Document 0Rzbak0xGRBdz92e0YnqBE1k

C P ICI Chemicals and Polymers Group Occupational Health Department Hillhouse Site P.Q. Box 4 Thornton-Cleveleys Blackpool FY5 4QD Telephone Facsimile (0Z53) 861632 Direct Line (0253) 861370 Secretary (0253) 861444 Switchboard (0253) 864687 Telex 67483 ICIPLH G To all recipients of the ASL Register Chemicals and Polymers Group Hillhouse Site Your ret Our ref BB/BGS Date Feb I9b7 Dear Colleague RESEARCH INTO ASL I am enclosing the latest edition of the ASL Register, dated February 1987, and am writing to ask for your co-operation with some research into ASL. While in the States recently, I visited Professor Carlo Tamburro, Professor of Medicine & Community Health; Acting Chairman, Department of Community Health; Chief, Division of Occupational Health; Director, Liver Research Centre, University of Louisville, Kentucky. We discussed VC clustering, and why some particular Plants, which have been manufacturing VCM/PVC pre-1962, have never had a case of ASL. As a result of our discussions, we had the feeling that, for ASL to develop, certain circumstances are required, and that a co-factor may be needed. I was wondering if you would be prepared to help in identifying such a factor? I am enclosing a pro-forma with certain chemicals mentioned, and I should be very grateful - if you are willing - if you would tick off the years in which any of the chemicals listed was used, if in fact they were used at all, and return the form to me. I would definitely communicate back to you with any results obtained, and with what conclusions Professor Tamburro and I have made. Before, however, releasing any information with reference to any of th completed questionnaires, I will contact the individual who is responsible for that questionnaire, in order to discuss that information further, and to seek an appropriate, acceptable way forward. 1 It should be remembered that this exercise is purely a research topic, and therefore may yield no positive results. I look forward to hearing from you and receiving your comments. Yours sincerely B BENNETT M.A. M.B., B.Ch., B.a.Q. D.Obst.R.C.O.G. D.I.H., M.F.O.M ir>i r>u_ rJ 15-1,.. -1 1 TM CMA 006481 RESEARCH INTO ASL Name of Company*: (*If Company ownership has changed, please give name of previous Company and dace of change.) Address: ............................................................. *................ Sice Location: .................. Form completed by:....................... (Block capitals, please) .... DaCe YEAR | VINYL VINYL HEXANE IdETHYLj PHENOL 1 BUTADIENE 1 TOLUENE 1 ACRYLATES I CHLORIDE ACETATE ImaleateI I | | 1939 III! Ill 1940 J___________ 1___________________ ___________ 1____________ ___________________ _____ 1941 1 1942 1943 1944 1 | III l l 1 i 1945 1946 I ___________ !__________ I_________ || 11 1947 III 11 1 1 1948 | 11 1 1 1949 1950 ___________ ___________ __________ _________ L ________________ 1 ! 1 1952 1953 1954 1955 1956 1957 1958 1959 | 1 1 | 1 I WPX/ASL - RESEARCH,! /Continued CMA 006482 RESEARCH INTO ASL Page 2 i * YEAR | VINYL VINYL HEXANE DIETHYL PHENOL BUTADIENE TOLUENE ACRYLATES I CHLORIDE ACETATE MALEATE 1960 ! I il 1961 1 1 !1 1962 ! 1 11 1963 1 1 1 ......J 1964 I I 1 ..J .....J 1965 1966 1967 1968 I 1...... 1 1 1 I 11 11 1 111 1969 I 1970 I I11 1971 11 1 1972 1 1 11 1973 1974 1 1 J11 I1 1| 1975 1976 1977 1 1... I 1 I I I1 | _________________ | 1978 1 11 I! 1979 1 1 11 1980 1 1981 1982 1983 1 ! 1 1 11 1| ________ 1984 J I Please return to: Dr Brian Bennett Occupational Health Department ICI Chemicals & Polymers Group Hillhouse Site PO Box 4 Thornton-Cleveleys BLACKPOOL FY5 4QD ENGLAND WPX/ASL - RESEARCH,2 CMA 006483 LIVER ANGIOSARCOMA CASES CCMFTDEMTIAL cmaoncN of register RAGSHAW DrIMM RAND Dr P R BARNES Jnr W C BARR Dr J T BARRAl Dr G BAXTER Dr Peter BAYLAC Dr BEADPRE M BELLEC Dr BENECH Dr M BENTETT Dr B BERXAZZI Dr P BESCHE Dr BISHOP Dr C BORRELLI F E BOYER R W BRYSON Dr D D BURGESS Mr David BYKEN Dr David CARTER Dr J T 05LLA Mr C CHANCE Mr M CLAUS Mr P G CLAYTON Mr H CONIASSOT Dr J C DAVIES Mr J G DEPLAN Dr DE VOS Mr A J DIEIZ Dr H W DOLL Sir Richard DOMBRCWSa S L DUPONT Mr G EWDEER Mr H ERiST Dr W EVANS Dr A E J FALK, Dr H FAVRE Dr FERGUSCN Dr D M FORMAN Dr D FRASE R W FRIEDEL Dr H P GCLBESG Prof L GOSZTONYI Jnr Dr GCTIEaJAN R T HARRIS Dr W D HILL Dr G B HILLMAN Dr D W HDDEKER Dr R K HOGG Dr W A ffiWARD Dr J K HUMPHRY Dr N F JAUVEKT Mr J JERVIS Mr H R JONES Dr R D Norsk Hjdro, Newton Aycliffe, UK Cancer Control Agency of British Colimbia, Vancouver, Canala Monsanto, St Louis, Missouri, USA Air Products, Allentcaai, Pa, USA AECHP, Cocmentry, France University of Cambridge, IK Atochem, Chauny, France Government of Quebec Cancer Registry, Canaia Rhone Poulenc, Aubervillers, France Naphtachimie, Lavera, France ICI HiUhouse, IK Inst of Occupational Health, Milan University, Italy Dynandt Nobel, Troisdorf, Germany EMAS, Cardiff, IK Georgia Gulf, Delaware City, USA Formosa Plastics, Delaware City, USA ICI Billingham, UK ICI Americas, Wilmington, Delaware USA Kemanord, Stockholm, Sweden EMAS, London, IK Enichem Polimeri, Milan, Italy ICI Runcorn, IK ABE, Brussels, Belgium Norsk Hydro, Newton Aycliffe, IK Atochem, Saint-Fons, France ICI, Everberg, Belgiun Atochem, Jarrie, France EVC, Welwyn Garden City, IK B F Goodrich, Akron, Ohio, USA Imperial Cancer Research Fund, Oxford University, IK Dew Chemical, Midland, Michigan, USA ABC, Brussels, Belgium VKE, Frankfurt, Germany Berufsgenosssischaft der Chanischen Industries, Nurnberg, Germany Lever Bros, Warrington, IK Gironde Diseases Dlv, US Dept of Health & Human Services, Atlanta, USA Atochem, Montluel, France ICI Americas, Wilmington, Delaware, USA Injjerial Cancer Research Fund, Oxford University, IK DiversiTech General, Akron, Ohio, USA Berufsgenossenschaft der Chemischen Indistries, Heidelberg, Gemany Duke Unlv Medical Center, Durham, North Carolina, USA R E Tenneco Chemicals, Piscatawey, New Jersey, USA The Vinyl Institute, Wayne, NJ, USA Uniroyal Inc, Middlebury, Connecticut, USA Alberta Cancer Board, Ednonton, Canada Diamond Shamrock Corp, Dallas, Texas, USA BF Goodrich, Cleveland, Ohio, USA Imperial Oil Ltd, Sarnia, Ontario, Canada University of Otago School of Medicine, Wellington, New Zealand ICI Australia, Melbourne, Australia Chloe Chtmie, Paris, France ICI Mi11bank, London UK EMAS, Bootle, UK WPX/ASL - ASL ADDRESS,1 CMA 006484 KARKH Dr Bruce KORSGAAFD Dr K J KREUGER Dr R A UGAST Dr H LALODE Dr J P LANHAM Dr John LANOUZIERE Dr LAWRENCE Mr J LAWRENCE-Jones LEE Dr F I LELBACH Prof WC LEVEQUE Dr G LEVISON Dr D A LEWIS Dr P LOUVIER Mr LUSSAID Dr J MAHEARD Dr J M MALHDISA Anna MAL1DNI Prof C MARGEIT5, Mr R J MATIRE Prof Lo MATITUSSI Dr R MIDDLETON D MKKA Mr MONIESAND Dr R M7ITI Dr A A MUIDZ MDUTCN Dr M MacSWEEN Prof RNM NAKAMJRA S OLSON H G OWEN Dr R PADDLE Dr G M PAGLIALUNSA Dr S PAQUET Dr PATERSON Dr J C PIRASTU Dr Roberta POPPER Dr Hans FOSSBERG Dr J RJECH Dr A M PURDHAM Dr J RAMBADD Dr J RAfCNES P RICHARD Dr P ROBSON Mrs D RODRIGUES Dr MJF ROUSH Dr G RLTIY Dr J SALG Dr J SARAOCI Dr R SCHEFFERS Dr M L SOHFPER Dr H SERONtE Dr D SHAH Dr Has SIGRIST Dr J SMITH Dr E SMITH Dr P M SMITH Prof Allan H SMITH Mr J S SPIOTAS Dr R STAFFORD Dr J STAHICCXER Mr -2- Dupont, Wilmington, Delaware USA Norsk. Hydro, Porsgrunn, Norway BF Goodrich, Akron, Ohio, USA Solvay, Brussels, Belgian Solvay, Brussels, Belgium Dow Chemical, Midland, Michigan, USA Solvay, Tavaux, France SPI, New York, USA Sir Christopher, Chief Medical Officer, ICI, London IK Victoria Hospital, Blackpool, Lancs, IK University of Bonn, West Germany CDF Chimie, AZF, Bully-les-Mines, France St Bartholomew's Hospital, London, UK Chemical Industries Association, London, IK Solvay, Brussels, Belgian Atochem, France Suva, Luzern, Switzerland Statistics Canada, Ottawa Institute di Oncolegia, Bologna, Italy ICI Directorate, Wilton HQ, UK Medil-Ardc-S, Milan, Italy Montedison, Milan, Italy Norsk Hydro, Newton Aydlffe, LK Neste Oy, Espoo, Finland IARC, Lyons, France Duperial SA1C, Buenos Aires, Argentina Rio Rodano, Madrid, Spain Western Infirmary, Glasgow, Scotland Japanese IVC Association, Tokyo VC Safety Association, Louisiana, USA Trades Union Congress, Lonlon, UK ICI Central Medical Group, Alderley Park, IK Montedison, Novara, Italy Atochem, Serquigny, France ICI Runcorn, IK Istituto Superiore di Sanita, Rome, Italy Mount Sinai Medical Center, New York, USA Wacker-Chanie, Munich, Germany Atochem, Brignoud, France Canadian Centre for Occupational Health & Safety, Hamilton, Canada RP Recherches, Antony, France Norsk Hydro, Porsgrunn, Norway Rhone Poulenc, Roussillon, France Saskatchewan Cancer Foundation, Regina, Canada Id, Sao Paulo, Brazil Monsanto, St Louis, Missouri, USA Atochem, St Auban, France NIOSH, Cincinnati, USA IARC, Lyons, France D31/CVM), Geleen, Holland University of Manitoba, Winnipeg, Canada Diamond Shamrock, Dallas, USA CMA, Washington DC, USA Shell Chimie, Bene L'Etang, France Division of Environnental Health, Wbrld Health Organisation, Geneva, Switzeriant Llandough Hospital, Penarth, IK University of California, Berkeley, USA Id Hillhoise, UK Nd/NIH, Bethesda, Maryland, USA Somerset, UK BASF, Ludwigshafen, Germaiy CHA 00648., WPX/ASL - ASL ADDRESS,2 TAMBUKRO Prof CH ten BERGE Dr W F TENQDFF Dr N TER HAAR Dr Gary 1ERWIESCH Dr B THERIAULT Dr Gilles THIESS Prof Dr A M THI1S-EVENSEN Dr E TEDMSCN Dr D H TORDOIR Dr W VAN DER MEKWE Dr WALLACE J R WALTEMAIE H WEUDLING S 0 WHEELER Dr D J WHEELER R N WHITE K H WILINSKI 0 WTLLIAEB Dr DHJ WILSON Prof R WRIGHT Dr A P YORK J -3- University of Louisville, USA D31, Geleen, Holland Huls AG, Marl, Germany Ethyl Corporation, Baton Rouge, Louisiana, USA Chenische Werke Huls, Kreis Recklinghausen, Germany McGill University, Montreal, Canada BASF, Ludwigshhafen, Germany Norsk Hydro, Porsgrunn, Norway Cancer Treatment & Research Foundation, Halifax, NS, Canada Shell, An Den Haag, Holland H J AECI, Sasolburg, South Africa Esso, Sarnia, Ontario, Canada BF Goodrich, Cleveland, Ohio, Usa Norsk Hydro, Stenungsund, Sweden ICI Hi11house, UC Union Carbide, South Charleston, USA Duperlal, Buenos Aires, Argentina Electrochemical Industries, Acre, Israel BP Chsnicals, Penarth, IK Harvard University, Cambridge, Massachusetts, USA ICI Wilton, IK ICI Everberg, Belgium From: Dr B Bennett, Occupational Health Department, ICI Chemicals & Polymers Group, Hilltouse Site, PO Box 4, Thomton-Cleveleys, Blackpool FY5 4CJ>, England February 1987 WPX/ASL - ASL ADDRESS,3 CHA 006-486 CONFIDENTIAL REGISTER OF CASES OF ANGIOSARCOMA OF THE LIVER DUE TO EXPOSURE TO VINYL CHLORIDE - REVIEW DATE 1 JANUARY 198? PREFACE : ACKNOWLEDGMENTS, SIGNIFICANT CHANGES, COMMENTS AND REQUESTS 1. The 10 new cases in the Register are the following: France 19, 20, 21; Germany 28, 29, 30, 31, 32; UK 13; USA 39* 2. There are amendments from the previous Register against the following cases: France 15; Germany 23, 26. 3. I would like to thank the following for informing me of new cases - Dr Contassot, Dr Barrat, Dr Landers, Dr Friedel, Dr Williams and Mr John E Ertel. 4. For the case corrections I thank Dr Contassot and Dr Friedel. 5. For other corrections and information thanks to Mr John T Barr, Mr John E Ertel, Mr R T Gottesman, Mr A King and Dr N A Sulaiman. 6. I should be very grateful if all recipients of the Register could continue to keep me fully informed of any new cases or, if th y hear of other Companies who have acquired a case of ASL, it would be much appreciated if I could be notifi d by the appropriate person. It is very helpful if new information is supplied in tabulated form, using the h adings in the Register as far as possible. For this purpose I have added a blank form at the back of the Register. 7. I would also be glad of help to keep the mailing list correct, with news of retirements and successors, etc. 8. Research: (a) I am enclosing a letter which explains a research project in which I and Professor Carlo Tamburro hope you will be able to co-operate in the interest of knowledge. (b) I shall be very grateful if all individuals involved in research or surveys could keep me informed and if possible send me copies when they become available. From: Dr Brian Bennett Occupational Health Department 1CI Chemicals & Polymers Group Hillhouse Site P 0 Box 4 Thornton-Cleveleys Blackpool FY5 4qd England February 198? rMA 006487 ICI CHEMICALS & POLYMERS CROUP WPX/ASO - LANCIOCASES,4 I ndex LIVER ANGIOSARCOMA CASES (REVIEW DATE - I JANUARY 1987) Table Sequence Page Page Belgium Canada Czechoslovakia 1 ASL Case Numbers by year of Death (Table 6) 2-3 ASL Case Numbers by year of first exposure 4 (Table 7) 44 45 France Germany Italy 5-9 10-15 16 Western Europe PVC Producers - Start-up Dates vs ASL Cases (Table 8) USA PVC Producers - Start-up Dates vs ASL Cases (Table 9) Ub 47+48 Japan Norway Sweden 17 Canadian PVC Producers - Start-up Dates vs ASL Cases 49 (Table 10) 18 East European PVC Producers - Start-up Dates vs ASL Cases 50 19 (Table 11) UK USA Yugoslavia 20-23 24-30 31 Japanese PVC Producers - Start-up Dates vs ASL Cases (Table 12) South A Central American PVC Producers - Start-Up Dates (Table 13) 51 52 Incidence of Cases per annum (Table i) Distribution of Cases by Country (Table 2) Pattern of Cases by Factory (Table 3) Latency Periods (Table 4 A) 32 33 34 35 Australasian PVC Producers - Start-up Dates (Table 14) Middle Eastern PVC Producers - Start-up Dates (Table 15) Blank form for notifying new cases 53 54 - CMA 0 0 6 4 8 8 Distribution of Latency Periods (Tables 4B-4H) 36-42 Annual Geographies 1 Incidence (Table 5) 43 r**.* 1 HMi.HIM it I CHEHICAiS K POLYMERS GROUP I.JVKR AnrI iianrt <ma Cnaet* - (Review Hate : I January I9A7) UP X f AM - LAN4.LOI.ASe S tt\ CMA 006-489 HHINTRY ANII H h h> RENCt NO NAME OR INITIALS DATF. OF BIRTH 12.01.n Solvay 02 SR 29 09 90 Solvay \ FIRST VC FACTORY | EIFOSUAE DATf. OF DIAGNOSIS Jeaeppe | 00.07.Sfl I Jewppe i 20 06 62 00.10.79 ACE AT DIAGNOSIS 9 YF.ARS OF EXPOSURE TO DIAGNOSIS 10 1 L1 1 YEARS OF | DATE OF FAPOSURE | DEATH i 1 ia I \ I I I I I I i 19 L 7 I 1 I t 17 9 t 1 129.06.76 1 1 1 t l 1 1 1 1 1 1 1 i i i i i i I i I I i I i i i 1 i i i l i |21 LO fll I 1 1 1 1 i 1 l I 12 HISTOLOGICAL. CONFIRMATION Yea Yea 11 14 1 16 1 16 f ESTIMATED | OTHER t OIDhK EXPOSURE t OCCll PAT 1 UN | CAREER l COMMENTS LEVEL | HIGHLIGHTS 1 11 1 1 H1k*> |Autoc L ea ne r | Dri1ler In a 111 yra | f oundry 1 ptlepat Ic teal a |In Oct 1974 me-i96a Id yt*) expoaed to|Polyworker | Fa raer l we re ni*t1. |Ret 1 red 200 ppa 11 yra for fl hr# 1(16 yra) | Feb 1976 | Dork In jtlaea | Hoe pi t al Lsed per day and cerlal nly |1nd. 4 cheat- I Hay 19/6 |caL InHuatry 1 |Coaplet e under JCLtnlcal and 500 ppa |c a ree r del alia In 6 to fare Riven In a 9a1 Ipaper by autoclaveal | Hub let et <i 1 1960-1972 |L n Arch. HelR. expoaed to| 60-200 ppa| B Lira per day In 26a* J Med. Soc. . THyfl. Metf. |Trav. Med. 1 letl 11977 pages autoc1aveaj 1972-1974 expoaed to| 60-200 ppai| 1601-622 1 1 | 1n autocLave rooaj 1974-100 1 * 1 PP* 1975- 60 PP" RETIRED 1 Feb 19761 1 1 1 1 t | Ofl.62-03. 61 01.67 -10.7 I > 200 ppa 6h/da y 04.61-12. 66 * 200 |Autocleaner 1Flreaan at are 1 6 yra 6 at Lia 110 71 . (Operatnr | 1 yra 9at ha. 1 flat a 1xn Inly | 79 : Ttom <* ic ip*It. 07.79. tttepat Ic ( eal a | a 11 ernl III./1. |PoaH1vr |e< lingrapby HP 111.79. Hep*11 e< l nay 07 .Mil. JChenot tie l -tpy . | L fi t or ran ( nn | H I v t-ji Ik | I ft l e l I 7 ->v | 1 9H4 f i un Hr | lie S I L.i.vt i . i i ANAHA Sheet | it I UIPHU.AIS . Klll.YMEKS t.KUIIP I.1VKK AiirI usamiRs CaAeH - (Review hat**: I lari L9H7) All il ri l e s nsr n*. s y -s i t HAY - MONTH - 4- AK WHX/ASI. - I ANl I Ol ASP S , ) I OIINLHY AND REEF HEN! t NO NAME OH INITIALS DATE OF RJRTH FIRST VC EXPOSURE DATE OF DIAGNOSIS ACE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS OF EXPOSURt DATE OF DEATH HISTOLOGIC AL CONFIRMATION ESTIMATED EXPOSURE LEVEL OLCOKA1 I ON OTOE R lAKKKH HIGHLIGHTS OTHER COHMI N I S I3.I2.IT SHAW1N1CAH 26.08.19 1944 1943 19)7 1962 01.09.55 21.12.37 Reactor cleaner X Operator polywerlaatIon Halnt enance 11lwrIght, pipe!liter Operator Worked overtla Saoker X Opera!or, Coreaan Worked overtlae Non-eaoke r 15.12.19 19.07.21 1967 1944 I960 1947 1971 1972 1971 37 51 05 05.07.68 21 10.04.7 J 25 24.12.72 Reactor cleaner Reactor c leaner Operet or, foreaan, wat er coolL hr unit X Mu rfced overtlae Saioker Water cooling unit Worked over!lae Sauker Reactor cleaner Ka l nt eria m e, lllvrIght Worked ove rt Ine Saoker React or rleaner Machine nhop operator and poly unit Worked overl1e Saoker Reartor c Leaner Ma I nt eoance aachine simp 1 (i pi ant 2 5 ytal Saul*. Eu mat e op. pi pel liter aa l nt ena i*t e Worked iivn ( Inc Sank ei * I'tpt-r f*y In |- DPI.iH HI- In Anoalea <1 * Ana t uni e patholoRlque Karla, 197H Vol 21 No 2 ppl03-.ll 4 clalaa this ipe'e had both a hepatoaa and ASL *1 mol I aneoua ly. CMA 006490 CMrt 0 0 6 4 9 1 Vane } CANADA Sheet 2 COUNTRY AND REFERENCE NO NAME OR INITIALS DATE OF Al NTH Cl CHEMICALS & POLYMERS GROUP LIVER Angiosarcoma Cases - (Heview bate: I Jan 19HJ) DAY - MONTH - TEAK All dates use UK system UPK/ASI - LANG luCAST S . H FI AST VC EXPOSURE DATE OF DIAGNOSIS AGE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS TEARS OF EXPOSURE DATE OF DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS 1951 1976 n 00.04.77 React or cleaner Furnace op. a 1 nt enance pack eg l ng X Pane 4 I'ZKCHUSI OVA* I A H I I IIKHKAIS f, POLYMERS CMDltP LIVER Anglosarcoaa Cases - (Review Date: I Jan EM WPX/ASL - l.ANC UH.ASES , 4 COUNTRY AND REFERENCE NO NAHE DR INITIALS DATE OF BIRTH CZECHOSLO- 2fl.06.28 oi.uj.?; FIRST VC EXPOSURE DATE OF DIAGNOSES ACE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS OF EXPOSURE DATE OF DEATH H L STDLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS DTlIt H [JMHI N I S Novaky 01.07.S7 24.12.7) 4S J6 Auloclave Cleaner 1ARC letter of J-4-02 giving det alI f roa Prof A DavId of Centre Ind Hygiene and Occ d L seases. Novaky J1 26.11.6* Au t oclav Cleaner 1 ARC let t er of 1-4-02 gave aoaevhat altered dates for this case. I have accepted the changes since the dates cuae froa Prof A David of the Centre of Indust r La) Hygiene and DccupatIonal Diseases. My dates cuae orlglnajI y froa NIOSH. _L n 3: > o o O' 0 tO # Page U l CHEMICALS 6 POLYMERS GROUP upx/asl - i.AHt.iocAsf s, m FKANO Site el I LIVER Angloeanoma Canes - (Review Date: J Jan B7) 1 i2 1 13 1 4 15 6 ft 1 11 i 1 9 in 1 1 >7 1 11 1 14 1 15 1 16 i1 1 _L _L 1 l1 1 1 COUNTRY AND | KUO HENCE | 1 NAME Oft | INITIALS | DATE OF BIRTH COMPANY 1 1 | FACTORY FIRST VC DATE OF exposuRe i DIAGNOSIS AGE AT DIAGNOSIS YEARS OF EXPOSURE TO 1 YEARS Of l DATE Of EXP0SURE | DEATH 11 1 HISTOLOGICAL | ESTIHATHI 1 | CONFIRMATION | EX POSIIRE | OCCUPATION | OTHER CAREFH | OTIIPK | UlMHPNls NO 1 1 t 1 1i Ji DIAGNOSIS 1 1 1 LEVEL * l1 | HHIHUCHTS 1 l* FRANCE 1 1 1 l 1 1 1 11 1 l 1 11 1 1 01 | H 1 115.04.24 1 AP |ftouaa~ | 11 Ion 00.01.46 i 16.02.67 43 21 1 19 |19.02.67 t Yea 11 | High |Autoclave 1 1 {worker and 1 |Ret. Ravier el | a 1 Arch. Ms . 11 1i i 1 1 |c leaner 1 |Prof. | 10 n` l1 1i l 1 |19 yra 1 11 Nov 75 1l ii i 1 11 1 Ip 171-177 1J Ji i J L1 1 1 1i \ 1 11 1 I 02 f SIH 101.06.11 i PC UK |Irignoud 06.07.59 15.01.75 61 16 12 124.01.75 Yea | High |2 yra on | Italian IRef . 11 1 1 (NIOSH no | laonoaer |orlgln |C Bonnet on et 11 1 1 consent) J 110 yra on 1 |al ~Nonvelle \1 1 1 1 Ipol jmer- 1 1pteaae 11 1 1 1 |laatIon 1 Inedlcale" 11 1 \ 11 1 15 Nov 1977 1i J 1 11 1 IP Mi 1J J J 11 f _________ 11 \ 11 0) |NAV 106.01.20 HP |St Pone 00.00.46 15.01.75 55 29 29 129.06.75 Yea | High |Polyworker |VCH product IonJRef. Rety et 11 1 1 MO jrri aa | 16 yra | al An. h. Ma 1. i1 1 1 1 |autoclave I Italian PDW 1 Prof. | 37 n' 11 1 1 1 |cleaner | Shepherd. |6 June 7? 11 1 1 1 | Confound l ng |Sawyer, Mason Ip 551-555 11 11 1 J____________ 1 1 13 yr. 1 ; 1 1\ 11 1 1 11 1 04 | NOR (27.01.27 PClilt iBrlgnood 19.10.49 16.01.76 49 26 26 104.01.76 Yea | High | Non oner 1 i 11 1 1 1 |product Ion 1 i 11 1 1 1 |worker 1 i 11 11 11 1 1 1 1 1 18 r. 1 i 1 1 |PVC 1 i 1 1 |t M trat Ion 1 i 11 11 1 1 1 1 118 yr. 1 1 1 1t 1 1 OS |B 129.01.36 FCUK tBrlgnoud 16.01.65 11.05.76 36 11 1 II 113.03.76 Yea 11 1 | High |Poly worker ||)Thoracnt oay |Ref. P Loudece 11 l 1 1 Ml yra |9(h Feb 1976 |et al "Seeslne l1 1 1 11 Jrostal Idea huspltsuH 11 1 1 1l |angl uiarcoM |10 Septeabte O1 3: 1 >1 l l 1 1 1 1 1 1 1 1J 11 12)Sc1ntigraphy 1976 11 11 Mound ASL. IPxevIouely had 1 11 11 |3)Haemorrhage | bone l l1 i1 |liua ASL J a ng 1 iiutn !* oi o* O'. * Jg l l l 1 1 1 1 1 1i 1 11 11 14) HI gh t 1 Also 1J 1\ 11 |Hepater t imy | P1J 1 < Nowak l e I 1 1l t1 1 | a J La Nouv 1 1 * 1 ll 11 1 | Pr eaae Medl ihI- <1 \ il 1I i i 1 w-- _iL Ji______ l l _____________L i j___________ 4 j *7th July It 7^ ll'age MRS K*)<** 6 HMNt V SlM'fl 2 111 CIDMI1AES A POI.YMHCS GROUP l-IVER An* I on a n oma Ca&ieH - (Review Dale: I Ian I9B7) ui x/asi - langioi asks , LOHN1KY AND HEhFHENCE NO NAME OR INITIALS DATE OF BIRTH hRANGE 06 07 00 1 1 1 P 1 1 1 1 1 \ 1 1 1 l 1 |C1R 1 1 1 1 ! 1 |B 1 1 1 1 1 ! 1\ 11 1 u.ru 34 J POIK 11 11 1\ 1\ \1 11 1l 1\ 11 11 I1 126.04 27 | RP 11 11 11 11 1 lI |0 L 04.34 | SoJvgy 1i 11 11 11 11 !1 o 3: > o o O''O a FIRST VC EXPOSURE DATE OP DIAGNOSIS AGE AT DIAGNOSIS YEARS OE EXPOSURE TO DIAGNOSIS YEARS OP EXPOSURE DATE OF DEATH HISTOLOCJCAl CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCOPA fI ON ortiKH CAREER HIGHLIGHTS oriiKH GOMhENT') 11 i J 1 11 i 1 1 | Rr tgnoud 101.03.30 1 12.00.76 1 42 | 1i 1 1 1 1i 1 1 1 11 1 1 1 11 i1 11 11 1\ 11 1 1 \ \ \ t 1 1 1 1 \ 1 1 J _1 1 I1 |St Auban 01.07 30 i After 1 49 1 1 1 1 t 1 l 1 1 death \ 1 \ NIOSH i 1 \ eeye 1 1i 1 00.07.76 i ! 1 (Teveux ___ L j___ ____ ____ 1\ 1 1 23.05.57 | 03.12.75 1 42 i1 1 i 11 t 1 11 1 1 \1 1 1\ 1| 11 1 J__ ____ I0.Q1.4B 16 26 19 1 11 i 11 11 11 1 1 1 1 13 IJ1.09.76 | Yea | Moderate M ma-mo) 1 (This man had 1 |(NIOSH | 1 12 yra 1 |A0L prior to J |aaya I 1 | fi11rat Ion l (AS. Ann. de i |I2.09.?6>| 1 110-11 yra 1 | Hal. Pro! 1 11 1 11 1 11 1 11 1 11 1 11 1 | potyworker 1 1 Iland worka f | lab? 1 11 1 11 1 11 1 |July * 1J 4|p 646 6. |A0L was found tin 197 J 1 Ive |yra before | ASL 1 -JJ 1 11 1 _J 1 J ___1____________ 1 1 22 102.07 76 | Yea High IPIant fore- 11972-6 admin IDIert ul 1 \ I {NIOSH no Irnan In laectlon In (septIraemla 1 1 J comment) |polymer- | St Auhan |Small liver 1 11 |laatIon 1 | leal on f uuod \ 1i 11 (after autopay 1 _J________ i 1 11 __L 1 j 1 J 1 ____________________ 1 19 \30.01 77 | Yea | Modera t e |6 yra packer| |Had been \ 11 1 |6 autoclave | 11 unne1 worker 1 11 1 (clnr | |prevloualy 1 11 l 11* yra | 1 \ 1l 1 (autoclave | 1 1 \1 1 (worker | 1 1 _J_____ 1 l _ji ______i____________________ 25.12.77 Very High 194B-I966 Leaser Eapoau re 1966-1976 PolymerIaatIon operator t aut ocleantrt aut ocIave alotenanre 10 yrt* In |Operated 4./* sulphuric | (or removal nt acid factory, | turnout (rum storekeeper A |liver and general |d l ed alter servlies | second | a u rg 11 a I |operat I mi I n |6I Mo | h r<ii li J < I 11 I siula lPaper hy | llr Hel y el -* | l II A It ti 1 ve-> | Ma I Hil-t'H | Pr ol ..................I | Vi> 1 40 N<> O ||9/9 pay. - 1/41 i. j__________ I Cl ('HPMI CAI.S A Pf>| YHKKS CROUP UPX/ASI. - 1 ANOlOLAStS, I t FKANIK Sheet J LEVER Anglosaruma Cades - (Review Male; I .Jan 1987) 1 l1 12 | 11 1 t1 11 ( iHIHTHr AND | NAME OR | DATE OF 1 KFF'K HENCE | INITIALS | BERTH 1 NO 1 l1 P(A<II 1 1 1 \ \ 1 * COMPANY 1 |S 1 61 J 7J 6 1 J1 1 1 | FACTORY FIRST VC 1 DATE OP ACE AT EXPOSURE DIAGNOSIS 1 DIAGNOSIS 1i it i i 9 YEARS OK EXPOSURE TO DIAGNOSIS 11 10 1 1 1 11 11 12 | n 4 1* 1 11 1 YEARS OF | DATE OP EXPOSURE | DEATH 1 11 HISTOLOGICAL | ESTIHATH 0 1 | CONFIRMATION | EXPOSURE | OCCUPATION | 1 LEVEL 1 | J 1[ 1 i1 1 11 is OCHER CAJthtK HIGHLIGHTS 1 | | i lb OTIlfr H C.OMMENiS 111 1VP 1 1 1 1 1 1 |L 1 l 1 1 1 1 1 1 1 1 1 1 1 1 1 1 12 1 1 V 1 i 11 1 \ 1 1 1 1 1 1 1 1 1 1* | HJ \ 1 1 I 1 | 24.05*19 HP 1 St Pom oo,ii.it 10.0I.7S S8 21 1 1i 1 it 1 1i 1 1i 1 | IS.02.12 1 RF \i 1 St Pont i 00.01.41 i 11.08.18 66 37 ! 1i 1\ 1 1i 11 J1 1i 1 1 1i i1 i 11 1I 1I 11 1 11 11 1 1i 1i 116.08,1* PCUR i | Ir lgnood 09.02.49 i 00.OS.79 1 6S 30 11 11 11 ii (19.01.11 Solvty i JTavaua ii I 21.01.41 24.04.19 *0 i 16 1 41 1 1\ t1 11 t1 l1 11 t1 11 1I 1 |0S-0*-2* Ch loe |St Fone 1 1 Chlale 1 1 1 { Ko raerJ y 1 1 1 RP) t 11 1 i t i i i I 19*3 i 00.01.*! 38 11 11 11 11 i I 21 |10.01.78 1 1 1 1 \ 31 M3.11.76 1 1 1 1 1 1 1 1 1 11 1 1 1 1 1 E 1 27 123.06.79 \ 1 1 i1 13 122.08.>9 1 1 1 1 1 1 1 1 1 1 36 129.01.81 1 1 1 1 1 1 J Yea Yea Yea Yea Tea | High |Aut oclave |10 yra In (Died of 1 !cleaner Jaechant cal |pulawnary 11 |engl nee ring feabollaa S 11 11 11 nduat ry (19A6-I9S6 (days alter |aurgery 1 | High 1 1 1 1 1 1 1 1 1 1 1 1 1 t 1 1 1 |19*1-19*6 | poljraer| laatIon Igeneral |purpoae |worker 1 |19*6-1972 1 VCH laynlheala |(HCI 4 |Acetylene) J Foreaan 1(agent |de altrlae)| 11972 |retlred 1 i Lj | High | Mo novae r j 1 (product Ion 1 (and polyaer- 1 | laatIon i loperator j | | Autocleaner |2 yra aa rye lei Clgarette 1 11 r.. jaechanlv. |aaoker mit 1 1 1 (Auto- MO yra aa | 197*. Ml i*M 1 (operator leriaaej 1 er In |of 1977 due 1 |9 yia, Jaanltary ware | Oeauphagr.il 1 |Cupolyaera J aamjf art ore |va r1 rex. 1 1* yr. | Su rg 1 r a 1 11 | Ini ei vcn< 1 <n 11 I2S.US.19 11 1 ( r 1 gt. t 11 | Very High 119*3-197S 119)5-19)9 | hepa l ri 1 i>my ) 1 19* 3-197S (All typea ol |aa1ntenanre 1 a nd IJoba on f work 1 Enteral it - | aanufarture * ent ly ft aalntenarir e 1 I97S-1979 |In VCH Poly 1 |Pioceaa CMA 0 0 6 4 9 u IJ*P r MAM h Mil'll 4 LIVER AnglnHarcuna Canes - (Review Dale: I Jan 1967) WPX/ A1- ANl 11:H ASt 'n ^ h I 1 12 i ii 1 1 i oiihTHY ANN | J i NAME OR J DATE OF REFERENCE | INITIALS | BIRTH NO ( 1 f i am e ( 1 1 J 1 1 4 COMPANY 1 |5 6 ! 1 1 | FACTORY FIRST VC EXPOSURE 1 1 1i 1 7 DATE OF DIAGNOSIS ft 1 9 10 1 11 ACE AT YEARS OF 1 J YEARS OF| DATE OF DIAGNOSIS |EXPOSURE TO|EXPOSURE! DEATH DIAGNOSIS 1 1 i I 1 12 1 1 1 HISTOLOGICAL | CONFIRMATION | 1 1 11 | 1 1 FST1MATED | EXPOSURE ( LEVEJ | 14 OCCUPATION 1 1 | | 11 1i 11 15 OTHhK CAREER HlMh U.HTS 1 1 OTHM l coMMhN rs j | l.el t Hepflt e< Icviy | 1961 IS | DEP 1 1 1 1 1 J 1 16 J GIN 1 1 1 1 1 101.01.17 Chloe 1 Chlate 1 (formerly 1 RP) 1 1 JX 1 111.07.27 Chloe 1 Chlale 1 (Po raerly 1 tp) \ 1 |St i 1 1 1 1 1 1 |St i \ 1 1 1 Poor Font 07.07.55 28.09.02 i j I7.t0.41 05.01.SI i 45 27 27 |Alive 1 1 1 1 1 i i1 1 61 41 10 101.04.SI 1 1 1 t 1 Yea Yea |ttlgh-2U yr (Autoclave (Moderate (cleaner 1? yr. II959-I962 | (autoclave 1 (operator 1 |1962-1902 ; J1 11 (Hlgh-11 yrs|Polyveriaat- (Moderate- |ion Proceaa I Low - 5 yra|Han 11 1 (Maintenance | (Worker |J C Contaseot (Letter of (5 10 1961 | l 1 ( |Ret Lred Man 1979. M C Contaaaot | I.W tera ol 15 10 1961 and 125 7 64. 7 16 n 3: > o o j* <i O' 1 1 1 \ (HAR 1 1 i j i I I i * I ir i j i t i i i i i i i i i i i 11 1l 1 1 |22*07.21 chio* \ J |St Fona 1 CMale 1 1 (Foraerljr 1 1 W) 1 11 11 11 11 11 1 1 IH.07.42 Solway 1 1 | Tavaux (1 11 1( 11 1( 11 11 11 1J 11 fJ 11 11 11 1 i1 1 ! 1 7.06.AS 03.04.01 09.09.61 2I.01.S4 1 60 42 i 14 21 f 1 i1 1 26 103.04.03 1 i 1 1 1 1 1 1 2J 127.12.04 ( \ ( t 1 1 1 1 1 11 11 11 11 1 __i _L 1 (Health 6 1 |Safety Agent| ( Yea J_________ 1 (High |21 yrs 1 t 1 1 t 1 1 1 1 |Autoclave (Cleaner |1946-197( 1 1 1 1 1 I 1 (Other aertora (of St Pooh (Factory 197111970 1 1 | Ret 1 reil (01.01.79 | 1 C Coniaasnt | Let t er of (5 10 1961 * Jf 1t 71.01.04 |Hlgh-J 2 yre|Autoctave (Lou - 9 yraJCleaner 11 11 11 11 1! 11 11 11 11 11 11 (1 11 11 109.01.64 might |Nepalectuay 105.05.64(24.09.64 (chewot herapy |tor lung| ae t a* t J a (pailLai 11eelea tun. 106.64 - lluri | r er u i i-m e. (lit.64 - 1 ii I!,*: (evolut Idii ol 11 he (I l Mr Aise ( P.ljec 9 FHANf F Sheet *1 COUNTRY AND REFERENCE NO NAME OH INITIALS DATE OH BIRTH S. 12.12 01.10.40 EC] C11KMI CALS 4 POLYMERS CROUP LIVER Angloaarr Cane* - (Hewleu Date: Jan 1987) CH/V.L - LAttCMH AMS,!* FIRST VC EXPOSURE Rrtgnoud 07.04.59 Irlgnoud 1951 SEP Hontlucon 1959 DATE OF DIAGNOSIS 26.10.84 27.12.85 01.06.06 ACE AT DIAGNOSIS 45 YEARS OH EXPOSURE TO DIAGNOSIS 27 TEARS OF EXPOSURE DATE OF DEATH 22 26.12.85 HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS I | | | O INCH COMMENT S High High High AutocI awe operatur and cleaner |Myocardial 11 nf arc 11 chi | ) 980.Coronar y Ibypaea 1981. |Let ter f roe |Dr Contauaoi |S.4.86 Autoclave -L In other parta|Portal operator and of factory cleaner since 1946 |flbroala Iron 126.04.74. The 11 IIneaa waa Idlagnuaed aa Jpreauaably (work related |on 211.04. 74. |Letter f ron | Dr Contaaum 105.04.86 Autocleaner Ha 1nt enance 4 yeara worker 1 |Nepal 1c teht |Hay 84 ncjiaal . IHepatIc teat I May 86 allowed |a bno raalilies. |Lett er fron | Dr Rarrat 118.07.86. n :x > o o 0- >0 SJ GERMANY She el I COUNTRY AND REFERENCE NO NAME OR INITIALS DATE OF ftIRTH ICE CHkHICAl S A POLYMERS CROUP LIVER Angtoaarcoaa Cases - (Review Dale: I Isn 148/) UPl/ASL - I ANUlm ASPS, 1% | FIRST VC FACTORY | UPOSURE DATE OF DIAGNOSIS ACE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS OF EXPOSURE DATE OF DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS I | | | other CUHMINIh 4 | 01.10.56 19.09.68 _____ I_________ Yea (N10SH) Polyvorker 02 | 14.10.5? 25.09.70 19 Yea (NIOSH) Polyworker _L X 12 12 l 09.06.52 00.03.71 I I 1 l \ I | 16.04.57 21 16 Yea (NIOSH) FI 111 ng (Reported under peatIclde | non polynaer- aerosol cans t L sat Ion with VC Iworkera In | NIOSH list tit 111.1.71. )Thls oi course 11 a strict ly |corre< t. (However I Iwonder (whether this |aan had high (espoaure to IVCH In his lean f I I li ng loperatlonT J___________ I 17 25. II.74 Yea (NIOSH) 200-500 pps Polyworker 6 1958 was (Clinical but high temporary autocleaner |detslla 1 n during I yr autocleaner lor J yr |paper by autocleaner IGokel et a I | VI rchows Ai i It |A Path IV/E 11/2 P I9wm I o 3: :> o o o >0 CO Page U ) CHEMICALS 4 POLYMERS CRUUP WCX/ASI - I.ANl, 1 ()( ASl S , Mi GERMANY Sheet 2 LIVER Angloaarroma Canes - (Review Date; I Jan J98?> 1 11 1 1 COUNTRY AND I REFERENCE J NO | GERMANY 1 1 I 1 71 NAME OR INITIALS 1 1 \ | 1 1 1 1 1 ]1 DATE OF BIRTH 1 1 1 1 1 I 1 1 4 COMPANY 1 15 \ 1 1 1 FACTORY 1 1 1 1 1 11 6 s1 9 1 io 1 1 1 12 FIRST VC IXFOSURE X\ 1 11 1 1 11 DATE OF ACE AT 1 YEARS OF | YEARS OF 1 DATE OF | HISTOLOGICAL 01ACHOSIS DIACHOS S | EXPOSURE TO | EXPOSURE | DEATH | CONFIRMATION 1 D1ACNOSIS 1 11 X ! 1 11 1 1 11 I 1 \1 1 13 1 1 >4 | 11 11 ESTIMATED 1 1 EXPOSURE | OCCUPATION | LEVEL 1 1 11 11 11 15 OTHER CAREER HIGHLIGHTS 1 1 1 ( | OTHhH | COMHhNlS ( 1 1 (Coni 11 med 05 | 1 (NIOSH glves| ai Case 06) I 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 \ 06 t 1 <NIOSH gives 1 a* Case 05) I 1 07 I 1 1 1 1 1 1 1 1 l 1 l OR 1 1 1 1 100.00.36 1 11 11 11 11 11 \1 11 11 *1 11 i1 11 I1 11 11 \1 11 1 1 100.00.32 1 1 1 i 1 1 i 1 1 1 11 100.00.26 1 11 11 1i Ii 1I 1i 1I (i 1i 11 1i 100.00.17 i 1i 1i 1i 1 _L 11 7 t 4 11 1 1 i \ 1 1 1 1 I 1 \ 1 1 1 1 1 1 \ 1 17 1 i 1 | 1 1B 1 1 1 1 1 \ 1 1 l I \ 14 1 1 I _X 02.04.60 10.12.73 i i 1 1 i 1 16.17.62 1 00.00.75 i i 15.04.54 12.11.75 19.07.54 06.04.75 XX X 38 i i I I I i I i I I I 1 I \ t \ I 1 \ 43 I I 1 I I 1 49 I i I i i i i i i I 1 i 58 i i * i ___ L 13 13 21 20 1 05 |16.12.74 |Yea (N(OSH) 1 11 1 11 1 t1 1 t1 1 11 1 11 1 11 1 11 1 11 1 11 1 11 1 11 1 11 1 11 1 11 1 11 1 11 r* 1 i1 1 12 109.01.75 | Yea 1 11 1 11 1 11 l Jf \ 11 1 21 113.M.75 1 MNIOSR 1 1 1 r> il) 1 1 1 i1 1 11 1 i1 1 11 1 11 l 11 i 11 1 J1 1 11 1 20 (25.12.75 | Tea Yea 1 11 1 11 1 11 J JJ X |RC Gieml e | (eays | |"chemistry | 11 aboratorlsn| (In the | (Techno(logical (Research (Department** | | | ( |(NIOSH says | Jasslstant (factory (chemist ( | | (which may be| (wrong | |t rsnslatIon) 1 t 1 1 1 tfVC - MenuIfscture 1 1 1 1 | | | Shift Leader) ii ii 11 IFVC Hanu- | (tacture and | | a11 work | (Incl auto- | (cleaning | 111 T M ]*-> 1 , I Foreman TechJ |Dev 6 yea J 1(1967-1975) ( i i |Polyworker ( i | 1 1 1 J!_ 1 1 1 7 (Repor led nnder |non-pn1yae t |1aatInn (workers In (NIOSH 1 1st at (11.1.77 and (1.78. I don't |t hi nh t li 1 a la (a rorrect |clasllteal inn |by NIOSH. Tlie |man may have | been 1 ovn 1 veil |1n VCH | pu 1 yme r 1 a al 1 >>n | In pi Ini pi am (or 1 u main (pi ant. 1 1 1 1 1 1 1 1 1 1 1 1 l 1 1 1 1 * ! 1 1 1 1 1 1 CMA 0 0 6 4 9 9 PaRe 12 GERMANY Sheet 1 [Cl CHEHI CALS A POLVMLRS GROUP LlVEk'^ngloearroaa Canes - (Review Uste: l Jan (967) WKX/ASl. - LANGlOCAStSJ7 1 J1 1 1 12 i31 A 1 5 6 1 7| 0 1 9 JO | II 11 * 12 1 3 1 14 ( i 1 _L _L _L 1 i 1i i 1 COUNTRY AND | NAME OR | DATE OF i I FIRST VC DATE OF | ACE AT YEARS OF REFERENCE l INITIALS 1 BIRTH i COMPANY i FACTORY UPOSURE DIAGNOSIS | DIAGNOSIS EXPOSURE TO NO | 1i ji 1 DIAGNOSIS 1 l YEARS OP | DATE OP EXPOSURE | DEATH 1 11 1 11 J HISTOLOGICAL 1 ESTIMATED 1 1 CONFIRMATION ( EXPOSURE ( OCCUPATION 1 1 LEVEL 1 1 GERMANY I 1 | J J_ 1i 1f 1I i 1 L 1 1 \ 11 1 11 1 1 11 1 11 1 09 | 100.00.34 i 2 1 2 20.02.61 16.06.76 | 41 15 J 3 124.03.76 Yes |Hlgh peeks I 12 yr poly 1 1 1i I l1 1 1 (worker Incl 1 1 1i Ii 1 1 1 1171 auto- 1 1 1i i 1 1 ( Iclaue 1 1 1i i 1i I Ii t i 1 1 |cLeanlng 1 1 1 |Control roo*| i 1i i l1 ( 1 II yr 1 1 Ji i 1i 1i i 1 1 1 11 1 1 11 1 l io r (NIOSH gives| at Case tl) 1 1 1 J _L 1 (00.00.36 1 1i 1i 1( 1l 2 1 I I2 I 1 I I l 01.01.61 1 00.01.77 | 40 16 1i 1 ti 1i 1 1 10 (07.03.77 1 1 1 1 Yea 1 1 (High 1 1 1 1 peeks J 11 (10 yre poly -1 |worker lncl 1 |171 auto- 1 |cLave 1 (cleaning ( 1 1i I ti i 11 1 1 1( I 1 ii 11 1 1 1l i 1i 1 11 1 11 < NIOSH .. Cut 1 1 1 10)| 1 1 1 J 1 100.00.29 1 1 1 1 1 1 [ i i i i i l _L I e i0 I I I I I i 10.10.55 1 20.06.77 | 47 71 1 1 1 \ 1 1 22 120.06.77 1 1 1 1 1 i| 11 1 Yes 1 High (1 yre auto- 1 1 |clave 1 1 |c leaner 1 1 114 pra 1 1 (filter 1 1 (operetor 1 j 1 12 1 1 1 1 J\ 1 1\ I 100.00.30 i A 1 4 1l I 1i I *( 1 00.00.61 00.(0.77 i I | 1 1 1 39 16 t \ 6 107.10.77 1 1 1 Yea 1i \ 1f 1 1 7 |PVC Menu- 1 1 | facture 1 1 |Autoclave 1 t (worker lor 1 1 1i i 1 1 1 16 yre 1 1 1l i 1 1 11 1 1 1i i 1 1 11 1 i 1i i iJ 11 11 1 1 Oi 3: i >i 1l li 1i 1i i i i j t( 11 1J 11 11 1 Il 1( 11 If I1 1l 1 1 1 J oI l* 1t i i t Lt 1j _L ! _L 11 J1 1 Otn oo IS 1 it* OTHER CAREER HIGHLIGHTS l J ] ! itmm ClMHINIS |I0/7B |Cout 1 rneil |Average |expoeur e first |9 yre ISO p|, lore IIIOII p|*s. | Next 3 yrs n, |75 ppn. Last. |yr ev IS ppsi 1 |Average (exposure 11 ret |9 yrs 150 p|*, (ore 14100 pi*. (Last yr au (75 pym. CWH 11et ter ot I2I.04.7H 1 ( j | | | 1 1 I I 1 i * i i i \ p-* 13 GERMANY Sheet 4 [Cl CHEMICALS E^VER Angluaarcona (ises POLYMERS GROUP (Review Dst e Jen 1987) UPX/ASI. - LANCliK ASF 5, |H 1 COUNTRY AND REFERENCE NO GERMANY 2| 1 NAME OR 1 INITIALS | 1 \ 1 1 DATE OF BIRTH 1 | 1 1 1 | \ 1 4 COMPANY 5 Lf i i 1 8 9 ii FIRST VC | DATE OF 1 FACTORY EXPOSURE | DIAGNOSIS 11 _l ACE AT YEARS OF DIAGNOSIS EXPOSURE TO DIAGNOSIS |1 1 1 10 1 H 1 12 |n i 1 1 5 1 16 11 1 J___________ 1 YEARS OF | DATE OF | HISTOLOGICAL 1 ESTIMATED 1 1 EXPOSURE | DEATH | CONFIRMATION | EXPOSURE | OCCUPATION 1 OTH EX CAKFKX 1 | OTHPR | COHHFNls 11 1 LEVEL 1 HU.HI IGHTS 1 J JL 11 1 j_________________ 1 1 i ...______________ i 11 1 *i 11 14 1 5 < N10SH *lvee| this Caae (1) 16 n 3: > o o O'- 100.00.14 1 11 1i 11 11 11 ii 11 11 11 11 11 11 11 11 11 11 I1 11 11 11 1\ 1( I1 11 1| (00.00.29 i \1 11 1\ (1 I( (1 11 ii 100.00.23 1 t1 11 11 11 1 I 1 l 1 I t 7 8 4 1 _L 7 00.00.60 | 08.04.78 63 1 1\ 1i \ 11 ( ii i | i i i 1i ( l\ 11 11 1\ 1\ 1\ 1\ i 1t (1 11 11 11 11 1\ 1\ 1 1l 1 j \| 18 19.10.53 i 09.io.it 49 1i 11 11 ( *1 11 1 11 ( (1 1 \ ii | i 1i 10.01.55 I o7.oi.th 55 i 11 |( Lei bach 11 |iuipccte4 11 |ASL ftt 11 |Peb J975 11 11 J1eparotony)( 1 11 11 1 1 1 I1 1 11 1 11 1 11 1 l t1 | 11j _L 18 25 23 14 119.05.78 1 Yea | 1 11 11 1 11 11 1 11 11 11 1J 1 1 11 1i 1 i i JL j_________________ i 1 |Hot ftn ( 1 1 i 1 |Angloaarcoaa | 1 1 1 |In hl letter | l 1 1 |of 21 J2 81, | 1 1 1 | Hr Frledel | 1 1 |ftftld thlft Wftft | 1 1 1 | "Plattenepl-| 1 1 1 tthelkarclnoa ( 1 | Der | ( |Spelerohre~ j 1 |(a cftrctnoaft | I (of the | 1 1 1 1 l 1 J 1 1 1 |oesophagus) | 1 |not attribute | 1 (able to VCN 6 | i 1 (not rtcognliedl 1 |aa an tnduat- | i 1 (rial disease | i l JL i 25 123.10.78 1 Yea I \1 i1 1 1 \1 1 11 1 1\ 1 11 1 11 1 11 11 11 11 11 1 j_________________ _L T |Autoclave I |cleaner and i (worker. I |Drier t (operator. i |Later shift i (1eader i II i i JL j_________________ _L 10 107.08.70 l 1 High (Autoclave 1 1 |ASL and I (worker till 1 1 |Hepstotellular 1 1 1964. 1 1 (Carclnoaa | |Leader a nd 1 11 1 1 11 11 1I 1I 11 11 11 11 1 11 11 i1 11 11 11 11 11 11 11 11 11 i j _LL j 1 1 1 I t 1 i 1 1 1 _L | F W Beat 11et ter oi (30th June 1980 |enclosing data | i rn* |Hr H P Frledel |of BC Client e |F V Beat (letter ol |30th June I9RU |enc loal ng data (t run |H P Frtedel of | BC Oieale | wl thdraul ng |thls case 1 1 1 1 I 1 1 1 _J | Angloaarc dm (cunf 1 rued (09/ 79. Sonr (detail of 11 > 1 -u(A alao rain-s 19, n, IS. (6 |6 I 7 g i ven 1 ii |NHW Report lui 1 19 78 | Anglnsarr umu | ( onf 1 reed , (lull dec all*. (of II Int-N-t (aim: c Hrf 11 Ik 119/1 g l wen In |NftW Med tn^p 1 Hep foi (9/h. | lilt 1 e* fill |del < 1 Is R 1 vrii | 1 n VI | Aa him 1 h i *.1 | [>l ae.ii.i- by | I v 1 hdi h .1 ud IHhihIiH.1 i' i 1 1** GERMANY Sheet 5 COUNTRY AMD REFERENCE NO NAME OR INITIALS DATE OF BIRTH COMPANY U.I CHhMICAiS & POLYMERS GROUP LIVER Angluaarrou - (Review Date: I Jan |9BJ) UPX/ASI. - LANG lOCASt1,, | V FIRST VC UFOSURE DATE OF DIAGNOSIS ACE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS OF EXPOSURE DATE OF DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS I I | | | OI ID K COMHI-NES 1? (NIOSH gives as Case IS) 00.00.37 | 4 4 01*11.SI 14.0R.7S 41 16 LJ 2S.OR.78 Yes 111!1!111111L ia 1 ioo.no.n 1 5 1 5 1 00.00.55 1 15.12.79 | 66 i it i 21 125.12.79 1 Tea | 1 i1 11 1 1 1 11 1 1 19 \ 1 1 JL 100.00.25 1 4 1 4 i IB.10.it | 00.OR.79 | s! i 25 I \1 1 1R III.01.BO 1 Yea 1 | 1 11 11 1 1 \ 1 INetaataalng | 1 11 1i 1 1 i i 1 1ASL | 1 \1 11 1 1 1 1\ 1 J 20 1 \ 1\ [I 1 1 100.00.15 1 4 J 4 1 U.01.61 I OO.Ot.BO1 65 ii 1i 1 1 1\ 1 n19 \ |19.10.to 1 Tea | 1 1 IKacMnglo | i 11 11 \ 1 1 11 11 t 1 1 11 1l 1 1 J _J_______ 1 J__ r f 1 1 1 21 1 100.00.13 1 4 i 4 1 01.01.62 | 00.09.79 | 66 1 1R 1 11 l 1i \1 i1 |pronounced | Icllnlcal | 1 1l 1 1l i1 i1 (liver l.yat M ) | | 1 \ lEndothelloaa f 1 i |of liver with | 1 J (Metaataaea | \ ii i 1 13 |19.06.60 1 Yea | 1 1 IHaeaianglo | 1 1 |Endothelloe | 1 ( |of liver with | 11 1 !? 1 1l \1 I IB.OS.SO I" ___ ____ ino.tio.il l 4 i 4 1 15,1*1.61 59 1 19 |1 M jot.1?.11 J1________KLi 1 I 1l 1 1l i1 i1 1 1 1 1 1 1 (Metaataalng | 1, 1 | ASL | High High High High High Autor I ave worker No _1 |Autoclave (Worker 1 1 1 |Autoclave 1 1 (Worker 1 11 11 (Autoclave |Worker * 1 1 1( 1( 11 \ | Autoclave |Uorker and Iworked In |d tying shop \ \ J 1 t 11 (Aiitor lave 1 (Chargehaitd, (Worker | Subseluent 1 y 1 | Fo reaari (Anglos art uad (conf I need. |Annual report |of the North I Ah I ne lUeatphalla (HediesI | Inspectorate (for mu Ipagea 147- \) t (gives fnl J |det al la. Vinyl |chloride |dlaeaae |d lag nosed (02-02-71. |Oesophageal (varices. | Rail L ol ng I i a l I y (coni 1 raed di i u lo.teoly.il,. | J | Dr Beeclie 11et ter ol |13-04-82 m | Dr U 0 E Ad.uiy 1 |Dr Besrhe (letter ol (13-04-82 m | Ur W L h Adda* t ( |0r Best-he (letter ol ||1-04-82 lo | Dr W (, h Ad.... i j Dr Be r>< Fie 11 el t et <>t |I 1-04-87 1 ' CMA 0 0 6 5 0 2 Page 15 GERMANY Sheet 6 Itl CHEMICALS t, POLYMERS GROUP LIVES Angl naarrnna Cases ( Sew Date: l Jan 19HJ) UPX/Abl. - LANt.HK ASKS ,/U COUNTRY AND REFERENCE NO NAME OR INITIALS DATE OF BIRTH GERMANY 21 | | 1 1 1 1 1 1 11 100.00.27 | 11 11 t1 11 11 !! 00.00.26 00.00.21 00.00.22 26 21.11.31 00.00.17 o i a8 _J_ 12 HISTO FIRST VC EXPOSURE DATE OF DIAGNOSIS ACE AT | YEARS OF DIAGNOSIS 1 EXPOSURE TO | DIAGNOSIS YEARS OF EXPOSURE DATE OF DEATH LOGICAL CONFIRM ATION ESTIMATED EXPOSURE LEVEL OCCUPATION I i | 1955 i1 | 26.01.79 1 51 1 111 i i 24 1 21 |29.09.61 1 Yea | High IChemlatry | 11 1 1 1 t i >J00 pp.) (Worker | 11 1 1 111 J I 11 1 1 111 t 1 11 1 t 111 1 1 11 1 \ 111 1 1 1669 J___ ____ ,________1 11.10.62 I) 1 1 26.05.61 L !L High Autoclave (*300 ppm) Cleaner 1555" i4.a4.ti ~W 21 TT U.oi.ei 1951 14.06.76 TT 22 22 12.11.81 High High Polyclave Uurker and Autoclave Cleaner Polyworfcer 1955 16.01.61 "TT 01.10.io 11.06.65 61 "TT 25 ir 02.01.64 25 15.06.85 High High Autoclave Cl eaner till 1972 Procesa worker 194764 (01.10.60 -11.01.64 PVC product ion. agitator area). OTHER CARFFK HIGHLIGHTS | i 1 OTHER COMMENTS j IPrlmary hepatoielIni tcarclnoma; proliferation of the lalnusludal cells with |a 1nuaoldat ertaafa. iFrkede) letter 21.l2.6h. 1 I Prof Eder {Munich) lletter 22*06.63. IFHedel letter 19.04.65. I Prof Selmalr {Munich) II el ter 22.06.6). |Frledel teller 19.04.H5 I |Chronic hep at It la . I angl omat nils , sinusoidal fectaala. Krledel letter I 2).I 2.66. J l^lbarh. (Frledet tetter (19.04.65 _L (Annual VCM arreenlng 124,04.65; no coup I-fine, too abnormality deteMed. |1970 two-Chlrda Igaat rertomy fur ulieis. |1971 Coronary t In ambusIs I 1961 Femora I |imp!antatIon 11964 Pulmonary embolism land j>l eurnpiieomonl <. I Lander a letters IH.ifJ.liS land 04.02.67. 15.02.61 15.02.64 High Cheml at ry worker l Haenangj os a r ko,i. IFrleileJ U-ttei /i.i.'.m,. 1951 07.01.60 10.06.65 00.04,65 25 25.05.61 12 21 |AIlv e Polyworker Sill ft leader Autor I awe cleaner Polyuorker Aot ih lave { I eri ne r I Haemang t ottai k dim . tFrledel letter .M.I.'.Mt). I | Haema ng lobar k mid . | Fr I edel letter .MJ | Haemo og j m ,li Lm . If i leLlel litl.-i J l. I'. CMA 0 0 6 5 Page 16 t TAI.V 11 l l ll>HI ( Al S lJOI Thh K-S (.KOMI' LIVER Anglosarcoae Cauea - (Review Hale: I Ian |98J) WI'X/ASP, - 1 A Mi. Km Ast s 1 l1 J 1 COUNTRY AND J RFFERENCE | NO 1 1 ITALY 1 l 2 NAME 1 J 1 OR | 1 DATE OF INITIALS 1 BIRTH P 1 J _L 1 4 COMPANY 1 1 ^ ~^7 15 61 7 8 11 11 1 1 FIRST VC | DATE OF ACE AT i factory i EXPOSURE | DIAGNOSIS | DIAGNOSIS L i Pi 9 1 ID i i !! 11 YEARS OF I YEARS OF | DATE OF EXPOSURE TO | EXPOSURE | DEATH DIAGNOSES I 1 f1 Pi 12 1 11 1 P4 1 15 1 lh HISTOLOGICAL | CONFIRMATION | ESTIMATED ! EXPOSURE | LEVEL 1 1 OCCUPATION | | | P OTHER CAREER HIGHLIGHTS | ( oniHt U WHEN IS 01 (On NIOSH Siippl eaentary Hat) 0? 01 04 1 u: \ 1 p \ 1 1 1 1 | SE 1 P 1 (VC 1 p 1 1 J 1 |FI 1 1 1 ! 1 1 1 1 1 1 (15.06.34 PANSAC IHlri | 00.00.65 | I9.04.7P 1 (Venice p 1 PP 1 ( P1 ii 11 1 1 j______________ 1 11 |11.1J.29 HontediaonjPorto | 00.00.57 | 13.12. 72 1 J 1 114.03.20 Solvay (Harghera J______________l 11 (Ferrara | 00.01.61 | 10.07.75 1 P1 1 1P 1 pr P ii j j. \ 120.07.17 ANfC j______________ ii |Ravenna \ 00.04.59 | 00.01.81 1 IJ 1 1( 1 ii 1 JP ! 1J 1 11 1 P1 P 11 1 11 1 P1 16 06 43 55 15 22 43 21 i I 03 116.04.71 P1 I1 p1 I1 l1 iP 1i lp I 06 127.12.72 l1 11 lP P 21 |IQ.07.75 I! l1 p1 p1 i ii lP 1 21 110.01.8 L iP i1 lP l1 i1 l1 p1 PP i 11 i P( ?Yea Yea Yea Yea | IfVC H.g leatruder | 1 P | ii | Pi laa i y t iNuit r |aay have Pjem | perl carillua. |Not PiuaoJgenetma with Jot lie r cases. 1 * a* | | High |Polyworker ii P |Autocleaner | |8 yre (1951- | |6i) Autoclave loperator J P12 yra (196 1*2) i 1* 1 1972-6 did a variety op| Jobe tncl tiding * PVC packing a* ** | 12 yra - PI yr - |Never cleaned Very High |Honoae r loperator |autoc1svee. |See paper by * a* 5 yra - | ICHIAFPINO et |Non-aaok e r. Hedlua p 20 yra - |al Med Lavoro |Conauaed JAutoclave I Vo1 6 (I982> I l Itt le 4 yra - (operator 6 |pp 555-561 (alt oliol. Mu Low (other duties PAUL. |in euspene- (Ion polyaer- 11aetIon. l1 tt 11 11 11 t1 11 11 11 11 n5 |C Danes!n | 19.01.17 PANSAC IHire | 00.00.67 | 07.01.81 11 |Venice j 11 11 11 11 11 1I 1 P _L P <1 iP iI 1P i1 46 16 i a 106.04.81 1 i 11 i 11 p 11 i 11 X __L _i_ | Yea 1 (Heditaa-? IHifth (Area ForeaanJ |in aaae Dept Pelnce 1975. 1 | Rag eat ruder 1I967-J976 |CuaaerrPal IGept 1976| 1981 1 | S I'ag II a (P.ouga lelr* ut | 2 Aug 1VH 1 * See Hal 1<><il Heil d! Lavuvo AS p44S , 1974 . Further detaPla In etter fro* Dr Hunt esann u f 1 ARC on April Pat 1902. * Also aee Hal tool and RondlnePla In Arts Onco log!ca Vo1 P98G pagea 15 - 49 Pa#** 17 lAPAN ill (tit HI CALS 6 puLtHHiS i, mm I-1 LIVER Angloairroan Case** - (Review Date; I Jan I9RJ) \ 11 >WFX/AM AM tH ASt s 12 |11 4 |5 \1 COUNTRY AND | REFERENCE | NO JAPAN i 1 NAME ON J INITIAL'S 1 DATE OF BIRTH | COMPANY | FACTORY i 01 | Tcmso] 1 101.08.22 tHltaul (Nagoya | hurl Itoatsu 1 |(no consent (by Jap PVC 1 |Aaaoc) 1 1 1 1 1 412 ISO 1 l i 102.08.19 j_____________ j________________ 6 FIRST VC EXPOSURE 00.04.51 00.11.58 ? DATE OF DIAGNOSIS * 24.10.75 10.00.76 6 9 10 1 AGE AT DIAGNOSIS YEANS OF EXPOSURE TO DIAGNOSES YEANS OF EXPOSURE DATE OF DEATH _______ aa 53 22 n 24,10.75 _______ 37 17 13 10.00.76 .1 j_______________ 1 ? 1 * l *4 1 11 HISTOLOGICAL | ESTIMATED 1 CONFIKMATION | EXPOSURE | OCCtPATION | LEVEL 1 11 11 1 Yea 11 | PVC Aaaoc ||3 yrs auto- Isays not |c lave (known. |cleaner |* Japan 11964 - (Tfaea (assigned to |1ndlcsted |dlf ferent |on 25.10*75|work since (exposures |had 111 |often at (lieal th (3000 ppn up| |to 1974 1 J1 1 Yes (Not known |In polyner- 1 |Isat(on work | | (nclttd Ing | (autoclave |c leaning i j__________________ 5 orutK CAHI-KK HIGHLIGHTS 1 1 16 1 1 i nrum 1 roHhiNis l 1 4 1 1 | JapHii T | 25. HI. 1 5 k | Papajieue PVC | As am 1 ett et lot ll.tti./H 1 1 1 1 1 1 1 1 | lapaneae PVt |AshociaiInn | 1 et ter nl |11.01./H 1 * In hU letter of let April 1982, Dr Hantesano of IAJIC says Japanese Ministry of Labour give Date of diagnosis - 21-00-74 Age of diagnosis - 52 Years of empoatire - 22 CMA 0 0 6 5 0 tn '`H1' 1 NORWAY 1. IVEK Anglos an. uaa Cased - (Review Date: ] Jan WHK/ASL - I.AM.hJi'A-.t-.,/ I COUNTRY AND REFERENCE NO name OR INITIALS DATE Of RIATH FIRST VC EXPOSURE DATE OP DIAGNOSIS AGE AT DIAGNOSIS YEARS OP EXPOSURE TO DIAGNOSIS YEARS OP EXPOSURE DATE OF DEATH HISTOLOGICAL CONFIRMATION FST I MATED EXPOSURE LEVEL OCCUPA TI ON OTHER CAREEN HIGHLIGHTS oriOH 1 ilMHPNI S 21.12.IS Norik Hydro Heroya 00.01.so 21.12.71 High Foreman 4 Aut oclave aupervlaor Coni I rmed by Dr ThlIsEvflnaen ul Nil. Ac APMK htK "I 9 June Hr P Kangne* ataled tlamC All had been h member ok a tart -up t ram . VCM 4 PVI. ware mad e I n b amtbuilding. Hie VCH was mdde f rum dt cl ylt-ne CMA 0 0 6 5 0 6 Page 19 SUtOEN ILL CHEMH.ALS 6 POLYMtKS l.KOUP l.IVER AngloianaM Cases - (Review Date: 1 fan 1967) WPX/AS1 - I.ANCIOiAbtS,2'. COUNTRY AND REFERENCE NO NAHE OR INITIALS DATE Or siR-m FIRST VC UPOSURE DATE OF DIAGNOSIS ACE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS OF EXPOSURE DATE OF DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHI-K CAREER HIGHLIGHTS <i mm COHMtNI S 21.06.2? 02 27.LI.il 14.OS.51 20.10.70 00.01.45 00.05.47 16.03.76 L2.05.77 22.11.60 19 27 27 29 19.03.76 22,lI.60 Hlfth Poljrwo rker VCH product Ion High High Polyworker 1946-1950 polyaeriaatIon worker < L2 yra) 6 I 9501977 foreaai <19 yra> High 6 Years Low 10 Yeara 1964-1970 rent r 1 f uge oper at or 1970-1960 d r I er operar or Hr S J oe 11 it1 h letter ul 20 March 19/H coni Ira* HI. waa a annoner worker wlm was h eav1 Iy emposed, p rubahIy even ore *o than a mirnal reaitor c leaner In f Lrat I 2 yr of cap J uyae ill had been lieav I I y exposed, In tI 974 Liver abnoraaIlly and nee ros I a dIagnoaed. Data nml 1 rned In Or U Hyren 1 et t er Ld.A./ / to CEFir 1 1 e I 1 ' r I 2nd No* I 4M I L run Di David 19 yi * In bib letter nf |*i( Apt I I |9H?, Dr htmtenaim of I ARC aaya In Sweden'a National Board of US Health gives 2D-U2-7D as date ot dlagnoult. for Case 01 and 15-115-72 lor Case 02. CMA 006507 11 i uum i ai ' ii r< 20 up x/ AS i. J ANlHIM ASl S ,25 UK Sheet I LIVER AngLoaarcoM Cauea - (Review Dale: I Ian |98?) i 1 1 1 CtKINTRY AND | REFERENCE | NO 1 ) 1 UK 1 1 2[ 1 1 NAME OR | INITIALS | 1 1 t 1 3 DATE OF BIRTH ! 4 C0HPANY 11 15I 6 1 ai 9 1 10 1 1 1 12 1 1 3 1 14 1 11 11 1 J FIRST VC | FACTORY 1 EXPOSURE 1. L 1 1 DATE OF AGE AT | YEARS OF YEARS OF | DATE OF | HISTOLOGICAL DIAGNOSIS DIAGNOSIS 1 EXPOSURE TO EEPOSURE J DEATH | CONFIRMATION 1 1 ESTIMATED l | EEPOSURE | OCCUPATION | ii i 1 DIAGNOSIS l LEVEL 1 | ii ii i i i li 1\ ti l ii i 1 1 1 15 OTHER CAREER HIGHLIGHTS 1 1 1 1 | | 1 i 1 1 16 OTHER COMMtHIS 01 02 01 04 n 3: > --o o es coa 00 |UJ 1 1 1 1 1 1 1 1 i I 1 1 1 | B.IU 1 1 1 1 | JSR 1 \ 1 i 1 l 1 1 1 1 1 1 i t 1 1 1 1 1 I 1 1 1 ]20.04.01 1 1 J 1 1 1 1 t 1 1 1 1 1 102.06.17 1 t 1 i 121.06.20 1 t 1 i 1 1 1 1 1 1 1 1 1 1 I 1 ICI BP ICI 1 1 1 1 1 1 |HI 1Ihouaef 04.04.44 03.12.72 71 1 20 ii 11 <i ii (Poi 4 i Collier paper eayel I3.II.I2) 1 1 i 1 ii i1 i 1 l 11 ii ii ii 11 1\ 1 1 1 1 1 1 1 Berry 1 i | 00.07.66 00.12.74 1 1 37 | 09 11 1 11 i 11 11 [HI 1Ihoueel 26.04.54 00.06.79 i i 59 | 25 I i 1 1 1 1 \1 11 1 1 11 I1 1I 11 1i 1 1i 1 11 1 i1 11 11 11 J1 11 t 1 1 1 1 11 11 | 77 103.12.72 J I l(fo< t I |Collier J paper 1 3.5 IB 123.12.72) 1 1 1 1 I 1 1 1 124.17.74 1 1 1 [i \ 1 17.10.79 1 1 1 i 1 1 1 i 1 1 1 1 1 1 1 1 1 I I I I 1 J Yea Yea Yea 500 ppa |J944-7 VCK | 194 7-8 Drier| |Lee and Hariy | l.a ncet 1 1946-61 129-06074 |Autoclave |pages 1316-6 loperator 1 1961-66 |Drler 1 1 1 1i 1 1 1 1 1 1 |Dnblone 11abr1 catLuii |r aae High \ 1 |AutorLave |c leaner i 1 1 |Exposure 11lalted tu 1 17.66 - 9.69 J1 Nedliahigh 1 154-5 U.Kglng | Pre-war Hah |pecker 1 1 1 |PIent 155-6 IDrier Plant 156-56 | Autoclave |worker |1939-45 tray Ivehlcle laatntenanre I 1943-54 | flah packer 1 S t 1 1 1 158-61 1 i |Chargehand 1 IDrier JPlant 1 I 161-72 |Eoreaan |C 2/1 Plant 1 1 1 11 11 1 11 11 11 1I 11 1 Page <?1 UK 2 t COUNTRY AND REFERENCE NO UK 05 NAHF. OR INITIALS DATE OF BIRTH 10.01. 14 1931 07 26.04.20 OB.05.24 9 0 0 VW3 UI o *0 Barry Barry Barry &IU CHEMICALS POLYMERS CROUP WPX/ASI ANC I UCASF S,.'h I.IVER Anglosarcoaa Canes - (Review Date: i Jan 1987) 67A 9 10 1 1 ( I? 1 n 1 U 1 ! t Xx X 1i 1 FIRST VC DATE OF ACE AT YEARS OF YEARS OF 1 DATE OF i KI STOLOC1CAI | ESTIMATED 1 | EXPOSURE DIAGNOSIS DIAGNOSIS EXPOSURE TO 1 EXPOSURt ( DEATH CONFIRMATION | EXPOSURE i OCCUPATION t Ii 1 X DIAGNOSIS i 1 | LEVEL * | 1 11 08.01.51 DO.10.79 65 78 71 119.II.79 1 1 1951-52 1 1 1Po1ycLeanet 1 I | 1957-55 1 1 | latex 1 1 11955-60 1 1 | Po I y M on r 1 1 11960-64 1 1 1 Poly 1 1 (Chargehaiul 1 1 1 1964-70 1 1 ICh.rglng 1 1 (operator 1 1 1 1970-77 1 1 |Drier 1 1 (operator 15 OTHER IARFKR H1LHI1GHTS 1 1962 o9.oi.eo *579 X iX 18 12 109.01.80 1 1 Jj J 1 |7 yr 1 |Po1y Floor 1 |0perator T551 1 00.00.to 1 60 1 1 1i iJ 8.2 113.06.80 1 1 1 1 15 yr 1 ICreaaer on j (Poly Floor J 1 | Polycleaner 1 |1963-5 1 1 Recovery 1 11965-197 L ( 11 19.09.50 27.11.01 1 1 <1 l i t \ i i 57 ! iX M 24 125.12.81 1 1 1 1 1 1 1 1 1 1 1 1 J 1 1 1 1 1 1 1 I1 {1 1 11950-1958 |500 ppa |1968-1974 |200 ppa 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 11950-51 i (1918-1948 (Autoclave (Motor Meehan (operator |1948-1950 |1951-1957 |Operator on IChargeaan |Acet y ene (autoclave | Proaluct Ion |bulIdlng (Plant |1957-1974 |Shift laupervlaor lautoclave Ibulldlng - (Never | r1eaned (autoc1avee | but (eupec vInnr1 a t job enta 11 ed| |en( er 1 ng | autor1avea 11 o 1 us pet 1 Ithea 1 (6 {11 III- K l OMMF N < 'i Psge 22 lift Sheet COUNTRY AND REFERENCE NO UK 09 NAME OR INITIALS DATE OF BIRTH OJ.OS.25 04.04.47 00.05*26 o 3 > O o O' U1 o Barry 1C I tllhhlCALS A POLYMERS CROUP LIVER Angl oast runs Cases - (Review Date: J Jan 1907) WLX/ASI - LAND UK ASt- l. tl l FIRST VC EXPOSURE 15.02.50 27*04*66 DATE OF DIACNOSIS 02.01.01 01 05 04 ACE AT DIACNOSIS YEARS OF EXPOSURE TO DIACNOSIS 13 10 TEARS OF EXPOSURE DATE OF DEATH 74.02.01 II HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVE1. OCCU PAT ION OTHFR ( ARI- h K HlCHLICHTS <JTIIL K ( (JHHtN I Medlu X Polyworker ? years on At rylonlt rl le Resin Plant. Also prior to 1950* A years RAF autlnt enanee. 1 years aotor car palntshop. 2 yeara In Craving Dock. High - II Polycleaner aonthe (500 J966-67. ppa). Lon- Spray-drier 18 Months bagger 1967- (50 pp*). 66* Med I'M - Blow-down 21 aontha at ripper (200 ppa) operator 1968-70. Heavy gotxle InforaalInn veil lr I e driver given In untII final Iec t e* 1 IInea. Jft.Dh.H4 t rii Dr D H I Ullllau Barry 19.12.65 02.06.05 I6.09.SJ 03.06.05 19 02.06.05 High Polycleaner Letter ol 1965 -69 I965-6B. 04.06.05 fed 69-79 Low 79-82 Service operator Dr Kfl.il Sal 11. and ] et t er <! 60-69* 04.06.85 Poly Operator Dr 0 H U Uiuim Oesophage.i I 69-79. Leading Hand haeaor r liage d nr i 79-02. oesophagi*J var 1 ret* dm* t n Angl i.Hriii ma.i nl liver Lew I95J-S9 Sp.r. .r Hlpli 59-J4 6agglng Lew J4-H5 f 1 oor 1957-59. Antcx lave Operator I959-B5 Le' ter 2h.Dh.H5 Dr h I 1 e Page 23 UK Shtot4 CHONTRY AND REFERENCE NO NAME OX INITIALS DATE Or BIRTH UK II 02.03.48 (Cl CHEMICALS A POLYMERS CRODP LIVER AngloaarcoM Caeca - (Review Date : I lauuary J987) PLASTICS DIVISION WHK/ASl 2 - l.ANl, 1IK ASe :s, } Barry 12 FIRST VC EXPOSURE YEARS OF DATE OF AGE AT EXPOSURE YEARS OF DIAGNOSIS DIAGNOSIS TO EXPOSURE DIAGNOSIS DATE OF DEATH HISTO LOGICAL ESTIMATED CONFIRM EXPOSURE OCCUPATION ATION LEVEL _L OTHER CAREER HIGHLIGHTS OTHER COMMENTS 02.06.B6 High Low High 1 Polyc leaner| Moved to |Regained 11948-69 (Acrylonl- |Jan 1966 | Central \trl le |Depot |Plant |1969-70 |untII left |Polyfloor IBP 1981. 11970-71 |Manager ot 1 |1C 4 SS 1 |Ltd at 1 ICardllf 1 |A1rport 1 11963-86 1 working actively, uni 11 O I* I 3. i i * >ii ill Oil i O| i i O'- i i i IIII ili li l iii)i i ill*iii i l l 1 l lii' i i i i i ii ill l i i l Page 21* USA Sheet I U CHIMIGALS 4 POLYMERS i.HUUP LIVER Anglosarcotaa Cane a - (Review Dale: I Jan 1987) UK syst en of dalea DAY - MONTH - YEAR WrX/ASI - UNCiUl AStS.'H \ 12 13 A 15 COUNTBY AND REFERENCE 1 1 | | 1 _L 1 NAME OR | DATE OF INITIALS | RIRTH J 1 1 COMPANY | FACTORY NO USA 01 1 J 1 1 1 (Earl l J _L 1 1 1 117.10.23 RFC 1 _! 1 1 1 | Louie- 1 Parka 1 1 vltle 11 \ 1 1 1 J 1 02 1 1 1 1 J 1 1 19.08.31 1 PC 1 \ i j 1 |Louie| villa 11 11 1 1 J 11 0) | Edva rd I2S.05.IS PC |Dinwiddle 1 1 1 |Louie- 1 vlllc 11 1 j j j 11 1 04 1 MS, 01.24 BfC | Louie- \1 | villa J 1 0} 1 J 1 I2S.01.12 PC 1 1 | Louie- 11 | vllle 1 i 06 |Ray J 1 123.11.28 PC 1 1 | Louie- \ Auat In 1 | vllle J Jonee? 1 1 11 1 11 1 11 1 11 1 11 07 J Chari ea (03.05.22 ucc 1 |S Charle- | T Snarl 1 | eton JJ 11 1 1 0B 1 IO6.0S.20 Goodyear (Niagara 6 -L 7 _L a FIRST VC UPOSURE DATE OP DIAGNOSIS ACE AT DIAGNOSES 9 YEARS OF EXPOSURE TO DIAGNOSIS i i 09.12.48 03.03.73 49 24 i i i J. IS.M.55 00.05.70 i _L 17 14 i 28* J1.45 19.12.73 58 _L I 06*07.52 I 19,08.67 _L I 1 19.06.44 09.04.64 43 52 1 l 28 IS 20 i 17.01.62 00.02.74 45 12 I i \ 27.OB.44 00.00.68 J I 45 i 24 I X1 \i 07.10.46 00.08.61 * 41 i 15 i 1 1 1 ! \ I in 1? JL 11 YEARS OF | DATEOF | HISTOLOGICAL EXPOSURE | DEATH | CONFIRMATION 11 L________ ____ 1 11 11 11 21 103.03.73 | Yea ii ii 11 t1 11 11 11 LI J27.09.71 1 | ( NJOSti | laaye | I28.09.7IH Yea 1J 11 28 119.12.73 | Yea ii ii ii 11 IS 107.01.68 | Yea i ii ii 11 20 (09.04.64 | Yea ii ii 11 12 124.07.75 I Yea 11 11 f1 ii ii 1 ii i1 1 7 123.03.68 | 11 if 1l 15 129.08.6J | Yea Yea 1 1 1 1 t 1 >4 t 15 | K. 1 1 EST1HATED 1 i EXPOSURE 1 OCCUPATION | OTHER CAREER 1 imitx | COHMlNlh LEVEL 1 | HIGHLIGHTS 1 1 1 1 |Pol Cleaner |(Block Jana | 1974) p S3 1 1 1 1 |H)story given |Rolling Siune |in Anna!a NY | Art 1 ACAD SCIENCES |Ref 1 NY Arad |Vol 329 (1979)|of Sc Synp Ipage 190 in 11974 |Paper by (Also Blurk ! R Cottlne of|Jana 1.7.74 IOSHA IP 51 1 1 |Pot |(Cf Cleaner Block) 1 1 IRef 1 | A ] so Bio. k 1 1 t y |Pot |<Cf 1 i 1 |Pot |(CI Cleaner Block) Cleaner Block) 1 |Louiavl1le (Courier |Journal (02-09-80 |JAMA 1.7.74 ip ii IRef 1 (Also Block 1 1 Ref 1 (Also Block 1 1 (Pot t(Cf Cleaner Block) i IRef 1 JAEso Block 1i 11 JUS Air Force) i |Pot Cleaner |(Cf Block) IRef 1 t |Loulsv1 lie | Tines 2 1.7.75 |Ret 1 red Ap r11 1 1 1974 1 (Also 6l.uk 1 1 1 (Ref 1 1 1 1 1 (Kef | T S 9 0 0 VWD Page 25 JCI CHEMICALS A POLYMERS GROUP LIVER Angluaarcoaa (.ayes - {Review Date: I Jan 1967) UK ayaten ot dates DAY - MONTH - YEAR UVA/ASL 2 - LANGlOCASKS.i COUNTRY AND REFERENCE NO NAME OR INITIALS DATE OP RIRTH FACTORY FIRST VC UFQSUIE DATE OF DIAGNOSIS ACE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS OP EXPOSURE DATE OF DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS I ] on ok COMMKNfS Raymond GetlleF1 nger? Louis ville 26.OS.45 01.03.74 43 24 2000 ppai \ fRef I han {wrong f f gu n*h |re flrat tevpoeuie, I Lon lav 111e (Tinea 129.10.74. I I?.3-75, I 10.3.ft Goodyear Niagara ]2*06.51 00.OS.66 SS Goodyear Niagara 14.10.46 00.03.70 1t 11 l i 12 |Franc la A |I7 1I.IR \ FI reatone 1 *ot tatounl 13.07.49 | 02.0S.69 i 50 i 20 |Sac Naan 1 Pa | 1 i 11 11 t 1 \1 11 i 11 11 i 1 1i * 11 11 i 11 11 i 1 ________ L L! .1 J3 Richard 01.12.21 Edwa rd Clendenln _L S Charle ston 11.12.42 00.OS.74 S2 n 3: > o o to ut w 17 t 11 1 19 t02.0S.69 1 J 1i i i\ i 11 1 \1 1 \1 1 11 i 11 i _J 07.04.74 I Ref I I | Ret Yea 1\ IHigh 10 yra|10 yra aa i | tit 111 c y 6 IRef 1 + letter 1 Ireactor op. |Service op. |of 2b Aprl1 1 |(not cleanerlSagger 11976 f roai 1 \- aeparate fDryer op. IRusael ( A Pari* 1 |crew cleaned! Strlpplng up. Ito J T Seawe1J 1 |autoclavea) |3 yra prior Io f MCA 1| {service In | 11 |tyre plant i -i )! 1 2000 ppm t | Char I eat on tDally Mat! 121.7.7S l I Never d lag|nosed as angII osar< ou nl 11 tver. | nt mo te t I on f,lvni In tletIer II May 11904 tinn | J A Salg. I At * OllJlt Hilt , I ASI - N. i w I | J ciir i 4 j I Vl M | e m|hjmj r . Pane 2f> USA Sheet 1 I Cl CHEMICALS 6 POL I'M Kits GROUP LIVER Angloasrcoaa Cases - (Review Date: J Jan 496 7) UK. Syetea of dates DAY - MONTH - YEAR WPX/ASl_l - I.ANt.loCAse s . i COUNTRY AND NAME OR REFERENCE INITIALS NO _L 1 DATE OF 1 IRTH 1 COMPANY 1 _L II i I FIRST VC | FACTORY | EXPOSURE DATE OF DIAGNOSIS 11 L L J- AGE AT YEARS OF 0IACN0S1S EXPOSURE TO DIAGNOSIS _L YEARS OF EXPOSURE DATE OF DEATH H t STOI.UC] CA] CONFlRHATION ESTIMATED EXPOSURE 1 1 OCCUPATION | XX LEVEL XX 1 l OTHER CAREER HIGHLIGHTS 1 | j * niHt R < onm NTs 16 J Janes 104.11.27 RFC |Howard 1 1 1 J 1 1i 1 1 7 |peerenbooa |0b.D5.11 AFG 1 1 1 1 t *i i 1 16 |Char11e 122.04.26 RFC |Arthur l 1 1 1 1 VUgt l Christian |Loula | 00.05.50 00.00.69 1 4J 19 (villa 1 1 11 1 11 1 11 1 11 1 11 1 * |Louis (villa 1 1i | 23.06.55 11.10.74 | 1 1 41 i 19 11 1 J1 1 11 1 11 i 1 ii i i 11 (Avon Lake| 15.09.54 1 00.00.75 1 46 21 11 1 11 i 1 11 1 (1 ( 11 1 11 1 S Char le st on 19.06.75 11.00.17 Goodyear Niagara 00.00.55 Cheater Hinkle 02.09.09 S Charie st on Early 77 21 1 04 (27.03.69 Yea 1 |195l-4 VCM IFron 1954 |Tabfe 4 In 11 11 1 Ipolyner- (onwards In |Wagoner 1 llsatlon |Amy and other | TesManny to 11 11 laervlce. (US Senate 11 11 (46-50 Amy |Cont 1 meil 1 n 11 11 1 |H N Johnson 11 11 1 (It r 07.HR.76 11 I ii Yes 1 1 19 |16.10.00 on 11.10.74 i 11 but no 1 1( poet-norten 1 11 16.10.60 1 1 1 i 1 1 1 1 1 ( 1 1 1 1 | Dr M N Jotmaon (letter of 124.2.61 run| f 1 raed deal h 11 11 1 |6 years altet t ii !1 i |d1 agnosia 11 1 1) |02.11.75 (1 11 11 11 11 1l Yea 1 113 yrs J (Navy (autoeleaner) 10 yrs on | |Eatol (Tyre Store IplastJclser| |1 Carboset | (operation | 1 1 1 1 1 ( 1 1 (Coni 1 nsetl 1 n (H N Johnaoi; (11 r 0 7.UR. 7 6 |Alan Roll 1n |St one nag. 1 15.111.76 1 06.04.76 I (WillIdsspoi i | Su n Caret t * |JI luoe I 9 J S |Char I eat on |Da 1ly Half 121.7. 75 1 | NltlStl inter |oi 25.NS.79 02.ni.77 I (26 y c r. wl i I. | ires at '>* | Re l i r il | News r I e * | 2 1.2.77 t frTSVOO VW3 Pan*. 37 USA SItee* 4 ll I CHKHIIAIS A |'<ILYHI-KS {.KOIIP LIVER Angloaarrona Canes - (Review Date: | Jan 148/) DK ayalen of date* Ik A V - MONTH - YEAR UPX/AM _2 - LANl. IO< ASi 5, \ COUNTRY AND REFERENCE NO NAH OR INITIALS DATE OF birth FIRST VC EXPOSURE DATE OF OIACNGSIS ACE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS OF EXPOSURE DATE OF DEATH HISTOLOGICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS OTHER COHHENIS USA 02.10.2) Lou lavilla 11.07.47 29 Great FI tchburg OB.09.5R 06.04.73 American Maaa. Chenlcal Conpany ll ctrarle* I7.05.IT ucc S Charle- I *19 iJ.os.Jf Edward aton Moore 60 1* TTsT Renutva l I Ton i eg a t er ronf med in R KanlnaRI let er of 5 Novenber I9BO 28 14 06.04.73 lx>u Isvlltr Tines 26,I./6 aalil he was Che |Ot h AS vIt cla at Bella l me ill whim b hail died by 26.I.76 I ii h l a letter of 16.<19.Hi Dl M N lnlmuim c on f 1 ran I h J a la the cane detirrl bed by Uannalier Taahurm A Yaa In Feb I4KO An J Med I I Vo I JO p?HO --------- iIT" <HIOSH .ay. It) 27.05.77 Cholanglo- (R Rant nakl 26/2/79) _L Hedlun to high for 24 yra _L 1941-65 non- 1937-39 vat aolvent off and on vinyl realn Iabourer unit and 1939-41 nay dlaperalon have been vinyl realna eapoaed aa unit flrat r eact or aa fitter c leaner helper* then I 94 3 bet ane ehl f t ahlft fitter utility nan 1946 herane ahift utility a u 26.04.65 enploynent was t enal oat ed N M Wheeler letter of IR.B./7 to i Stal f otd g l vee deuNi Rose KatilnaRI letter of 26/2/79 R Kan I risk I { 5 Nov |9hi atfgge a t a t toil NI OSH wi Ik letalu on r eg I *it e r s t m c this neop I .ink nay he <iwoi I at eil wl i Ii AM . R N Wheel* I el let id 2tl/ 2/ 79 o Rose Kami i jflli-i . .ll tunn'i ..-i 5/11/Ho CMA 0 0 6 5 1 5 pm** 26 USA Sheet 5 1(1 OiJ MI C'AI '! A POLYMERS <Jt1IUP l.iVEH Anglosarroafl Cases - (Review Date: Jan 1987) UK ayatea ol da tea DAT - MONTH - YEAR UPX/ASI. I - I.ANI. liMIASk- S f 10 11 IS lli COUNTRY AND REFERENCE NO USA 1 NAME OR INITIALS i DATE Of BIRTH 1 FIRST VC DATE OF ACE AT _YEARS oY | ttARS OF DATE OF | HISTOLOGICAL ESTIMATED OTHER | OTIOK EXPOSURE DIAGNOSIS OIACNOSIS EXPOSURE TO | EXPOSURE DEATH | CONFIRMATION EXPOSURE OCCURATION IAKKKH | LOHNINIS DIAGNOSIS X. LEVEL HIGHLIGHTS I 11 1 1 l1 11 1 1 26 | John Berry(07.07.21 | RFC 1 11 1 11 1 11 t 11 1 11 I 1I 1 11 1 J1 1 11 1 11 1 1( 1 11 1 i1 1 27 |J L 1t |11.03.16 1 ucc 11.04.17 29 12.10.07 I Lou la- ( 03.10.47 DO.00.77 52 1 Ivin* 1 1 1 1 1 (up to 2 year# after (death) 1 1 1 11 1 death) 1 11 1 1 1l 1 1 11 1 1 11 1 11 1 1 11 1 11 11 11 11 11 11 |S Charle -1 0l.07.tl Jo.11.>8 1 1 62 1 1 1 .44S Charle DO.OR ston 03.11.70 S Oiarle- 00.03.42 aton O0.03.R0 61 72 78 (death) 37 34 30 1 ta 111.02.75 1 | (1 1 11 1 11 1 11 1 11 ( 11 1 11 I i1 1 1 | | | | 1 20 lOtiosH l l l l 1 1 (23.11.7R 1 1 | | 1 I 1 llifl 27 (and C |Dally Mall |25> I 33 01.11.78 j xi 16 01.03.00 | Yea Yea x 30 22.07.22 Tenneco Meal ngt on 11.06.64 30.12.00 Cheatcals 17 30.12.00 31 o 3: > o o 0cn 00.11.23 S Oierleat on 12.03.46 01.OR.01 33 13 |Exposed In | Va r f oua | nbt | leone degree |In PVC | | R lul iihk 1 11 eM ei nl Ito 22 |planta f roa | 126/2/79 an.l Irhealcala (cold rooa to| |Prof. Ta*hn r1n (but Main Ipaate 1 leapoaure Irecovery to J (was to YCH, |PVC charging) (letter nl 19/1/79 | 1 probably Ihigh 1 1 1 1 1 | 1 High loperator to | Ipaate 1 (charging. | (111 August | 11965. | |Terminated | lea^tl oyaent | (Jan 1966 I (Operator to (Exposure In t l 1 l 1 1 | 1 (R N Wheeler bulk and 111 r of 4 Ian dispersion PVCIJ979 and Manufacture (Char I eat on |Dally Mai I llO.IUH and |R Kantnek1 (26/2/79 |R KaalnakI (letter nt 16/4/79 |R KanlnakI (Letter* ul |t9th Imie I9HII |t 3t li Nnv I VHP 6 - Unknown Halntenance 9 - Hlnlnal Mechanic 6 yra Elsewhere n ii* Roller house Operator High {Rut Cheailral not aa high Operator In aa 1eactor c harge c leane r rear!or von 1 d experience) Worked aa Iahouret t rot In 11c I 94 I In Hay 1946 h 1 ill may li av e < I t'riiieil 1 e.11 iniii 11 | I IlHl t IfflC Fro* 1939 to IDr f)a-ey 19 76 AM phat lr| I e( t e r ClicalrtU Jlh.IO.HI operator anti JR H Ulni l Iron Inly 19 7b | I ei t * r .<1 1 o dttt e forenan All plint I r |9.it.HI. | Al t... Or It t J I *1 I 1 ill Clien) cal 0|>4* rat I nit I (I l .11 \. M I 1 j il al i>l .l> I Page 29 USA Sheet 6 H I CHFMICAI.S ft POLYMERS GROUP 0 LIVER Angloaarcona Cases - (Review Date: L Jan 1967) UK systea of dales DAY - MONTH - YEAR UVX/ASl 2 - LANGlOt ftSk s ,, 11 1 11 1 1 2 (1 4 f11 6 7 6 1 9 1 io 11 17 |n | J4 | 11 1 16 COUNTRY AN0 REFERENCE 1 NAME OR | DATE OF INITIALS I iIRTH COMPANY 41 11 1 1 FIRST VC I FACTORY 1 UPOSORE DATE OF DIAGNOSIS i i ACE AT | DIAGNOSIS | YEARS OF | EXPOSURE TO | YEANS OF EXPOSURE DATE OF DEATH 11 1 11 H ISTOLOCICAl, t ESTIMATED | 1 f CONFIRMATION | EXPOSURE | OCCUPATION | OTHER CAREER 1 1 | ortOK | CIJMHMHS NO 11 1 DIAGNOSIS J LEVEL | | HIGHLIGHTS 1 US 12 US 11 i C U ClrouK |22-02-06 i S Ferguson 108-10-27 Monsanto RFC 1f 4* Sprlngf laid I5-I0-M 1 Naaa J 11 ii 1J 11 11 ii ii 14 11 11 11 11 11 11 11 11 ii 11 |Louisville 09-09-14 00-07-79 11-01-82 1 1 71 1 26 1 1 1 1 1 1 1 1 1 1 1 4 1 l 1 1 1 i 1 14 1 28 1 14 |(1n PVC (autoclave (area) i 4 26 17-05-00 Alive An autopay was done and (Mediate cause of 41 1 11 |The death |1940-1911 1 | (certificate!Various Jobi| (gave 11n potyner | (Hr Giroux* laisnutsrture | death given (usual (RUTVAR aa loccupstlon | LUSTItEX "AngloearcoM '| aa "RettLe|1911-1964 | J ( loperator** IVarioua |obs| 11 n 11 n and | ("chenlcals (around PVC J (Industry**, (autoclaves J | | 1964-1971 | | IVarioua | | (clerical | | dobs In PVC | | |polywerlsat Ion | lllcllit)/ 1 | (Retired | | (01-01-71. | 11 1 Yea | (Multiple | Jobs 1 1 | ] nl iimaf 1 in Iglven In (letter of | Februar y |fu* Ur 24 9H2 |Walter < | Ear uei of IMunaant u (Spr Lngt11 d ( | Or A Mi*mi ol | Honoanl o |Eurupe. 1 ( 1 1 1 1 i 1 |Prof Tanb *r letter of > Includ log 12 Auk 1962 Poly Dr H N JoIiiih.i Operator + I el Ier of eaner. 26 Feb I SKI. US 14 1 |Nr Byrial 1 1 1 1 1 --J 11 (29-01-34 | RFG 14 14 14 14 44 44 4 Louisville 1 1 4 1 ___ L 1 ! 1951 14 4 03-11-82 4 48 44 11 11 11 11 1 J__ ____ 27 1 I1 1 10 404.06 61 |Yea 1 41 41 1 11 1 14 1 11 Jl _J________ l.... . J1 1 Poly |1965 left (Operator + | to becoaie (Autoclave IClerftjm.n (Cleaner 4 11915-65. J 11 IJ 6FC a 1 JDr H N lolman 11 et t er of |1 Nov 1967, 128 Feb J9HI land 9 Aug |I9N4. 1 09-01-12 S Charleton 21-07-44 10-07-63 19 16-07-01 High fro* 1944 to 1951. Nedlua froi 1915-1918 Ur |)a**-y letlei of 1 Sept *96 1 CMA 0 0 6 5 1 7 US 16 The Central Aahts Tire and Ula Rubber Co 21-09-61 Moderate 1916-56 Labourer 1916-17 prod helper 1917-70 operator 1970-71 e Ler t r 1* Ian 19 71-preaeni ope rat or ft V I riomli I. 1 *l l ei of I? Si-pi I SHI. spot led HI Mf-d Hal Hay M* I. Tr * 1 l i IK Hay ISMt Page yO USA Sheet J IU CHEMICALS 6 POLYMERS GROUP LIVER Angiosarcoma Case* - (Review Date: I January UPX/ASJ .1 l.ANCItM AM s ,u UK aysten of dnlvy DAY - MON1H - YEAR 11 12 11 * 1 l COUNTRY AND |NAME OR ( l OATE Of | REFERENCE |INITIALS BIRTH | COMPANY NO ] 1 USA 17 11 1 1( (Hr J 29.06.291 RFC |Payton 1 It I1 11 11 11 11 1 1 ____ 1 1 i1 10 |JU0 20.06.271 Air 1 (Producta l1 11 11 11 1\ l\ 1\ 11 1 11 11 11 !1 l1 19 |J Hem Ice 27.06.101 Pantaaota i \1 11 11 1i 1\ )l 11 i1 1I o1 3: 1 >1 1 1 l 1 o1 o1 O' 1 Ul J-t 1 00 1 1 1 1 1 1 * 1 1 ( 1 i1 1 5 16 J 1 |FIRST VC FACTORY | EXPOSURE 1 ______ J i Louin- I villa 1953 i 1 i 1 1 1 i ______ j i Calvert 100.02.63 City 1 1 i 1 1 i 1 1 1 \ i 1 ______ J i Faaeatc 1 1 1 1 i 1 i 1 ( 1 I960 1 1 I i 1 1 1 \ 1 1 1 1 1 1 7 | 6 19 11 I ID I 11 OATE OF j ACE AT _JL 1 |YEARS OP 1 (EXPOSURE I YEARS 0F| DIAGNOSIS! DIAGNOSIS)TO | EXPOSURE) (DIAGNOSIS) 1 DATE OF DEATH 1 1 1\ 06.00.84 | 34 1 11 1 27 106.00.04 1 1J 1 11 1 11 1 1i 1 1) i i1 1 l1 11 ) L tJ 1 i i) 19.01.04 | 61 1 20 I 70 )26.10.01 i ii 1 Ji 1 11 \ 1 1 1f i ii 1 )1 1 1) 1 11 1 11 1 11 1 11 1 11 March 1964 | 63 i 1 24 |1 1 1 i 1 1 1 i i i i I i i i i i i i i i i JL J ii | 21 129.06.04 11 11 11 i1 11 11 t1 r) i1 i) i1 i1 i1 i1 i1 i i i1 i1 t1 i1 i1 i ____ HJSTO- 1 13 1 1 \ 1 __ || 14 |1 1 13 1 )i || lb LOGICAL |ESTIMATED) |OTHER | CONFIRM-IEXPOSURE (OCCUPATION ICARERR 1 ATION [LEVEL | JNICHLlCHTSl OTHER COWtENTS ____ Yea taa Yaa 11 | 1 | t High |Worked | (regularly | 1 In PVC .real 1 In the | (early daya | |wan a | Ireactor | (cleaner | 1 11933-75. | 11 11 1 High I Normal | |I961-I962|progra*lon| |f roa helper| |to aenlor | (operator* | (cleaned f Jreactor*, | let ripping | l.nd 1 (recovery | (arena aa ( (well aa 1 (charging ) | (operator. | ii 11 | Low 129.09.60 - (Worked (May 66 (before (Vinyl 11960 )Fabrication!with US (Plant (Alt | High (May 66 - (Force, (Aug 70 |United lUtlllry J Wool JRealn (Dyer* (Operator (and |(lnc Jul bbfOkanlte Sep 67 J (Reactor | (Operator) | | Low |Sep 70-02 | |Hononer | |Opera tor | j Low |I9H7-81 1 Mi 1 t | | | Operator. f (Calendar | |Shop, nutl1| | ret trement | 11 1 | (Information given In letter 09.08.H4 (fro* Dr M H Johnaon ) 1 1 1 1 1 ( l (Throabo cytopenia and Leukopenia since (alnca 1970. Cold treatment (or arthritis (1976. Under Dr*a care about 6 months (before death, had panned standard phyali al examination 1 monthe earlier. J Barr ll.ttet. at 22.10.84 nd 21.01.85. 1 1 ( 1 \ 1 1 1 1 1 (Never In hoepltal for any chronic or lacuta medical problems. Death certificate latatea cauae of death cardlo-pulmnnary larreat aecondary to angloaarcoma of (liver. (Letter of 15.07.86 from John E Ertel (of Pantaaota with letter of 24.02.Hb (from Dt Auerbach, Pathologist. 1 1 1 1 1 1 1 ( 1 1 1 1 ( l 1 1 l pm* 31 YUGOSLAV I A Cl CHEMICALS fc POLYMERS CROUP LIVER Angloaarcoma Caeca - (Review Date: I Jan |9B?) WX/ASL - I ANUOt AShs, 1/ COUNTRY AND REFERENCE NO NAME OR INITIALS DATE OE 81RIW YUGOSLAVIA OL JllftO Vlnll Jugo Vlnll Jugo Vlnll YEARS OF FIRST VC MTS or ACE AT EXPOSURE YEARS Or FACTORT urosvtB DIAGNOSIS DIAGNOSIS TO EXPOSURE DIAGNOSIS DATE OF DEATH 12 HISTO LOGICAL CONFIRM ATION X ESTIMATED EXPOSURE OCCUPATION LEVEL OTHER CAREER HIGHLIGHTS X OTHER COMMENTS Split 00.00.53 ot.04.n Split 00.00.50 12.07.7) Split 15.12.56 03.09.76 20 08.04.73 12.07.7) 18 03.09.76 VCN Production SAJIIC t al paper Env Health Perspective Vo I pp 169-192 197b 17. Mn hla letter of 1 Oct 1978. Dr Splrtau nt NIOSH changed the etafua of Caae 02 to VIM production employee. Dr Splrtae also notified a new Caae 03 alao a VCM pToduitlun worker. Roae KamlnaM letter of 19 June 19811 and I ARC letter of 1 April 1982 o 3 > O S> tn Page 32 Incidence of ASL Cases Per Annum TABLE By date of death 1 (Review Date - 1 Jan 1987) 1955 .............................................................................................. 1 60 7 8 9 1960 1 .............................................................................................. ........................................................................... .............................................................................................. ............................................................................................. 1 0 0 0 1 21 3 .............................................................................................. 0 4 ......................................................................................................................................................... 2 5 6 7 8 9 1970 1 2 ............................................................................................. ........................................................................... .............................................................................................. .............................................................................................. ..................................................................................... .............................................................................................. ............................................................................................. ......................................................................................................................................................... 0 0 1 5 3 2 3 5 3 .............................................................................................. 8 4 .............................................................................................. 5 5 ...............................................................................................11 6 .........................................................................................11 7 ............................................................................................. 9 8 .........................................................................................10 95 1980 ............................................................................................... 10 1 ............................................................................................. 5 2 ........................................................................... 2 3 10 4 ............................................................................................. 7 5 ............................................................................................. 5 ........ .............. .............. ...6 2 Total 125 N.B. 1 Does not Include Italian 01 but does include German 03., 2 The 1977 total includes US case 24 which is a Cholangiosarcoma. 3 The total does not Include US 33 and 36, F 15 and G31 and 32 who are alive CMA 0 0 6 5 2 0 Page 33 Distribution of ASL Cases by Country TABLE 2 (Review Date - 1 Jan 1987) USA W Germany France UK Canada Sweden Yugoslavia Italy Czechoslovakia Japan Belgium Norway 36 *** 31 ** *** 2 i *** 12 10 5 **** 4 ***** A* 2 2 2 1 Total 130 CMA 0 0 6 5 2 1 * Omit ItOl - atypical case of PVC bag extruder. ** Includes G03 aerosol can filler. *** Includes case US 24 which was diagnosed as Cholangiosarcoma; & US 33 and 36, F 15 and G 31 and 32, who are alive **** Includes one monomer worker. ***** includes two monomer workers. i.e Western Europe North America Rest of World 76 46 8 Total 130 Page 34 Pattern of ASL Cases by Factory TABLE 3 (Review Date - 1 Jan 1987) (a) W Europe Of the 76 cases in W Europe, 65 have occurred in clusters at 11 factories. Of the 31 German cases, 28 have occurred in clusters at 4 factories, ASL Cases Dynamit, Troisdorf, Germany BP, Barry, UK Wacker, Burghausen, Germany Chloe Chimie (Formerly RP), St PCUK, Brignoud, France Kemanord, Sundsvall, Sweden CWH, Marl, Germany ICI, Hlllhouse, UK Solvay, Tavaux, France Lonza, Waldshut, Germany Solvay, Jemeppe, Belgium Fons, France 12 9 9 8 7 5 4 3 3 3 _2 65 NB: There are 32 pre 1962 PVC plants in W Europe; 18 of these have had ASL cases (Ref Table 8) (b) N America Of the 46 cases in N America, 38 have occurred at four factories out of a total of 54 factories:- In N America 42 plants have not had ASL cases. ASL Cases BFG, Louisville, US BFG, Shawinigan, Canada UCC, S Charleston Goodyear, Niagara 14 10 10 4 38 NB: There are 28 pre 1962 PVC plants in N America; 12 of these have had ASL cases (Ref Tables 94 10) (c) Rest of World The 8 ASL cases are believed to be in 1 cluster of 4 and 2 clusters of 2 cases. WPX/ASL2 - LANG10CASES,10 C C S 9 0 0 VW3 Page 35 TABLE 4A (Review Date - 1 Jan 1987) Latency Periods (Years from first Exposure to Diagnosis) W Europe Count ry Belgium No of Cases 2 Total Years 35 Average 17.5 France Germany Italy Norway Sweden 21 545 25.95 * 31 632 20.38 * 4 74 18.5 1 22 22 5 122 24.5 N America UK 12 272 22.66 * 76 1702 22.39 W Europe Average US 36 910 25.27 * Rest of World Canada 10 204 20.4 * 46 1114 24.21 N America Average Czechoslovakia 2 30 15.0 Summary Japan Yugoslavia 2 4 8 39 19.5 85 21.2 154 19.2 Rest of World Average CMA 0 0 6 5 2 3 W Europe 76 1702 22.39 N America 46 1114 24.2 1 Rest of World 8 130 154 2970 19.2 22.84 World Average * Of the countries with > to cases, France, and USA have an average latency period above world average, Germany, UK and Can.id,i below world average, ' Page 37 (Review date l January 1987) TABLE 4C LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE MAX POSSIBLE | YEAR OF 1 LATENCY PERIOD I FIRST EXPOSURE 1 LATENCY PERIOD (NO OF YEARS) | ARITHMETIC MEAN 1 | OF LATENCY PERIODS 1 11 11 47 | 1939 1 38* | 1 46 | 1940 ] 1 244 = 34.86 1 45 | 1 1 37.21,37,41 |7 1 44 1 2 1 32,38 | 1 43 1 3 1 38,14,32 | 1 1 4 1 28,11,24,20,24,34,39 | 718 = 26.59 1 | 5 1 27,22,28,29 | 27 1 1 6 1 21,29,31,26,28,15,23,1 1 1 1 30,35 | 1 39 | 7 1 29,24,29,28 | 1 38 1 8 ! 28,24,34 | 1 1 9 1 30,26,20 | 521 = 24.80 1 | 1950 1 26,22,31,19,23,14,33 | 21 1 | 1 1 19,28,17,28,34,29 | 34 | 2 1 21**,15 | 1 1 33 1 3 1 25,22,23,22,20,31,22,1 1 1 1 32*** | 1 1 4 1 21,21,25,25 ,21,28***J 1 I I 22 | 787 = 22.48 1 | 5 1 22,23,24,14,19,21,27 | 35 ! 1 1 27*** 24,28,30*** | 1 6 1 21,12,27*** | 1 29 | 7 1 19,17,15,13,16,28 I I 28 1 8 1 18,18,15,17,20 | 1 1 9 1 16,21,25,27 | 490 = 18.14 1 1 1960 1 13,18,21,25,24 | 27 1 | 1 1 15,16,16,16,19,19,12 | 1 24 1 2 1 13.18.17,12,18,21 I 1 23 I 3 l 16,17,20,21 1 4 1 16,17 |1 I 180 . 16.36 1 | 5 1 11,19 I 11 1 1 6 1 9,18 19 | 7 1 16 I I 1 I 18 | 8 1 18 1 9 1 13 I 1970 1 I1 1 31 a 15.5 1 12 1 VIOLA |1 1 14 1 2 13 1 3 1 I4 | TOTAL I 1 130 CASES 11 1 1 MALTONI 1 1 GOODRIC1 | 2971 22.85 1 11 1 130 1 * Cholangiosarcoma ** Aerosol can filler *** US33 and 36; F15 and G31 and G32 still alive. WPX/ASL2 - LANGIOCASES,13 CHA 006525 TABLE 4D Page 38 (Review dace 1 January 1987) LATENCY PERIODS OF A5L CASES TABULATED BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION ` " MAX POSSIBLE 1 LATENCY PERIOD 1 1 47 1 46 1 45 1 44 1 43 1 1 1 1 39 1 38 1 1 1 1 34 1 33 1 1 1 1 1 29 1 28 1 1 I 1 24 1 23 1 1 1 1 19 1 18 1 1 1 1 1 YEAR OF 1 FIRST EXPOSURE I 1939 1940 1 1 ! 1 1 2 3 4 5 6 7 8 9 1950 1 2 3 4 1 1 1 1 1 1 1 1 1 I I I 1 51 I 61 71 8 9 1960 1 2 3 4 5 6 7 1 I I 1 1 1 1 1 1 1 VIOLA 8 9 1970 1 1 ! 1 2 MALTONI 3 TOTAL CASES 1 I 1 LATENCY PERIODS IN WESTERN EUROPE | NORTH AMERICA | I 38* 37,41 I | 21,37 1 32,38 38 | 14,32 28 | 11,24,20,24,34,39 27 | 22,28,29 21,29,31,33 29 28,34 | 26,28,15,23,30,35 | 24,29,28 | 24 30,26 26,22,31 1 20 | 19 19,28,34,29, 21** 25,22,22,32*** 21,21,25,25 | 17,28 | 15 1 23,31 | 21,28*** 22,23,24,27***24,281 14,19,21,27 30*** | 21,12 | 27*** 19,17,15,13,28 18,18 16,21,25,27, 1 | 15 | 13,18,21,25 | 24 15,16,16,16,19,19 | 12 13,18,17,18,21 I 12 16,17,21 16 I 20 I 17 11,19 9,18 16 1 I | 18 | 13 I 1 ) 1 1 76 I 46 * Giolangiosarcoma ** Aerosol can filler *** US33 and 36; F15 and G31 and 32 still alive 1 ROW 1 1 1 1 i i 1 1 1 1 1 ! 1 23,14 1 I 1 22,20 1 22 1 1 1 16 " | 17,20 1 1 1 1 1 1 1 1 1 1 1 1 ! 1 1 18 WPX/ASL2 - LANGIOCASES,14 CMA 006526 TABLE 4E Page 39 (Review date 1 January 1987) PLANT 11 I START 1 I UP 1 ! DATE | LATENCY PERIODS OF ASL CASES IN SPECIFIC PLANTS (10 OR MORE CASES) I1 | NO OF | AVERAGE | CASES | LATENCY PERIOi 11 LOUISVILLE 11 1 11 I | 1940? | 12,14,15,19,19,20,24,27,28,28,28,29,29 1 1 1 14 | 23.07 USA TROISDORF 1 1 31 11 | 1954 j 12,13,16,16,18,19,19,21,23,25,28,29 11 1! 1 12 | 19.91 W GERMANY SHAWINIGAN 1l ii I 1943 1 11,12,14,21,22,23,24,24,26,28 1t 11 ! 1 1 10 1 20.5 CANADA I(1941?) | ii 11 S CHARLESTON I 1939? | 24,30,32,32,34,35,37,38,38,39, 11 1 10 | 33.99 USA 11 11 11 11 WPX/ASL2 - LANGI0CASES.15 CMA 006527 Page 40 (Review dace 1 January 1987) TABLE 4F LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT (10 OR MORE CASES) YEAR OF FIRST | LOUISVILLE | TROISDORF | SHAWINIGAN | S CHARLESTON EXPOSURE I USA | W GERMANY | CANADA I USA 1939 1940 1 ! I I 38 1! 11 1 21 1 37 21 31 4 1 20 1 1 14 1 11,24 I 32,38 I 32 ! 24,34,39 5 1 28,29,27 61 7 1 29,28 I 22 I 26,28 1 24 1 I 30,35 1 8 9 1950 1 24 1 1 19 11 11 1! 11 I 29 I 1 2 1 15 3 1 31 4 1 28 1 21,25 5 1 14,19 I 23,28 I 23 1 1 1 1 1 1 61 71 1 12 1 13 1 1 1 1 81 91 11 11 1960 1 11 11 2 1 12 I 16,16,19,19, 1 12 I 18 1 1 1 WPX/ASL2 - LANGIOCASES,16 CMA 006528 Page 41 (Review date 1 January 1987) TABLE 4G PLANT BARRY 1 UK 1 1 BURGHAUSEN | W GERMANY | i ST FONS | FRANCE | 1 BRIGNOUD | FRANCE | i SUNDSVALL | SWEDEN | NIAGARA 1 | USA I SPLIT 1 | YUGOSLAVIA! 1 MARL I W GERMANY | 1 START-UP 1948 1933 1939 1950 DATE LATENCY PERIOD OF ASL CASES IN SPECIFIC PLANTS(4-9 CASES) 1 9,17,18,28,31,33,18,19,18 1 11 1| I 17,21,22,25,24,13,21,32,30 I 11 1| | 21,28,29,37,38,27,41,34 | 11 I | 11,16,18,26,30,25,34 | | I1 1945 I 16,19,27,29,31 1 | 1 1947 I 15,17,21,23 1 I 1 1950 1948 | 20,20,22,23 I 1 | 15,16,22,21 1 1 | 1 1 | 1 1 NO OF CASES 91 1 1 9I 1 1 8I 1 1 7I 1 1 51 1 1 41 1 1 41 1 1 4I 1 AVERAGE PERIOD 21.22 years 22.77 31.88 22.85 24.4 19 21.25 18.5 WPX/ASL2 - LANGI0CASES.17 CMA 00652? Page ^+2 (Review date L January 1987) TABLE 4H LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT ________________(4-9 CASES) I YEAR OF I BARRY IBURGHAUSEN | ST FONS| BRIGNOUD SUNDSVALLI NIAGARA I SPLIT I MARL I FIRST EXPOSURE) UK | W GERMANY| FRANCE| FRANCE SWEDEN 1 USA 1 YUGO- |W GERMA.' | 1939 1 i I 1940 1 I I I1 I I 1 1 37,41 | 1 I SLAVIAI I1 I1 1 21 1 1 3I 1 1 1 38 | 11 11 1 41 1 I 51 1 1 61 1 I 71 1 1 8I 1 1 91 1 I 1950 131,33 1 I 1 128 1 1 1 1 29 1 1 28,34 1 I 1 | | 26,30 34 27* 31 29 19 1 1 1 15,23 1 1 1 1 1 17 1 1 1 1 1 1 I 23* 1 1 21 1 1 1 31 125,32 | 1 41 I 21 | I 5 1 122,24,30 ! 27 | 1 1 1 1 21 1 I 20 I 22* 1 I 22 1 61 1 | 7 1 1 17 1 81 1 I 91 1 I 1960 1 121 I 1I 1 1 2 1 18 1 1 21 | 1 1 1 1 1 1 18 16,25 11 11 I I 20 1 1| 1 1 115,16 1 1 1 21 1 3 1 17 1 I 41 1 1 1 1 16 1 1 1 I 5 1 19 1 1 11 11 1 6 19,18 1 1 11 1 71 1 1 11 1 8 1 18 1 1 1 91 1 13 | 11 11 I 1970 1 1 1 11 | 11 1 1 1I I 21 1 11 1 1 11 11 *Monomer worker WPX/ASL2 - LANGIOCASES,18 CMA 006530 Page 43 TABLE 5 (Review Date - 1 Jan 1987) Annual Incidence of ASL Cases (Date of Death) by Geographical Area 1955 7 1961 2 4 7 8 9 1970 1 2 3 4 5 6 7 8 9 1980 1 2 1983 1984 1985 1986 TOTAL 11 l Western Europe | North America I1 1 11 1 t1 1 11 1 11 1 11 11 1 |1 i1 |1 1 15 12 11 12 14 |1 11 14 13 t6 16 16 |7 |5 |6 |5 |1 |7 I5 |5 12 14 13 13 12 114 10 11 t3 12 1 12 1 | 73* ** j 44** 1 Rest of World | Annual Total 1 1l 11 11 11 1|2 11 15 13 12 13 15 3I 8 |5 1 | 11 2 I 11 19 1 | 10 |5 | 10 |5 12 1 10 17 15 12 8 I 125 | Cumulative | I Total ( Key Events 1 |1 12 13 14 16 17 1 12 1 13 1 17 j 20 1 25 1 33 I 38 | 49 I 60 t 69 1 79 I 84 | 94 | 99 I 101 lilt 1118 | 123 | 125 1 1 1 l 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 | Viola 1 1 | Maltoni | Goodrich 1 1 1 1 1 1 1 1 1 1 1 l * Includes G03 aerosol can filler but omits It 01 bag extruder ** Does not Include US33, and 36, FI 5, G31 and 32. All still alive. WPX/ASL2 - LANGIOCASES,19 r *S 9 0 0 TABLE 6 Page 44 (Review date 1 January 1987) ASL CASE NUMBERS BY YEAR OF DEATH AND GEOGRAPHICAL LOCATIONS (EXCLUDING IT01) 1 KEY 1 1 EVENTS 1 | WESTERN EUROPE 1 | NORTH AMERICA 1 1 REST OF WORLD 1 11 1 11 1 1955 1 Cl 1 16 17 1 | C2 1 1 18 19 1 1960 11 12 13 14 15 1 1 1 I US8 I C3 1 I US5 1 1 1 1 1 1 1 1 Cz2 1 16 11 1 7 1 FI 11 18 | C4,C5,US4,US7,US10 1 1 9 1 G1 I US12.US16 1 |Viola 1 1970 1 Swl I US11 1 1 1 1 G2 | C6,US2 1 1 2 1 N1 ,Sw2,UKl,It2 1 C7 1 IMaltoni 1 3 1 G3** * I C8.US1.US3.US23 1 Yl.Y2-.Czl I Goodrich 1 4 ! G4.G5.UK3 1 C9.US13 1 5 1 F2,F3,G6,G7,G8,It3 | US6,US9,US18,US26 1 Japl 1 6 1 Bl,F4,F5,F6,F7,Sw3 | US19.US20.US22, 1 Jap2,Y3 1 7 1 F8,F9,G10,Gll,G12,Sw4 | C10.US21.US24* 1 1 8 1 F10,F11,G9,G13,G15 | US27.US28 1 Y4 1 1 G16.G17 1 1 1 9 1 F12,F13,UK4,UK5,G18 1 1 1 1980 1 UK6, UK7,G19,Sw5,G20,G21US | US17, US29, US30.US32I 1 1 1 It4,F14,UK8,G22,G23 1 1 1 2 1 G26 | US31 1 1 3 | UK09,It5,F17,B2,G24,G25,G30| US35, US34, US38 1 1 4 | UK10, F16, F18, G27.G29 | US37.US39 1 1 5 1 UK11, UK12,F19,F20,G28 1 1 1 6 1 F21.UK13 1 Total 1 73*** 1 1 44*** 1 18 1 11 * Cholangiosarcoma ** Aerosol can filler *** Does not include US33 and 36, F15 and G31 and 32. All still alive. WPX/ASL2 - LANGI0CASES.20 CMA 006532 Page 45 TABLE 7 (Review date 1 January 1987) ASL CASE NUMBERS BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION (EXCLUDING IT01) KEY | EVENTS | 1 | WESTERN EUROPE 1 1 NORTH AMERICA 1 I REST OF WORLD| II 1 1 Viola 11 1 1 1 1939 1 1 US24* 1 1 40 1 1 I 1 1 |Frl1,Frl6 1 C3.US27 1 1 21 1 US13, US29 1 1 3 1 Frl 4 1 C2.US19 1 1 4 I UK1 1 Cl ,C5 ,US5,US7,US28,US3 5 1 I 5 I Sw2 1 C4,US3,US9 1 1 6 1Frl,Fr3,Sw4 1 C7,C9,US8,US11,US21,US31 1 1 7 1 Sw3 1 C6.US22.US26 1 1 8 IFr9, Frl7 1 US1 1 1 9 1Frl2,Fr4 1 US12 1 1 50 1Fr7,N1,UK8,UK9 1 US16 IY2, Cz2 1 1 1Swl,UK5,Fr20,G30 1 US10, US32 1 1 2 |G3** 1 US4 1 1 3 |G15,It3,G26,G31*** 1 CIO, US37 1Japl.Yl 1 4 |G7,G8,UK4,G19 1 US18.US33*** 1 Y3 1 5 f Gil.G16.G18, Frl5*** 1 US2.US17.US20.US34 1 1 IG23.G28.G32*** 1 1 1 6 IFR10.G1 1 US36*** 1 1 7 |Fr8,G4,It2,G2,UK12 1 I Czl 1 8 IFr6 ,B1 1 US23 IJap2,Y4 1 9 1Fr2,It4,Frl9,Fr21 1 1 1 60 |G5,G13,G25,G28 1 US39 1 1 1 |G9,G10,G12,G17,G20,G22| C8 1 1 2 |G6,UK6,G21,B2,G29 1 US6 1 1 3 IFrl3, UK7,Frl8 1 US38 1 1 4 1 Sw5 1 US30 1 1 5 IFrS.UKll 1 1 1 6 IUK3, UK10 1 1 1 7 I It5 1 1 1 8 IUK13 1 1 1 9 IG24 1 1 | 70 1 1 1 1 2 1 Maltoni | 31 1 11 1 11 1 1 Totall7 6 1 1 46 11 18 | 1 11 1 11 * Cholangiosarcoma (US24) ** Aerosol can filler (G3) *** US33 and 36, Frl5 and G31 and 32 are still alive. WPX/ASL2 - LANGIOCASES.21 CMA 006533 t\j *ir*v - (Review date 1 January 1987) TABLE 8 WESTERN EUROPE FVC PRODUCERS - START-UP DATES vs ASL GASES ((KITTING (D3 6. It.01) START-UP| COUNTRY NMC | COMPANY NAFE I LOCATION I ASL CASE HUBER I YEAR OF | YEAR 1931 1933 | IWest Germany IWest Getneny 1 I BASF |Wacker 1 I Ludwigshafai IBurghausen 1 I 1st Exposure | 11 | 104,07,11,15,23,24157,54,55,53,55,69,60,531 1938 1939 1940 11 I Italy IMontecatini I France |f&ione Poulenc/ 1 IAtochan I United KingdanI ICI I United Kingdom|ICI 1 I Acna |St Eons 1 |Runcorn IHillhouse 125,31,32 1 103,09,10,11,14 115,16,17 1 101,04,12 |55 1 146,48,56,41,43, 155,41,48 1 144,54,57 | | | | 1 | 1945 I Sweden IKsnanord |Sundsvall(Stockvik) 101,02,03,04,05 151,45,47,46,64 | 1946 | Switzerland 1 |France ILonza/ICI since|Sins 11982 | | Rhone-Poulaic IRousillon 1 1 101 1 1 146 1 1 | 1947 1948 I Italy | Montedison lUnlted Kingdom|BP Chen/ICI | |since 1982 IWest Germany iCWl/Huls | Porto Maighera I Barry 1 Itferl 102 157 103,05,06,07,08,05 166,51,62,63,50,50 110,11,13 166,65,68 109,10,26,29 161,61,53,62 | 1 | | 1949 IBelgiun ISolvay IJemeppe 101,02 158,62 | 1950 |France | PCUK/Atochon IBrignoud 102,04,05,06,12,15 159,49,65,58,49,59,51 | 1 |France 11 |Rhone-Poulenc I St Auban 120 107 1 150 1 I I Holland I Norway I Shell I Norsk IPernis IHeroya 1 101 1 150 1 | 1951 1952 1953 I Italy I Italy lAistria |France | Montedison I Montedison IHalvic |Solvay |Brindisi ITerni IHallein ITavaux 1 1 108,13,18 1 1 157,63,63 ' 1 1 | 1 Italy ISolvay |Ferrara 103 153 I I Spain |Rio Rodano I United Kingdom! BIP IWest Germany IHoechst IHernani lAycliffe IGendorf 1 1 118 1 1 155 1 1 | 1954 IWest Germany IDynanit ITroisdorf 101,02,08,12,16,17 156,57,54,61,55,61, | 1955 1956 1958 1960 1 1 Spain 1 Spain 1 IWest Germany I Italy 11 | Monsanto Iberia IMonzon |Caiqsa I Sabirenigo IHispavic ITorrelavega ISolvay lEheinberg IS C Ravenna |Ravenna 119,20,21,22,27.3C 154,61,62,61,55,51 11 11 11 11 104 159 1 1 1 1 1 1 IWest Germany ILonza/ICI since IWaldslut 106,13,28 162,60,60 1 1962 1965 1 IPomwal |France 11982 Idres I fflicne-Poulenc ! |Oporto IMontlucon 1 1 121 1 1 159 1 1 1 1966 1 Italy IWest Germany IWest Germany IPozzl IWacker IHoechst iFerrandina 1 I Cologne I |Knapsack( Frankfurt) 105* 1 1 160 1 1 1 1967 I France 1 Spain I Greece |AIO Chiade |Rio Rodano |Esso Pappas IBalan I Miranda de Ebro IQlavata Salonika 1 1 1 I 1 1 1 1 1 1968 1969 IBelgliin IBadiphil I United KLradanlVinateic I Italy IRunianca I Antwerp IStaveley ICapllari Sardine 1 1 1 1 1 1 1 1 1 1970 1 Italy | SIR I Porto Torres Sar 1 1 1 1971 1972 I United KipgdanllCI I Italy |S C Ravenna I Spain IHispavic |Sweden IKemanord I United KingdomIBP Chen I Finland IPekana IRuncom |Ravenna IMartorell | Stervmgsund 1 Raglan Bay ISvartback 1 1 1 1 1 1 11 11 11 11 |1 I Crm 006534 1976 1977 I Holland |France 1 Spain IDS! IBeek Limburg ISoc Art D'vinyl IMazlngarbe | Monsanto Iberia|Tarragona 1 1 1 ! | 1 1 1 * Laboratory worker in Research Departmert K4i w a <%->* , v4<vJ ^f> no ^j,,a yy^f- Vtvt*H*rf ct-arf nt> dat-o nf t+ip Pi anf . TABLE 9 Page 47 (Review date 1 January 1987) USA PVC PRODUCERS - START-UP DATES vs ASL CASES START-UP| COMPANY NAME 1 LOCATION I ASL CASE | YEAR OF | YEAR | 1 1 NUMBER I 1st EXPOSURE | 1939? |*UCC 1 S Charleston 107,13,19,21,24, 144,42,43,46,39, I 1 1940? | *BFG 1 I Louisville 127,28,29,31,35 141,44,42,46,44 | 101,02,03,04,05, 148,55,45,52,44, | 1 1 106,09,16,17,22, 162,45,50,55,47, | 1 1946? |*UCC 1947 I Goodyear I 126,33,34,37 147,54,55.53 | Texas City (Partially closed 1977) 1 ! Niagara Falls 108,10,11,20 146,51,46,55 I 1 I 1948 | Firestone/ | Pottstown 112 149 I 1950 | Occidental | Uniroyal 1 | Monsanto | | Painesville 1 (closed 1975) | Springfield 1 1 1 132 1 1 I 151 1 I 1 | 1 1 (Closed 1975 1 1 1 1952 | Dow I BFG | Midland (No PVC since c 1975) 1 Avon Lake 1 18 1 154 1 | 1953 I BFG 1954 1 General Tire 1 Deer Park (Formerly Diamond) | Ashtabula 136 1 156 1 | 1956 ! | Air Products 1 (Closed 1984) | Pensacola 1 1 | Atlantic Refining | Brooklyn(Closed late 1960s) | Borden | Leominster (Closed 1984) 1 1 1 1 1 1 | Conoco 1 Hebronville (Closed 1975) 1 "* | I BFG 1 Niagara 1 1 1 I Great American | Fitchburg 123 158 | I Plastics | Hooker | Pantasote | (Closed 1983) 1 | Hicksville (Closed 1980-81) | Passaic(Closed 1984) 39 1 1 160 1 1 | 1957 I Atlantic Tubing | Tenneco | Cranston (Closed 1967) | Flemington NJ 130 1 159 1 I 1 1958 | Keysor Century 1 (Closed 1985) | Saugus, Cal ! I 1 1 1 1 1960 I BFG 1 Watson, Cal 1 1 1 | Air Products | Calvert City |38 163 I 1 I Borden 1 (closed March 1982 Re-opened October 1983) | Illiopolis 1 1 1 1 1962 | Tenneco/Occldental| Burlington NJ 1963 | Conoco/Vista | Aberdeen, Miss 1 1 1 1 1 1 I Stauffer 1965 I Conoco | Long Beach, Cal (Closed 1982) 1 **| Assonet, Mass (Closed by Olin 1975 , see below) I | 1 Ethyl | Baton Rouge (Closed 1984) I 1 1966 1 Georgia Gulf | Delaware City (Formerly Diamond) 1 1 IGen Tire/Pantasote | Mt Pleasant W Va |(Closed 1982) 1 1 I BFG I Henry, 111 1 1 1 I Stauffer | Delaware City (Sold to Formosa 1983) 1 1967 | Allied ***| Painesville, 0 1 1 I 1 1 (sold to Robintech) | Hooker/Occidental | Burlington NJ I 1 | 1 1 1968 I Firestone 1969 I BFG 1 Perryville (Closed 1982) 1 Pedrickton NJ 1 1 CMA 00653 1 | Goodyear I Olin 1 Plaquemine 1 1 **l Assonet, Mass (Closed 1975) (See a bove) 1 I | (Formerly Conoco)| 11 I 1971 I Conoco/Vista | Oklahoma City 1 1 1 WPX/ASL2 - LANGIOCASES,23 Continue d Page 48 TABLE 9 (Continued) USA PVC PRODUCERS - START-UP DATES vs ASL CASES |START-UP | I YEAR 1 I 1972 1 I 1973 1 1 1 1 1 1 I 1974 1 1 1 1 1975 1 1 1 1 1979 1 1 I 1983 1 COMPANY NAME 1 Nat Starch Borden Robintech *** 1 1 1 | 1 1 1 1 Atlantic Tubing/ | Tallyrand | Shintech | Certain-teed | Georgia Pacific | Tenneco/Occidental| Firestone/ | Occidental | Formosa | LOCATION | Meredosia, 111 1 | Springfield | Painesville, 0 | (sold to Georgia | Pacific who | converted to | polystyrene) | Cranston RI (Closed Freeport, Tex Lake Charles Plaquemine, La Pasadena, Tex Plaquemine 1 | | | | | Point Comfort, Text ASL CASE NUMBER 1982) 1 YEAR OF | 1 1st EXPOSURE | 1 1 1 1 1 1 1 I 1 I 1 1 1 I 1 1 * My databank has no information on UCC before 1946 or BFG before 1950 ** Refers to same plant at Assonet ***Refer to same plant at Painesville. Allied plant never operated again for PVC after it was sold to Robintech. NB Some of the plants in this list were closed down, some have changed ownership over the years, some have changed their product. WPX/ASL2 - LANGIOCASES,24 006536 Page 49 TABLE 10 (Review date 1 January 1987) CANADIAN PVC PRODUCERS - START-UP DATES vs ASL CASES | START-UP I I YEAR COMPANY NAME 1 LOCATION 1 I ASL CASE I NUMBER 1 YEAR OF 1 1st EXPOSURE I 1943 I Goodrich 1(1941?) 1 1 Shawinigan 1 11 101,02,03,04,05 | 44 ,43,41,45,44, 106,07,08,09,10 14 7 ,46,61,46,53 1 11 I 1951 | Monsanto 11 1 La Salle (Closed 1975) 1 1 1 11 I 1957 I Goodrich 1 1 Welland 1 1 ! 1 1 11 1 1966 I Esso 1 1 Sarnia 1 1 1 1 1 11 11 I 1979 | Diamond Shamrock Alb 1 Fort Saskatchewan 1 1 1 11 WPX/ASL2 - LANGIOCASES.25 CMA 006537 Page 50 TABLE 11 (Review date 1 January 1987) EASTERN BLOC PVC FACTORIES - START-UP DATES vs ASL CASES |START-UP I COUNTRY NAME | COMPANY NAME I YEAR 1 1 |Pre 1939 I East Germany I State Company 1 1941 I Russia |State Comps 1 1950 I Yugoslavia IJugo Vinil 1 1951 I Czechoslovakia |State Comps 1 1955 I East Germany |State Comps I 1956 I Rumania |State Comps I 1957 I Poland |State Comps I Rumania |State Comps 11 1 1958 I Rumania |State Comps 1 1959 I Hungary I State Comps 1 1961 I Rumania I State Comps 1 1963 I Yugoslavia lOhis 1 1965 I Bulgaria |State Comps I 1967 I Poland |State Comps 1 1969 I Russia I State Comps 1 1970 I Rumania I State Comps |Russia I State Comps 1 1972 I Yugoslavia IVinilplastika 1 1975 |Czechoslovakia!State Comps I Russia I State Comps I 1976 I Yugoslavia 1 Hip 1 1977 |Rumania |State Comps | LOCATION 1 ISchopau |Vladimir et al 1 Split |Novaky |Bitterfeldt |Icechim lOsweicim (Dwory) |Tirnaveni |Turda |Risnov iBerente Borsod |Borzesti !Skopie I Varna |Tarnow I Djer.linsk IRimnicu Vilcea |Volgograd 1 Zadar |Neratovice IKalush Area |Pancevo |Rimnicu Vilcea | ASL CASE 1 NUMBER 1 1 101,02,03,04 101,02 1 1 1 1 1 1 1 1 1 1 k 1 1 1 ! 1 I 1 1 1 YEAR OF 1 1st Exposure 1 I 153,50,54.48 157,50 1 1 1 1 1 1 1 1 1 !......... 1 1 | 1 ! 1 1 1 WPX/ASL2 - LANGIQCASES,26 CMiA 006538 Page 51 (Review date 1 January 1987) TABLE 12 JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES | START-UP| I YEAR 1 I 1950 1 1 1 I 1951 1 I 1952 1 1 I 1951 1 1 1 I 1955 1 1 1956 1 1 1 1957 1 1 I 1960 1 1 1 1964 1 1 1966 1 I 1967 1 1 I 1968 1 1 I 1970 1 1 1 1 1 1 1 1 1971 1 1 1973 1 I 1974 1 | I 1975 1 1 I 1977 1 COMPANY NAME Chisso Corp Kanegafuchi Kag Tek.Ro aha Mitsui Toatsu Mitsubishi Mon Sumitomo Kag Denki Kagaku Nippon Zeon Toa Gosei Ryo-Nichi Nippon Zeon Nisshin Kagaku Kureha Kasei Shinetsu Kag Denki Kagaku Kanegafuchi Kag Chisso Corp Tokuyama Seksui San Arrow Kagak Sumitomo Kag Ryo-Nichi Shinetsu Kag Chisso Corp Denki Kagaku Kanegafuchi Kag Kawasaki Yuki Mitsui Toatsu Nissan Kagaku Shinetsu Kag Tekkosha Asahl Glass Toyo Soda Central Kagaku Toyo Soda Unknown 1 LOCATION 1 | Minamata 1 Osaka | Sakata 1 Nagoya I Yokkaichi 1 Kikumoto 1 Shibukawa 1 Kambara I Tckushima 1 Uozu | Takoaka | Takeo 1 Nlshiki 1 Naoetsu 1 Ohmi | Takasago | Chiba 1 Tokuyama I Tokuyama 1 Chiba | Mizushima | Tokuyama | Mizushima I Gol (Chiba) | Kashima | Kawasaki | Sakai | Chiba I Kashima | Yokkaichi 1 Hayatsuki | Sakata I Yokkaishl | Kawasaki | Yokkaichi | Kashima I ASL CASE 1 NUMBER 1 1 1 01. 02 i 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 I YEAR OF I 1st EXPOSURE 1 1 1 1 53, 58 1 1 1 1 1 i 1 1 1 1 1 ! 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 * tjvy/ A c;t t ANOTOCASES.27 CMA 006539 < 1 i Page 52 (Review date 1 January 1987) TABLE 13 SOUTH AND CENTRAL AMERICAN PVC PRODUCERS I START-UP1 COMPANY NAME I YEAR 1 1 1953 | Monsanto Mexica 1 1954 | Policyd I 1955 | Geon Do Brazil 1 1956 | Elchlor I 1960 I Electrochlor | Viplastic 1 1961 | Indupa I 1965 |(SOC Paramanga 1(1967 start up | PET Columbiana I 1966 I Carburo De Col I 1967 | Plasticos Omega I 1968 | Primex I 1970 | Policasa I Petro Dow 1 1971 | Polimeros Mex 1 1975 | Rico Chemicals 1 1976 I Petroplas I 1977 | Indust Resistoc I 1978 | Huls Brasil I Polychem I Policyd 1 1979 | PET Camacari I LOCATION | I| | Lecheria (Mexico) | | Mexico City (Mexico) | | Sao Paulo (Brazil) | I Sao Caetano (Brazil) | ICapitan Bermudez(Argentina)| I Mendoz (Argentina) | I Cinco Saltos (Argentina) | I Paramonga (Peru) | ) I Cartagena (Colombia) | Medellin (Colombia) 1 | | | Mexico | | Puebla (Mexico) | Managua ^Nicaragua) | | I Conception (Chile) 1 I St Martin Puebla (Mexico) | | Guyanilla (Puerto Rico) | I EL Tablazo (Venezuela) | I Tlazcala (Mexico) | | Cubato (Brazil) | | El Salvador | | Coatzacoalcos (Mexico) | I Camacari Bahia (Brazil) | ASL CASE NUMBER I YEAR OF I 1st EXPOSURE 1 1 1 1 1 1 I 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 WPX/ASL2 - LANGIOCASES,28 CMA 006540 Page 53 (Review date 1 January 1987) TABLE 14 AUSTRALASIAN PVC PRODUCERS START-UP DATES START-UP | COMPANY NAME YEAR | 1 Mid 1950s | ICI Australia 1 1960s | B F Goodrich 1 Late 1970s| ICI Australia i i | LOCATION | | Botany, Sydney | | Melbourne | | Laverton | Melbourne | | ASL CASE NUMBER 1 YEAR OF 1 1st EXPOSURE 1 1 1 1 1 1 1 1 WPX/ASL2 - LANGIOCASES,29 0065-41 Page 54 (Review date 1 January 1987) TABLE 15 MIDDLE EASTERN PVC. PRODUCERS START-UP DATES START-UP 1 COUNTRY NAME DATE 1 1 Sept 1986 1 Saudi Arabia 1 1 1 1 1 1 1 COMPANY NAME 1 11 LOCATION 11 I National Plastic |Arabian Petrochemical Company | Company IMadiant I (Ibn Hayan) !Al-Jubail 1 |Al-Sinahyah 11 11 11 WPX/ASL2 - LANGIOCASE S,30 CMA 006542 Count ry ICl CHEMICALS 4 POLYMERS CROUP LIVER Angiosarcoma Cases (Review Date: l Jan 19..) ii 1 12 1 JL 11 |COUNTRY AND NAME OR l REFERENCE |INITIALS! HO i i JL i 3i j_ i DATE OF 1 BIRTH i i i iti ii 1I ii A i s t * | 7 i e 1 9 1 10 I 1 ( 12 i n i 14 i n i _L j J JL i 1 lt1 |YEARS OF l I IHISTO- i i t | |l FIRST VC (DATE OF I ACE AT J EXPOSURE YEARS 0P| DATE OF LOGICAL (ESTIMATED! i 1 |OTHER i 1 | COMPANY I FACTORY |EXPOSURE (DIAGNOSIS! DIAGNOSIS! TO (EXPOSURE! DEATH Iii |DIAGNOSIS] | tCONFIRM-! EXPOSURE (OCCUPATION (CAREER j |ATION (LEVEL (HIGHLIGHTS] tjj A J___________________J1 WPX/ASL - LANGlOCAStS, j 16 OTHER COMMENTS n > o o cn ui