Document 068yLbqbX0LeBRd23LebvxLwd

SXfg&XSEHUL HOBS. ~ SAB&SAC XABORATCBY grinding Dust Bxpoeure on laboratory Animals December 24, 1946 Hr* I* Dunn* Treasurer *ew York Office ' Enclosed herewith is a report covering the first 10 soothe of our experimental work which Dr* Gardner wae doing for us at Saraaao Lake* You will note that in mih of the groups of animals exposed to duet ora* an 8 to 10 month period* the findings as far as production of fibres is in the lungs is concerned, are essentially negative* In other words the experiment thus far warrants a tentative conclusion that the &st exposure in our grinding operations while producing changes observed in'the x-ray fils is a relatively inert dust* This substantiates ^ original impression that the nodulations we have seen are not due to true silicosis but are similar to the changes observed In lunge of "persons exposed to iron dust* It is of course too soon to draw any definite oonolusions but the Implications are very encouraging and very . satisfying to me After we have had a ohanoe to observe the results, over the next period of months X feel that we will be in a position to definite!^ state that ws are not dealing with silicosis but a non-disabling si&erotis* ; . You will also note Paragraph 4 which so far indicates that theauimels whioh_J; have been infected with tuberculosis and then dusted show no appreciable dlffereac** In other words the spread of infection it apparently not accelerated by the initiation of this dust during the 8 months' period study* .. 1 1 feel that we should consider the money spent in this experimental work to be a very definite contribution to our knowledge of dust diseases and one that I think will have far reaching effects not only as far as Brake 8hoe is oonoerned but through the industrial world in general* I think that you and Hr* Given and others doaosrued in making this experimental work possible deserve a great deal of credit for war foresight end cooperation in making this study possible* Whsn theexperimentsiwork has been completed, 1 plan to write it up In detail and publish the story* This will not be, of course, for some months yet "to*.nothing will be published without your approval* X will let you know as soon as we have any more results* lH<np Enclosure L* S* Hamlin, H*P . Medical Director * SPNY 000434