizing them. The result must be understandable and useful to a diverse audience, without oversimplifying the information so much that it is no longer useful to e trained specialist. The MSDS should be designed for use in the workplace and in an emergency where the user is under stress, under time constraints and may have poor visibility. Vriters must recognize that the MSDS may be read for the first time in an emergency end could be the only imediate source of information on the material. Some of the following suggestions may be useful for MSDS preparers: Appearance: For uniformity and filing, as wall as for further electronic distributions, a vertical (portrait) format is recommended: The layout should be simple, with well marked and identified sections. The text should be horizontal so the text flows from left to right, as is natural for English readers. vvv 000010858 6 11/30/89 2 Avoid right justification of text since this Bakes it more difficult to control eye movement and to read, especially for an impaired or poor reader. Avoid frequent variation of line spacing, especially when trying to crowd more text onto a page or into a section. Use space to separate fields and sections so reading is simplified. Use simple type styles. Ornate styles are sore difficult to read. Also avoid using a variety of type styles on the same MSDS. Long strings of text typed in all capital letters are more difficult to read. Arabic numbers (e.g., 1, 2, 3) are aore familiar than Roman numerals (e.g., I. II, III) to the average reader. Generally 10-14 point type size is easily readable for an MSDS. Type sizes of 12 or 14 points are usually considered easily readable. A 10 point type size is the minimum that is easily readable. EXAMPI: 1Mb is S ptosi type This is 12 paint type Printed type should be clearly legible. Do not depend solely on color to highlight heading or text. Some users may be color blind. The use of reversal effects (e.g., white letters on dark background) for large blocks of text can decrease readability. Avoid pictograms and symbols, especially without training programs. If you do choose to use them, use only extremely common ones to avoid ambiguity and unfamiliarity. Avoid using footnotes on the MSDS. Many readers are unfamiliar with them. Instead, put information in parentheses within the sentence. Right justification is when the margins on the right hand side are even, or lined up; usually done by using uneven spacing. VVV 000010859 -7- Draft 11/30/89 Remember -that the USDS may be electronically reproduced and/or transmitted (e.g., faxed, copied or scanned). Small or ornate print, color, and symbols may not be readable on a receiving end. Reading Level and Comprehension: One of the greatest challenges in preparing a material safety data sheet is writing so that various audiences can read and understand the information. Reading levels of users vary widely. The target audiences range from an untrained person needing general information to a highly trained professional. The information being conveyed is often very technical and must be complete enough for the specialist and yet be understandable for the less trained MSDS user. An additional challenge is that the target audiences change from section to section. Therefore, the reading level should change as well to adapt to the target audiences. Word choice and sentence structure greatly affect reading level and comprehension. The following rules of thumb may be helpful to improve the readability and comprehensibility of the MSDS. Keep sentences short and direct. Use no more than two subordinate clauses. Use the active voice as much as possible. EXAMPI: Acid causes skin bums, (active) Bums to the skin are caused by acid, (passive) Sentences that include a long string of effects or other items can be made clearer by putting them into a list. EXAHPUE: Inhalation of this material can cause: - Eye, nose end throat irritation - Shortness of breath - Coughing - Sneezing Use short words of one or two syllables as much as possible. Choose commonly used, familiar words, but avoid colloquialisms and slang. vvv OOOOlGri60 8 Draft 11/30/89 Use only common abbreviations and acronyms, and then give their definition as soon after their first use as possible. Occasionally however, an abbreviation or acronym may be so familiar to intended audiences that it may be used without a definition. In fact, some may be more familiar than the full name (e.g., OSHA, EPA, SARA, F and C. Avoid unnecessary technical language and jargon except for information essential to appropriately trained individuals. When technical language is necessary in sections targeted for non-technical audiences, it is advisable to also include a less technical explanation. Refer to the glossary for examples of some useful alternatives for technical words. Responses to MSDSs from workers and customers, can be very useful in determining comprehension and the readability of MSDSs. The use of a consistent statement or phrase is beginning to gain popularity, especially where translation becomes a consideration. C. GENERAL CONTENTS There are nine general items common to MSDSs. Most of these items are either mandatory according to the HCS or recommended to help the reader use the MSDS. The following information will be helpful when designing the overall layout of an MSDS. 1. SUPPLIER INFORMATION (HANDATORT) Company name and mailing address must be listed on the MSDS. A telephone number where information can be obtained is mandatory. This identification should stand out so the reader can find it quickly. It's usually part of the material Identification section, in the logo or letterhead, or near the top or bottom of the first or last page. 2. EMERGENCY NUMBERS (KECOtffENDED) A company may have a specific telephone number for quick response to emergencies. This number should be readily identifiable on the MSDS. Indicate if the telephone number has any restrictions, such as hours of operation (e.g., M-F 8:00 a.m. - 6:00 p.m. EDT or 24 hours) or limited to a certain type of emergency (e.g., medical, transportation). Some companies use CHEMTREC's 24 hour toll-free telephone number to help respond to their chemical transportation emergencies. To become a part of this system, contact the Chemical Manufacturers Association ( 2501 M Street, NW, Washington, DC 20037). ooooi0861 ^\fV 9 Draft 11/30/89 3. REVIEtf/PREPARATION DATE (MANDATORY) Every MSDS oust have a preparation or revision date. The date may be displayed in different formats; it is often printed on every page of the MSDS. This helps the reader know that the entire MSDS is the same version. t If any other dates are used, they should be clearly labeled to avoid possible confusion. 4. UNITS OF MEASUREMENT (MANDATORY) Numerical data must be presented with the appropriate units of measurement. The units of measurement should be those most appropriate for the United States. The MSDS can also include alternate units for other countries, (e.g., the inclusion of values expressed in metric units would be appropriate for materials shipped to Europe and Canada). Indicate the temperature scale of items such as flash point and boiling point by inserting F or C (Fahrenheit or Centigrade). Pressure and other properties should also be shown in appropriate units. For example, pounds per square inch (PSIG) could be used for higher pressures and millimeters of mercury (mmHg) might be appropriate for below atmospheric pressure. For properties that vary with temperature or other conditions (e.g., vapor pressure, viscosity, solubility), indicate the conditions under which the value was measured or calculated. EXAMPLES: Boiling Point = 200F at 10 mmHg Vapor Pressure =4.1 PSIG at 70F. Some properties are dimensionless. Density has units of weight per volume, while specific gravity is s dimensionless number. However, the standard against which specific gravity is measured (most commonly water or air) should be indicated. Properties such as pH are truly dimensionless, and readers of a data sheet who seek out pH values will know this. 5. PAGE AND SECTION NUMBERS (REGOWENDED) Page numbers make it obvious to the reader that the pages are in the proper order and none are missing. Section numbers allow for easy referencing. Numbering makes it possible to know when all pages and sections are in hand when telefaxing or copying an MSDS. 10- VV* OOOQIO062 Draft 11/30/89 EXAMPIES: Page 1 or page 1 of 6 Continued on next page. This is. the end of Section 2. This is the last page of this MSDS. Number the recommended section headings (Material Identification through Physical and Chemical Properties) using Arabic numerals (e.g., 1, 2, 3) rather than Roman numerals (e.g., I, II, III) or letters of the alphabet. 6. REVISION INDICATORS (RECOMMENDED) Readers need some type of revision indicator to help them determine what has been changed in an updated MSDS. Below are some methods used to indicate revisions in either a cover letter or in the Supplemental section of the MSDS. EXAMPLES: o This MSDS has been revised in the following section(s): 1. Material Identification 5. Physical and Chemical Properties o A symbol in the right hand margin of this MSDS indicates that this line has been revised. o The personal protection section of this MSDS was revised due to new recommendations. o The pH was added to Section 5. 7. KET/IEGEND (RECOMMENDED) In general, try to avoid abbreviations since they are often confusing or unknown. If used, include a key/legend to define abbreviations or potentially ambiguous terms. For example, N/A has been used to denote ''not available" and "not applicable." Without an explanation, the meaning is unclear. -11- WV 000010863 Draft 11/30/89 8. USDS NUMBER (OPTIONAL) Suppliers often will assign a number to an MSDS to help track or identify it. If a MSDS number is used, it will usually appear on every page to make sure that all the pages are for the same product. 9. DISCLAIMER (OPTIONAL) The disclaimer is usually intended to provide limits on the liability of the MSDS preparer when the specific material is used, misused, handled or stored in a way that is not customary and reasonably foreseeable. The use of a disclaimer and its language is usually decided by a preparer's legal counsel and is typically found at the end of an MSDS. D. HAZARD DETERMINATION 1. COLLECTING IRE INFORMATION The HCS requires that the MSDS present the known hazards of the material. As a first step, a preparer needs to collect information about the material and/or its components. Types of information needed include: o component information including all ingredients and known impurities, with Chemical Abstract Service (CAS) registry numbers and concentrations o physical and chemical characteristics o uses and reasonably foreseeable misuses of the material o toxicity information obtained from: internal company testing MSDSa or letters from suppliers published information trade association testing or communication o Appendix C of the Hazard Communication Standard which provides a recommended base listing of outside sources for toxicity information Maintain a bibliography of references used in your evaluation. This information will provide needed internal documentation. It will also help an MSDS preparer (and others) update the MSDS, answer inquiries, and have a historical reference. VVV 000010864 -12- Draft 11/30/89 2. DETERMINING HAZARDS The collected data must then be assessed to determine the potential physical and health hazards associated with the material. This assessment of the data is the hazard determination and forms the basis for what is written on the MSDS. In assessing physical hazards of the material, primary sources of information are actual test data for the material or calculations from data on components. The HCS defines criteria for physical hazards, which are often numeric (e.g., flammable). Professional judgement plays an important role in determining physical hazards. Health hazards are also defined by the HCS. These hazards are generally based on animal testing or human health effects as described in Appendix A of the Standard. With health hazards, evaluations tend to rely more on interpretation and professional judgement on relevance of the data than in the case of physical hazards. The mandatory OSHA Health Hazard Determination description is found in Appendix B of the Standard (Appendix 2 of this guideline). Some helpful concepts to remember in evaluating health hazards are: o One scientifically valid study with statistically significant results is sufficient evidence to note the effect on the MSDS o Chemicals are considered "hazardous" if they: - are regulated by OSHA (29 CFR 1910, Subpart Z) - have established TLVs listed by ACGIH - are listed by NTP, IARC, (see glossary) or OSHA as carcinogens or potential carcinogens - meet the criteria of Appendix B of the HCS o Evaluation of untested mixtures requires that the mixture be assumed to present the same health hazards as do the components above the OSHA trigger (see discussion in Potential Health Effects. Chapter 5) o If the preparer has evidence to indicate that an OSHA or ACGIH exposure threshold for a component (present below OSHA concentration trigger) may be exceeded, then the mixture shall be assumed to present the hazards of that component (see discussion in Potential Health Effects. Chapter 5) Threshold Limit Values for Chemical Substances and Physical Agents in the Work Environment. Am****^*" Conference of Governmental Industrial Hvsienlsts. latest edition WV 000010B65 13 Draft 11/30/89 The American National Standard for Hazardous Industrial Chemicals Percautionary Labeling, Z129.1-1988 also provides a discussion of the health hazard evaluation (Appendix 1). When the physical and health hazards have been identified their impact on all relevant sections of the USDS must be evaluated. The primary sections in which to present the details of the hazards are Potential Health Effects for health effects and Physical and Chemical Properties. Fire and Explosion and Reactivity for physical effects. Each of the other sections in the MSDS builds on or supports the hazards identified in this step. Now you are ready to draft the USDS text. The rest of this guideline will help you decide what information to include. It will also help you determine where the information should be located and the appropriate language levels to use. CHAPTER S: SECTIONS OF AM MSDS A. Section 1: MATERTAT. TngHTTETCATTfiN Material Identity PURPOSE: This subsection names the material and links the MSDS to the label, internal lists of hazardous materials and shipping documents. This information is essential for all users of the MSDS. SCOPE: The identity of the material must be directly linked to the name found on the material label (MANDATORY), internal lists of hazardous materials (MANDATORY) and/or shipping papers (RECOMMENDED). This name should appear prominently at the top of each page (RECOMMENDED). The material may also be identified by alternate names or synonyms (OPTIONAL). A company product code may also be added for easy Identification (OPTIONAL). If one generic MSDS is used to cover several grades or minor variants of a materiel, all grade or material names must be listed on the MSDS (i.e. as synonyms) or the MSDS must clearly delineate the range of materials Included (MANDATORY). EXAMPIX: o the material name on the label is Methoquin AB; the MSDS siust contain both the generic name (Methyl substituted quinolites) and the specific name Methoquin AB vvv 0000108^6 -14 Draft 11/30/89 o MSDS uses Polypropylene 5000 series (5000-5999) as the material name and the label states the specific name Polypropylene 5005 Emergency Overview PURPOSE: This overview describes the material's appearance and most significant immediate concerns for emergency response personnel. SCOPE: State the appearance which includes the physical state of the material (RECOMMENDED). Include immediate health, physical, and environmental hazards associated with emergency response situations (RECOMMENDED). Labeling statements of hazard will often be suitable to describe the hazards listed in this section (OPTIONAL). Pointers to where key information can be found in the MSDS may be used (OPTIONAL). This overview should be made a part of the Material Identification section. It can appear as a paragraph or as a series of ANSI-style label statements. Items considered for the emergency overview include: What does the material look like? (color, physical form, shape) Does it have a distinctive odor? (sweet, acrid, sour) The emergency overview should also address severe immediate hazards that may be encountered in an emergency situation. Following are some questions which may assist you in determining severe immediate hazards: Is the material flammable, combustible or explosive? (DOT definitions) Does it present any significant or unusual fire or explosion hazard? (e.g., travel to source of ignition, forms explosive mixtures) Is the material an oxidizer, organic peroxide or pyrophoric? (OSHA/DOT definitions) Is the material shipped under pressure? (e.g., compressed gas, liquified gas - DOT) VVV 000010867 15 Draft 11/30/89 Are there significant reactivity hazards associated with emergency conditions? (e.g., uncontrolled reaction with water or organics; will spontaneously decompose) Is the material highly toxic (OSHA) or poisonous (DOT)? If so, by what route of entry? Is the material severely hazardous when inhaled? (e.g., strong narcotic action, corrosive, displaces air causing an asphyxiation hazard, respiratory sensitizer, severe irritant) Does it cause burns to living tissue? (e.g., corrosive to skin, eyes, respiratory tract) Does it cause severe skin or eye irritation? Does it require specialized medical treatment for any contact or exposure? Is it a confirmed or probable human carcinogen? (NTP listed, IARC Class 1 or 2A, or OSHA listed carcinogen) Can a single exposure result in other serious adverse health effects? (e.g., confirmed or probable human teratogen) Is it highly toxic to aquatic organisms? (e.g., kills fish or algae at low concentrations) Will it be persistent in the environment? (e.g., PCB's, mercury) Generally, if a hazard is not included on the label, it would not be included in the Emergency Overview. If the material is not hazardous, you may want to include a statement indicating that it presents little or no hazard (if spilled) and/or no unusual hazard if involved in a fire (RECOMMENDED). / EXAMPLE 1: (Paragraph style with Pointers) Mineral Acid A colorless liquid which can react violently with water producing white clouds of toxic and corrosive vapor. Extremely corrosive to all body parts and may be fatal with contact, If swallowed or if inhaled. Exposures require VVtf 000010868 16 Draft 11/30/89 specialized first aid and medical follow-up. Can react violently with water producing clouds of toxic and corrosive vapor. Not flammable, but reacts with most metals to form flammable hydrogen gas. See Sections 3, 4, 5, 6, 7, 8 EXAMPLE 2: (Label Style Without Pointers) Inorganic Salt White to grey solid. Causes irritation to skin and eyes. Not flammable. EXAMPLE 3: (Label Style With Pointers) Plastic Beads Cylindrical beads in various colors. Can burn in fire, releasing toxic vapors. See First Aid and Fire and Explosion for details. EXAMPLE 4: a. (Paragraph Style Without Pointers) Polymer Solution A milky white liquid with a strong "sweet" odor. Can cause severe eye irritation and will burn if involved in a fire. Solutions are extremely slippery when spilled. Highly toxic to fish and other water organisms. b. (label Style With Pointers) Sane Material Milky white liquid with a strong "sweet" odor. Causes eye irritation. Will burn if ignited. Extremely slippery. Highly toxic to fish and other water organisms. Health Hazards - Section 3 First Aid - Section 4 Fire & Explosion - Section 5 Spill and Leak Response - Section 6 yyy 000010869 17 Draft 11/30/89 KUMPU 5: (Paragraph Style With Pointers) Building Material That Contains Asbestos A brown to green flat sheet that poses little or no immediate hazard. Repeated exposures to dusts via inhalation (breathing) can result in serious delayed effects. Does not burn, but may melt in a fire, releasing hazardous fibers. Health Effects - Section 4 z B. Section 2: CHEMICAL OR ITAZARDOPS COMPONENTS PURPOSE: This section must identify at least the components of a material that contribute to its hazard according to the HCS (MANDATORY). State or local regulations may require further disclosure. Some manufacturers may choose to identify all significant components of a material, and use the heading "Chemical Components." Other manufacturers may choose to identify only the chemicals that contribute to specific hazards, and use the heading "Hazardous Components'*. This information is useful to all MSDS users. SCOPE: Chemical Components option: o List chemical name of all significant components (RECOMMENDED). Be sure to include hazardous components as defined by OSHA (MANDATORY). If one or more of the components is a trade secret, a company may so indicate in lieu of identifying the component. However, if the component is defined as hazardous by OSHA, that fact should also be included. o Provide percentages or ranges of percentages by weight or by volume (state which), unless percentages are trade secret (RECOMMENDED). o List corresponding CAS registry number, where appropriate, for each component (RECOMMENDED). o List OSHA PELs4 , ACGIH TLVs, or established company exposure guidelines for components of a mixture (MANDATORY information, OPTIONAL placement; see Personal Protection/ Exposure Controls for discussion) 4 OSHA Permissable Exposure Limits; see Glossary -18 VVV Q0001QB70 Draft 11/30/89 Haaardqus Components option: o List chemical and common name of hazardous components as defined by OSHA (MANDATORY). If one or more of the hazardous components is a trade secret, a company may so indicate in lieu of identifying the component. o List chemical name of components for compliance with state or local right-to-know regulations (OPTIONAL). o Provide percentages or ranges of percentages by weight or volume (state which) for those hazardous components, unless percentages are trade secrets. (RECOMMENDED) o List corresponding CAS registry numbers, where appropriate, for each component. (RECOMMENDED) o List OSHA PELs, AC6IH TLVs, or established company exposure guidelines for components of a mixture (MANDATORY information, OPTIONAL placement; see Personal Protection/Exposure Controls for discussion) C. Section : PdlENTTAT, HltAT.TH KVyTO PURPOSE: This section provides information on the potential adverse health effects and symptoms associated with exposure to the material, and its components or known byproducts, under reasonably foreseeable use, misuse, handling and storage conditions (MANDATORY). It also contains information required by certain regulations, related to human health hazard (e.g., positive carcinogenic potential determined by IARC, OSHA, NTP). The information should be presented in lay language since it is the primary source of health effect information for all audiences ranging from the community and employee to the health and medical professional. It will aid in determining handling and other procedures for the material. Supporting data, such as toxicology epidemiology studies should be included in the separate Toxicological Information section of the MSDS (RECOMMENDED). If the preparer decides to place supporting data in this section, it should be placed at the end of the section so it won't distract the audience from understanding the potential health hazards of the product (RECOMMENDED). VVv 00I0S71 -19- Draft 11/30/89 SCOPE: This section includes information related to human health effects, if known or presumed likely. This section presents only relevant health effects and presents them in a way that can be quickly and easily understood. The OSHA definition of health hazard is a chemical for which there is statistically significant evidence based on at least one scientifically valid study which demonstrates that acute or chronic health effects may occur in exposed individuals. (See Chapter 4 of this guideline for discussion of the hazard determination process.) Chemicals that must be addressed include: o OSHA regulated (29 CFR 1910.1000 Subpart Z) or ACGIH listed; o Carcinogens or potential carcinogens listed by IARC, NTP or OSHA; o All chemicals meeting criteria of Appendix B of the HCS. The OSHA standard also establishes methods for evaluating the health hazards of untested mixtures. The basic rule is that if there is no appropriate testing on the mixture, you must address the health effects of each chemical in the mixture present at concentrations of 1% or greater (trigger is 0.1% for carcinogens or potential carcinogens) (MANDATORY). If a hazardous material is present in a mixture below the 1% concentration trigger (0.1% for carcinogens) and/but could be released in concentrations exceeding OSHA or ACGIH exposure guidelines, or present a hazard in those low concentrations, the mixture shall be assumed to present the same hazard as the components (29 CFR 1910.1200). The mixture testing must address each of the data elements for which there are positive test results for the chemical components (MANDATORY). For example, if a component has been shown to cause reproductive effects on test animals, this information must be presented in the MSDS for the mixture unless the mixture has been tested in test animals and been shown not to cause reproductive effects. The MSDS must include the following elements if available or known (MANDATORY): o Relevant route(s) of exposure (e.g., eye, skin, inhalation and ingestion) o Lengths of exposure (e.g., single, repeated, lifetime) VVY 000010872 20 Draft 11/30/89 o Severity of the effect (e.g., mild, moderate, severe) o Target organ(s) (e.g., liver, kidney, lung) o Type of effect (e.g., irritation, allergic skin response, rashes, birth defects, congestion, cancer, blood effects) o Signs and symptons of exposure o Medical conditions generally known to be aggravated by exposure to the material (see also Note to Physicians) Identify the source of the hazard, (e.g., that the noted effect is due to a specific component within the mixture) (RECOMMENDED). You must identify the carcinogens or potential carcinogens listed by OSHA, IARC, or NTP (MANDATORY). Include them in this section during the discussion of health hazards, or identify the hazard in this section and note the listing of the chemical in a separate section, such as the Hazardous Components. Regulatory, or Supplemental Information. For data on effects in animals, the MSDS must list the anticipated health effects in this section if they are considered relevant to human health (MANDATORY). It may be appropriate to qualify the effect with the phrase, "based on animal testing this product is presumed to ..." This would permit the reader to understand that there are no human case histories or epidemiological studies to rely on. This section should not include information on toxic effects which the author does not believe are relevant to humans. If appropriate, the potential effects should be mentioned here with a reference to the Toxicological Information section where appropriate discussion of the study, can be made. This type of data presentation can be used to improve the readability of the document across audiences. EXAMPU 1: Potential health effects separate from toxicological data -21- VVV Q0G010873 Draft 11/30/89 Section 3; Potential Health Effects EYE o Hay cause slight eye irritation. SKIN o Prolonged exposure may cause skin irritation. o A single prolonged exposure is not likely to result in the material being absorbed through skin in harmful amounts. INGESTION o Single dose oral toxicity is low. o Small amounts swallowed incidental to normal handling operations are not likely to cause injury; swallowing amounts larger than that may cause injury. o If aspirated (liquid enters the lung), may be rapidly absorbed through the lungs and result in injury to other body systems. INHALATION EFFECTS o Excessive vapor concentrations are attainable and could be hazardous on single exposure. o Signs and symptoms of excessive exposure may be central nervous system effects such as sleepiness and unconsciousness. o May cause irregular heartbeats, especially under conditions of stress. SUBCHRONIC EFFECTS (TARGET ORGAN) o Repeated excessive exposures may cause liver and kidney effects. CHRONIC EFFECTS/CARCINOGENICITY o Has been shown to cause cancer in laboratory animals. o Is listed as a potential carcinogen by IARC. [separate section which is located in the later part of the MSDS] Optional Section; Toxi**1g*gal Information ACUTE ORAL EFFECTS Single dose oral toxicity is low; the LD50 in rats given the material as a 10% corn oil solution was 1870 mg/kg for males and 3730 mg/kg for females. Liver necrosis was observed in survivors. SKIN EFFECTS The material was only slightly irritating to rabbit skin. The P.I. Score is 0.8 out of 6.0. The potential for absorption through the skin in acutely toxic amounts is low; the dermal U)50 in rabbits Is 20,000 mg/kg. -22- VMM ^0001087^. Draft 11/30/89 EYE EFFECTS The material was slightly irritating to the rabbit eye. P.I. Score is 18 out of 110. The ACUTE INHALATION The 4-hr LC50 in rats was 2500 mg/kg (357 ppm). CNS depression would be expected. May be a cardiac sensitizer based on structural analogy. SUBCHRONIC EFFECTS Repeated inhalation exposure of rats for four or seven hours per day for eight days at 1000 ppm resulted in ataxia, decreased body weight, increased S6PT, and caused increased relative liver and kidney weights with accompanying histologic changes of an adaptive nature. A two-week oral gavage study in rats given 300 mg/kg/day showed hepatic hypertrophy in females but not in males. CHRONIC EFFECTS/CARCINOGENICITY A bioassay was conducted by gavage in rats given 60 or 150 ng/kg/day and mice at 230 or 550 mg/kg/day. Both rats and mice showed evidence of increases in hepatocellular carcinoma and adenoma. The doses did not exceed the MTD and the material is listed as a potential carcinogen by IARC. MUTAGENICITY The material was negative in the Ames test. It bound covalently in vivo to DNA, RNA and tissue proteins from rats and mice when injected i.p. EXAMPI 2: Potential health effects incorporating toxicological data in this section Section 3: Potential Health Effects EYE o May cause slight eye irritation. SKIN o Prolonged exposure may cause skin irritation. o A single prolonged exposure is not likely to result in the material being absorbed through skin in harmful amounts. INGESTION o Single dose oral toxicity is low. o Small amounts swallowed incidental to normal handling operations are not likely to cause injury; swallowing amounts larger than that may cause injury. o If aspirated (liquid enters the lung), may be rapidly absorbed through the lungs and result in injury to other body systems. VVV 000010875 -23 Draft 11/30/89 INHALATION EFFECTS o Excessive vapor concentrations are attainable and could be hazardous on single exposure. o Signs and symptoms of excessive exposure may be central nervous system effects such as sleepiness and unconsciousness. o Nay cause irregular heartbeats, especially under conditions of stress. SUBCHRONIC EFFECTS (TARGET ORGAN) o Repeated excessive exposures may cause liver and kidney effects. CHRONIC EFFECTS/CARCINOGENICITY o Has been shown to cause cancer in laboratory animals. o Is listed as a potential carcinogen by IARC. [continuation of same section] Background Toxicoloelcal Information ACUTE ORAL EFFECTS Single dose oral toxicity is low; the LD50 in rats given the material as a 10% corn oil solution was 1870 mg/kg for males and 3730 mg/kg for females. Liver necrosis was observed in survivors. SKIN EFFECTS The material was only slightly irritating to rabbit skin. The P.I. Score is 0.6 out of 6.0. The potential for absorption throught the skin in acutely toxic amounts is low; the dermal LD50 in rabbits is 20,000 mg/kg. EYE EFFECTS The material was slightly irritating to the rabbit eye. P.I. Score is 18 out of 110. The ACUTE INHALATION Hie 4-hr LC50 in rats was 2500 mg/kg (357 ppm). CNS depression would be expected. May be a cardiac sensitizer based on structural analogy. SUBCHRONIC EFFECTS Repeated inhalation exposure of rats for four or seven hours per day for eight days at 1000 ppm resulted in ataxia, decreased body weight, increased SGPT, and caused increased relative liver and kidney weights with accompanying histologic changes of an adaptive nature. A two-week oral gavage study in rats given 300 mg/kg/day showed hepatic hypertrophy in females but not in males. VVV 000010876 24 Draft 11/30/89 CHRONIC EFFECTS/CARCINOGENICITY A bioassy was conducted by gavage in rats given 60 or 150 mg/kg/day and mice at 230 or 550 mg/kg/day. Both rats and mice showed evidence of increases in hepatocellular carcinoma and adenoma. The doses did not exceed the MTD and the material is listed as a potential carcinogen by IARC. MUTAGENICITY The material was negative in the Ames test. It bound covalently in vivo to DNA, RNA and tissue proteins from rats and mice when injected i.p. D. Section 4: FIRST AID PURPOSE: The HCS requires that MSDSs include appropriate emergency and first aid procedures (MANDATORY). This section should provide instruction, in lay language, when the results of exposure require immediate treatment (first aid) and when simple measures may be taken before professional medical assistance is available. First aid procedures should be brief and easily understood by any untrained individual. SCOPE: Provide instructions by route of exposure (RECOMMENDED). Use subheadings to indicate the procedure for each route (e.g., inhalation, skin, eye and ingestion). Arrange these subheadings in the same order as those in the Potential Health Effects section, if appropriate (RECOMMENDED). Include simple remedial measures (such as washing contacted area, removing of clothing, or removing the exposed individual) if it will lessen exposure (RECOMMENDED). If applicable, include information on first aid for exposures that result from a specific method of handling as opposed to the toxicity of the material (e.g., frost bite from cryogenic liquids, or thermal burns from molten solids) (RECOMMENDED). Include any known antidotes that may be administered by a lay person (RECOMMENDED). List them under the subheading ''ANTIDOTES" or within the appropriate route of exposure. -25- VVV 000010877 Draft 11/30/89 Few specific antidotes and treatments for excessive exposure are known for most chemicals; even fewer are suitable for administration by lay persons. There are, however, some measures that may.be useful to a general audience. Note any antidotes that require special training to use (RECOMMENDED). EXAMPLE for cyanides and cyanide-like substances: Antidote: Always have on hand a cyanide first-aid kit. Break an amyl nitrite pearl in a cloth and hold lightly under nose for 15 seconds. Repeat five times at about 15 second intervals. Call a physician. Use of "No Antidote Known" is not recommended as this may create confusion regarding the toxic potential of the material. Indicate whether immediate medical attention is required and if delayed effects can be expected after exposure. When there is no specific information, the following types of information should be cited, based on sound professional judgement: o Removal of exposed individual from area (to fresh air) o Removal of material from individual o Advice on removal and handling of contaminated clothing and shoes o Advice on whether to contact a physican In certain cases, it may be desirable to acquaint the physician or medical professional with an antidote or with a specific form of medical management. This can be done through a separate "NOTE TO PHYSICIANS" included within the First Aid section of the MSDS or under the specific area of first aid treatment (e.g., ingestion, skin contact) not TO PHYSICIANS PURPOSE: This subsection conveys additional information on specific treatments. It is intended for use by medical professionals following an exposure and may be written in medically technical language. VVV 000010878 -26 SCOPE: Draft 11/30/89 The information contained under "NOTE TOPHYSICIANS" can relate to both Immediate and delayed effects. The information can address both treatoent/therapy and diagonostic procedures. Some considerations include: o Symptoms are presented in the Potential Health Effects section. Additional information may be presented here. Symptoms detectable only by clinical testing should be addressed here. Delayed effects may also be highlighted here. o Recommend specific procedures for treatment. This would include details on emesis or lavage, antidotes, contraindications. o For mixtures, discuss symptoms/treatment for the material and any components of health concern. List of possible "aggravated medical conditions" may be placed in the "NOTE TO PHYSICIANS" since knowledge of such conditions involves a medical judgement. o When there is no specific information available, use statements of the following type: Treat symptomatically Treatment may vary with condition of victim and specifics of incident. EXAMPIZ: Note to Physician for corrosive and toxic gas NOTE TO PHYSICIAN o Any inhalation of this gas requires a period of bed rest and observation. A significant exposure should require hospitalization under medical observation for a period of 48-72 hrs. Delayed pulmonary edema and other respiratory effects may davelop in that time period. o Oxygen, intermittent positive pressure breathing, assisted respiration, and steroid therapy should be considered in treatment. Physical exertion potentiates the effects during the first 24-72 hrs. o If burn is present, treat as any thermal bum, after decontamination. VVV 000010879 -27 urart 11/30/89 E. Section 5: FIRE AN" CTPT.ngTOM PURPOSE: The Information contained in this section is MANDATORY. It should describe: o the fire and explosive properties of the material, o appropriate extinguishing media, o basic fire fighting guidance. This section is intended for employees, emergency responders, and occupational health and safety professionals. Language should be simple and easily understood. It should convey the properties of the material that a trained fire fighter needs to know before fighting a fire. SCOPE: FLAMMABLE PROPERTIES Certain physical and chemical properties describe the potential fire hazard of the material. Most properties are numeric (like flash point) and can be presented in tabular form. Present all values with both the appropriate units of measurement and where appropriate, the conditions of measurement. It is recommended that all temperature values be expressed in degrees Farenheit to be most useful for emergency responders in the United States. An additional value expressed in degrees Centigrade can be useful on data sheets intended for distribution to other countries. Include the following: o flash point (MANDATORY) and method (RECOMMENDED) o upper & lower flamable (explosive) limits in air (RECOMMENDED) o autoignition temperature (RECOMMENDED) o flaonabillty classification, as defined by 29CFR 1910.1200 (RECOMMENDED) o flame propagation or burning rate of solid materials (RECOMMENDED) o known or anticipated hazardous products of combustion (OPTIONAL) o properties of both flammable and nonflammable materials that may initiate or uniquely contribute to the intensity of a fire (RECOMMENDED) For solids: o potential for dust explosion o reactions that release flammable gases or vapors o fast or intensely burning characteristics For liquids: o potential for release of flammable vapors -28- VVV 000010Q80 Draft 11/30/89 EXAMPIE for flammable liquid: Vapors may travel considerable distance to ignition source and flash back. Text should also cover nonflammables that could contribute unusual hazards to a fire, such as strong oxidizing and reducing agents or peroxide formers. EXAMPIf for a certain acid: Hydrogen gas is released upon contact with common metals. EXAMPUE for alkali metal: Hydrogen and heat is released upon contact with water. EXAMPIE text for an oxidizer: Strong Oxidizer. Contact with combustible materials may cause fire. SCOPE: Reactivity hazards that enhance the fire and explosion potential should be stated here. Dangerous or explosive reactions with specific chemicals should be covered in the Reactivity Section. The potential release of unique toxic products of combustion, such as carbon monoxide should be mentioned. Since a variety of combustion products are possible from a given material, depending on fire conditions, a brief statement may be all that is appropriate. General terms such as "acrid fumes including...,1' "possible cyanide containing fumes" or "highly toxic fumes of..." are appropriate when the material is likely to emit potentially hazardous combustion products. The MSDS should identify likely toxic components if the "smoke" (products of combustion) could be an unusually greater hazard than might occur in a typical structural fire. ^ o00Ol08Sl EXTINGUISHING MEDIA List the proper extinguishing media. Logic should be similar to that found in the latest edition of the NFPA guide, "Fire Protection Guide on Hazardous Materials." This reference contains both extinguishing -29- Draft 11/30/89 media and fire fighting information for a number of specific chemicals. It is written so that the information can also be easily applied to chemicals not specifically listed in the text. Possible reactions of the subject material with the extinguishing media should be covered, such as using water on water-reactive materials or spattering and frothing from spraying water or foam on-.high flash point liquids. EXAMPLE for flammable organic liquid: Use foam, C02, or dry chemical extinguishants. Water may be ineffective. Water spray should be used to keep fire exposed containers cool. SCOPE: FIRE FIGHTING INSTRUCTIONS Instructions should be directed at protecting lives of those in the fire area (including firefighters), noting unusual impact on the environment and minimizing property loaa. Because you cannot anticipate the size of the fire, the amount of material(s) involved, the immediate surroundings and other factors, guidance should reflect the specific properties of the material. Text should cover appropriate actions for materials that emit highly toxic fumes where direct contact with the material would be hazardous, or when the material Is explosive or an unusual fire hazard. Special environmental warnings, such as toxicity of fire water run off, should be made when appropriate. KXAHPI for a flammable gas: Stop flow of gas before attempting to extinguish fire. Gas could form explosive mixture and reignlte. EXAMPIS for explosive or highly toxic materials: Evacuate personnel to a safe area. ooooiGaez. 30- Draft 11/30/89 racAMPTJt for a heat: sensitive material: Fight fire from maximum distance. Use extreme caution, as heat may decompose material and rupture containers. EXAMPI for a reactive monomer: Vapors are uninhibited and can cause plugs in relief vents. For all fires, minimum protection stated in the MSDS text should include self-contained breathing apparatus (SCBA) and full protective equipment (Bunker Gear). For specific materials where this is not adequate protection, the text should note the specific hazard and direct the reader to the Personal Protective Equipment (PPE) subsection where the PPE logic is explained for emergencies. EZAMPIZ for most hydrocarbon flaamables with no unusual toxicity: Keep personnel removed from and upwind of fire. Wear full protective equipment: eye/face (shield), body (full Bunker Gear), respiratory (SCBA). Cool container with water spray. The NFPA "Fire Protection Guide on Hazardous Materials" has fire fighting guidance for many specific materials as well as for many classes of materials. Much of the text used in the NFPA reference is suitable for the MSDS. Where appropriate, include advice on fighting small and large fires. This section is not intended to deal with proper handling and storage of flaamables. Such information belongs in the Storage *nri Handling section. F. Section 6: RRACTIVITT Purpose: The OSKA HCS requires disclosure of potential reactivity hazards (MANDATORY). This can be accomplished by describing the conditions that could result in a potentially hazardous chemical reaction (RECOMMENDED). This section is intended for employees and occupational health and safety professionals. Some information will also be useful for emergency responders. vvv ooooioaaj 31 Draft 11/30/89 Scope: The Information presented in this section should be based, where available, on specific test data for the material. This section may also contain the specific data. However, the information may also be based on general data for the class or family of chemical if it adequately represents the anticipated hazard of the material. ,This section should address the following elements: Chemical stability: Indicate if the material is stable or dangerously unstable under normal ambient and anticipated storage and handling conditions of temperature and pressure (RECOMMENDED). Conditions to avoid: List conditions such as heat, pressure, shock, or other conditions that might result in a hazardous situation (RECOMMENDED). Incompatibility with other materials: Address chemicals and other materials that the product could react with to produce a hazardous situation (e.g., explosion, release of toxic or flammable materials, liberation of excessive heat). In determining incompatibility, consider the materials, containers, and contaminants that the product might be exposed to during transportation, storage, and use (RECOMMENDED). Hazardous decomposition products: List known and reasonably anticipated hazardous materials produced as a result of oxidation (burning), heating, or reaction with another material, including the production of flammable and toxic materials (RECOMMENDED). Hazardous polymerization: State if the material will polymerize releasing excess pressure, heat, or creating other hazardous conditions. Also state under what conditions the hazardous polymerization could occur (RECOMMENDED). 6. Section 7s SPILL Atm tjcat MtSPQNSE PURPOSE: This section contains information for responding to spills, leaks or releases in order to prevent or minimize the adverse effects on persons, property, and the environment. It is intended to be used by emergency responders and environmental professionals. vvv 000010884 32 Draft 11/30/89 SCOPE: Include Information on containment techniques, cleanup procedures, equipment and other emergency advice relating to spills and releases (MANDATORY). Include information specific to spill and leak response (RECOMMENDED). Vhere no special instructions are necessary, it may be useful to indicate that fact and reference other sections which could be helpful. Containment techniques could include diking or capping procedures. Clean up procedures and equipment could include neutralization and decontamination techniques, sorbent materials, sweeping or vacuuming techniques, and the use of nonsparking tools and equipment. Personal protective equipment is specified in the Personal Protection/Exposure Controls section. Other emergency advice would include evacuation procedures and special instructions necessary to protect the health and safety of the responders and others, as well as the environment. Examples could include removal of ignition sources for flammable materials, warnings to stay upwind, and securing the area. There may be specific reporting requirements associated with spills, leaks, or releases. It may be useful to reference such reporting requirements in this section or in the separate Regulatory section (OPTIONAL). H. Section 8: PERSONAL PROIECTICH/EXPOSORE CONTROLS Personal Protective Equipment (PPE) PURPOSE: This subsection provides guidance for selection of personal protective equipment (PPE) needed to minimize the potential for illness or injury due to exposure from the material. This section is intended for employees, occupational health and safety professionals, and emergency responders. SCOPE: Recommend PPE for each route of exposure - inhalation, skin and eye/face (MANDATORY). Note specific regulatory requirements for PPE (e.g., TSCA 5(e), OSHA chemical specific standards) Emphasize the importance of minimizing or preventing contact or exposure to the product. VVV 000010885 33- Draft 11/30/89 EXAMPLES: Always wear a positive pressure air supplied respirator when handling this material. Wear ... , as appropriate, to prevent ANY contact with this material. Base recommendations on: o the specific properties and hazards of the subject material; o coupled with a general note on the circumstances requiring the recommended PPE. Assume that the intended audience is trained in principles of proper selection and use of the PPE and can apply the training to the specific, local conditions of product handling or emergencies. Proper PPE training is an OSHA requirement for PPE wearers and program administrators. Since the preparer does not know the local conditions of use and exposure (e.g., quantity of product handled, process equipment, ventilation), PPE guidance can, for the most part, only be of a general nature. You may, however, provide some specific guidance on PPE based on the properties of the material. The text should cover PPE appropriate for: o normal use and handling where the exposure potential has been determined. o emergency situations where the potential for exposure is not well defined. This section should contain guidance for PPE selection for fire fighting, spill clean up, and other emergencies (RECOMMENDED). The Fire and Explosion, and/or Spill and Leak Response sections should warn of the general need for PPE and refer the reader to the PPE section for instruction. 34 Draft 11/30/89 Fire fighting now universally requires full respiratory protection and bunker gear to protect the wearer from a variety of hazards associated with fire fighting. If the material has some toxic hazard that could render the bunker gear Inadequate under some conditions, state this fact in the Fire and Explosion section, and refer the reader to the PPE section for special guidance. Similiarly in a spill, proper PPE selection would depend on a number of circumstances, such as location and size of spill. Basic PPE guidance text in a MSDS needs to be reviewed before PPE decisions are made. Recommend, when known, materials of construction, such as neoprene or butyl rubber, that provide the best chemical barrier. Conversely, identify materials known to be unacceptable. Specify PPE for handling radioactive materials or materials that routinely present a thermal hazard (e.g., molten chemicals, cyrogenics). Note the specific regulatory requirements on PPE for the subject material (MANDATORY). DATA ELEMENTS: Eve/Face Protection Specify type of eye protection, safety glasses, goggles, and face shield based on the potential hazard of contact. Include a general note on the circumstances requiring the PPE. For a corrosive material, the text would require goggles and face shield when there is potential for contact. KXAMPU for a corrosive material: Wear safety glasses. Wear coverall, chemical splash goggles and face shield when eye and face contact is possible due to splashing or spraying of material. Skin Protection Recommend when known, the best barrier material (such as butyl rubber or neoprene) for PPE. Base the recommendation on laboratory permeation data, or appropriate field experience. -35- VVV 000010887 Draft 11/30/89 What to wear (e.g., gloves, boots, bodysuit) can only be specified In a general way. Allow the reader to make decisions based on both MSDS data and an assessment of the local exposure potential. What should be stressed is the relative importance of preventing contact. exampie Wear as appropriate, to prevent ANY contact. Wear ...., as appropriate, when possibility exists for contact with sprayed material. Respiratory Protection Identify different types of respiratory protection for different conditions. The text should indicate if air purifying respirators may be used under certain circumstances. It should also specify the proper purifying element (cartridge or canister). As a reminder to the reader, state the limitations of the different types of air purifying respirators and the need to use positive pressure air supplied respirators at conditions exceeding the limits of air purifying devices or unknown contaminant levels; assume that the reader is trained in respirator selection and use, as required by federal regulations. ITAMPTr A NIOSH/MSHA approved air purifying respirator with an organic vapor cartridge or canister may be permissible under certain circumstances where airborne concentrations are expected to exceed exposure limits. Protection provided by air purifying respirators is limited. Use a positive pressure air supplied respirator if there is any potential for uncontrolled release, exposure levels are not known, or any other circumstances where air purifying respirators may not provide adequate protection. VVV 00001088b 36 Draft 11/30/89 If an air purifying respirator is not adequate protection, the text should specify a positive pressure, air supplied respirator. Note or reference any respiratory requirements specified by regulation. General Include PPE recommendations on what to wear for any specific operation known to occur repeatedly with the majority of users, such as unloading a pressurized tank car, or spraying the material. Although optional, this information is valuable for high exposure potential operations with highly toxic materials. For example, you could recommend an air supplied respirator and full protective gear for an operation that normally presents virtually no exposure but has a potential for an uncontrolled release. Engineering Controls PURPOSE: This subsection discusses the engineering controls needed to help minimize chemical or physical hazards. This information is intended for employers and occupational health and safety professionals. SCOPE: The USDS must mention any generally applicable control measures, including engineering controls, that are known to the MSDS preparer (MANDATORY). This subsection contains any recommended engineering controls including ventilation needs and special process conditions needed to control exposures or other hazards of the material during its normal anticipated use. You may want to include a statement such as "no specific controls are needed" for relatively innocuous materials or "handle only in fully enclosed systems and equipment" for materials that pose a high degree of hazard. Other good engineering practices may be included on an MSDS, such as use of safety showers and eyewashes. EZAMPIE: Use exhaust ventilation to keep airborne concentrations below exposure limits. State the goals and limitations of ventilation systems and other engineering controls. Design criteria usually cannot be specified in an MSDS because of its complexity. This information is more appropriate in a technical design bulletin. -37- VVV 000010899 Draft 11/30/89 Exposure Guidelines Purpose: This subsection identifies established exposure guidelines for the product and/or its components (MANDATORY). The information is intended for occupational health and safety professionals and employees.: Scope: OSHA PELs, AC6IH TLVs and established company exposure guidelines must be listed in the MSDS for a pure material and for the components of a mixture (MANDATORY). Include other exposure guidelines at your discretion. List the exposure guidelines in this specific section of the MSDS if not already listed in the Chemical/Hazardous Components section (see options at end of this section). Exposure guidelines are numerical entries depicting an airborne concentration of a specific material and a time frame of exposure to that material. Indicate the units used to describe both the airborne concentration and the time frame (usually eight-hours, 15 minutes, or ceiling). Exposure guidelines should include the "skin notation" qualifier where applicable. List the exposure guidelines for each component of the mixture as appropriate (MANDATORY). Certain chemical mixtures, such as a product that has a solvent base of several different hydrocarbons, contain components that may act upon the same organ system. The combined health effects may be additive. For these mixtures, refer to sources of appropriate explanations and formulae for determining the exposure limit for mixtures (RECOMMENDED). EEAHPIS: See 29CFR 1910.1000 (d) (2) and ACGIH Threshold Limit Values and Biological Exposure Indices booklet (Appendix C) for the determination of exposure limits for mixtures. List mandatory exposure guidelines first, followed by any optional exposure guidelines (RECOMMENDED). It is not mandatory to mention that exposure guidelines are unavailable for the material or components of the mixture; however, providing this information would let the reader know that the lack of an exposure guideline was not an omission. -38- 00001^0 Draft 11/30/89 OPTION: Exposure guidelines placed with components Section 2: Chemical (or Hazardous) Components Component Cas No. % (by wt.) OSHA TWA STEL Exoosure Guidelines ACGIH XYZ Comoanv TWA STWL TWA STEL Units Chemical A xxx-xx-x 40 100 150 100 150 50 100 ppm Chemical B xxxx-xx-x 30 50 N.E. 50 N.E. 50 N.E. ppm Chemical C xxxxx-xx-x 20 200(s) 250(s) 200(s)250(s) 200(s)250(s)ppm Chemical D xxxx-xx-x 10 N.E. N.E. 250 N.E. 250 N.E. Dorn N.E. * Not Established (s) - Skin OPTION: Exposure guidelines in Personal/Exposure Controls Section Section 8: PERSONAL PROTECTION/EXPOSURE CONTROLS Exposure Guidelines: Chemical A - TVA 100 ppm, STEL 150 ppm (OSHA AND ACGIH) * TWA 50 ppm, STEL 100 ppm (XYZ Company) Chemical B - TWA 50 ppm, STEL N.E. Chemical C - TWA 200 ppm, STEL 250 ppm (skin) Chemical D - TWA 250 ppm (ACGIH and XYZ Company) N.E. * Not Established -39- VVV 000010891 Draft 11/30/89 I. Section 9 : STORAGE AND HAwnT.TMG Storage PURPOSE: Information about appropriate storage practices is mandatory. State the information in lay language (RECOMMENDED). This information is directed to employees, including those involved in storage or transport of the material. SCOPE: Emphasis should be placed on avoiding unusual or unique conditions that could damage physical structures and equipment, as well as individuals working in contact with the stored material. Consider explosive atmospheres, corrosive conditions, and flammability hazards. Emphasis should be placed on avoiding conditions that could damage or destroy the product and its container. Consider incompatible materials, evaporative conditions, and ambient conditions (e.g., pressure, temperature, humidity, vibration). You may also include information on conditions necessary to maintain the integrity of the material (OPTIONAL). Handling PURPOSE: This subsection provides guidance on safe handling practices that will minimize the potential hazards from the subject material. The information is intended for employees, occupational health and safety professionals, and employers (customers). SCOPE: Emphasize precautions thAt are proper for the unique properties of the material rather than reviewing general good industrial practices. Note or reference specific federal regulatory requirements on the safe handling of the material (MANDATORY). List handling practices that: o minimize contact between the worker and the material o minimize continued contact after the material has been handled o minimize risks from fire for flammables and combustibles or dangerous reactions with incompatible materials o minimize release of the material to the environment WV 000010892 40 Draft 11/30/89 Include general warnings on what practices to avoid or restrict. Standard precautionary label statements are suitable text for this section. (Refer to American National Standard for Hazardous Industrial Chemcicals Precautionary Labeling: ANSI Z129.1-1988.) EXAMPI of general warning to prevent overexposure: Do not breathe dust or vapor. Avoid contact with skin, eyes or clothing. EXAMPLE of hygiene recommendations to prevent continued exposure: Wash throughly after handling. Destroy contaminated shoes. Include handling practices such as how to prevent vapor release, the need for a totally enclosed system and other useful practices to avoid while unloading. mnpri Loosen closure cautiously before opening. Avoid dust generation. To prevent injury, include statements about use of non-sparking tools, explosion proof equipment and grounding when handling flammables. ezampu Ground containers when pouring. 41 VVV 000010893 Draft 11/30/89 List which practices should be followed to avoid dangerous reactions, such as inert blanketing, using oil in equipment for strong oxidizers, or opening drums that could be under pressure. example If frozen, do not use steam to liquify. Use only clean, dry utensils in handling. Include precautions about handling molten or hot materials, and cryogenics. Generally keep the precautionary statements simple and relate them to a specific property of the material. EXAHPUS for physical states such as compressed gas, dusty solid, volatile liquid, or handled molten: Handle [specific gas] only in a totally enclosed system EXAMFU for a chemical property such as flammability or reactivity: Use of non-sparking or explosion-proof equipment may be necessary depending upon type of operation KXAHPUB for toxic properties such as corrosive, readily absorbed through the skin or highly toxic via inhalation: Use adequate ventilation to keep airborne concentrations below exposure limits J. Section 10; PHYSICAL Aim CBPfTCAT. PROPERTIES PURPOSE: This section identifies the physical and chemical properties that characterize the material (MANDATORY). This information is useful in determining proper product handling procedures. All data sheet users may use some or all of this information. -42- VVV 000010894 11/30/89 SCOPE: List and include data, when known, on the following characteristics: Recommended Characteristics Appearance Odor Physical state (recommended, if not described Material Identification) PH Vapor pressure (include reference temperature) Vapor density Boiling point Freezing/melting point (specify) So'ubility in water Specific gravity or density in These characteristics should always appear on an MSDS. Clearly identify if specific characteristics do not apply or for which data are not available. Other properties may be specific to only certain materials. When applicable, include data on the following characteristics: Optional Characteristics Softening point Evaporation rate Viscosity Bulk density % volatile Octanol/water partition coefficient Saturated vapor concentration Molecular weight You do not need to list these characteristic names if data are unavailable. Identify appropriate units of measurement for characteristics (see discussion in Chapter 4 on Units of Measurement). K. Optional Section: TOXICOLOGICAL INFORMATION PURPOSE: This section provides information on toxicity testing of the material and/or its components (OPTIONAL). It is intended for medical professionals, occupational health and safety professionals, and toxicologists. SCOPE: This section may contain background data (either positive or negative) used to determine the hazards presented in the Potential Health Effects section. Include studies of questionable human relevance if not -43- VVV 000010695 Draft 11/30/89 mentioned in Potential Health Effects and if discussion will assist in the evaluation of the material. The following data types could be addressed: o Acute data (e.g., LD50 (oral & dermal), irritation scores, LC50 (inhalation)) o Subchronic (e.g., for determination of target organs, effect and no-effect levels, species differences, type of effect) o Special Studies such as: Epidemiology Carcinogenicity Teratogenicity Reproductive effects Neurotoxicity Mutagenicity Other studies relevant to material In some cases there may be a wealth of testing on the components of material, or on the material itself. If so, it may be desirable to summarize the results either by route of exposure or end-point of the test, whichever is most relevant. L. Optional Section: ECOLOGICAL INFORMATION Ecotoxicological Information PURPOSE: The information in this subsection is intended to help environmental professionals predict how the material will interact with living organisms following its release into the environment. It may also be useful in treatment of wastes (OPTIONAL). SCOPE: List effects on plants and animals such as fish, birds, and other aquatic and terrestrial species and plants. You may want to include a summary or environmental assessment statement. Consider including data on: o algal and lemna growth inhibition o acute and long term toxicity to fish and invertebrates o toxicity to plants (aquatic and terrestrial) o acute and dietary toxicity in birds Chemical Fate Information PURPOSE: This subsection contains information that can be used by environmental professionals to determine how long a material may persist and how it will be distributed in the environment or waste treatment systems. This -44- vvv 000010896 Draft 11/30/89 SCOPE: information will help the reader determine environmental persistence, treatability of the material, and measures useful for spill control. Include information on environmental degradation studies, oxygen demand, soil mobility, reaction rate studies and bioaccumulation/bioconcentration in organisms., M. Optional Section: REGULATORY INFORMATION Transportation PURPOSE: This subsection provides basic regulatory transportation information. This information will help a knowledgeable user prepare a material for shipment and is important to the employer, distributor, internal and customer transportation/shipping departments and emergency responders. SCOPE: Include the U.S. Department of Transportation (DOT) classification/description necessary to ship a material within, to, or from a place in the U.S. This section is not intended to contain every regulatory detail involving the transportation of a material. International regulatory transportation information may also be included. Include DOT basic description consisting of: o Hazardous Materials Description/Proper Shipping Name o Hazard Class o Identification Number Indicate if a product is not regulated by DOT or if the classification changes based on quantity, packaging or method of shipment. An optional way to provide transportation information is to include a telephone number to contact for special instructions. Additional elements may include: o Other DOT requirements such as technical names, hazardous substances/reportable quantities, modal restrictions, packaging, labeling, or exemptions, o Classification/descriptions under International Transportation Regulations including : IMO (International Maritime Organization) regulations pertaining to water shipments VVV 000010897 45 Draft 11/30/89 ICAO (International Civil Aviation Organization) and IATA (International Air Transport Association) regulations pertaining to air shipments Transport Canada regulations for shipping ADR (European Agreement Concerning the International Carriage of Dangerous Goods by Road) RID (European Agreements Concerning the Carriage of Dangerous Goods by Rail) U.S. Federal Regulations PURPOSE: This subsection provides information on the regulatory status of materials (including their components) and their regulated uses. The information will be useful for compliance with various health, safety and environmental laws and regulations, and is aimed at employers and regulatory compliance personnel. SCOPE: Address U.S. federal regulations that you wish to cover. Examples are: OSHA, TSCA, FIFRA, CERCLA, EPCRA (SARA Title III), and CAA, CWA, SDWA, CPSA, DEA and FDA/USDA. (Acronyms are defined in the glossary.) Address the status of the material and its components under OSHA with a simple statement about whether the product is considered to be hazardous as defined by the OSHA HCS (29 CFR 1910.1200) or a chemical specific standard. (RECOMMENDED) This information may also be included in the section on Hazardous Components. Indicate whether the material complies with TSCA Inventory requirements (RECOMMENDED). Provide the status of the material under other sections of TSCA (OPTIONAL). These sections may include but are not limited to the following: o 5(a)(2): Significant New Use Rule (SNUR) o 5(e): Final Consent/ Orders o 5(h)(3): Research end Development Limitations o 12(b): Export Notification Requirements o Exempt: Exempt from TSCA, registered pesticide under FIFRA List the reportable quantity of the material under CERCLA (RECOMMENDED). If the product does not have a reportable quantity, include a statement to that effect. 46 vw 000010898 Draft 11/30/89 Provide information on the material and/or its components as defined under SARA Title III (RECOMMENDED). These sections may include the following: o Section 302 Extremely Hazardous Substances: Provide the chemical identity of the listed substance, its threshold planning quantity (TPQ) and its reportable quantity (RQ). o Section 311/312: List the hazard class(es) of the material. o Section 313 Toxic Chemicals: Provide the chemical identity of the listed substance, its CAS number or other designated reference, and its percent (%) by weight. International Regulations PURPOSE: This subsection provides information on materials to those exporting outside the U.S. Its purpose is to help in complying with various health, safety, environmental and classification requirements. This information is directed at employers and regulatory compliance personnel. SCOPE: This subsection may include information on WHMIS, EEC, EINECS, AICS and Canadian Inventory. The following elements may be included in this section: 1. WHMIS: ^hazard class(es) -hazard symbol(s) -trade secret notices 2. EEC: -Risk and Safety (R&S) statements hazard symbols 3. EINECS: -a statement that the product complies with the provisions of the European Inventory 4. AICS: -a statement that the product complies with the provisions of the Australian inventory 5. Canadian Inventory (CEPA): -a statement that the product complies with the provisions of the Canadian inventory 6. MITI - a statement that the product complies with the provisions of the Japanese inventory -47- VVV 000010899 Draft 11/30/89 Stata Regulations PURPOSE: This subsection provides information required by state right-to-know and other related state laws. When providing information, you can assume that the audience is relatively well versed on the subject. Audiences include occupational health and safety, and environmental professionals within your own company or your customers. Generally, the information will be specified by regulation and somewhat technical even though the audiences may be non-technical. SCOPE: Most states have adopted the OSHA Hazard Communication Standard, but many have additional information requirements. When evaluating the regulatory requirements for your materials, consult the state regulations for the states in which you manufacture or market the material. Some state agency contacts are listed in Appendix 3. Types of state right-to-know requirements are described below. Do not consider this to be a complete presentation of the requirements. For more information, you should contact the states that affect your business. o Many states require inclusion of state listed substances on the MSDS. There are often requirements to list these substances at below the OSHA KCS concentration levels. (Massachusetts, Pennsylvania, Rhode Island) o States may require disclosure of non-hazardous ingredients (Pennsylvania). o States may require specialized data requirements. Examples are volatile organic compounds or VOCs (California) and environmental effects (Vermont). N. Optional Section: SUPPTJMKNTAL INFORMATION Waste Management Information (Disposal) PURPOSE: This subsection provides information that may be useful in the proper disposal of the material. The information is primarily intended for environmental professionals who are responsible for waste management activities. VVV 000010900 48 Draft 11/30/89 SCOPE: Designate whether or not the material (as waste) is a hazardous waste according to 40 CFR 261. If the waste material is designated a hazardous waste, include: o USEPA hazardous waste number(s) o description of the waste o 'hazard code (I, C, R, E, H, or T) o DOT hazard class code (01 through 16) If the material (as waste) exhibits the characteristics of EP (extraction procedure) toxicity (40 CFR 261.24), and the concentrations) of the contaminant(s) listed for USEPA hazardous waste numbers D004 through DO17 is (are) known, such information may be presented in this section. Properties, characteristics and other descriptors, such as heat value, particle size and volatile organic compound content, that are useful information in the filing of hazardous waste profile forms and authorization request forms, should be presented in the Physical end Chemical Properties section of the USDS. If the waste material is classified as an acute hazardous waste (hazard code H), disposal of the empty container and/or the container rinsate may also be regulated. Include information for handling this disposal. The MSDS should advise the reader that waste disposal regulations within a state or locality may be more restrictive or otherwise different from federal regulations. A typical statement on the MSDS for alerting the reader may read: Please be advised that state and local requirements for waste disposal may be more restrictive or otherwise different from federal laws and regulations. Consult state and local regulations regarding the proper disposal of this material. The MSDS should also alert the reader that any changes to the material as received (e.g., chemical additions to the material, processing of the material) may make the waste management information in the MSDS inappropriate. A typical statement on the MSDS may read: Chemical additions, processing or otherwise altering this material may make the waste management information presented in this MSDS incomplete, inaccurate or otherwise inappropriate. VVV 000010901 -49- Draft 11/30/89 Statements that provide obvious information such as "Dispose in accordance with all applicable laws and regulations" do not add much to the MSDS. The MSDS writer should also consider other pertinent * information and/or references to regulations promulgated under the Clean Water Act, the Federal Insecticide, Fungicide and Rodenticide Act, and the Federal Water Pollution Act, when the handling/management of the material as waste is impacted by such regulations. Label Text PURPOSE: Label text is written using information provided in the MSDS and typically uses language recommended in the ANSI standard for Hazardous Industrial Chemicals*' Precautionary Labeling (ANSI 2129.1*1988). Some companies will use label statements of hazards as part of the Emergency Overview and may not choose to repeat them in an optional label subsection. Other companies may wish to display their label statements as a service to customers or to help ensure label text will be consistent with MSDS text. SCOPE: Label text consists of the statements of hazard and accompanying associated statements that have been selected from information in the MSDS for use on the label. Hazard Hating Systems PURPOSE: This subsection provides a location for hazard rating codes or symbols using one or more rating systems. This information is intended solely for the use of individuals trained in a particular system. SCOPE: Several different hazard rating systems have been developed, and differences exist among the systems. Typically these systems include acute health hazards, flammability and reactivity, and may also include other hazards. Different systems can frequently result in different ratings, causing potential confusion to readers not familiar with a system. If an MSDS contains a hazard rating code or symbol, you should clearly identify which system was used to generate the rating. Internal company codes should not be used on MSDSs in general distribution. Hazard ratings may also be included as an independent element in the Regulatory Information section. The MSDS may contain a disclaimer Indicating that the rating is intended only for individuals trained in the use of that particular system. 50- VVV 000010902 Draft 11/30/89 Some organizations may require that a company register its material with them before using the rating on the MSDS. CHAPTER 6: EVALUATING THE COMPLETED HSDS Once the text for each section of the MSDS has been drafted, the entire document must be evaluated. The following items need to be considered: o Is the data/information included in each section consistent with the data/information in other sections? For example, is a high vapor pressure value indicated in the Physical and Chemical Properties section properly reflected by appropriate comments in F*re and Explosion. Reactivity, or other sections. o Does the data/information included on the MSDS accurately reflect the data on hand and the writer's professional judgement? o Is the data/information included on the MSDS consistent with the data/information included in other company literature, such as technical bulletins? o Is the data/information included on the MSDS current? The HCS requires that the information on the sheet be current. Significant new hazards of a material must be included on the MSDS within 90 days from when the company becomes aware of the information. The information must then be communicated to the customer with the next shipment. o Is there a system in place for collection and review of new information, and for updating the MSDS? The responsibilities under the HCS continue after an MSDS has been prepared and issued. It is essential that a system is in place to ensure that each MSDS is current. o Have you followed the principles for effective communication in design* appearance and language use? 51- VVV 000010903 Draft 11/30/89 References [not yet complete] Occupational Safety and Health Administration's Hazard Communication Standard, 29 C.F.R. 1910.1200 et seq. American National Standard for hazardous industrial chemicals - precautionary labeling; ANSI Z129.1-1988. National Fire Protection Association's Fire Protection Guide on Hazardous Materials; 9th Edition; 1986. American Conference of Governmental Industrial Hygienists' Threshold Limit Values and Biological Exposure Indices for 1989-1990. VVV 000010904 52 FORMS AND EXAMPLES [To Be Added] 5-3 VVV 000010905 S1BMT GLOSSARY INTRODUCTION The glossary defines tones used in this Guideline m well as com terae rwwnly used In NSDSs. The glossary alto offers suggested alternatives for som technical reran. The glossary contains aany rogulstory definitions (currant os of 1/90). Uhere aultiple rogulstory dsfinitons exist (e.g., DOT, OSHA, EPA), the OSHA definition presentod first, others are given as appropriate. Non*regulatory definitions wars choaan froa a side variety of reference asterisis ecaonly used in the hssard craauiieatiens profession as well as froa other caweniy used In the hazard c--aaiicsltons profession as well as froa other chsaiesl'related regferancss. There ere soae teraa whose definitions have been developed by the authors of this Guideline. Although these uni** definitions convey the concepts presented In the text of Guideline, they aae not aaant to be used outside of the context of the Guideline. vw 000010906 The terms included in the glossary that are protected by copyright are being reprinted with permission of the sources listed below. The footnote numbers are shown on the left. [3J- American National Standard for Hazardous Industrial Chemicals - Precautionary Labeling (ANSI Z129.1-1988). <>1988 American National Standards Institute, Inc. [4]- The Condensed Chemical Dictionary (G.G. Hawley 11th ed.1987) 1987 Van Nostrand Reinhold Company. [5]- Websters Ninth New Collegiate Dictionary O 1989 Merriem Webster, Inc. [7]- K. Verschueren, Handbook of Environmental Data on Organic Chemicals (2nd ed. 1983). 4 1983 Van Norstrand Reinhold Company. [8]- Dorland's Illustrated Medical Dictionary (E.J. Taylor 27th ed. 1986) 1988 W.B. Saunders Company [11]- Borland's Pocket Medical Dictionary (24th ed. 1989). 1989 W.B. Saunders Company [12]- NFPA-49, Hazardous Chemical Data. @ 1975 National Fire Protection Association, Quincy, Mass. 02269. This reprinted material is not the complete and official position of the NFPA on the referenced subject which is represented only by the standard in its entirety. VVV 000010907 TERM DEF1KITIOM NSOS GLOSSARY SHflFTT Aeid Acids are Material* which have a pH of 0 to 6. Acid* with pH in the 0 to 2 range are considered corrosive and will cause bums to skina and eyes. Acids will react with alkali Material. [1] ACGIH Anerican Conference of Governmental industrial Hygienists is an organization of professional personnel in governmental agencies or educational institutions engaged in occupational safety and health programs. ACGIH establishes recosmended occupational exposure Units for chemical subetancea and physical agents. See Tiv. (23 Acuta health affect Health effects that usually occur rapidly as a result of short-term exposures, and are of short duration. Examples of scam scuts health effects ere irritation, corrosivity (tissue destruction), narcosis, end death. [13 LAY LANGUAGE DESCRIPTION: 1--mdiete Health Effect Adequate ventilation A condition felling within either or both of tho following categories: (1) Ventilation aufficiont to rarkrora levels of air contaminant below that which nay cause personal injury or illness. (2) Ventilation sufficient to prevent accumjlatlen to o concentration of contaminant vapor in air at a level In excess of 23 percent of the level set for tho loiter fleasable limit. (33 Aerosol A suspension of lipild or solid particles in a gas, tha particles often being in the colloidal else range. Fog end amok# ere emaon snmqilee of natural aerosols; find prays (perftmaa, ineeetieidss, irdialants, anti-perspirents, psfnts, etc.) ere nenmade aerosols. Suspensions of various kinds nay be formed by placing tha components, together with a compressed gee, in a container (bmO). The pressure of tho gee causes the mixture to be released ee a find spray (aerosol) or foam (aerogel) when a valve la opened. (41 AICS Alkali Analgoeia Australian inventory Chemical Sitetaneea. A list fo chemical substances ttfiich nay be used commercially in Australia. Similar to TSCA Chemical Subatanets Inventory. (1] Alkalis (or boeot) ere materials which have pH valuta from 8 to 14. Alkalis with pHs betwain 12 to 14 era cone1dared corrosive and will cause severe damage to skin and eyes. (1] Intangibility to pain without loaa of eonaciouanaM. (51 Antethesis Lota of tarnation with or without leas of consciousness. (53 Antagonist When speaking of health affects It is tho effect of one material or chemical that tsnda to coviterect tha affect of another material or chemical. Literally antagonism mono to work against. (13 Antidote A randy to relieve, prevent or cauitereet the effects of o poison. {23 vvv 00001090a TERM DEFINITION NODS GLOSSARY (Contimed) Page 5 Apnea Article Asphyxia Asphyxiant Aspiration hazard ASTM Ataxia Atrophy Autoignition ioconcontration BCD Tasporary stoppogo of broathlng (1] OSHA dtfinos an artielo as follows: A Manufactured iten: (f) which is foraod to a spaeific shape or design during Manufacture; (i i> which has end use finctiorKs) dependent in idiole or in port upon its shape or design during and use; and (Hi) which does not release, or otherwise result in exposure to a hazardous eheMical, under noraal conditions of use. C6] A lack of oxygen in the blood and tissues, which causes unconsciousness, aay be caused by Materials which interfer with the exchange of oxygen and carbon dioxide (eg. ethylene) or by physical injuries creating strangulation. Cl] LAY LANGUAGE DESCRIPTION: Suffocation A vapor or gas that can cause wwonsciousness or death by suffocation (lack of oxygen), host siaple asphyxiants are harsrful to the body only when they bacons so concentrated that they reduce oxygon in the air (nomelly about 21 percent) to dangerous levels OS percent or lower). Asphyxiation is one of the principal potential hasarda of working in confined and enclosed spaces. (2] LAY LANGUAGE DESCRIPTION: The danger of inhaling liquids into the Itftgs, particularly when unconscious or sent* conscious; a danger tdian inducing veariting. Nay lead to aspiration pnouaonitis, an acute inflaaeation of the lings. (1) Aosriean Society for Testing and Materials la the world's largest source of voluntary consensus standards for Material, products, syetons, and services. ASTM is a resource for aanpling and testing Methods, health and safety aspects of Materials, safe par foraama guidelines, effects of physical and biological agents and chenicals. [2] Loss of reflexes or mukIs coordination. Depending on ausclee affected signs can include - twitching, studying or wsteody walk, shaking, and slurred speech (1] LAY LANGUAGE DESCRIPTION: Leas of Muscle control (describe known signs and eytpnna). Used whan referring to on effect on an organ or tissue where the size has decreased fren the noraal size. Atrophy con be attributed to heriditary factors, secondary to a diaaeaa process, or duo to a chanical action. (11 LAY LANGUAGE DESCRIPTION: Shrinkage The toMperature at tiiich a Material will ignite spontaneously or bum. (1] The buildne of a chosical in plants and antoala to levels above what is found in its surroundings. (1] SiochoMical Oxygon Dsosnd. An a^irical bioessay type test that Measures the dissolved oxygon conotwd by Microbial life itfiile ooslailsting and oxidizing the organic Matter present In organic waste discharges. It allows eolculsting the effect s* 09 09 0 TERM Boiling point Brenehttis Bulk density Burning rot* C CC CAA Csrcinogsn CardieCardiovaacuiar CAS Muter Cauatic Calling Vatua 0CMN1TI0M USDS GLOSSARY (Continued) B B /S [F TT Page 4 of the dlschargaa on tha oxygen resources of the rteaiving water. (7] The temperature at Wlch a liquid boceama a vapor. Mixtures will not have a distinct boiling point, on tha MSDS indicate either tha initial boiling point or the boiling range. CD Inflaanation of tha larger air paeaeoit of tha tings. It may be caused by disease or physical or chemical Irritants. Systems are generally that of a chest cold and nay include in addition chest pain and coughing. [1] LAY LANGUAGE DESCRIPTION: Inflmmmtion of lungs Mass of powdered or granulated solid Material par wit of voluee. 121 Tha time it take a smwle of solid Material to bum a prescribed distance. The raautta are given in wits of diatanea/tiaa. (1] Degree Celsius or Centigrade, a wit of temperature, using these scales, water bolls at 100*c and freeses at 0*e. CD Closed ew* Eneowtered in flash point naeeuransnts and indicates a test procedure using s closed op. CD Clean Air Act (CAA) regulates sir pollutants. Environmental Protection Agency. CD It fa acbrinisterod by U.S. A material that causes caneer. A chemleal is considered to be a carcinogen, by OEM regulation, if: (a) It has bean evaluated by tha International Agency for Research on Cancer (MIC), and fewd to bo a carcinogen or potential carcinogen; or (b) It is listed os s carcinogen or potential carcinogan in tha Annual Report on Carcinogens pWHahod by the Notional Toxicology Program (NTP) (latest edition); or, <c> It fa regulated by GNU aa a carcinogen; or, (d) Thoro to valid scientific evidence in man or animals dwonatrating a cancer causing potential. (1) A prefix that refers to the heart. Ill A term indicating the heart and Mead vessels. CD Tha Chemical Abstracts Service (CAS) Registry hiafter la a raater assigned by tha Aaeriean Chemical Society's Chemical Abstracts service. It identified a specific chwical sitetones. This meter fa vary useful in searching for information, particularly Wars vsrious chsmical namss and descriptions may be used. CD Sea Alkali. Tha msximui alienable hwon exposure limit for an airborne attetanca which is net to bt exetedad avan momentarily. Also sea PEL and TLV. C2J VVV 000010910 TERM DEFINITION MSOS GLOSSARY (Continued) Page 5 Central Nervous System CERCLA CFR Chemical Family Chemical Chemical Manufacturer [4] Chemical name CHEMTREC Chronic health effact Clestogenic The brain and spinal cord which control the activity of the entire System (CMS) nervous system. Roth sensory and motor impulses. Cl) Comprehensive Envirenmsntel Reeponee, Ccmpenestion, and Liability Act of 1980. The Act requires that the Coast Guard National Response center be notified in the event of a hsxardous subetanee release. The Aet also provides for e fund (the Siperfuid) to be used for the cleanup of abandoned hazardous waste disposal sitas. (1) Uni tad States Cods of Fedsral Regulations (CFR). It is a p^licaton of the regulations that have been promuigetad tnder United States Law. Tha CFR is dividad into Titlas. Tha following titlae may ba useful tdien following this guideline: Title 29 Contains OSHA Hazard Co--mnication standard and other OSHA regulations Title 40 * Contains Enviranasntal Protection Agency regulations, including TSCA Title 49 Contains Department of Trsneporation (DOT) regulations Changes to the regulations are published in the Federal Register. These publications ean ba ordarad through the US Government Printing Office. CD A grot? of stAetaneee that have a ehamical similarity. Ex--pie: acetone, methyl ethyl ketone (NEK), and mathyl isobutyl katona (Milk) are the "Ketone" family; acrolein, furfural, and acetaldehyde ar# of the "aldehyde" family. CD OSHA dafinat a ehamieal as any elaaant, ehamieal cospoutd or mixture of elements and/or c--moulds. C6] An aapleytr with a workplace where chamieal(s) ere produced for use or distribution. The scientific designation of e chemical In accordance with tha nomenclature system developed by the International Union of Pure and Applied Chemistry (1UPAC) or the Chemical Abstracts Service (CM) rules of nomenclature, or a name which will clearly identify the chemical for the purpose of conducting e hazard evaluation. (6) Chemical Transportation Emergency Canter ie a national center established by the Otamical Narmifacturers Association (CNA) to relay pertinent --mrgoncy information concerning specific chemicals on recgieats from individuals. CHEMTREC has a 24-hour toll-free telephone ruber (800-424-9300) to help respond to chemical transportation emergencies for companies Mho have resisted with thorn for this service, tl] An adverse health effect may describe a health affect that occurs after a long-term exposure or a health effect that persists over e long-time or reeura frequently as a result of axpoaura(a). (1) LAY LANGUAGE DESCRIPTION: Delayed health effect or long term health affect. Giving rite to or Inducing dictation or breakages, aa of chromosomes. [81 LAY LAMGUAGE DESCRIPTION: Causae damage to genetic material VVV 000010911 TERM DEFINITION MSO$ GLOSSARY (Continued) Page 6 Closed system System (Equipment or apparatus) designed and used to so that there is no release of the chemicals from the into the surroundings. Closed systems are indicated as a swans to control exposures to hazardous materials or to conditions which would pose a physical hazard. Ctl COD Chemical Oxygen Demand. The amount of oxygen required under specified teat conditions for the oxidation of waterborne organic and inorganic matter. [71 Ceabustible liquid -OSHA Any liquid having a flashpoint at or above 100*F (37.8*0, but below 200*F (93.3*0. except any mixture having ccagwnants with flashpoints of 200*F <93.3*0, or higher, the total voluae of which make ip 99 percent or more of the total voluae of the mixture. Ml -DOT A combustible liquid is defined as any liquid that does not meet the definition of any other DOT classification and has a flash point at or above tOO*F (37.8*0 and below 200*F (93.3*0 except any mixture having one coaponant or more with a flash point at 200*F (93.3*0 or higher, that makes at least 99 percent of the total voluae of the mixture. (91 Common name Any designation or identification such as coda name, coda matoer, trade name, brand name or generic name used to identify a chemical other than by its chemical name; e.g., the comaen name for dimethyl ketone is acetone. (6) Covenant A constituent part; Ingredient. Dl Cempreteed gee -OSHA (i) A gas or mixture of gases having, in a container, an absolute pressure exceeding 40pei at 70*F <21.1*0; or (if) A gas or mixture of gases having, in a container, an absolute pressure exceeding IMpai at 130*F <54.4*0 regardless of the pressure at 70*F (21.1*0; or (HI) A liquid having a vapor praaaura exceeding 4Qpei at 100*F (37.8*0 as determined by Atm D-3Z3-72. (61 -DOT The tern compressed gas" designates any material or mixture having in the container an absolute praaaura exceeding 40pei at 7D*F or, regardless of the pressure sc 70*F, having an absolute prtesurs exceeding 104pei et 130*F; or any liquid flaanmbte material having a vmsr praaaura exceeding 40pef absolute at 100*F as determined by Atm Test 0-323. (91 Compressed gas in solution DOT defines ss a norr-1 iquifled compressed gas idiicb is dissolve in e solvent. [91 Conjunctivitis Inflamotion of the lining of the eyelid and covering of aye. [11 LAY LANGUAGE DESCRIPTION: Eye Irritation VVV 000010912 4,0 TERM DEFINITION USDS GLOSSARY (Continued) Pago 7 Consuner coamodity DOT defines as Ma Materiel that is packaged and distributed in a fona intended or suitable for sale through retail sales agencies or instrumentalities for conaimption by individuals fdr purposes of personal care or household use. This term also includes drug and Medicines." [9] Container OSHA defines as any beg, barrel, bottle, box, can, cylinder, drua, reaction vessel, storage tank, or the like that contains a hazardous chanical. Pipes and piping systaMB, and engines, fuel tanks or other operating systsMB in a vehicle, are not considered to be containers. (61 Comas The transparent part of the eye which costs the iris and pupil. Eye irritation studies grade the degree of domes seen in the comes and the tine until coaptata recovery as an endpoint U3 Corrosive Material -OSHA A chanical that causes visible destruction of, or irreversible alterations in, living tissue by chanical action at the site of contact. For exanpla, a chanical is considered to be corrosive if, Wien tested on the intact skin of albino rabbits by the Method described by the DOT in Appendix A of 49 CFR Part 173, it destroys or changes irreversible the structure of the tissue at the site of contact following an exposure period of 4 hours. This tors shall not refer to action on inanimate surfaces. (6] -DOT A corrosive Material Is a liquid or solid that causes visible destruction or irreversible alterations in htmen skin tissue at the site of contact, or in the case of leakage iron Its packaging, a liquid that haa severe corrosion rate on steel. (a) A notarial Is considered to be destructive or to cause irreversible alteration in Inman skin tissue if when tested on the intact skin of the albino rabbit by the technique described by DOT, the structure of the tissue et the site of contact is destroyed or changed irreversible after an expoeure period of 4 hours or less. <b> A liquid is considered to have a severe corrosion rate If its corrosion rate exceeds P.290 inch per yaer (1PY) on steel (SAE 1020) at a test tasperatire of 130*F. An acceptable test is described in KACE stenderd TW-01-69. (c) Ntamn experience or ether dite tehee precedence ever aniaal experiaanta. (91 Cryogenic liquid Cutaneous DOT daflnaa aa a rafrigaratad liquaflad gae having a boiling point coldor than *130*F (90*0 at ana afoa^iara, abaoluta. (9] Ralated to tha skin. laa daraal. (23 LAY LAhCUAGE DESCRIPTION: Of tha Skin CWA Clean Hater Act. Federal leu enacted to regulate water pollutants. CUA is aAHni stored by ERA. <99> Cyanosis A condition Wiere the observable vascular body parts bacons bluish (e.g., nei lbeds, lips, end skin) The condition Is caused by s lower oxygen in the blood hnaoglebin (e.g., in venom bleed). Chemical such as carbon Monoxide can reduce hmaoglobin function, til LAY LANGUAGE DESCRIPTION: Slue skin and nails my 000010913 TERM DEFINITION MSOS GLOSSARY (Continued) Page 6 0 Dangerously reactive chemical A chemical that is able to wdergo a violent aelf-aceelarating exothermic chemical reaction with camion materials, or by itself. (31 Decomposition Breakdown of a materiel or s^etsnee (by heat, chemical reaction, electrolysis, decay, or other processes) into parts or elemsnts or siller empouds. C2) LAY LANGUAGE DESCRIPTION: Breakdown Delayed hazard The potential to cause an adverse effect diieh may not appear until a long period of tine. Carcinogenicity, teratogenicity and certain target organ/aysten effects are examples of delayed hazards. C3] Density The ness (weight) per wit voluee of a eubstanee. For exmqaLe, lead is *h aore dense than alusirum. 12] Dermal Relating to the skin. [2] LAY LANGUAGE DESCRIPTION: Skin Dermatitis Inflammation or irritation of the skin. Sy^tone of dermatitis are rash, itching, blisters and crustiness. (1] LAY LANGUAGE DESCRIPTION: Skin irritation or rash OOT Department of Transportation. Hiedguarterad In Ueahington, DC, it is the Agency of the Federal ftrivarrmanr that polishes regulations pertaining to the transport of hessrdous materiel sin *D CFR. (10) Dysplasia Malformation; ^normal development of an organ or tissue [1] Dyspnea Difficulty in breathing; labored breathing or ehortneee of breath. II] LAY LANGUAGE DESCRIPTION: Shortneea of breath ECgO 1C Effective Concentration. A calculated value, derived experimentally, which represents e concentration which would effect to 50 of the tooted population. [1] EOjO ED Effective dose. The calculated daee, derived experimentally, which would produce a specified effect in SO percent of the teat population IT] Edema Swelling tissues or eolle in which abnormally large amounts of fluid collect in intercellular spaces. Cl] LAY LANGUAGE DESCRIPTION: Swelling EDI Electronic Date Interchange. Efforts have been mderwey to develop a standard for the transmission format for USDS within the context of an EDI environment. CIO] t,Z VVV QOOOIO^14 TERN DEFINITION MSOS GLOSSARY (Continued) Pag# 9 EEC EINECS Ea0iyse-- Eflployer ERA Epid--iology Epistaxia Eryths-- Excessive Explosive osna -DOT European Seen--ie Co--unity. European Inventory of Existing Ch--leal Sifcatances. SiMilar to the TSCA inventory. Contains all aubataneet Marketed to 1982 in the European Coeaunity. Any substance, not in EINECS, is subject to pre--rfceting notification to the appropriate authorities. (10) A condition of the Imps in which it beeoats difficult to exhale this nay be due to aucue plugging passage ways. (1) OSNA defines as a person engaged in a business where eh--icals are either used, distributed, or are produced for use or distribution, including a contractor or siiicontractor. (6) U.S. Enviro--sntsl Protection Agency. An Agency regulatory end onforewssnt authority on environ--ntal --tters. A--inistars FtfRA, CUA, CAA, RCXA, TSCA end other enviimantelly related Acts. C2l Scisnee concsrned with the study of disooeo in e gsntrol population. Detenrination of the ineidsnea (rata of occurrence) and distribution of a particular disease (as by ago, sax, or accretion) which --y provide infer--tion about the causa of the diaaaae. m LAV LANGUAGE DESCRIPTION: Study of disease origin Nosebleed, h--rrhsgs fr-- the no--. (11) LAV LANGUAGE OESCNIPTION: Nosebleed fleefewaa of the akin due to congaation of the capillaries. (11) LAY LANGUAGE DESCRIPTION: RahMl rash Exceeding the usual, proper, or nor--l. As distinguished fr-- words such as 1--oderate and Inordinate, excessive lilies an a--unt or degr-- too great to be reasonable or acceptable. (9) A chadleal that causes a sudden, el--at instantaneous release of pressure, gas, and h--t whan sheeted to sudden shock, pressure, or high t--perature. (6) An explosive is defined -- any eh--leal cea--xnd, Mixture, or device, the pri--ry or earn purpees of tdileh is to function by explosion, i.e., with si*tantielly instantaneous release of gas end heat, unless such cc--ond, Mixture, or device is otherwise specifically classified by DOT. (9) Expletive Units The range of concentration of a fls--able gas or vapor (X by volt-- in oir) in which explosion can occur i^en ignition in e confined area. (4] The boundary-11 no Mixtures of vapor or gas with air, which, if ignited will just 000010915 TERM DEFINITION USDS GLOSSARY (Continued) PGC 10 Exposure Extremely flnaaabte liquid Extremely hazardous sdxtanct (SARA) f Firet Aid Flaamnble aerosol propagate the flame. They are known as the "lower and upper or explosive limits," and are usually expressed in terms of percentage by voluee of gas or vapor in air. (12] \ OSHA defines as, "`exposure; or `exposed1 naans that an employee is subjected to a hazardous eheniea! in the course of nqoloymsnt through any route of entry (inhaletion, ingestion, skin contact or absorption, ate.) and includes potential (e.g. accidental or possible) exposure." [6] Any liquid having a flash point below 20*F ('6.7*0, unless the liquid is a mixture having consonants that constitute 99 percent or more of the liquid by volimm and that have flash points of 20*F or greater. (3) A eiAstanee listed under Section 302 of SARA Title III with certain reporting and emergency planning requirements. (1) Degree Fahrenheit, a wit for measuring temperature. On the Fahrenheit scale, water boils at 212*F ad freezes at 32*F. (2) Imaadiate mesaurea that eon be taken by the victim or others persons in case of contact or exposure to a notarial, ineluding ending the exposure and using materials generally available to reduee or eliminate adverse health effects. [1] An aerosol that, when tested by the method described in 16 CFR 1500.AS, yields a flame projection exceeding 18 inches at full valve opening, or a flashback <a flame extending beet to the valve) at any degree of valve opening. 16] VVV 000010916 TERN DEFINITION NSOS GLOSSARY (Continue) Page 11 FlMMbi* co^ressed gu DOT defines m any ccwpressed ga* If any of th following occur*: (1) Either a mixture of 13 percent or laaa (by voluaa) with air forma a flanmable aixture or tho flammable rang# with air is wider than 12 parcant ragardless of tha lowsr Halt. Thaoa limits shall ba determined at staospharic tsaparatura and pratsure. (2) Using tha Suraau of Explooivas1 Float Projact ion Apparatus, tha float projects aora than IS inches beyond tha ignition source with valve opened fully, or, the flaae fleshes beck and bums at tho valve with any degree of valve opening. (3) Using the bureau of Explosives' Open Ones Apparatus there is any significant propagation of float away froa the ignition source. (4) Using the lureeu of Explosives1 Closed Drue Apparatus there is any explosion of the vapor-air aixture in the drus. t9) Flaweble gas PlaMMble liquid -OOT -OSHA (A) A gas, that at aafeient tsaparatura and pressure, fores a f tamable aixture with air at t concentration of thirteen (13) percent by volute or less; or (!) A gas that, st aafeient te^arature and pressure, fores a range of flaHHble aixturee with sir wider than twelve (13) parcant by voltae, regardless of the lower Itait. C61 OSHA Liquid, f tenable mans any liquid having a flashpoint below 100*F (37.8*0 except any aixture having with flashpoints of 100*F (37.8*0 or higher, the total of which aeke tp 99 poreant or aora of the total voluaa of tho alxturo. (6) A f tenable liquid aeons any tiqild having a flash point below 100*F (37.8*0, with tha following axcspeionai a) Any liqiid noting tha definition of a coaprsssod gas; b) Any aixtura having one g"H****--** or aore with a flash point of 100*F, (37.8*0 or higher, that aekee ip at least 99 percent of the total veins of the aixture; A distilled spirit of 140 proof or lower is constderod to hove a flesh point no lower than 73*F. [9] Flaaaeble range The term finable range designates the difference between the ainfan and maximuir volne parcantages of tho notorial in air that foras a flsnabla ccepreased gas. 19] -OSHA A aolld, other than a Moating agent or axploaive that is liable to cause fire through friction, absorption of moisture, spontaneous chaaieal change, or retained hoot froa mrfaeturing or processing, or idiich ean bo ignited readily and when ignited bums oo vigorously and persistantly as to create a serious hazard. A chaaieal shall bo considered to be e flaneble solid, if when tooted by tho aethod described in 16 CFR 1500.44, It ignites end bums with s self-sustained flans st a rate greater than one- tenth of an inch per second along its major axis. 16] -DOT Any solid mstori si, other than an explosive, which, under conditions normally incident to transportation is liable to csum fires throu* friction, retained hoot from aarmifacturlng or processing, or trfiich can be ignited readily and whan ignited bums so vigorously and persistently os to create s serious transportation hazard, included in this class are spontaneously combustible and water-reactive materials. [9] VVV 000010917 TEftM DEFINITION MSOS GLOSSARY (Continuod) Pag* 12 ra !^ ca a i! Flash point -OSKA Tha minlaua eaaperature at which a liquid givas off a vapor in sufficient concentration to -ignita whan tasted as follows: (i) Taglfabua Closed Taster (See American National Standard Method of Test for Flash Point by Tag Closed Tester, 111.24*1979 (ASTM 056*79) for liquids with a viseosity of less than 45 Saybolt University Seconds (SUS) at 100*F (37.6*0, that do not contain suspended solids and do not have a tendency to fons a surface film uider test; or (ii) PenakyHarterm Closed Tester (See American National Standard Method of Test for Flash Point by PanakyMartana Closed Tester, 211.7*1979 (ASTM D93-79) for liquids with a fiacosity equal to or greater than 45 SUS at 100*F (37.8*0, or that contain suspended solids, or that have a tendency to fora a surface film under test; or (f ID Setaflaah Closed Tester (see Acerlean National Standard Method of Test for flash Point by Setaflaah Closed Tester (ASTMD 3278*78) Organic peroxides, which undergo autoaccalerating theraal decomposition, are excluded from any of the flashpoint deteneinacion Methods specified above. 6) -DOT The minimus Coloratura at which a liquid gives off vapor within a test vessel in sufficient concentration to fora an ignitable Mixture with air near the surface of the liquid. DOT prescribes certain test methods. 19] Foraaeable arargancy Any potential occurrence such as, but no limited to, equipment failure, rt^ture of containers, or failure of control equipment idiich could result in an uncontrolled release of a hazardous chemical into the workplace. 6] Freezing point See netting point. Smoke or vapor with solid particles. Often with metals chemical reactions or heating (as in welding) will produce volatilized metals diich nay lead to an series of occupational Illness termed raatal fiat fever*. CT] Gavage Forced feeding, especially throoh a tube passed into the stomach. 11] Gastric lavage Medical procedure involving irrigation or washing out of the atorach. 1] Gastatlen The develepennt of tha fetus in the uterus from conception to birth; pregnancy. 2] LAY LANGUAGE DftCSIPTIOM: Prepmncy Hazard CoHmaticatlen Standard Hazardous . The Hazard Coanication Standard is an OSHA regulation issued wider 29 CFN pert 1910.1200. It details the requirements of NBSs and labeling. 1] The term hazardous is used by many federal and state agencies to describe substances subject to laws and regulations. Soma examples are given below. OSHA DOT A "hazardous chemical* is any chemical which is a physical hazard or e health hazard according to OSHA Hazard Coaaunieation Standard Criteria. DOT describee a "hazardous material* aa a siAstanca er rattrial whieh has baen determined by the Secretary of Transportation to bo capable of posing an wireaaonabla risk to health, safety, and property when transported In commerce, end whieh has been so designated. yVV 00001091 TERM OEFtNITlON IISOS GLOSSARY (Continued) Page 13 A Material, including its ixturos and solutions, that (1) Is listed in ,th* Appendix to the DOT Hazardous Materials Table; (2) Is in a quantity, in one paefcegs, which equals or exceeds the reportable quantity (HQ) listed In the Appendix to the hazardous Materials Table; and (3) When in a Mixture or solution, is in e concentration by weight which equals or exceeds the concentration corresponding to the RQ of the Material, as shown in the following tablet RQ pomde (kilograas) wsight Concentration by Percent ppm 5000 (2270) 1000 (4S4) 100 (45.4) 10 (4.54) 1 (0.454) 10 2 0.2 0.02 0.002 100,000 20,000 2,000 200 20 CERCLA ICXA A "hazardous stAatance" is any substance designated under section 311(b)(4) of the Clean Water Act; section 307(a) of the Cleon Water Act; section 112 of the Cleon Air Aet and any RCRA hazardous waste. Each of these sifeotsnees is assigned a "reportable quantity" or RQ. (9) RCRA describes a HaxardoM waste" as any discarded Material that Is regulated wider RCRA it exhibits the characteristic of ignitabillty, corrosivity, reactivity or iP toxicity as described therein or because it is listed. Hazard Homing Defined by QSMA aa any words, pictures, syafcols, or coatoinetion thereof appearing on a label or other appropriate fans of warning which convey the hazard(s) of the eheaieal(s) in the eentainer(e). W Health hazard A cheatcal for which there la statistically significant evidence based on at least one study conducted In accordance with established scientific principles that acute or chronic health effect way occur in exposed alloys**. The tern "health hazard" includes ehanicsls tdtieh are carcinogens, toxic or highly toxic agents, reproductive toxins. Irritants, corrosives, sensitizers, hepetotoxlm, nephrotoxine, neurotoxin*, agents which act on the hawetopoietic syetaa, and agents which dawege the lunge, akin, eyee, or mucous aaabrane*. (A] Mopato Hepstotoxin* Prefix Meaning liver. (1) Chonlcals which product liver rtoaeg*. [61 LAY LANGUAGE DESCRIPTION: Liver toxins Highly toxic chsaical OSMA defines at follows: A chOMicel falling within any of the following cetegorioe: (a) A chenicel that has a Median lethal dose (LDcQ) of SO nlUigrs or less psr kilogran of body weight when adrinisttred orally to albino rats weighing between 200 and 300 grans each (b) A chsnical that has Median lethal does <U>S0) of ZOO allMgraaw or lose par kilograa of body weight whan adainistared by continuous contact for 24 hours (or loss, if dssth occurs within 24 hours) with the bare skin of albino rabbits weighing between 2 and 3 kilograas eaeh VVV 000010919 TERM DEFINITION USDS GLOSSARY (Continued) Page U (e) A chanicat that has a Medial lathal coneantration (LC^O) of gas or vapor in air of 200 parts par Million (ppaO or lass by voluaa, or 2 Milligram per liter or less of Mist, fuse, or dust, when aotainistered by continuous inhalation'for 1 hour (or less, if death occurs within 1 hour) to albino rats weighing between 200 and 300 gram each. 16] HMIS I ARC Hazardous Material Informtion Systaa. A system, developed by the National Paint and Coatings Association, dasipied to infona workers of the hazards of the chemicals they use and of mans of protacting themelves frae those hazards. It uses a nuaerical rating to indicate the level of hazard, with 6 being the highest and 0 the lowest. It addresses acute health, flamability and reactivity hazards. CIS] international Agency for Research on Cancer. Cd^SCjUilX- p/ icso A calculated statistical value whereby a concentration causes inhibition of an effect, behavior, or biological action to SOX of the treated subjects or eniaals. Identity ignition tanperatura Any chenical or eomon nam which is indicated on the Material safety data sheet (MBS) for the chMsical. The identity uaed shall penait cross-references to be node waonq the required list of hazardous chemicals, the label and the HSDS. ([63 The MiniMun tanperature required to initiate or cause self-sustained coabustion in any substance in the cbesnca of a sperfc or flam. (4] Imndiata hazard A hazard with iomdiate effect(s). See acute health effects. C23 lapervioua laportar A Material that dees not alien another siAetence to pass through or penetrate it. C23 The first business with alloysas within the Custom Territory of the Uiited States which receives hezerdoue chmlcsla produced in other cotntrits for the purpose of supplying thm to distributors or alloysrs within the United States. (61 Incospetible Materials that eould cause dangerous reactions by direct contact with one another. C21 Inflsanable A synonym of flamable. Ingestion Inhalation Inhalation hazard - DOT Taking in by the Mouth. Z3 LAY LANGUAGE DESCRIPTIONS Seallowing resthing In of s siAstance in the fore of o gas, vapor, fuse, Mist, or dust. C21 LAT LANCUA8E DESCRIPTION: Drasthing A chmiesi that is a liquid having a saturated vapor concentration <ppM) at 68*F (20*0 equal to or greeter than tan tines Its LC-0 (vapor) value (ppm), if the LC^O value is 1000 parts par Million (ipa) or lose whan adninistsrad by continuous inhalation for 1 hour (or lose, if death secure within 1 hour) to albino rats weighing between 200 and 300 gram each, provided such concentration, or condition, or both, are likely to be encountered by nan whan the ehenical it used in any reasonable forsaaabla Mannar. [9] VVV 000010920 TERM DEFINITION ttSDS GLOSSARY (Continued) 15 Intubation in vivo in vitro l.P. Iriti* Irritant Irritating material Irritation I.V. Jauidic* Lay tanguaga LEI or LFL LEL The adrtnistration of a teat doae through a tube inserted into the note, throat, or larynx. C1J Experiments in live aniaels. [1] Experiments with eel la or tissues from organises conducted outside of the organise. (99) Intraperltoneally. A route of adsinistration of a material In which the material is injected in to the pertloneal (abdominal/pelvic) cavity. 11] Inflammation of the iris, the circular pigmented m--brans behind the cornea, perforated by the pi^il. till LAY LANGUAGE DESCRIPTION: Eye irritation A chemical, which Is not corrosive, that causae a reversible inflammatory offset on living tissue toy chemical action at the site of contact. A chemical is a skin irritant if, when tasted on the intaet skin of albino rabbits by the methods of 16 CFR 1500.41 for 4 hours exposure or toy other appropriate techniques, It results in an sapirical score of 5 or more. A chemical is an eye irritant if so determined wider the procedure liatad in 16 CFR 1500.42 or other appropriate techniqjes. [6] DOT defines an irritating material as a liquid or aolid atbatance which teen contact with fire or whan axpaaad to air givas off dangerous or intensely irritating fuses, such aa brabanzylcyanide, chloracetophenone, diphanylamineehlorarsine, and diphenylchlorarsine, tout not including any poisonous material. Class A. [9] A condition of irritability, soreness, roughness or inflaamtion of a bodily part. C51 Injection into a vein. Not g canon route of occupational exposure. Cl] A symptom of Uver damage, characterized by yellow appearance of the akin and ayes. Ill LAY LANGUAGE DESCRIPTION: Yellowish akin Language that can be understood by the public at large. Cl] Lower explosive limit, or lower flamabte limit, of a vapor or gas; the lowest concentration (lowest percentage of the substance in air) that will produce a flash of fire when an ignition source (heat, ore, or flame) is present. At concentrations lower than the LEL, the mixture it tee "lean11 to bum. Also sea "UEl". C23 Whan speaking of toxicity data LEL * lowaat affect level, it is the lowest dose used in s toot which produced toxle affects. CIS] VVV 000010921 TERM DEFINITION USDS GLOSSARY (Continued) Pagt 16 10,0 The calculated concentration of e aiettrial in air that is expected to kill 40 percent of a grot*} of teat anlaele with a single exposure (usually 1 to 4 hours). The LC^O is expressed as parts of Material per Million parts of air, by voluse (ppm) for gaees and vapors, or as MlUigrane of aattfial per liter of air (og/l) or Milligrams of Material per cubic meter of air (ag/sr) for dusts and mists, as well as for gases end vapors. (23 LCLq Lethal Concentration Low - the lowest concentration of a siPatanee in air, other than LCjQ, which has been reported to have caused death in humane or animals. The reported concentrations may be entered for periods of exposure which ere less thsn 24 hours (acute) or groator than 24 hours (siAaeute end chronic). LOjO A single calculated dose of a material expected to kill 50 percent of a group of test animals. L00 dose is usually expreseed as milligrams or grama of material par kilogrw of animal body weight (mg/kg or g/kg). The material may be adainistered by mouth or applied to the skin. (23 L0L0 Lethal Does Low - the lowest does (other than L0$0> of a siPetanct introduced by an route, other than inhalation, over any given period of time in one or more divided portions and reported to have caused death in hiemna or animals. (2) Lacrimation Secretion end discharge of tears. (21 leerimator A materiel which causae tearing In the eyes either from direct contact or vapors. [1] LAY LANGUAGE DESCRIPTION: chemical causing tearing Uttorgy The condition of drowsiness, tlrecDmes, or indifference. (113 LAY LAMflUAgf DESCRIPTION: fatigue or slowness, tiredness liquified eo^reesed DOT describes as a gas tfilch, under the charged pressure, is partially liquid at a tm^erature of 7D*F. 191 Malaiaa A feeling of general discomfort, distress or wwaeineea, an out-of-sorts fooling. (2) LAY LAMQUAGE DESCRIPTION: flu-like Material Materiel Safety Date Sheet (MSD8) Written or printed materiel concerning e hazardous chemical which is prepared in eceordwice with OSMA regulations in 29 CFR 1910.1200. [6] Melting point The melting point or frooting point of a pure siimtanca is the tesperature at *ich its crystals ere in equilibria with the liquid phase at atmospheric pressure. The term `melting point* la used tdien the ecpiUlbriui tesperature is approached by heating the solid. Tho terms melting point and freezing point ere often used interchangeably, depending on idiether the substance is being heated or cooled. (4] 000010922 WVV TERM DEFINITION MSOS GLOSSARY (Continued) Pag* 17 Hist M IT I Molecular formula Molecular Might Nut*Qfl NarcMii Narcotic Niuin NCI Nocrotit NooplMio Nephrotoxin Neuritis Neural Liquid droplets suspended in air generated by condensation fro* the gaseous to the liquid state or by breaking up a liquid into a dispersed state of splashing, foaming, atomizing, or the like. [3] Japanese Ministry international Trade t Industry. A chemical inventory system. (1] A written representation, using sysfeols, of a chemical entity. It shorn the actual rxmbar and kind of atoms in a molecule. 14] Weight (mass) of a moleeule baaed on the sub of the atomic Mights of the atoms that make up the molecule. [2] A stAstance or agent capable of altering the genetic material in a living cell. [2] LAY LANGUAGE DESCRIPTION: may damage genetic material A state of shper, unconsciousness, or arrested activity produced by the influence of narcotics or other chemicals. C23 An material that produces nacrcoais. Cl] Tendency to vomit, feeling of sickness at the stomach. [23 National Chemical Institute is that part of the National Institutes of Health that studies cancer causes and prevention as Mil as diagnosis, treatment, and rehabilitation of cancer patients. U1 Death of tisaue. Corrosive chemical may cause localized necrosis at site of contact whleh will lead to permanent demoge and scarring. (1] LAY LANGUAGE DESCRIPTION: tissue destruction A condition characterised by the presence of new growths (tusors). fZl LAY LANGUAGE DESCRIPTION: timer A material that may cause effects and potential injury to the kideys. [1] LAY LANGUAGE DESCRIPTION: ki*wy toxin Inflammation of a nerve. [11] Describing a nerve or the nervous system [1] WV 000010923 MSDS GLOSSARY {Continued) 0 B a IF TT Psgo 16 TERM DEFINITION Neurotoxin Neutralize NFPA NrOSK HIM NOEL Non-liquified CLfll MMd QM me HTP Odor threshold Orel Organic peroxide A notarial that effect* the nerve cells end eey produce anotionel or bshevioral abnormalitias. (21 LAY LANGUAGE DESCRIPTION: eeuee effects on nervous sy*te To eliminate potential hazards by inactivating strong acids, caustics, end oxidixers. For exalte, acids can be neutralized by adding an appropriate amount of caustic si*stanca to the spilt. (21 National Fire Protection Association is an intametional maabership organization which promotes/ioproves fire protection and prevention and establishes safeguards against loss of life and property by fire, test known on the industrial scene for the National Fire Codas 16 volume of codes, standards, raco--nrtad practices and manuals developed (and periodically ipdeted) by NFPA technical coanittees. Among these is NFPA 704N, the code for showing hazards of material as they night be encountered trter fire or related emergency conditions, using the familiar diamond shaped label or placard with appropriate numbers or symbols. (21 National Institute for Occwatienol Safety end Health, U.S. Pi*lic Health Service. U.S. Department of Health and Hiaan Services (OHHS), amount other activities, tests and certifies respiratory protective devices and air saspling detector tites, rarnsannrta ocelotIonal exposure limits for various sitetaneee, and assists OSHA and MSMA in eect^etionol safety and health Investigations and research. (21 National Library of Modlcina. No observed offset level - The highest dose of a substsnee used in a test whieh produces no observed adverse effects. (11 DOT describes sa a gas, other than gas in solution, which mder the charged pressure is entirely gaeeoua at a tasperatura of 7Q*f. (91 National Response Canter is a notification center that must be called when significant oil or chemical spills or other environment-related accidents occur. The toll free telephone nM*r is 1-600-424-8802. C23 ST Notional Toxicology Program. The NTP publishes Identifies substances thet hove been studio^ or humn evsluaticne. (21 (L Report on Corcirwoens which carcinogens,Mn animal J W, apfcteU*T> The lowest concentration of o substance1* vapor. In air, thet can be smelled. (21 Used in or token into the body through the mouth. (21 An organic eomound that contain* tha bivalant -0-0- structure and which may be considered to be e structural derivative of hydrogen peroxide where one or both of the hydrogen atoms has bean replaced by an organic radical. (6,91 VVV 000010924 DIMif TT TERM OEFIHITIOM MSOS GLOSSARY (Continued) Page 19 ORM-A (DOT) An ORM*A material ia a material which has an anesthetic, irritating, noxious, toxic, or other similar .property and tiiich can cauae extreme annoyance or discomfort to passenger and ereW In the even of leakage during transportation. [9] ORM-B (DOT) ORM-C (DOT) An ORM-B material is a material (including a solid whan wet with water) capable of causing significant damage to a transport vehicle from leakage during transportation. Materials meeting one or both of the following criteria are ORM-B materials: 1. A liquid substance that has a corrosion rate exceeding 0.250 inch per year (1PY) on aluairaa (nonclad 7075-T6) at a test temperature of 130*F. An acceptable test is described in RACE Standard TM-01-69. 2. Specifically designated by name in the hazardous Materials Table; <49 cfr 172.101). tn An orn-C material is a material which has other inherent characteristics not described as an ORM-A or ORM-B but which make It muitable for shipment, unless properly identified and prepared for transportation. Each ORM-C material is specifically named in the hazardous Materials Table (49 CFR 172.101) (9) ORM-D (DOT) An ORM-D material is a material such aa a conaiamr coaamdity which though otherwise stject to the DOT regulations, presents a limited hazard during transportation due to its form, quantity and packaging. (9] ORM-E (DOT) OS Oxidizer An ORM-E is a material that is not Inclined In any other hazard elaas, but it subject to transportation regulations. Materials in this class inelude: 1 hazardous wasta. 2 Hazardous substances. (9] Occupational Safety and Health Administration, u.S. Department of labor regulates workplace conditions. [1] -OSHA "Oxidizer* means a chemical other than a blasting agent or explosive as defined in 11910.109 (1) by OSMA, that initiates or promotes cofeuetion n other materials, thereby eaueing fire either of Itself or through the release of oxygon or other gases. (61 -DOT An oxidizer Is a si*otones such as a chlorate, pramanganete, inorganic peroxide, or a nitrate, that yields oxygan readily to stimulate the combustion of organic matter. (93 PEL Permissible Exposure Limit is an occupations exposure limit established by OSHA's regulatory authority, it may be a time-weighted average (TUA) concentration or a maxim* concentration never to bo exceeded either instantaneously (CE1LIHG) or during any 15 minuta parlod (STEL). (13 Peneky-Nertene Closed Cl? A mathod for determining flash point. (23 Peripheral neuropathy Ftnetional disturbances and/or pathological changes in ths nerves in the extremities (herds, feet, eras and lags). (13 VVV 000010925 73 TERM DEFINITION MSDS CLOSSAKT (Continued) Page 20 Personal protection pH Physical hazard PnauaCo) P--oconiosis Poison A*DOT Poison 1*007 The act of protecting the body against contact ulth known or anticipated chemical hazards. Equip--ht for this purpose includes respirators, gloves, safety glasses, chemical resistant clothing, etc. (16) The symbol relating the hydrogen ion (H*) concentration of that of a given standard solution. A pH of 7 is neutral. Niafeers increasing from 7 to K indicate greater alkalinity. N--be-- decreasing from 7 to 0 indicate greater acidity. [2] A eh--leal for trfiich there is scientifically valid evidence that it is a coatoustible liquid, a coapressad gas, explosive, fla--able, an organic peroxide, an oxidizer, pyrophoric, --stable (reactive) or water*reactive. 16] word element pertaining to ling, air or gas. Ill] A condition of the lu-- in which there is permanent depoeition of particulate --tter and the tissue reaction to its presence. It may range from relatively harmless forms of Iron oxide depoeition to destructive for-- of silicosis. (23 LAY LANGUAGE DESCRIPTION: de-alts in tunes causing disease Extra--ly dangerous poisons, Clsss A, are poisonous gases or liquids of such nature that a ver a--11 amount of the gaa, or vapor of the liquid, mixod with air it dangoroua to lifo. This elaea includes the following: (1) Iro--catena. (2) Cyanogen. (3) Cyanogen chloride containing loea than 0.9 pare--t water. (4) Diphoegena. (5) Ethyldichloraraine. (6) Hydrocyanic acid <>S%). (7) Methyldichlora--1--. (8) Nitrogen paroxido (tttroxido). (9) Phosg-- (diphoogone). (10) Nitrogen totroxlda-nitrie oxide mixtures containing up to 33.2 percent weight nitric oxide. (4) Claes S poisons are those at*etaneee, liquid or solid (including pastes and s--ieolide), other than Cleee A poise-- or Irritating --teriele, idiich ere k-- to toe so toxic to n-- as to afford e hazard to h--Ith during tra--portati--; or which, in the ahawra of adequate date -- h-- toxicity, are pres--ed to toe toxic to men because they fall within any e-- of the following categories Wen tested -- laboratory --f--le: (1) O--l toxicity. The-- which prortre death within 48 hou-- in half or more than half of a g--ig> of 10 or mo-- whits laboratory rata weighing 200 to 300 grams at a single do-- -- 50 milligra-- or loss par kllogr-- of body weight, when a--ini stared orally. (2) Toxicity -- inhalation. Those which produce death within 48 hours in half or mo-- than half of a grow of 10 or mo-- --its laboratory --to weighing 200 to 300 g--, whan inhaled continue--iy for a period of o-- hour or lose at a concentration of 2 milligra-- or loss per liter of vapor, mist, or dust, provided such concentration is likoly to bo enco--tered by nan when the ch--ical prod--t fa used in any reasonable fo--seatole man--r. (3) Toxicity by skin absorption. Those which produes death within 48 hou-- in half or no-- than half of a group of 10 or mo-- rabbits tested at a dosage of 200 milligra-- or less per kllogr-- body wight, Wen e--ini stared by continuous contact with the bo-- skin for 24 hou-- or less. The fo--goi-- categories shell not apply if the physical characteristics or the VVV 000010926 TERM DEFINITION MSOS GLOSSARY (Continued) Past 21 probable hazard* in hi,awn* aa shown by experience indicate that the sifeetences will not eaime serious sickness or dsath. (4) Poison inhalation-DOT A liquid having a saturated vapor concentration at 20*C <68*F) equal to or greater than ten tides its LC*0 (vapor) value if the LC0 value is 100 parts per Million (ppm) or less. LC^O for this definition is the concentration of vapor that, when adsinistered by continuous inhalation of both asle and fesmle young albino rats for one hour, is most likely to cause death within 14 days to one half of the animals tested. The result is expressed in Milliliters per eifeie aster of air (ppa). If IC*0 data are available based on other than a one hour exposure, a factor nay be lied to determine an acceptable one hour value for the purposes of this section. If the only value available is for a 4 hour exposure, that value is mjltiplied by 2. This method of estimating a IC0 value may net be ueed when a material causes death by direet pulmonary effect, i.e., by destruction of lung tissue as opposed to systemic poisoning. For these corrosive poisons, the exposure period oust be one hour. (4) Polyiar A high molecular weight molecule of repeating units. [1] Polynrlnticn A chemical reaction in which one or more smell molecules cosine to form larger molecules. A hazardous polymerization is such a reaction that takes place at a rate that releases large mams of energy, if hazardous polyswrizetion can occur with a given material, the MOS usually will list conditions that could start the reaction and -- sines the material usually contains a polymerization inhibitor -* the length of time during which the Inhibitor will be effective. (23 Pressure-generating A chemical that falls within any of the following categories: (1) A chemical that generates pressure by spontaneous polymerization uiless protected by the addition of on inhibitor, by refrigeration, or by other thermal control. (2) A chemical that nay dacampaaa to release gas in its container. (3) A chemical that pressurizes the contents of a self-pressurized container. [3] Product name The trade name of the manufacturer; seem cosendity chemicals are sold by their cosewn Pulmonary edma Pyrophoric Pyrolysis RCRA A build up of fluid In lings, til LAT UWOMfiE DESCRIPTION: fluid in the lines A chemical that will ignite spontaneously in air at a temperature of 130*F (S4.4*C) or below. (5) LAY LANGUAGE DESCRIPTION: ianites in air with external heat source Transformation of 0 cospowd into one or more other siAetanees by heat atone, i.e., without oxidation. Though the term implies decomposition into smaller fragments, pyrolytic change nay also involve isomerization and formation of higher molecular weight compounds. 14] Resource Conservation and Recovery Act is environmental legislation aimed at controlling the generation, treating, storage, transportation and disposal of 7S- VVV 000010927 TERM DEFINITION NSOS GLOSSARY (Continued) Pag* 22 Reactive Reactivity Reducing agent Registry mMbtr RQ Residue Respiratory RYECS Routt* of ixppRurt SARA Title III hazardous wastes. It is administered by ERA. (1) See unstable. Chemical reaction with the release of energy, undesirable effects -such as pressure buildup, tw^srature increase, formation of noxious, toxic or corrosive byproduct bay occur because of the reactivity of a uAMtanee to heating, burning, direct contact with other Materials, or other conditions in use or in storage. [23 In a redaction reaction (which always occurs aiaultaneoualy with an oxidation reaction) the reducing agent is the chsaical or stdstanee which <1) costoines with oxygen or (2) loses elsctrons to the reaction. See Oxidation. (21 See CAS mafeer. Reportable quantity. The quantity of a substance designated tnder CERCLA as hazardous the release of which requires notification to the National Response Canter. <500) 4245802. <9> For the purposes of the Departnant of Transportation, reportable quantity Means the quantity specified for a etdetanee in the Appendix to the Hazardous Materials Table. m For the purposes of SARA Title HI, reportable quantity Means, for any carela hazardous stdetMce the reportable quantity established therein for such subetsnee, for any other siAstanca the reportable quantity ie one pend. (9) As e pert of the DOT regulations residue refers to the Material rMsining in s packaging, including e tank car, after its contents have been wtloeded to the Maxima extent practicable and before the packaging is either refilled or cleaned of hazardous Material and purged to resows any hazardous vapors. [91 Pertaining to respiration. Including inspiration and aspiration, diffusion of gaaaa (oxygon and earbon dioxide) free alvoolf to the blood end their transport free the body cells. [11] Registry of Toxic Effects of ChaMical Substances. Pifclishad by N10SH, RTECS it a ecapandiia of the know) toxic and biological effects of cheat cal sifeetances. See NIOSH. (2) The eeene by tftich Material aey gain access to the body, for exaeple, breathing, eating or through the akin or ayes. (11 Title HI of the Stferfwtf toandsants and Reauthorization Act of 1966 also know) as the Eeergency Planning and Coaawilty Rlght-to-Know Act. It requires extensive adaaiasien of InfocSMtion about hazerdaua ehaaicala to EPA, States end local coMMWiftiea and establishes a national prograa of --argancy planning. AAHnisterad by EPA. VVV 000010928 TERM DEFINITION was GLOSSARY (Continued) Peg* 23 Saturated vapor concentraton S.C. Sensitizer SlllcoaU Slurry So Utility In water Solution Specific chsmicel identity Specific gravity Spill or leak Spontaneously coatoustibl* materials The concentration .-of vapor at equilibrium with the liquid phase at 20*C (68*F) and standard atmospheric pressure expressed in milliliters per eubic sitter (expressed in ppm). This concentration nay be calculated from the vapor pressure <VP) of the l iquid at 20*C (60"F). The general formula is the vapor pressure divided by the standard atmospheric pressure and eultiplied by a million. If the vapor pressure is expressed in millimeters (am) of mercury the calculation would be VP (in mw>ir $VC (in ppa). (9) 700 Subcutaneous. An adalnietreticn of materiel dene below the layers of the skin. Eli A ehemieal that causes a substantial proportion of exposed people or animals to develop an allergie reaction in normal tissue after repeated exposure to the chemical. 12] LAY LANGUAGE DESCRIPTION: allergen, cause allergic reaction, rash A disease of the lungs (fibrosis) cauaad by the inhalation of ailiee duet. See pneuBoconloele. (23 A pourable suspension of a solid in a liquid. (1] A term expressing the percentage of o uteri el (by weight) that will dissolve in water at aabiant tm^eratur*. SolXillty information can be useful in determining spill cleanup methods and extinguishing agents and methods for a material. [2] Any homogeneous litgiid mixture of two or more ehemieal L'laqjuuvie or elements that will net undergo any segregation mder conditions normal to transportation. C9] The ehemieal name, ehemieal Abstracts Service (CAS) Registry lumber, or any other information that reveals the precise chemical designation of the sibotanet. (61 The weight of a material ujqmi ed to the weight of an equal voliae of water is an expression of the dsnsfty (or heaviness) of a materiel. Inedible materials wieh pacific gravity of loos then 1.0 will float in (or on water). Ineolible materials with specific gravity greater than 1.0 will sink In water. Moat (but not ell) fimmmble liquids hove specific gravity teas than 1.0 and, if net aolibla, will float an water -* an important consideration for fire expression. C21 The mathodi, equipment, and precautions diet should be used to control or clean ip a look or spill. CZ) Spontaneously ccebustible material (solid) means a solid sdatmei (including sludges and pastas) which may mdsrgo spontaneous hooting or aolf*ignition under conditions normally tneidsnt transportation or which moy xon contact with the atmosphere undergo VW 000010929 teem DEFINITION MSOS GLOSSARY (Continued) P*9 24 Stability STEL Strong oxidizer Subehrenie (health effect) an incroeso in te^eracure and ignite. See fl--sable solid. 9] The ability of a Material to reMoin unchanged. For MSOS purposes, a material is stable if it remains in the same foro inder expected and reasonable conditions of storage or use. Conditions that nay cause instability (dangerous change) are stated; for example, teaperatures above 150*F; shock from dropping. [2] Short term exposure limit. See TLV. A chemical that promotes oxidation readily and, on contact uith combustible material, nay cause fire. (33 It is the health effect occurring as a result of the repeated daily exposure of experismntal animals to a chemical for port (approximately 10 percent) of a life span. S.U.S. Synergism S.U.S. means Seybolt Universal Seconds as determined by the Standard Method of Test for Seybolt viscosity (ASTM 088*56) (reapproved 1968) and may be determined by use of the S.U.S. conversion tables specified in the Standard Method for Conversion of Kinematic Viscosity to Seybold Universal Viseosity or to Seybolt fural Viscosity ASTM 02161*79 following determination of viscoeity in accordance with the standard Teat Method for Kinenotlc Viscosity of Transparent and Opaque Liquids (and the Calculation of Oynanic Viscosity) (ASTM 0445*79). [91 The cabined action of agents (chemicals) so that their joint offset is greater than the sue of their individual affect. (11] LAY LANGUAGE DCSCRIPTlONi and react teoothor to be Systemic toxicity Tachycardia Targat orgM offset TCC TOC Toretogen Adverse effects caused by a substance that affects the body in a general rather then local mmtnar. (2] LAY LANGUAGE DESCRIPTION: Effects distant from contact or application aits. A very rapid heart rata. (1] The effect of a material an an organ or system. Usually predicted from animal toxicology trials or evidenced from actual hu--i exposures. The offsets can be a result of direct contact with the organ or through systemic toxicity. QSNA provides examples of the types of target organ affects in Appendix A of the Standard. (1) Tegllobue Closed Cup, e standard method of determining flash point. Tagliabue Open Op, a standard method of determining flash point. A material which has the capability of causing melformations in the offspring ss s result of exposure to the pregnant female. (1] VVV 000010930 TERM DEFINITION MSOS GLOSSARY (Continued) Page 25 Teratology Tinnitus TLV Toxic cheatcal -QSKA SAM Toxicologist LAY LANGUAGE DESCRIPTION: Nay causa birth defects The study of birth defects (includes both structural and behavioral) (1] Ringing in the ears, or other noises like a bussing (1) LAY LANGUAGE DESCRIPTION: Rineino in ears Threshold Limit Value. Developed by ACG!H*recoManded limitation for a materiel at or below Wiich workers should have no health problems. TLV's are expressed as a timeweighted average (TUA) for an 8-hour day, as a short tens exposure limit (STEL) naxina 15 minute exposuresCno more than 60 minutes/day), or as a ceiling value (Cfc) which is not to be exceeded wider any condition. Soma TLVs have a "skin*1 notation which indicates that the materials readily absorb through the skin and may represent additional expoaura by this route. The TLV's ore presented in the annual publication, Threshold Limit values and Biological Exposure Indicias for 19XX. CD A chemical that falls within any of the following categories: (1) A chemical that has a median lethal dose <LD.O) or more than 50 milligrams per kilogram, but no more than 500 milligrams per kilogram of body weight, when adsinistered orally to albino rats weighing between 200 and 300 grams each (2) A chemical that has a median lethal dose (LD.0) of more than 200 milligrams per kilogram, but no more than 1000 milligrams per kilogram of body weight, when adsinistered by continuous contact for 2t hours (or less, if death oeeurs within 26 hours) with the bare skin of albino rabbits weighing between 2 and 3 kilograms each (3)A ehemical that has a median lethal concentration (LC0) in sir of more than 200 parts per million (ppm), but no more then 2000 ports per million (ppm) of gas or vapor by volume, or more than 2 milligrams par liter, but no more than 20 milligrams per liter, of mist, fume, or duet, Wien adsinistered by continuous inhalation for 1 hour (or less, if death occurs within 1 hours) to albino rats weighing between 200 end 300 grams each. C6) A chemical so designated wider Section 313 of SARA Title til. Its release into the envirensent must be reported annually to the EPA and to designated State officials. The presence of a toxic chemical in a mixture or trade name product must be notified to customers. This notification must be incorporated into or attached to the MSOS for that product. A scientist specializing in the study of the adverse effects of chemicals in animals. Ill TOO Threshold Planning Quantity. The quantity of a SARA extremely hazardous stdetance that If equaled or exceeded at a facility triggers emergency planning provisions. (9) Trade secret OSHA Trade secret means any confidential formula, pattern, process, device, information or compilation of information that la uaad in an employer's business and that gives the employer an opportwiity to obtain an advantage over ecspetitore who do not know or use VVV 000010931 TERM DEFINITION NSOS GLOSSARY (Continued) Page 26 -SARA it. The cheaical manufacturer, iaporter, or employer nay withhold the specific chemical identify, including the cheaical naae end other specific identification of a hazardous cheaical, from the materiel safety data sheet, provided that: (1) The claim that the information withheld is a trade secret can be supported; (2) Information contained in the materiel safety data sheet concerning the properties and effects of the hazardous chemical is disclosed; (3) The materiel safety data sheet indicates that the specific chemical identity is being withheld as a trade secret; and, (A) The specific cheaical identity is mode available to health professional, employees, and designated representatives in accordance with the requirsaants of 29 CFR 1910.1200. (5) "Trade secret11 under SARA, mesne any confidential formula, pattern, process, device, information or eoapi lotion of information that is used in e subsittsr** business; and that gives the siteitter an opportunity to obtain an advantage over competitors t*o do not know or use it. CPA intends to be guided by the Restataaane of Torts, section 757, conmnt b. (9) TSCA Toxic Sitetancee Control Act (administered by CPA) regulates Introduction into SSBBCSMJBA the manufacture, handling, jf|j| use of materials. (1] TSCA inventory A list of chemical sttetancee that may be manufactured, imported, processed or uaed in the United States for conereial purposes. The initial Inventory was ccapiled in 1977; additions to the Inventory are mads by premanufacturing notifications. tIJ TUA Tima-weighted average. Sea Tiv and PEL. (2) URL or UFl Upper explosive limit or ipper flammablo limit of a vapor or gas; the highest concmttration (highest percentage of the substance In air) that will prtejee a flash of fire tten an ignition source (heat, ere, or flan) is present. At higher concentrations, the mixture is toe "ruch" to bum. Also see LEL. (2) UN Heater Unstable {reactive) Urticaria UV Vapor An identification ruter aaaignod by tho Uni tod Rations to hazardous materials in transportation. They ere used to readily identify hazardous motorists in transportation emergencies. Those preceded by "NA* ere associated with descriptions not rocognlzod for intomotionsl shipments, except to and from Canada. "(10)* A chemical *iich in the pure state, or as produced or transported, wilt vigorously polywlio, decompose, eendanao, or wilt become eelf-reeetive inder conditions of shocks, pressure or temperature. (61 An allergic akin condition characterized by hives or blisters. (1] UT LANGUAGE DESCRIPTION: Rash or hives Ultraviolet. Radiation in the region of tho electromagnetic spectrin including wavelengths from 100 to 3900 A. C] The germft form of e chemical that may diffuse and that is normally in the solid or liquid stato. (3) vw 000010932 TERM DEFINITION USDS GLOSSARY (Continued) Pig* 27 Vapor density Vapor pressure Viscosity Water resetive eoterial -OOT Water reactive chasncsl -OSHA UEEL UNMIS The weight a vapor or gee as coopered to a standard, usually air. Heavy vapors My tend to cling to the ground and concentrate, therefore having a potential for health or physical da--gt. Cl] Tha pressure exerted by a saturated vapor above its own liquid in a closed container. When quality control tests are perfonaod on products, the test taaperature is usually 100*F, and the vapor pressure is expressed as poinds per square inch (psig or psia), but vapor presaures reported on NSDS's are in eilli--ters or Mrcury <--Hg) at 68*F (20*F), unless stated otherwise. Three faets are iaportant to rea--Per: 1. Vapor pressure of e siPetance at 100*F will always be higher than the vapor pressure of the substance at 6ft*F (20*C). 2. Vapor pressures reported on MSOS's in aeMg are usually very low pressures; 760 a--g is equivalent to 14.7 pounds per square inch. 3. Tha lower the boiling point of a ttAatance, the higher its vapor pressure. (2] The tendency of a fluid to resist intemsl flow without regard to its density. (21 Any solid substance (including sludges and pastes) which, by Interaction withe water is likely to becc-- spontaneously flaa--ble or to give off flaa--ble or toxie gases in dangerous quantities. (See Fla--able solid). C9] A chenical that reacts with water to release a gee that is either flaapeble or presents a health hazard. (6] Workplace Enviro--ntal Exposure level guides are established by the AINA (AA--Mean Industrial Hygiene Aaaociateion) UEEl Co--ittee for substances which do not have exposure guidelines established by other organizations (see TLVaj. All nELs are expressed as ti---weirfited average (TWA) concentrations; however, different ti-- periods are specified depending on the properties of the --terial. Workplace Hazardous Materials Infer--tion Syst--. A Canadian nationwide eyat-- to provide infer--tion to workers on hazardous --terials usad in the workplace through the --e of MOSs. It Is the Canadian counterpart of tha OSHA Hazard Ccaiaurication Standard, but has different provisions end interpretations. VVV 000010933 TERM definition MM ClMtWT (CantfflMd> P-- 28 1. Chemical Manufacturer's Association, MSOS Workgroup 2. MSDS Glossary from Hazard gaurnmnlcatlon - A Compliance Kit. GPO NO. 929-022--9; OSHA No. 3104, 1988 3 American National Standard for Hazardous Industrial Chemicals - precautionary Labeling. Z129.1-1988, Copyright 1988 ansi 4. Hawley, G. G., editor, The Condensed Chemical Dictionary, nth Edition, Copyright 1987, Van Nostrand Company, Inc. 5. Websters Ninth New Collegiate Dictionary. Copyright 1989, Merriam Webster, Inc. 6. OSHA Hazard Communication Standard, as ammended August 24, 1987, see Code of Federal Regulations. Title 29. 7. V.rschueren, K., Handbook of Environmental Data on Organic Chemicals. Second Edition, Van Nostrand Reinhold Company 8. Taylor, E. J., editor, norland's Illustrated Medical Dictionary. 27th edition. Copyright 1988, W. B. Saunders Company 9. Code of Federal Regulations, Title 49, Department of Transporation 10. chemical Manufacturers Associaton. (848) Working Paper, ANSI Product Data Team. 1988 11. norland's Pocket Medical Dictionary. 24th Edition. Copyright 1989, W. B. Saunders Company, Philadelphia $2. vvv 000010934 TERM DEFINITION USDS GLOSSARY (Continue) PH* 29 12. National Fire Protection Association, WFPA-49. 9th Edition Copyright 1975 by National Fire Protection Association. 13. Provisional OECD Data Interpretation Guidelines, 1984 VVV 000010935 Appendix 1 ANSI 2129.1-1988, KA2ATO KVAWATItW AMERICAN NATIONAL STANDARD Z129.MMS Health hazard evaluation. For the purposes of this labelini standard, a health hazard evaluation is the process of using professional judgment to determine If an expo sure to a material could cause adverse human health effects under customary or reasonably foreseeable use or misuse, and thus if it is appropriate to provider a warning on a label about such hazard. This procaas consists of two steps. The first step involves a careful review of appropriate scientific studies to determine which reported effects are probable human effects. Probable effects include immediate effects reported to occur in animals, wellknown human effects (not including isolated case re ports4), end well-documented delayed effects reported to occur in animals and thst would be expected to oc cur in humans under comparable conditions. Organ/ system effects seen only near death and that are not the primary cause of death should not be considered. Probable human effects may be determined from other scientific data. If available data on human experience establish results different from those obtained on ani mals. the human data shall take precedence. There may be materials that cause effects at inordi nately high doses, under unusual conditions, or in other unique circumstances. The retstive weight of such information should be considered in making a health hazard evaluation. The second step in this process involves performing an assessment of the potential for exposure in order to determine If a hazard exists under customary and rea sonably foreseeable use or misuse. This testament must take into account the physical properties of the material, reasonably foreseeable conditions of handling, anticipated routes ofexposure, and availability for exposure. The health hazard evaluation should support the deci sion whether precautionary labeling is or is not to be used. *Caa reports thst So not pro*Ids s sritittiflc link httwvn the chemical and the advent health effect mould not be included so port of tht health hasard evaluation. Appendix 2 APPENDIX B tD CFR 1910.1200 HAZARD DETERMINATION (MANDATORY) Ibadiabtyafabafiidaemnaateattoa fnfn la Jatvtly dapaadaat apoa tbt adaqaocy aad Money aftba fcasaid dataraitnattan TW hoard da^aiLnatlfi tayrimnintafthlaattadaadlapartmnaacaariaaiad. Chamlcal rasoiactafaxa.4Bpan0a. aad amplifyaw aaatandat ctnkakm not aaaafcad to fafloar pay ayactfk --Undo far daiimiwan hatful. batthaymaat ha atria m dwimurata that i>y htaa adanaanfr aaaartatnad tba hauida ofAt abamteab paducad or topottad to a rr nrdanra arid) IN arttaria at teeth b> Ate appanrth Hoard avtlaatlen la a pocaaa which fattaa haarife ao tba pnfaaarimal Jadpamtf af tba aaahwtor. yariKalafty to tin ana of cfcnafe r--m yanwaaoa rttitm af th> tow daqr f tba cfeamkal namdaetora. tmyariw arampJoyar la aoadKt a thoraafk awlaaiiaft ruaiwle att rdrraat data aad PWm^i HHiamiqr mmm BfMaMM of iWa ataadaad. 1 flwftwpawwfrr Aa daacribad la fomfrayfc (oK4| aad Appaadte A of Ala lartina a datarmbaHna by tha National Tamnalaty Pragma. dm Iniamattooal Afaacy far ftaaaawb aa Caaeor. ar OAKA Mat a ebaaical tea wrinmaw ar yafttal aridaaea far parpoaa* f Mia faction. A Marat ate* Wbaw available. aaUaadabffaal atadlaa and aaaa aaportt of adaana hart* adacm rirnlt ba mMead la Matvalaattaat AAaMm/draHuaavtfaBaaofhaal* Maoa la eqnaad popniatlaaa la ramallr a* available for tba majority ofraaricab aaadaaad or--ad la M wniaiilana IbataCofa. dm oaMWUo laaoha of taataoto0oa) laatm* in animal popdotlooa ahatt bt anod ta predict dm health affiaeia dmi nayhae*partaModbyaxpaoadworimra.jB MWalar. the da&aitJooa of eariala aorta Ciardi wiar m aparidc animal manat monte (am Appendix A). AAdbaaaBjranrfiaparridyafdmalBo maateafaayataihm which atadaalppad aad aaadactad aaaoadina to aatabHabad artandfk prtaclplaa. aad whkh rayari riottaticaUy rtmuncmt cawclnrtawa waaidlm dm health osaels af a chamtcoL abafi ba a aoftdost bote far a board damrmlaatlaa aad taperwd on any malaria] ealaty dau abaat Tba Aaalel waiurfociaret. Impawn. ar amaloym may atoo tapan dm raaalta of ethar arteitlflcaUp yalld atadieo which load la adrte tfca fiadi&ta cf haxard. Z-l VVV 000010937 Appendix 3 STATE AGENCT RIGHT TO KNOT CONTACTS VVV 000010936 ALABAMA DEPARTMENT 07 ENVIRONMENTAL MANAGEMENT Office of General Counsel 1751 Federal Drive Montgomery, AL 36130 (205) 271-7700 Contact: E. John Wiliford-. ALASKA DEPARTMENT 07 LABOR Division of Labor Standards and Safety P. O. Box 1149 Juneau, AK 99802 (907) 465-4855 Contact: Edith Brand CONNECTICUT 8TATB 077ZCE8: DEPARTMENT 07 LABOR OSHA Division 200 Folly Brook Blvd. Wethersfield, CT 06109 (203) 566-4550 Contact: Emil Caruso DEPARTMENT 07 ENVIRONMENTAL PROTECTION 165 Capitol Avenue Hartford, CT 06106 (203) 566-8604 Contact: Laurie Boynton (203) 566-5524 Contact: William Delaney BUREAU 07 THE STATE 7IRE MARSHAL 294 Colony Street Meridan, CT 06450 (203) 238-6046 Contact: Robert Rakauskaus LOCAL OT7ICB8 DANBURY City Clerk's Office 155 Deer Hill Avenue Danbury, CT 06810 (203) 797-4515 DELAWARE DIVISION OF PUBLIC HEALTH Bureau of Environmental Health Jesse S. Cooper Building Federal and Water Streets Dover, DE 19901 (302) 736-3839 (800) 554-INFO (in Delaware) Contact: Randall Hair FLORIDA 8TATE OFFICES: DEPARTMENT OF LABOR AND EMPLOYMENT SECURITY 204 Lafayette Building 2551 Executive Center Circle w. Tallahassee, FL 32301 (904) 488-3044 (800) 367-4378 (in Florida) Contact: Reinaldo Manzo LOCAL OFFICES: PALM BEACH COUNTY County Health Department 901 Evernia Street West Palm Beach, FL 33402 Attention: Environmental Sciences and Engineering (305) 820-3070 HAWAII DEPARTMENT OF LABOR Education and Implementation Branch 677 Ala Moana Blvd., suite 910 Honolulu, HI 96813 (808) 548-7510 Contact: Ellen Kondo ILLINOIS TOXIC SUBSTANCES DIVISION Alzina Building Fifth Floor North 100 North First Street Springfield, IL 62706 (217) 782-4102 Contact: Thomas R. Wallin Public Safety Div. Administrator 3-2- 00I0939 INDIANA DIVISION OF LABOR 100 North Senate 1013 State Office Building Indianapolis, IN 46204 (317) 232-4135 Contact: Vick Hoberty IOWA BUREAU OF LABOR 307 East Seventh Street Des Moines, IA 50319 (515) 281-3606 Contact: Donald Petty KENTUCKY STANDARDS COMMISSION Department of Labor The 127 Building Frankfort, KY 40601 (502) 564-6895 Contact: Guy Schoolfield LOUISIANA DEPARTMENT OF PUBLIC SAFETY AND CORRECTION Office of state Police Hazardous Materials Section p. o. Box 66614 Baton Rouge, LA 70896 (504) 925-6113 Contact: Kendall Fellon MAINE BUREAU OF LABOR STANDARDS Station 45 State Office Building Augusta, ME 04333 (207) 289-2591 Contact: Lance Gurney MARYLAND DIVISION OF LABOR AMD INDUSTRY 501 St. Paul Place Baltimore, MD 21202 (301) 333-4182 Contact: Uliana 0*Brian SUBMIT LISTS AND MSDSs TO: MARYLAND DEPARTMENT OF HEALTH AND MENTAL HYGIENE Divisions of Environmental science and Technology Office of Environmental Programs 201 West Preston Street Baltimore, MD 21201 (301) 225-6493/6499 Contact: Anita Meros MASSACHUSETTS DEPARTMENT OF LABOR AND INDUSTRIES Right-To-Know Office 100 Cambridge Street, Room 1107 Boston, MA 02202 (617) 727-5816 Contact: Joe Belloli DEPARTMENT OF PUBLIC HEALTH Right-To-Know Office 150 Tremont Street Boston, MA 02111 (617) 727-2660 Contact: Dr. Marybeth Smuts DEPARTMENT OF ENVIRONMENTAL PROTECTION 1 Winter Street Eighth Floor Boston, MA 02108 (617) 292-5810 Contact: Arnold Sapenter VVV 000010940 3-3 MICHIGAN DIVISION OH OCCUPATIONAL HEALTH Department of Public Health P. 0. BOX 30035 Lansing, Ml 48909 (517) 335-8250 Contact: Flint Watt SAFETY, EDUCATION AND TRAINING DIVISION Bureau of Safety and Regulation Department of Labor 7150 Harris Drive P. O. Box 30015 Lansing, MI 48909 (517) 322-1809 Contact: Edward Fredericks FIRE MARSHAL DXVI8ION Hazardous Materials section State Police 7150 Harris Drive Lansing, MI 48913 (517) 322-1924 Contact: Art Nash MINNESOTA DEPARTMENT OF LABOR AND INDUSTRY 444 Lafayette Road St. Paul, MN 55101 (612) 296-2116 or 297-3254 Contact: Patty Lorenez DEPARTMENT OF HEALTH 717 Delaware Street, 5E Minneapolis St. Paul, MN 55440 (612) 623-5352 Contact: Dave Gray DEPARTMENT OF PUBLIC SAFETY Transportation Building, 2nd Floor St. Paul, MN 55155 (612) 643-3000 Contact: Lee Tischler riT) /i, \1) HIggpgB1 NATURAL RESOURCES DEPARTMENT OF LABOR AND INDUSTRIAL RELATIONS P. O. Box 59 Jefferson City, MO 65104 (314) 751-7929 Contact: Dean Martin 11 u w MONTANA DEPARTMENT OF HEALTH AND ENVIRONMENTAL SCIENCES Cogswell Building Helena, MT 59620 (406) 444-2630 Contact: Ellie Parker NEVADA DIVISION OF OCCUPATIONAL SAFETY AND HEALTH 1370 South Curry Street Carson City, NV 89710 (702) 885-5240 Contact: David Going NET HAMPSHIRE DEPARTMENT OF LABOR Inspection Division 19 Pillsbury Street Concord, NH 03301 (603) 271-3176 Contact: James McDonough MEW MEXICO OCCUPATIONAL HEALTH AND SAFETY BUBBAU Environment Improvement Division P. O. Box 968 Santa Fe, NM 87504 (505) 827-2873 Contact: Warren Slade 3-9 WV 000010941 HBW YORK FOR WORKPLACE ENFORCEMENT: DEPARTMENT OF LABOR OSH Intergovernmental Relations Room 579 State Office Building Campus Albany, NY 12240 (518) 457-3518 Contact: Robert Gollnick FOR PUBLIC EMPLOYEES ONLY: DEPARTMENT OF HEALTH New York State Department of Health Bureau of Occupational Health 2 University Place, Room 155 Albany, NY 12203-3313 (518) 458-6228 Contact: John Bintz NORTH CAROLINA STATE OFFICES$ DEPARTMENT OF LABOR Occupational Safety and Health 214 West Jones Street Raleigh, NC 27603 (919) 733-2658 Contact: Ann Wall LOCAL OFFICESt DURHAM Office of the City Clerk P. O. BOX 1086 Durham, NC 27702 (919) 560-4166 NORTH DAKOTA WORKMAN'S COMPENSATION BUREAU Russell Building Highway 83 North 4007 North State Street Bismark, ND 52505 (701) 224-3886 Contact: Roger Rohrer OFFICE OF THE STATE FIRE MARSHAL Box 1292 Bismarck, ND 58502 (701) 224-2435 Contact: Bob A11en UD U=u if OREGON DEPARTMENT OF INSURANCE & FINANCE Oregon OSHA Salem Central Office Labor and Industries Building Salem, OR 97310 (503) 378-3272 Contact: Jay Flack-Pennington FOR COMMUNITY PROVISIONS: State Fire Marshal 3000 Market Street, N.E. Suite 534 Salem, OR 97310 (503) 373-1276 Contact: Ray Stroud PENNSYLVANIA STATE OFFICES: DEPARTMENT OF LABOR AND INDUSTRY Room 1404 Labor and Industry Building Harrisburg, PA 17120 (717) 783-2071 Contact: Jeanette Blackstone LOCAL OFFICES: PHILADELPHIA Department of Public Health Air Management Services 500 South Broad Street Philadelphia, PA 19146 (212) 875-5623 ?? PUERTO RICO DEPARTMENT OF LABOR AND HUMAN RESOURCES Prudencie Rivera Martinez Bldg 505 Munoz Rivera Avenue Hato Rey, PR 00918 (809) 754-2188 Contact: Filiberto Cruz Aguila RHODE ISLAND DEPARTMENT OF LABOR Division of Occupational Safety 220 Elmwood Avenue Providence, RI 02907 (401) 457-1847 Contact: Anthony DiCicco VVV OOOOIOV42 -( Tgyyggpgg DEPARTMENT OP LABOR OSHA Division 501 Union Building Nashville, TN 37219-5389 (615) 741-7151 Contact: Bob cooper TEXAS BUREAU OP ENVIRONMENTAL HEALTH Department of Health 1100 West 49th Street Austin, TX 78756 (512) 458-7410 Contact: Paula McKinney VERMONT DIVISION OP OCCUPATIONAL AND RADIOLOGICAL HEALTH 10 Baldwin Street Montpelier, VT 05602 (802) 828-2886 Contact: Raymond McCanlis YIlWnflA OCCUPATIONAL SAFETY AND HEALTH Department of Labor and Industry P. 0. Box 12064 Richmond, VA 23241 Contact: Eve Byrd WASHINGTON ______ DIVISION OP INDUSTRIAL SAFETY AND HEALTH Department of Labor and Industries P. O. BOX 207 Olympia, wa 98504 (206) 753-6497 Contact: Steve Cant DEPARTMENT OF ECOLOGY Mail Stop P.V. 11 Olympia, WA 98504-8711 (206) 459-6322 Contact: Idell Hansen 'll! l?\ iC rL'L ^ WEST VIRGINIA DEPARTMENT OP LABOR 1900 Washington Street East Building 3, Room 206 Charleston, WV 25306 (304) 348-7890 Contact: William D. Hoffman FOR COMMUNITY R-T-K ACT: DEPARTMENT OF HEALTH Office of Emergency Assistance State Capital Building Room EB80 Charleston, WV 25305 (304) 348-5380 Contact: Bill Jopling FOR MEDICAL INFORMATION REPOSITORY: DEPARTMENT OP HEALTH Emergency Medical Services 1800 Washington Street East Charleston, WV 25305 (304) 348-3956 Contact: Fred Cooley WlgCQMga DEPARTMENT OP INDUSTRY, LABOR, AND HUMAN RELATIONS Safety and Buildings Division 201 East Washington Avenue P. O. Box 7969 Madison, WI 53707 (608) 266-2780 Contact: Jack Borders ffiWmW OSHA Herschler Building 122 W. 25th Street Cheyenne, WY 82002 (307) 777-7786 Contact: Joe Borghi WV 000010943 3-(o TO: Nick Semenza - Blane (via Fax) XF: Communication FROM: DATE: SUBJ: T. G. Grumbles January 8, 1990 MOHAWK WIRE & CABLE CUSTOMER HEALTH ALLEGATION I VISTA I spoke with Jim Baker on Friday. What he needs is a letter that gives the information on our analysis and conclusions, but stated in terms of investigating a skin rash complaint not an inhalation problem. He understands that we would do the same type of product analysis to investigate potential causes of either type allegation. He *also stated that the employee complaint was from employees handling their product on the "cold side" of the process. Basd on my discussion with him, I would suggest you write him a letter similar to the one you sent previously (I assume you've sent one) but stating we did the analysis to investigate potential product contamination that might result in product differences which could cause skin rash problems described to us. Give me a call with any questions. T. G. Grumbles dlj cc: Carl Tomanek - Austin VVV 000010944 DEC-11-'00 NON 15:25 ID:UISTA R&D Ws-wrt, TEL NO:512-331-238' #317 P02 TO: FROM: DATS: N. semenza - Blane vC, Tomanek - Austin November 29, 1989 SUBJECT: ANALYSIS OF CABLE FROM MOHAWK W&C you recently sent me a sample of cable made by Mohawk Wire & cable Company jacketed with Blane 34311. You said that the operators terminating the cable in a molding operation, were experiencing an obnoxious odcr during the molding cycle and became sick. You asked the laboratory to analyze the cable for anything unusual. The cable is about 5/8 inch in diameter with a metal braid under the jacket. The jacket is about 63 mils thick. The core is made up of twisted pairs of #24 AW6 stranded, tinned, copper conductor insulated with FVC compound. This core is over wrapped with a clear film wrap. Our investigation found nothing unusual about the PVC compound used to insulate the conductors and jacket the cable core. The cable jacket compound is PVC with a linear phthalate plasticizer. It is filled with aluminum trihydrate and stabilized with a lead stabilizer. An FTIR (Fourier transform infrared) spectra of the jacket material made from a thin film is attached. Analysis of extract of the cable jacket by gas chromatography showed no unexpected components. The insulation compound was also analyzed by FTIR. This material is a PVC plasticized with a linear trimellitate plasticizer. There is no evidence of anything out of the ordinary indicated in this spectra, (attached) I would suggest that before going any further in attempting to identify the problem by analysis, that some one go in and see if the customer may be experiencing a molding problem causing degradation of the material. Air samples could also be obtained at the same time using draeger tubes. These could then be sent back to the laboratory for analysis. Also to continue investigating this problem, we should be looking at the molding material involved. At this point we have no further work planned for this problem. The analytical work discussed above was conducted by our analytical section: gas chromatograph - E. Sones, FTIR - Dr. Latimer. cc: HJH, SHH, ELS, TML VVV 000010945 nJ^r1 27.7 33.2 38. 1 nw r 7 y jw # jrlN a A U M ; o o ? i ;0 0 9 1 * 0 0 9 2 d q ^ z j p o g z ^ ;o o ? e r 0 0 9 E ; o q c n > 009 0d LXZU iB2-T-STS:0N 131 dfltf dlSIrVQI 9S=ST NOW 00t-TT-D3d DEC-11 -'00 MON 15:27 ID^ISTA R&D TEL NO:512-331-2387 8317 P04 * 1 6 - 7 9 - 2 HOHAUK CABLE HflVENUHBER L' 06 0*28 E'GZ. 9'*i9 B'SS 2*L* S'8E ! 30NUX1IWSNW91 % 8*B2 I'I2 vzf Thomas G. Grumbles To &>i\ vjayatN VIS1A ------- T6G; JCL ERT: MJH: AJO: RF Dote P\\\acV\eot 1,1<, f/i-e. \ev\ec_ ^surv,^ Vo ,C050L /^e^o.rLCi\ A tj, & u t\- 4on_ VW-t- LA^> Ja^o to i VVV 00001094a t-'-L-- KJ?' 341 lHtJJ ni.i- cnvtruin chiml urcr^m lUMi? nata<s Monsanto Monsanto Chemical Company 600 N k.indc*rgn Boulevard St. Louis. Missouri $3167 Phone (314) 634-1000 January 5, 1990 Keith Buckle, PhD Shell International Petroleum Maatschappij B. F. Health, Safety & Environment Division P. 0. Box 162 2501 AN The Hague Netherlands Council for LAS/LAB Environmental Research (CLER) Dear Keith: This letter represents CLER's response to your December 22 request for comment on selection of test material for our joint LAB dermal testing program. The position indicated below represents the consensus developed between CLER member companies after several discussions of the scientific issues related to test material selection. Our comments are based on the following premises: 1. The 90-day subchronic test previously conducted by ECOSOL will serve as a pilot for the proposed dermal chronic test regardless of which test substance we choose. 2. The MTD for the dermal chronic will be determined by the skin irritating nature of lab itself, rather than any property of non-LAB components. Thus the dose level would be the same for HF or AlCl3 material. This combined with the low recommended MTD of 5% from the subchronic, suggests that non-LAB component concentrations on the mouse skin would be so low that no differences in test response are expected. 3. We in the detergent industry draw a greater distinction between HF and AlClj-based products than do others; the regulatory community views all LAB as the same. WV 000010949 a urw H Mcmutniu CtfTqMny tas feD'D/ li.iJ.tJ ncc tfSV l KUHi'ltH 1 ML. UrtKHI 1 UINb UfcJO 4. An adverse toxicological finding on LAB from either process would also taint the other process, although possibly to a lesser degree. 5. There is sufficient biological variability in chronic tests that replicate tests on one product would not give identical results. Thus if we conduct chronic tests on two materials, even if the results are similar, some regulators or environmentalists can be expected to over-interpret subtle differences and unnecessarily discredit the product with the least favorable results. 6. Our primary objective is to address questions raised about LAB by publication of iversen's tests at overly-exaggerated dose levels. Of lesser importance is testing non-LAB components, which vary in concentration (and perhaps identity) from the different processes. 7. Many regulatory agencies, including the U.s. EPA, stipulate that industry consortia should test the purest available commercial product. 8. Positive (i.e. adverse) toxicological findings on mixtures are very difficult to interpret, and essentially guarantee the need to conduct more studies. With these premises in mind, we have commented on the options below. l. Test HF material only. There is no question the subchronic results would be applicable, and a finding of no adverse effects would clear LAB of concern. Toxicological interpretation would be less complex and selection would comply with regulatory precedent. Other Options; Teat a representative commercial 50;50 blend of HP and A1C13 Material. The results would be equally applicable to each process. Toxicological evaluation is more difficult. Humans are not normally exposed to blends. Test Alcij material onlvT a finding of no adverse results would clear lab and all non-LAB components, adverse results would be difficult to interpret. Test both products separately. Provides the clearest toxicological picture but probably not needed because no differences expected (see premise #2). Would add significantly to cost. Most likely to be perceived as unnecessarily differentiating the two processes, as described in premise #5. 00010950 iis 11 [ICC LNC I RUNIitN I HC UFbKHllUNb ldU4 CLER strongly favors option #1 and we are ready to proceed. If other companies have compelling reasons why one of the other options is preferable, we would be agreeable to listening to these reasons, although this would undoubtedly delay the project further* We look forward to resolving this sample selection issue so we can proceed with the testing. Sincerely James P. Mieure CLER Steering Committee VVV 000010951