ARR EG -- 1828 Final Report on A Pharmacokinetic Study of Potassium Perfluorooctanoate in the Cynomolgus Monkey ~~T-757:!

ARQR6 -- 136] A Pharmacokinetic Study of Potassium Perfluorohexanesulfonate in the Cynomolgus Monkey Southern Research Institute Study ID: 9921.5 April 22, 2003 001599 Final Report on A Pharmacokinetic Study of Potassium Perfluorohexanesulfonate in the Cynomolgus Monkey To: 3M Corporation P.O.

AR226 _ 0636 Barbara Loczynekd os052000 0307 To: Karen LannoniDCAUSEPAIUSGEPA, Mary DominaiiDCIUSEPEAPUAS o Sublet tolown oporurochenmicals meting on Api 28 %gson re Forwarded by Barbara LecaynskIDGIUSEPAIUS on 05052000 03:31 PM VBS womenC1 Cranes aver 2 s oEXF GB083000 1203 PM >2 To dbPocobhrsalukuseDusGmtIa@UnmS@mEumPcoAooSmmG.EOPsAc.arBHoeamrasnLdoecuoDGyUmSsEkPIADUUSS@EESPAAS,BNEoPlAPallDUSEPAUS@EPA, Robert Sublet folows 1 peruarochemcals meeing on A 25 Dear Bil and Dan, 3M, Wanedfootuhnrd ptheerfmoereotcihngemviecraysh. eSteveirnaflurptihenrsingcaoumreuunpdeirnstthaendmienegtionfgtdhissciutsuastiioonnawnitdh|rweogualrdd tiokePFoOrSeay our thinking n mai form.

(f wontons 7s cansormpenseAssas emo.kea.com ubiect cx Seotengard a 0825100 09:07 AM Safest Seok ivkommient KEATBFRIOAT681808 0008 B07 Dear Mrs Brower, Refering to the EPA press release of May.16.2000 concerning 3M and their Scotchgard-product;based-on the"ehemicat PROSTM etftohresetnhadtotfhtehEePpArewsassreplleaansnei,ntghetorecoisntaacmtenftorieoingnofgtohveerrV"omleunnttsaaryndphoathseerocuhteomficPaFlOmSanaunfdacrieulraetreds cthoegmeitcaslusp.port foar iAstauhpormoedufcutrsniwsihtihngstcaoinm-praenpye,llwntevheaavtemesnotmeofutphheoclosvteerred furefaabrticesd, wOifthcohuers3e,Wwberaanrde, nboowtpfhoarstehienNgoorutthtAhmaesreiwchaincmhawrekreet and for other sales countries (30 in ota), SBSiuWm.tilwIaner piwanorfuiolcrdumlabatreioavnnefrayrlotimenrtonetarhteiesvrteecdpormifoptdahunecitEewPsiAahshwayhsoiucmharenscaoegmiveeeddofffoorugoremt prodice are treated is the Dupont Teflon-oased finish hIneyaolutrecffpecitos,ofdtoiysocuhceomnisciadlecratnatreahsesonnaytlryobnemeexpretcstaendldto De of a similar nature as the PFOS?

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Sponsor: APME Ad-Hoc APFO Toxicology Working Group FINAL REPORT Study Title: 4-Week Capsule Toxicity Study with Ammonium Perfluorooctanoate (APFO) in Cynomolgus Monkeys Author: Peter J.

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Toxicological Summary PFOS Dietary Chronic Definitive Reproductive Study: Northern Bobwhite Test Substance: Perfluorooctanesulfonate (PFOS) Structure: 1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro, potassium salt.

A-- AR236- (544 STUDYTITLE Extactonof Psassum Perflcrocuncslfose fom gg Membrane, Albumen, and `Yolk for Analysis Using HPLC-Electrospray/Mass Spectrometry DATAREQUIREMENTS Analytical Method Requirements STUDYDIRECTOR - Sean Gallagher STUDYCOMPLETEDON Sepimber 06,2001 = PERFORMINGLABORATORY/ TESTINGFACILITY Conte Ans0o48nRLebsoearrscrhireis,veIn.

AR226-2555 Robert F Pinchot 05/11/2000 07:31 AM To: co: Subject: David M Rurak/AE/DuPont@DuPont, Michael E McCord/ABDuPontQOuPont, Robert J Cavanaugn/DuPontQDuPont, Luk D'Haenens/EUR/DuPontOuPont, Roger J 21pfel/AE/DuPont@DuPont, Anthony J playtis/CL/DuPontDuPont, Arie sl Vermeulen/EUR/DuPont@DuPont, Gerald L Kennedy/AE/DuPont<aDuPont, William R Berti/AE/DuPont@DuPont, John Gannon/AE/DuPontQDuPont, Robert L Rltchey/CUOuPont@OuPort, Andrew 8 HarttBn/A6/DuPont@DuPont, Susan S Mileti/DuPont@DuPont Andrea V Malinowski/A/DuPont@DuPont, Maurice Astorga/AE/DuPont@DuPont, Richard J Angiullo/AE/DuPontQDuPont, Bernard J Reilly/AE/DuPontQOuPont, Gary W Jepson/AE/DuPont@DuPont PFOA EPA Request As many of you know, the Office of Pollution Prevention and Toxics in the US EPA has requested that DuPont supply a large amount of information on Pertluorooctanoate (PFOA or C-8).

Larry R.

T3eMaCrosrporyosrautevToSxerivics ology and 8S1t7aC5l3e, e17B7eFlaxin40200603 SEHR 120500373 ARARG_ 3872 RECEIVED Certified Mail OSDEC-8 AM 6:05 November 29, 2005 Document Processing Center EPA East - Room 6428 Attn: Section 8(e) Officeof Pollution Prevention and Toxics USEPA 1200 Pennsylvania Avenue NW.

p. 1 TAFT, STETTINIUS & HOLLISTER LL P NORTHERN KENTUCKY OFFICE CLEVELAND, OHIO OFFICE SUITE 340 3500 BP TOWE R 1717 DIXIE HIGHWAY COVINGTON, KENTUCKY 41011-4704 425 WALNUT STREET, SUITE 1800 200 PUBLIC SQUARE CLEVELAND, OHIO 44114-2302 606-331-2838 216-241-283 8 513-381-2838 FAX : 513-381-6613 CINCINNATI, OHIO 45202-3957 FAX : 216-241-3707 COLUMBUS, OHIO OFFICE DAYTON, OHIO OFFICE SUITE 900 110 NORTH 513-381-2838 21 EAST STATE STREET : 513-381-0205 COLUMBUS, OHIO 43215-4221 MAIN FS AX TREET 614-221-2838 DAYTON, OHIO 45402-1786 FAX :614-221-2007 937-228-2838 www.taftlaw .co m FAX: 937-228-2816 1-9 c2 a 6 3 ROBERT A . (513) 357-963 8 bilott@taftlaw.com BILOTT !!

European Society for Gynaecological Endoscopy European Chemical Agency (ECHA) To whom it may concern Submission of Evidence of the European Society for Gynaecological Endoscopy regarding the proposed PFAS restriction.