.: Sponsor: None 30% None available DuPont Specialty Chemicals E.

CONFIDENTIAL AR226-1307-4 DuPont Epidemiology Surveillance Report MORTALITY AND CANCER INCIDENCE SURVEILLANCE AT WASHINGTON WORKS Requester: GeralAd.

AR226-3342 Environmental fate studies o f fluorotelomer interm ediates used to produce surfactants and p o ifin e rs Bill Berti DuPont Central Research & Development Wilmington, Delaware USA Themiracles o f science Acknowledgements uNing Wang Daryl Cobranchi ^Barbara Larsen Bogden Szostek Mary Kaiser John Gannon Bob Buck Lisa Sulecki Pat Folsom Mark Starr Chien-Ping Kao Christopher Bowers Vladimir Capka (ffypoft Outline Background Intermediates and Products Overview of E-fate studies Physical-Chemical Properties Water solubility and Vapor Pressure . 6-2TBI, 8-2TBI, 6-2TBA, 8-2TBA Measured vs.

ACKNOWLEDGMENTS The authors thank Kim Kreckmann and Craig Marshall of the Epidemiology Program at DuPont Haskell Laboratory for Health and Environmental Sciences, Martin Slade MPH of the Yale Occupational and Environmental Medicine Program, and Ellen Eisen ScD o f the Harvard School of Public Health.

WW 3561492 collected:02/28/2001 10;4S by BCJD submitted: 03/01/2001 09:25 Reported: 03/28/01 at 12:52 PM Discard: 4/28/01 WWK-S-LPWD_WELL_.A, Unsplked Water Sample LUBEO-t WELDS 1Q01 Page 1 o f1 .. account Bvmber: 07032 CR-B.1.DuPont de Nemours & Co Barley Mill Plaza, Bldg. 27 Lancaster Pike & Route 141 Wilmington DE 19805 Q0&XX SDS#l XXXOl-OIBKC Car Ko. 02324 00495 As Received Analysis iam.i As Received CAS limber Result FC-143 3B2S-26-1 0.648 Tfce spike recovery few the WS/MSD is outside the QC limits.

Through thfe assessment and investigation, Dupont ha fdeBttBed a new analytical roathod that should (wvxte greater precision and accuracy for data that te genemed.

In the 1960s, DuPont developed a perfluorosulfonic acid (PFSA) membrane, or the Nafion series of products.

Szostek B.2, Buck R.C.3, Folsom P.W. 1, Sulecki L.1, Powley C.2, Berti W .1, and Gannon J.T.1 1DuPont Central Research and Development, Newark, USA; 2 DuPont Haskell Laboratory; USA ; 3 DuPont Chemical Solutions Enterprise, USA.

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.: Sponsor: Study Initiated - Completed: In Life Phase Initiated - Completed: DuPont Specialty Chemicals E.

Unpublished measuamenfa, FkiowetEASOO DuPont, 8 E T A C 2003, Ham bug Sweeter, P A , Decomposition of Organic Fluorine Compound byWWdrokl Oxytiydrogen H Analytics!

FLAIR DOCUMENTS AR226-3477 AR226-3477 FLAIR Work and Medical Historiesfo r A ll Employees A nd A ll Years Tuesday, November 09, 2004 Page 1 o f 897 0600 0340-S Date o fSample C8 Concentration UTILITY POOL FILAMENTS SERF OPER 8/8/1984 3/1/1985 3/15/1988 9/26/2002 9/27/2002 0.05 0.05 0.2 0 0 157 362 1472 6780 6781 12/3/1979 5/16/1980 5/16/1980 3/4/1984 3/4/1984 Tuesday, November 09, 2004 JBidacied *Prlraity Page 2 o f 897 0600 UTILITY POOL 0340-S FILAMENTS SERF OPER 0442-S POWER SERF OPER 1540-S C&P COLOR AND SERF OPER 1560-S C&P COLOR AND PROC OPER 0500 MECHANIC 3/15/1994 0.46 3/6/1963 5/6/1963 5/6/1963 1/2/1967 1/2/1961 2/12/1968 2/12/1968 10/21/1968 10/21/1968 1/31/1912 1/31/1912 Tuesday, November 09, 2004 Page 3 o f 897 Date o fSample C8 Concentration 0600 UTILITY POOL 0340-S FILAMENTS SERF OPER 0940-S BUTACITE SERF OPER 0600 UTILITYPOOL 0340-S FILAMENTS SER F OPER 0940-S BUTACITE SERF OPER 0700 LABORA TORIAN 0002-W MILITR Y SER FICE WAGEROLL 0700 LABORAT0R1AN 0760-S TECH LAB SR LABN 0500 MECHANIC 0500 TF MECHANIC TEFLON 2/22/1982 0.83 2482 6/28/1963 7/2/1963 7/2/1963 9/26/1963 9/26/1963 10/18/1963 10/18/1963 1/17/1964 1/17/1964 2/27/1964 2/27/1964 3/25/1964 3/25/1964 8/20/1965 8/20/1965 1/17/1966 1/17/1966 12/19/1961 12/19/1968 1/25/1972 1/25/1972 5/8/1975 5/8/1975 Tuesday, November 09, 2004 Redacted - Fjv Page 4 o f 897 Begin Date End Date_ 0600 UTILITY POOL 6/17/1959 7/20/1959 0251-H ZYTEL CASTER BLENDER (DAYS) 7/20/1959 4/11/1960 0600 UTILITY POOL 4/11/1960 5/16/1960 0340-S FILAMENTS SERV OPER 5/16/1960 11/18/1960 0001-W NO WORK (LAY OFF) WAGEROLL 11/18/1960 11/13/1961 0600 UTILITY POOL 11/13/1961 12/4/1961 0340-S FILAMENTS SERV OPER 12/4/1961 5/14/1962 0340-S FILAMENTS SERV OPER 5/14/1962 7/7/1963 0340-S FILAMENTS SERV OPER 7/7/1963 3/6/1966 0250-H ZYTEL BLENDER 3/6/1966 5/1/1966 0245-H ZYTEL MATERIALS HANDLER AND SUPPLY CLERK 5/1/1966 2/26/1967 0250-H ZYTEL BLENDER 2/26/1967 4/2/1967 0240-S ZYTEL POLY SERV OPER 4/2/1967 7/2/1967 0250-S ZYTEL CASTER BLENDER 7/2/1967 12/24/1967 0240-S ZYTEL POLY SER V OPER 12/24/1967 1/5/1969 0442-S POWER SERV OPER 1/5/1969 8/29/1971 0457-H POWER DRIVER 8/29/1971 5/10/1974 1441-H MECHANICAL SER V OPER 5/10/1974 1/13/1975 Tuesday, November 09, 2004 P ftife-vv01 Page 5 o f 897 0500 MECHANIC 0500 TF MECHANIC TEFLON 1/21/1982 0.19 1/13/1975 4/30/1978 4/30/1978 1362 Tuesday, November 09, 2004 Redacted - Pr'vac; Page 6 of 897 Job Code Job Title Begin Date End Date Date o fSample C8 Concentration Days in Teflon at Time o f Sample 060 UTILITYPOOL V TM 1977 6/29/1977 0340-S FILAMENTS SERV OPER 6/29/1977 10/1/1977 0840-S FP TEFLON TFE SERV OPER FINE POWDER 10/1/1977 10/2/1977 0840-S TEFLON TFE SERV OPERJFINE PWDR-DISP SERV O 10/2/1977 6/1/1978 0844-S 0844-S 0866-S TEFLON COPOLYMERS FEP SERV OPER 6/1/1978 6/12/1978 TEFLON COPOLYMERS FEP SERV OPER 6/12/1978 9/25/1979 1-7 724 TEFLON COPOLY TEFZEL-TEL A OPER/DISP FIN O 1/2/1980 7/15/1981 0.98 1383 7/12/1982 0.77 1745 1/2/1980 Tuesday, November 09, 2004 n.

This research is funded by the C8 Class Action Settlement Agreement (Circuit Court of Wood County, WV, USA) between DuPont and plaintiffs, which resulted from releases into drinking water of the chemical perfluorooctanoic acid (PFOA, or C8) .

USA) between DuPont and plaintiffs, which resulted from releases into drinking water of the chemical pcrfluorooctanoic acid (PFOA, or C8) Funds were administered by the Garden City Group (Melville, NY) that reports to the court.

I. du Pont de Nemours and Company (DuPont) hired me to carry out the analyses.