' further to our Meiaorandum 34254 of 11,8*43 we now enclose-* One copy of Lead Poisoning - Preliminary Medical Beport and One copy of Details of Cases of Lead Poisoning Abadan 1942, '.

The Health Department had a record of thirty-one cases of lead poisoning of children in 19^8, four of v.iion died.

*'* v, June X5* 193S yA%n~i fi-V* H *` Dr, E* W# Russell X Rue Toussoun Alexandria# Egypt Dear Doctor Russells I have just received word from Mr, F, M* S, Tegner of Ethyl Export Corporation that you are willing to undertake the medical super** vision of workmen who are soon to be engaged in mixing Ethyl Fluid with gasoline for the Vacuum Oil Company in Alexandria, Accordingly I am sending you herewith a small pamphlet which outlines the general policies which we have attempted to carry out and which give seme brief statement of certain of the problems which are to be met, I consider it very unlikely that you will have any difficulties ih connection with this work since we have found that If the equipment is satisfactory# and if It Is operated properly# no illness or Injury of any kind occurs* On the other hand, I can not strees too much the importance in my mind of having our medical representatives check the equipment and the manner of its use from time to time to see that carelessness does not creep into this apparently safe operation* The Fluid Is a definitely poisonous material and if It is handled carelessly# serious cases of poisoning will develop* The gasoline, on the other hand, has demonstrated its entirely safe properties from the point of view of lead, and it is ray opinion that the'gasoline treated with lead in proper concentrations is no more dangerous rtd handle than is ordinary gasoline* We have attempted to prevent all lead poisoning in connection with mixing operations by keeping a sharp lookout for: signs of lead absorption in the mixing personnel and also, as I have indicated previously, by making a critical survey of the mixing equipment and its means of operation from time to time* Our supervision of the workmen has consisted of periodic careful physical examinations,plus microscopic examination of blood smears regularly, In this Country we have also made It a point to study the lead excretion of workmen from time to time so as to be certain of the magnitude of the lead exposure* We know hew that if the mixing equipment Is operated In accordance with the instructions, no measureable lead absorption occurs* Moreover no cases of lead poisoning have been seen In connection with this work ever the entire period of years In which the present type of medical and mechanical regime has been in oporation# KfT 0013o v a * 2 la connection with the use of leaded gasoline# there may be some apprehension on the part of people in your vicinity and there may be complaints of various kinds* Despite the negative character of our findings up to the present* we have made it a point to investigate these complaints with all care#and I suggest that it would be advantageous if you were to do likewise* I think you will have very little difficulty from this source* but If difficulties of any kind So arise# I should appreciate It very much if you would communicate with me concerning them so that I will be informed as to what is occurring* In view of the problems which have been associated with this industry# and in view of the extensive experimental work which has been done in evaluating these problems* there are a considerable number of published articles which, deal with various phases of the subject* I shall send you copies of such of these articles as are now available for your Infor mation# and as soon as I am able to obtain it* I shall send you a copy of a volume in which we have assembled all of the articles which bear upon this subject.

What are early symptoms of lead poisoning from ethyl gasoline?

He and many others continue to speak of "chronic" lead poisoning in the same breath in which they talk about acute episodes of intoxication.

At present, however, I insist upon having samples of blood for analysis in all cases of childhood lead poisoning, and in all cases of lead poisoning in the adult, except those rare cases of tetraethyl lead poisoning which occur under highly unusual or accidental cir cumstances (when tetraethyl lead is absorbed, the blood level increases little or none, apparently because the intermediate compounds resultant upon the de- ' composition of the molecule in the tissues are r.ot capable of combining with the component of the crytlirocyte that is involved when inorganic lead compounds are absorbed).

Most of these have arisen from the fact that the illness of the claimant had not been studied properly and that proper diagnosis had not been arrived at. @ have never seen a case of lead poisoning as the result of contact with or the handling of leaded gasoline.

ETH YL GASOLINE AND LEAD POISONING New uses for many substances, in this instance lead, are continually being discovered.

Q-6: Didn't one of the originators of tetraethyl lead die of insanity caused by lead poisoning?

There are quite a number of other articles on var.ioua phases of the problem of load absorption and the diag nosis of lead poisoning, which have not been translated from the English, and which I can send you, if you are in terested.

Q-6: Didn't one of the originators of tetraethyl lead die of insanity caused by lead poisoning?

, i- . 2 - '' t j^cm^tti above information X believe you will . recognise that a claim for lead poisoning as the result of taking small amounts of gasoline into the month is in the very nature of the ease ridiculous.

Proposed regulation 191.5 would allow the unrestricted use of lead at concentrations of 0.5 percent of the dried paint film even though lead is a cumulative poison and has caused deaths or toxic symptoms in children who have eaten paint films containing lead.

Proposed regulation 191.5 would allow the unrestricted use of lead at concentrations of 0.5 percent of the dried paint film even though lead is a cumulative poison and has caused deaths or toxic symptoms in children who have eaten paint films containing lead.

They appear to have no parallel among cases of industrial lead poisoning, and nearly all writers on lead poisoning where the eves are implicated, have had experience of industrial lead poisoning only, and of that in adults.