Document 06RjE1Zm4aGpggeMDV7R5n2kJ

mm ISTAI1.I&MCC B Z E . 1. d u P o n t d e N e m o u r s S C o m p a n y IN CO R PO R A TED W i l m in g t o n . D e l a w a r e 19898 POLYMER PRODUCTS DEPARTMENT EXPERIMENTAL STATION perso n al A io c o n f id e n t ia l cc : A . J . Dahl - 353 . V.\ Karrh - U l l - i O O L. J . Papa - 2C 9 Pral Pile I .C . !&! iO - Ja n u a ry 1, 1932 TO: FROI D S . Y . L . PONI - P P D , P a r k e r s b u r g S . S . STA-fo r : A N A LY SIS OF BLOOD SAMPLES FOR PEP.FLUOROOCTANOATE ( J o b N o . 8 1 0 -5 7 8 ; PRAL N o s . 8 1 - 6 0 0 6 - 6 0 3 3 ,81- 61)48- 6162, ______________N o te b o o k N o s . E 2 7 ^ 3 3 ,E 2 6 2 3 8 ,E 2 7 i+ 3 2 )_____________________ As req u ested in your le t t e r s o f 12/15 ana 12/29/31 to L . J . P apa, th e I t b lood sam ples su b m itted then have been a n aly zed fo r p e rflu o ro o cu a n o a te (Cg) by th e u s u a l gas ch rom atog rap h ic method ES-567- R e s u lts and sam ple id e n t if ic a t i o n are giv en in The a tta ch e d t a b le . Attachm ent ja h Key W ords: P erflu orooctan oate GC Blood A n a ly sis There s a world ol thing?, wp re doing something about 000186 EXP000077 EID713891 TABLE I CONCENTRATION OF PERFLDOROOCTANOATE IN BLOOD (a) Sample PRAL No Sl-600c 81-6007 81-6008 8 1 - d OOQ 61-6010 61-6011 51-6C12 81-6C13 6I - 6C I I 81-6015 81-6016 81-6017 81-6018 81-6019 Sl-6020 Sl-6021 31-6022 81-6023 8l-6022 81-6025 81-6026 81-6027 81-6023 81-6029 81-6030 81-6031 81-6032 81-6033 81-6032 Date Sampled 12/1/81 12/1/81 12/1/81 12/1/8: 12/2/ c l 12/2/61 12/2/81 12/3/81 12/3/81 12/3/81 12/2/81 12/ 2/81 12/7/31 12/7/Sl 12/7/81 12/7/81 1 2 /7/32 12/8/81 1 2 /8/31 1 2 /8/31 12/9/81 12/9/81 12/9/81 12/9/81 1 2 /10/51 12/U/Gl 1 2 /11/51 12/12/81 12/12/61 P .R.No . W.S. v;. s . W.S. 656 2755 3869 3737 W.S. 3092 760 2756 2029 3228 U312 W.S. W.S. W.S. W.S. 3022 W.S. 3295 2706 2015 3621 2523 1816 927 3962 3352 Name GC A n a l y s i s _____________(b) Date Analyzed [Cr ], bg F/g blood 12/21/81 0.16 12/21/81 Sc 1/5/82 0.50 12/21/81 0 . 3* 12/21/81 0.0-6 1 2 /21/31 0.011 12/22/81 2.8 12/22/81 0 .36 1 2 /21/31 0 .1 5 12/22/81 1.2 12/22/81 O.iS 1/5/82 0.021 1/5/82 0.82 1/5/02 0 .C'l 1/5/82 & 1/8/82 0.36 1/5/82 0. Oco 1/5/82 0.12 1 /5/32 0.13 1/5/82 0 .039 1/5/82 0.21 1/5/82 0 .3 6 1/6/82 c. oSC 1 /6/32 0 .6 1 1/6/82 & 1/8/62 1.8 1/6/82 & 1/8/62 _L. J. 1/6/32 1 1 /3/82 - 1 /6/32 0.21 1/6/82 0 ,f*9 1/6/82 0.O 1/6/82 0.2-J *REDACTED* EXP000078 EID713892 000187 TABLE I CONCENTRATION OF FERFLUOROOCTANOATE IN BLOOD (a) Sam ple FRAL No. 31- 61U8 81-61*49 Gi-6150 81-6151 El- 6 1 5 2 51-6153 6 l-6 l5^ 81-6155 81-6156 81-6157 81-6158 81-6159 81-6160 81-6161 31-6162 Date Sampled 12/15/81 12/16/61 12/17/81 1 2 /17/&1 12/17/81 1 2 /17/61 12/18/81 12/18/81 12/18/81 12/lS/Si 12/18/61 12/21/81 12/21/81 12/21/81 12/23/61 P.R.No. 1850 4106 4)493 W. S . K.S. 37 *4 1698 4720 W.S. 3383 3611 W. S . W.S. W.S. 1959 Kane 61-1872 1 0 /7/81 4720 GC Analysis___________________{b) Date Analyzed [Cr ], pg F/g blood 1/6/82 0.22 1/7/82 1.6 1 /7/32 0.51 1 /3/52 0.?1 1 /7/32 C. 03 * 1/7/82 0 .8 5 1/7/82 0 .6 3 1/7/82 0 .0 9 9 1/7/82 0 . 1*4 1/7/82 0 .2 3 1/7/82 0 .1 7 1 /7/82 & l/S/62 0.092 1/7/82 0 .0 2 7 1/8/62 1.0 l/S/62 0 . 3*4 1/8/82 0.035 (a) A n a ly s is as d e scrib e d in Lab p a c k e d colu m n GC a n a ly s (b) A lthough the a n a ly s is is s p e c ific a lly fo r p e rflu o ro o cta n o a te (acid or s a l t s ) , c o n c e n t r a t i o n s a r e g iv e n in ppm f l u o r i n e f o r c o m p a r is o n w it h t h e r e s u l t s o f t o t a l o r g a n i c f l u o r i n e a n a l y s e s . (ppm F = 0 .6 8 8 x ppm p e r f l u o r o o c t a n o i c a c i d ) E s t im a t e d u n c e r t a i n t y i s 10% r e l a t i v e s t a n d a r d d e v i a t i o n . The lo w e r l i m i t f o r q u a n t i t a t i o n i s 0 .0 0 7 p g F / g . The d e t e c t i o n l i m i t i s 0. 00*4 h g F / g , b u t co n ce n tra tio n s in th a t range cannot be w e ll q u a n tita te d and are rep o rted as < 0 .0 0 7 - hone d e t e c t e d ( n . a . ) i s r e p o r t e d f o r s a m p le s w it h [ e g ] < 0 . 00*4 ppm, w hich cannot be d is tin g u is h e d from re a g e n t b ackgro u nd . (c ) P r e v io u s ly a n a ly se d sam p le, re a n a ly se d fo r com parison w ith rep eat sam ple 81- 6 15 5 ; r e s u l t o f t h e o r i g i n a l a n a l y s i s (10/26/81) was C.0 3 9 . REDACTED* 000188 EXP000079 EID713893