X July 31, 1973 Microscopic Detection of Asbestos in Talc by Arnold E.

r.

DIRECTOR OK THE INTERNATIONAL AGENCY FOR c-orco c o o o o e o ON CANCER The meeting was held at Die International Agency for Research on 1 Lyon, France on Rtb and 6th October, 1972* The Committee consisted of panels - Epidemiology, Pathology, Physics and Chemistry Epidemiology Panel Dr M.

QRAC - 3- 3I Method 1: based upon fitting bt c (nonincidental analysis) to a 1922-1946 cohort of the Selikcff, et. &1. data.

DEPARTM ENT OF HEALTH, EDUCATION, AND W ELFARE PUDLIC HEALTH SERVICE FOOD AND DRUG ADMINISTRATION W A S H I N G T O N .

K-"Mo?

FILE NAME: Talc (TALC) DATE: 1973 June 29 DOC#: TALC078 DOCUMENT DESCRIPTION: Newspaper Article - FDA Asked to Ban Asbestos Filters n/ t" 'll 73 F.D.A.

FILE NAME: Talc (TALC) DATE: 0000 DOC#: TALC059 DOCUMENT DESCRIPTION: Unpublished Report - FDA & Talc Cosmetic Use of Talc It has long been known that talc minerals are commonly contaminated with asbestos.

Si MedicBarlitJisohurnal ial experiments ,tudy do not give pens m the lungs The study whirl; t answer to the e to measuie the uct of histamine jrine from cardisible in the near ect evidence, and tioned that in a workers an anti chloride, 5 mg the decrease of irking day of the extracts contain ydroxytryptamine demonstrated." : ic" shows that the e far too small to jronchi in vivo.' ect of dust extract histamine.1 Ltke; is very weak, as .es no contraction vo11 even though e the presence of je of interest to at it need not dis byssinosis. the only theory peculiar symptom arkers.1 A non its may also be 1 asthma, and this n of cotton dust is leoretical interest, ionai hygiene the ot the active agent tvs of the workers, from the dust the ' the lungs in intact tt stomach or the >n may be useful n effects of textile etc., A.

sb THE PATHOLOGICAL EFFECTS OF SUBCUTANEOUS INJECTIONS OF ASBESTOS FIBRES IN MICE: MIGRATION OF FIBRES TO SUBMESOTHELI^L TISSUES AND INDUCTION OF MESOTHELIOMATA by K J.

* American Paper Instituteserving the pulp, paper andpaperboard industry 260Madison Avenue, New York, N.Y. 10016 / (212) 889-6200 cable address: AMPAPINST NewYork December 21, 1973 Hearing Clerk Food and Drug Administration Room 6-86 5600 Fishers Lane Rockville, Md. 20852 SUBJECT: Notice of Proposed Rulemaking published September 28, 1973, 38 Federal Register, 27076--27081 (1972) _______ Comments of American Paper Institute, Inc.__________ Dear Sirs: The American Paper Institute, Inc.

j ANALYST WORK SHEET 3.

2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 TABLE II INTERLABORATORY COMPARISON OF ANALYTICAL RESULTS FOR TREMOLITE IN COSMETIC TALCUM-TYPE POWDERS ___________________________________ RESULTS_________________________ _________ N.

MEMORANDUM OF VISIT September 28, 1976 / // ff-yO BETWEEN: Ms.

OLUMBIA FILTER COMPANY J C .P.O.