AR226-3339 Roy S Thompson Ilaria Colombo Watze de W olf (AstraZeneca, Brsxham, UK) (Solvay Solexis, Bolteie, Italy) (DuPont, Mechelen, Belgians) David G Farrar Robert A Hoke Jacques L'Haridon for:(ineos Chlor, Runcorn, UK) (DaPant, Newark, DE, USA) (CIT, Evreux, France) APME (Association ofPlastics Manmcterera in Earops) d-Hoc APFO Eavimaffisatsl Woridag Group _____________ _____ A p ME / Acute & Cfer@icCAoqunatetinctToxicity of APFO Background Physico-chemical properties of APFO Acute toxicity Chronic toxicity Risk assessment Potential role of ammonium ion in APFO toxicity Conclusions Acknowledgements AJpME 1 ArairAtucfutitielii&iitiCphtrrollniiic Arquacttic Tsio#xaitcit-yBoaf AckPgFrOtjiiiid Most commonly used salt o f perfluorooctanoic acid (PFOA) Essential processing aid in fluoropolymer and fluoroelastomer production (e.g.

AR226-3376 HASKELL LABORATORY Common Name: Ammonium Perfhiorooctanoate (C-8) Chemical Name: Octanoic add, pentadecafluoro-, ammonium salt CAS Registry No.: 3825-26-1 Chemical Structure: Physical Properties: OI cc f 3 - c f 2- c f2- c f2- c f2- c f2- c f 2 - - o -+n h 4 Form: Molecular W dght: Boiling Point: Melting Point: Density: White powder 431 Sublimes @ 110C -- -- Drinking Water Guideline (CEGW) 1 ug/L General Toxicity Ammonium perfluorooctanoate (C-8) has moderate acute oral toxicity with an LD50 in rats of 470 mg/kg 981b).

m PATTON BOGGS, ATTORNEYS *T U W VIr**.M.'

AR226-3647 3M ENVIRONMENTAL LABORATORY REPORT NO.

226-3648 INTERIM REPORT #1 Analysis o f Oakdale W ater Samples STUDY TITLE Analysis o f Perfluorooctanoic Acid (PFOA), Perfluorobutanesulfonate (PFBS), Perfluorohexanesulfonate (PFHS), and Perfluorooctanesulfonate (PFS) in Water, Soil, Sediment, Fish, and Clams Using LC/MS/MS for the 3M Cottage Grove Monitoring Program DATA REQUIREMENTS EPA TSCA Good Laboratory Practice Standards 40 CFR 792 STUDY DIRECTOR Jaisimha Kesari P.E., DEE Weston Solutions, Inc. 1400 Weston Way West Chester, PA 19380 Phone: 610-701-3761 INTERIM REPORT COMPLETION DATE May 19, 2005 PERFORMING LABORATORY Exygen Research 3058 Research Drive State College, PA 16801 , Phone:814-272-1039 STUDY SPONSOR 3M Company 3M Building 0236-1-B-10 St.

T-7485: A REPRODUCTION STUDY WITH THE NORTHERN BOBWHITE FINAL REPORT WILDLIFE INTERNATIONAL, LTD.

Katherine E.

^ZZC-3770 ACUTE TOXICITY TO FROG TADPOLES (Spring Peeper) TEST SUBSTANCE_______________________________ f!

P-1 y& TRADE SECRET 2 3 7DuPont-18318 tfa - A/S ?

CXR Biosciences Ltd.

'p QC Laboratories' Analytical Report PETER TYRRELL UNITED HATER CITY OF ORANGE CHESTNUT STREET PLANT AT 632 BEACH STREET ORANGE, NJ 07050 Account No: C00927, UNITED HATER CITY OF ORANGE Project No: C009Z7, UNITED HATER CITY OF ORANGE Sample Nunber L2604751-1 Sample Description CHESTNUT ST Received Temp: 36 F Iced (Y/N): Y Parameter PFOA Method Sample Number L2604751-2 Sample Description ORANGE PARK Received Temp: 36 F Iced (Y/N): Y Parameter PFOA Method Sample Number Sample Description L2604751-3 GIST PLACE Regarding: PETER TYRRELL UNITED HATER CITY OF ORANGE CHESTNUT STREET PLANT AT 632 BEACH STREET ORANGE, NJ 07050 P.O.

P-1 January 15, 2009 DuPont Haskell Global Centers for Health and Environmental Sciences 1090 Elkton Road, P.O.

SEVERN TRENT STL STL Chicago 2417 Bond Street UniversityPark, IL60466 Tel: 708 534 52G0 Fax; 70S 534 5211 www.sW-;'nc.M/n VERN TRENT LABORATORIES ANALYTICAL REPORT J O B T O M B E R : 2.45833 P r e p a r e d F o r : ,..

STL Burlington Colchester, Vermont Extended Data Package SDG: 117507 Case Narrative Chain of Custody................................................................................................

M &Z6 - 0 7 2 9 ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE_________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-206 or L3243. (1-Octanesulfonic acid) (CAS # 2795-39-3).