Document 0dqvBoN1MjgzBZJE6wkrDqwb

.^X: *- 401, JO B. 42nd Si, Sr 1 *# fcllaa (2) Boot UO Bldg, ' t. J *. * ; , l' . ' * :. ;'r 1 . .- '. ., - ' Sot lark 17, I* JU fifamij 13,194S Bmt Sr* JbUitt Sr, Ome asks In hi* report of oall of 1/^48 to Corbett Clinic, Chicago, If Dr* Corbett*9 practice of applying our film VB-1925 and TB-1900 (dear directly to the akin In hia treatment of lwbago and sprain,, etc*, is dangerous. Would say that applying these film directly to the akin and keeping In continued contact nig ht lead to a dermatitis In tone fen individuals, partly because of the imperviousness of the filn and partly because of the sensitising action which the flln night cause In sane fen Oases* We have patch tested VU-1900 dear on 151 human subjects end found that In 13 per cent of then sene sensitisation reactions did occur* We hare not patch tested IB-1925, but have the basio resin,the IXHW, and found that it did eauoo a Slight reaction In 8 per cent of the subjects. Also the stabiliser used in IB-1925, even In 1 concentration on gause, caused definite sensitisation reactions in about $ percent of the subjects tested. However, should such sensitisation reactions occur during treatment such as Dr. Corbett is dairying out, they would probably disappear with no residual effects upon discontinuance of such treatment. So X would say that applying our films VB-1925 and rj-1900 dear directly to the skin is not dangerous, Such application night cause a dermatitis; in sene people, which would dear up in all probability upon discontinuance of the contact with the filn. Tory truly yours. T. W, Hale, M. D. b IHDUSTRIAb TOXECOLOGI DEPARE4EHT '* i -1 ucc 063514 W *LJ`.