Kehoe, the drawn:- 1) There is no reason to fear the existen health from the distribution and use of leaded ga 2) Experimental evidence has indicated th absorption fuom skin contact and inhalation of va tetraethyl lead were practically negligible; 3) The lead exposure associated with the gasoline containing tetraethyl lead at service st 4) The lead exposure arising from prolong and repair of automobiles using leaded gasoline f to cause slight increase in the mean rate of arin either in a greater lead output per unit time or No increase in the fecal lead excretion has been 5) There is no reason to believe that the service and repair work involves danger from lead 6) Because of the number and variety of o exposure to lead in the garage mechanic's occupat lead exposure deriving from leaded gasoline and i conjectural.

The saturated yapor of tetraethyl lead in air atordinary temperatures contains approximately 5 age. of lead per liter' of air - a concentration Which la lethal for experimental animals after a few hours of exposure.

The specific occasion for this letter arises from the correspondence vhieh I have received recently in connection vith tvo cases of tetraethyl lead poisoning treated by Dr.

The saturated vapor of tetraethyl lead in air at ordinary temperatures contains approximately 5 age. of lead per liter' of air - a concentration Which is lethal for experimental animals after a few hours of exposure.

Stecher, Manager Tetraethyl Lead Division .

For example, derma titis is practically unknown in the plants where tetraethyl lead is manufactured.

It would ppear that when leaded gasoline that contain* 3 co of lead Sc used stsasurable ajaou&ts of lead are found is the flue $*#*,- but that the greater proportion of this o&m& over in the first 30 ntlnutea while the stove Is coming to temperature, ad w have further found that the lead which, passes the filter In the early minute* of running is in the form of tetraethyl lead, `fills of course does not escape into the flue g&* as it is completely decomposed in passage through the flame, but it does suggest the possibility that improvements in the .stove could be mads that would enable more complete decomposition of the tetraethyl lead while the stove is being started.

3 on of lead i s used aoiiurablo mounts of lead are found in the flue $9*9,- but that the treater proportion of this ao t .e s over in the first 30 minutes while the stove is cosing to temperature, m & we have further found that the lead which, passes the filter In the early minutes of running i s i n the f o rm of tetraethyl lead.

Dr, Machle calls my attention to the fact that you did not have copies of two reprints of ours which we felt you should have in your office for the information of persons who might request them* Therefore I am sending you under separate cover two copies of "An Appraisal of the Lead Hazards Associated with the Distribution and Use of Gasoline Containing Tetraethyl Lead, Part I", and half a dozen copies of our study on "The Occupational Lead Exposure of Men Engaged in Mixing Tetraethyl Lead with Gasoline", Very truly yours.

Variations in the concentration of lead in the blood of humans exposed to and removed from industrial exposure to tetraethyl lead. 5.

Please advise me if it is possible to obtain this amount of tetraethyl lead.

in gasoline, the Service's opinions were sought by industry, because both Tetramethyl lead and Tetraethyl lead are known to be potentially toxic (substances).

This is not true of tetraethyl lead vapor in the absence of other organic vapors.

acute illness was the result of absorption of tetraethyl lead and certain of its decomposition products.

Wo such changes occur even in fatal tetraethyl lead intoxication.