A governmental Commission,having issued a report on tetraethyl lead (confirming our findings for local consumption), is in no hurry (understandably) to take any further action, and so there will be David E.

For this reason, I believe that such people as the Vacuum Oil Company would remonstrate against the inability to use any tetraethyl lead although we will be glad to issue regulations to the effect that no lead shall be so used if you feel that it is necessary.

MaeshXe has told me that he talked over with you the question of information which should be made available to the Harbor- authorities In Hamburg as to the exact nature of the dangers associated with the handling of tetraethyl lead.

They do not particularly wish to work against each other by attempting to demonstrate that their gasoline is better than competitive leaded gasoline and, therefore, about all that is left for them to demonstrate is the effective ness of tetraethyl lead as an anti-knock thus working for all customers against the Shell who are opposing the use of lead in any form# For this reason, I believe that such people as the Vacuum Oil Company would remonstrate against the inability to use any tetraethyl lead although we will be glad to issue regulations to the effect that no lead shall be so used if you feel that it is necessary* The Vacuum Oil Company has bought two demonstrating engines (l-Australiaj lNew Zealand) whioh may give some idea of the amount of this sort of work that goes on.

A governmental Commission,having issued a report on tetraethyl lead (confirming our findings for local consumption), is in no hurry (understandably) to take any further action, and so there will be KE 0009262 David E.

ETC 00101 TETRAETHYL LEAD (LEAD TETRAETHYL, TEL) Pb (C2H5)4 From Ethyl Chloride and Lead-Sodium Alloy Crushed led- | Cond<ntr |--^ By-product gam - Ethyl chloride Ethyiene dibromt'de Ethylene dichloride Antiknock fluid containing Tetraethyl lead Reaction 4NaPb + 4C2H5C1 - Pb (C2H5) 4 + 3Pb + 4NaCl 85-90% yield (based on sodium) Material Requirements Basis--1 ton tetraethyl lead (100%) Sodium Lead (theo) Ethyl chloride (theo) Catalyst Ferric chloride Sodium thiosulfate 650lb 1,280lb 1,595 lb 15 to 50 lb Small Small Process Tetraethyl lead is made by reacting a lead-sodium alloy with ethyl chlo ride in n ' octave.

I can say, with complete candor, that there is no better example of this in American industry than the performance of Ethyl Corporation in its safe guarding of the manufacture, distribution and use of tetraethyl lead.

He stated that he had absolutely nothing at all new but that ha had. read over all of the published data on tetraethyl lead as received from the Surgeon General's office and in view of the fact that all lead compounds are poisonous, he felt that the Surgeon General's warning plate was not sufficient.

He stated that he had absolutely nothing at all new but that ha read over all of the published data on tetraethyl lead as received from the Surgeon General's office and in view of the fact that all lead compounds are poisonous, ha fait that the Surgeon General's warning plate was not sufficient.

Lee Sales of Commercially Pure TEL New York New York July 5 1956 In accordance with the request of the Sales Committee, I have reviewed the procedures for sales of commercially pure tetraethyl lead, dilute antiknock compounds and special fluids to non-refinery customers.

- KF 0015831 3oia time ago the question was raised by Thenault ao to the usefulness of Javel water In the decomposition of tetraethyl lead* Calingaert has investigated this subject and has sent rue a report on it, a copy of which 1 enclose for your Information.

Lee Sales of Commercially Pure TEL New York New York July 5 1956 In accordance with the request of the Sales Committee, I have reviewed the procedures for sales of commercially pure tetraethyl lead, dilute antiknock compounds and special fluids to non-refinery customers.

Key words: lead; gasoline; tetraethyl; public health; history; Alice Hamilton; Charles F.

cc. of tetraethyl lead par / alien, satiisfiictory operation v;Tfch a o;inlsum of cleansing was obtained for 111*.76 hours with a single filter unit.

Elements of Industrial Toxicology tivity were observed Gasoline vanes in composition, but is commonly a petroleum fraction containing hexanes, heptanes, and octanes with varying amounts of unsaturated, cyclic, and aromatic compounds A cracked gasoline may con tain 50 per cent or more compounds other than the saturated aliphatic hvdrocarhons If the gasoline consists of saturated and unsaturated aliphatic compounds and cyclic compounds it will be a narcotic and an ir ritant to the mucous membranes The main toxic action will be depression of the central nervous svstem with symptoms of giddiness, dizziness, hilarity, and headache not unlike an alcoholic intoxication Mild symptoms of this sort are apt to be produced by relatively short exposures to concentrations of 500 to 750 ppm of this kind of gasoline In addi tion, mild blood changes, neuritis, and neu rasthenias have been reported If the gasoline is made from a crude oil containing 40 per cent or more of aromatics or is enriched in aromatics by the refining process, the toxicity mav be substantially higher The tetraethyl lead content of gasoline is low enough to make any lead exposures from ordinary handling and dispensing of gasoline in garages and filling stations negligible Tetraethyl lead can however present a toxic hazard by inhalation and absorption through the skin when entry is made into tanks and other confined spaces that have contained leaded gasoline See Lead and Hygienic Guide Germanium, one of the less common metals which have some industrial uses, is employed particularly in the electronics industry for diodes and transistors It appears to be a relatively inert metal and has not been re ported as the cause of any occupational dis eases in man In animal experiments, the LD50 for rats bv intraperitonea!