Bladder Cancer in Perfluorooctanesulfonyl Fluoride Manufacturing Workers Final Report Bruce H.

JOSEPH E.

FILE NAME: Asbestos in Plastics (AIP) DATE: 2005 Oct DOC#: AIP009 DOCUMENT DESCRIPTION: Journal Article - Occupational Exposure to Airborne Asbestos from Phenolic Molding Material - Bakelite - During Sanding, Drilling, and Related Activities Journal o f Occupational and Environmental Hygiene, 2: 497-507 ISSN; 1545-9624 print / 1S45-9632 online Copyright 2005 JOEH, LLC DOl: 10.1080/15459620500274237 Occupational Exposure to Airborne Asbestos from Phenolic Molding Material (Bakelite) During Sanding, Drilling, and Related Activities Fionna Mowat,1 Michael Bono,2 R.J.

i ACADEMIC PRESS Available online at www.sciencedirect.com SCIENCE ECT Regulatory Toxicology and Pharmacology 38 (2003) 58-70 Regulatory Toxicology and Pharmacology www.elsevier.com/locate/yrtph Airborne asbestos concentration from brake changing does not exceed permissible exposure limit Charles L.

The north wall of this garage angled into a hallway that lead to offices and the main shops located to the north Barriers and isolation devices were not utilized to seal the test area from this section of the service facility due to its distance from the actual test area and to aid in maintaining standard environmental conditions Area samples were collected from midway between the two shop areas which showed an absence of airborne fiber migration from shop A warehouse used for storage purposes was located adjacent to the north wall of the garage Existing materials and equipment were left inside the automotive service facility and the connecting hallway during the testing This included but is not limited to parts bins used tires compressed gas bottles trash receptacles a tire inflation safety cage and two fully functional hydraulically operated automobile lifts Vehicles receiving service entered from the west side and exited from the east side or vice versa The ventilation system located within the two automotive service garage was shut down during the three days of testing Testing was performed in an unventilated facility to facilitate a worse case scenario Also the rollup vehicle doors remained closed during each test session The four rollup doors were opened between test sessions to remove airborne particles generated during the previous test sessions 2.2 Test vehicles Vintage vehicles utilized in this experiment were selected based on 1 the likelihood of encountering containing gaskets and 2 the availability of new replacement containing engine gaskets The tested vehicles included a 1974 Chevrolet Malibu 1978 Chevrolet pickup truck and a Ford 390 cubic inch V engine Table 1 contains a brief description of the vehicles and engines utilized in this study 2.3 Mechanic's activities equipment and tasks The professional automotive mechanic was Automobile Service Excellence ASE certified and was instructed to perform gasket removals or installations using his standard operating procedures SOP Thus he was allowed to select all tools and equipment to ensure limited interference with his job practices Tools utilized during this experiment included wrenches screwdrivers scrapers and hammers in addition to pneumatic powered ratchets for the removal of bolts and nuts The mechanic was directed to wear a normal work uniform to further ensure realism and avoid use of cumbersome or uncomfortable garments which would have interfered with his normal activities or work habitats Five individual test sessions were conducted to assess the levels of air- borne asbestos fiber generated during the servicing and handling of asbescontaining gaskets Three test sessions focused on the partial disassembly of engines and the removal of gasket remnants from engine receiving surfaces and loose parts The two remaining test session

Folate levels along with genetic regulation of folate metabolism have been the focus of many investigations 8-19, predicated on the notion that they may influence the creation and/or expansion of the pre-leukaemic clone via DNA hypomethylation of key regulatory genes as well as uracil misincorporation into DNA leading to double strand breaks and chromosomal aberrations 20;21.

ACADEMIC PRESS Available online at www^eiencedirectcom SCIENCE ^DIREOT* Regulatory Toxicology and Pharmacology 38 (2003) 58-70 Regulatory Toxicology and Pharmacology www.dscwsr.com/loeate?

3 The Plastics Industry Trade' Association AA<_f i - f i . 15OH- Donald K.

The mechanisms and pathways leading to the presence of PFOS in human blood arc not well characterized but likely involve environmental exposure to PFOS or its precursor molecules and residual levels of PFOS or PFOS precursors in industrial and commercial 3M Cotton:, /- products.

These species are analogous to HFCs with the addition of an ether linkage, reducing the atmospheric lifetimes, leading to lower GWP for these compounds compared to those of HFCs.

FILE NAME: Asbestos in Plastics (AIP) DATE: 2005 Oct DOC#: AIP009 DOCUMENT DESCRIPTION: Journal Article - Occupational Exposure to Airborne Asbestos from Phenolic Molding Material - Bakelite - During Sanding, Drilling, and Related Activities Journal o f Occupational and Environmental Hygiene, 2: 497-507 ISSN; 1545-9624 print / 1S45-9632 online Copyright 2005 JOEH, LLC DOl: 10.1080/15459620500274237 Occupational Exposure to Airborne Asbestos from Phenolic Molding Material (Bakelite) During Sanding, Drilling, and Related Activities Fionna Mowat,1 Michael Bono,2 R.J.

AMERICAN JOURNAL OF INDUSTRIAL MEDICINE 45:229-237 (2004) Asbestos in Brakes: Exposure and Risk of Disease Richard A.

P-1 PFOS: A 96-HOUR STATIC-RENEWAL ACUTE TOXICITY TEST WITH Hyalella azteca FINAL REPORT WILDLIFE INTERNATIONAL, LTD.

52 Late lessons from early warnings: the precautionary principle 1896-2000 5.

FILE NAME: RT Vanderbilt (RTV) DATE: 2004 DOC#: RTV004 DOCUMENT DESCRIPTION: Journal Article - Reconstruction of a Century of Airborne Asbestos Concentrations Environ.