AMERICAN JOURNAL OF INDUSTRIAL MEDICINE 29~225-226( 1 996) EDITORIAL Benzene and Blood: One Hundred Years of Evidence Philip J.

-..I L ' CS) I L d 1, 183-188 March/Aprr/ 1992 INcE9P.!

ICANCER RESEARCH 58. 2I76-2ISI.

222 MALIGNANT PERITONEAL MESOTHELIOMA MALIGNANT I i 1 I * i MALIGNANT PERITONEAL MESOTHELIOMA Case report and review of the literature G.

REGULATORY TOXICOLOGY AND PHARMACOLOGY 21, 307-321 (1995) Cell- Type-Specific Leukemia Analyses in a Combined Cohort of More Than 208, 000 Petroleum Workers in the United States and the United Kingdom , 1937- 1989 OTTO WONG* AND GERHARD K.

Carcinogenesis vol.19 no.9 pp.15651571, 1998 Hemoglobin and albumin adducts of benzene oxide among workers exposed to high levels of benzene Karen Yeowell-O'Connell, Nathaniel Rothman1, Martyn T.Smith2, Richard B.Hayes1, Guilan Li3, Suramya Waidyanatha, Mustafa Dosemeci1, Luoping Zhang2, Songnian Yin3, Nina Titenko-Holland2 and Stephen M.Rappaport4 Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7400, 1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, 2School of Public Health, University of California, Berkeley, CA 94720, USA and 3Chinese Academy of Preventive Medicine, Institute of Occupational Medicine, Beijing, China 4To whom correspondence should be addressed Email: stephen_rappaport@unc.edu Benzene oxide (BO) reacts with cysteinyl residues in hemoglobin (Hb) and albumin (Alb) to form protein adducts (BO-Hb and BO-Alb), which are presumed to be specific biomarkers of exposure to benzene.

FILE NAME Household Contact HC DATE 1996 DOC HC022 DOCUMENT DESCRIPTION Journal Article - Pleural Mesothelioma and Household Asbestos Exposure REVIEWS ON ENVIRONMENTAL HEALTH MED MED 1116 VOLUME 11 NOS 1-2 1996 Pleural Mesothelioma Household Asbestos Exposure Joachim Schneider Kurt Straif and Joachim Woitowitz Institut und Poliklinikf^...rArbeits- und Sozialmedizin der Universit^/tGiessen Aulweg 129 35385 Giessen Deutschland SUMMARY This article discusses the development of induced malignant mesotheliomas after occupational environmental exposure to asbestos through contact with occupationally exposed household members In our policlinic we have seen six fatal pleural mesothelioma cases five wives and one son of asbestosindustry workers with ---- history of occupational asbestos exposure In five women a causal relation was established between the fa disease and inhalation of asbestos fibers whue cleaning the contaminated work and shoes of their husbands at home The son had also been exposed to asbestos throughout his childhood during daily visits with his father at the workplace INTRODUCTION Asbestos mesothelioma No. 4105 of he German Ordinance of Occupational Diseases BeKV is one of the most frequently compensated occupational cancers / Malignant mesothelioma is specifically regarded as a signal tumor of previous exposure to asbestos in the workplace 2 To our knowledge causes other than asbestos and The comparably persistent mineral Erionite have not been found 3,4 Mesothelioma is considered a marker for occupational asbestos exposure as well 5,6 Asbestos mesotheliomas have been described in the vicinity of asbestos mines in South Africa 7,8 Canada 9 Australia 10,11 and C 12 Industrial asbestos manufacture also presents a significant health risk to the environment In Saxony 13 and especially in the HamburgBergedorf area the incidence of mesothelioma Freund Publishing House Ltd. 1996 cases was significantly increased in areas that are close to industrial asbestos emitters 14-17 Many reports have emerged from Turkey 18-20 the northwestern part of Greece 21 and Corsica 22 23 about the endemic incidence of diffuse malignant mesotheliomas caused by environmental exposure to asbestos or Erionite through soil erosion In certain regions of central Anatolia mesothelioma incidence figures of up to 216 per 1,000,000 inhabitants have been recorded although the expected mesothelioma incidence in the general population was very low The estimate of an annual mesothelioma mortality rate of 1 to 8 per one million inhabitants 24-26 relates to about one mesothelioma death per 1000 to 10,000 deaths from all causes An article by Grossgarten and Woitowitz 6 presents an overview of asbestosinduced pleural mesotheliomas that are linked to indoor inhalation by household contacts PATIENTS AND EXPOSURE CRITERIA In our policlinic we have seen asbestos tumors in members of households where at least one worker had been occupationally exposed to asbestos Between 1986 and 1994 five women and one young man one patient's son with no occupational history of asbestos exposure died of - asbestos mesothelioma Their ages ranged from 42 to 68 years Table ) The diagnosis was always confirmed by histology on specimens autopsy Detailed job histories revealed that neither the women nor # the son had ever worked in an asbestos factory Asbestos exposure was exclusively through residential inhalation of asbestos from contaminated work clothes or shoes that were brought home from / the workplace by the husband Throughout his childhood the son had regularly delivered a hot 65 66 J.

FILE NAME Insurance Industry INS DATE 1990 DOC INS072 DOCUMENT DESCRIPTION Book Excerpt - Medical Risks Trends in Mortality by Age & Time Elapsed - Study - Associated Disease Book Sponsored by Insurance Association MEDICAL RISKS Trends in Mortality by Age and Time Elapsed VOLUME 1 _ A Reference Volume Sponsored by The Association of Life Insurance Medical Directors of America and The Society of Actuaries Edward A.

,* MHMI t. l tt(M Mm I t I Mum Hi* /U !

FILE NAME Kaiser Gypsum KG DATE 1998 DOC KG051 DOCUMENT DESCRIPTION Legal - Deposition of John E.

ft INDOOR AIR POLLUTION AND HEALTH "1 Testimony of Jonathan M.

UNITED NATIONS ENVIRONMENT PROGRAMME INTERNATIONAL LABOUR ORGANISATION WORLD HEALTH ORGANIZATION INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY ENVIRONMENTAL HEALTH CRITERIA 203 CHRYSOTILE ASBESTOS This report contains the collective views of an international group of experts and does not necessarily represent the decisions or the stated policy of the United Nations Environment Programme, the International Labour Organisation, or the World Health Organization.

American Journal of Hematology 38:147-149 (1991) Occupational Risk for Hematological Malignancies Paolo Pasqualetti, Raffaele Casale, Domenico Colantonio, and Antonio Collacciani Department of Internal Medicine, School of Medicine and Surgery, Chair of M e d i i 1 Patho@y, Universlty of CAquiia (P.P..R.C..

FILE NAME: RT Vanderbilt (RTV) DATE: 1993 DOC#: RTV055 DOCUMENT DESCRIPTION: Legal - Affidavit of Arthur Rohl N.

FILE NAME: Talc (TALC) DATE: 1995 DOC#: TALC039 DOCUMENT DESCRIPTION: Autopsy Record A D T OPSY NO.