v ; your letted addressed to the Ethyl Gasoline Corporation has been referred to ste for reply* The Inhalation of load-containing gaSoltnee-- has not been associated with the occurrence of lead poisoning among gasoline handlers* In fact there.have been no oases of poisoning reported anywhere 'as a consequcneo of. exposure to-leaded-.gasoline, either by'-inhalation or as' a result of. akin, contact* I. and, my associates In this laboratory have studied this problem over a period of years, and 1 am sending you a reprint of an article which recently. appeared in..

/ for the prevention of lead poisoning in children.

These will also add to growing public awareness and concern over childhood poisoning from lead-based paint, soils, drinking water and plumbing fixtures.

This is a bul letin entitled "Occ upational Lead Exposure an a Lead Poisoning" and i 3 a report prepared by the Committee on Lead oisoning of the Industrial Hygiene 3 C L1 on cf the American Public .on of vhiich I had the honor to be chairman.

Shropshire of the International Lead Refinery in East Chicago, Indiana, I have taken the liberty to write you in an endeavor to get some information on the possibility of lead poisoning occurring from swallowing or breathing the dusts occurring in this operation.

Xhe type of illness .sad its;course were not such as to Justify a diagnosis of lead poisoning.

Meanwhile, however, a considerable proportion of the lead is lost from the body by various routes, and it is not easy, therefore, to produce the picture of chronic lead poisoning.

On the other hand, I have no doubt that if industrial workmen vere exposed to lead silicate distributed into the atmosphere in sufficiently finely divided state and in sufficient dosage, cases of lead poisoning would develop among them.

Manfred Bowditch, Director of Health and Safety of the Lead Industries Association, has agreed to hold a registry of such protocols of Ca EDTA treated cases of lead poisoning in his office at U20 Lexington Avenue, New York 17, N.

The existing Lead-Boted Point Poisoning Prevention Act colls for a 1% level, while the regulations issued by FDA, in effect, reduce this to .5% effective January 1,1973.

Perhaps you are in some doubt as to why X .offer to do this without having precise Infor aafcion as to the nature of the an*a illness* My answer to this Is that I am wholly convinced both from experi mental evidence and from m y clinical experience of the past fifteen years in this field, that exposure to lead in the handling of leaded gasoline is of such an entirely negligible proportion that It is quite Impossible, in m y opinion, for lead poisoning to occur as a consequence of such exposure* So far as I have been able to discover, both from experimental and clinical evidence, no cases of lead poisoning have ever occurred from this cause, nor are any cases likely to occur* Consequently, in m y opinion, if the Mayo Clinic group of physicians, or any other group, mad a diagnosis of lead poisoning on the assumption that lead was absorbed in the case of the filling station . 0810393 -- i*. -- 2 ; operator's occupation, they wre almost certainly In error In their assumption and they Here probably entirely wrong in their conclusions, although I consider it very improbable that any such diagnosis was made.

Boone Materials Technologist Lead Paint Poisoning Project Enclosure cc: H.

In so far as ar. 4Ml is concerned, you can assure Kr* 't;e.rherson that there- is no likelihood of Shaw acquiring lead poisoning from the hetidll&g of loaded gasoline. $* have eecn no e&aee of-lead poisoning which were over contracted or contributed to by work with leaded gasoline; and moreover, all of th evidence which we and others have accumulated leads us. to the opinion that there is no likelihood of poisoning from this source from the handling cf leaded gasoline as ordinarily carried out in eoeu&erce.

peaaies* M i other faster concerns the possible health hazard which the growing m e of lead impre<piated gasoline presents Lead poisoning is as you know, on of the most dangerotas forms of toxioatios Isiowa.

i I signs of poisoning remains a difficult problem.