Depo of R.

T. . . . 6 060004 USFW 0580 3.1.2 TAL M etals........................................................................................................ 7 3.1.3 Pesticides/PCBs................................................................................................ 8 3.1.4 VOCs ............................................................................................................... 8 3.1.5 Total Fluoride .................................................................................................. 9 3.1.6 Organofluorides................................................................................................ 9 3.1.7 Total Organic Carbonand Grain Size of Soil and Sediment..............................10 3.1.8 Water Quality Param eters.................................................................................. 10 3.1.9 Bovine Fecal Samples ....................................................................................... 10 3.2 Biotic Sampling and Tissue A nalysis..............................................................................10 3.2.1 Benthic Macroinvertebrates................................................................................11 3.2.2 M am m al...............................................................................................................12 3.2.3 F is h .......................................................................................................................13 3.2.4 E arth w o rm ..........................................................................................................13 3.2.5 Vegetation............................................................................................................ 14 3.3 Histological assay of small mammal liver and k id n e y ....................................................14 3.4 Toxicity Testing................................................................................................................. 14 4.0 SUMMARY OF PRELIMINARY ECOLOGICAL RISK ASSESSMENT S C R E E N ..............15 5.0 DISCUSSION ................................................................................................................................. 15 SECTION II 1.0 2.0 ECOLOGICAL RISK ASSESSMENT .............................................................................16 INTRODUCTION............................................................................................................................16 1.1 O bjective............................................................................................................................ 16 1.2 Site Background..................................................................................................................16 PROBLEM FORMULATION ............................... 16 2.1 Ecological Risk Assessment ............................................................................................. 16 2.2 Identification of the Contaminants of C oncern.................................................................17 2.3 Exposure Characterization................................................................................................ 17 2.4 Hazard Characterization/Toxicity Assessment................................................................. 17 2.4.1 F lu o rid e ............................................................................................................... 17 2.4.2 Organofluorides...................................................................................................18 2.4.3 Aluminum............................................................................................................. 18 2.4.4 Arsenic ............................................................................................................... 18 2.4.5 B eryllium ............................................................................................................. 19 000005 USFW 0581 2.4.6 Chromium............................................................................................................ 19 2.4.7 C o p p er.................................................................................................................20 2.4.8 I r o n ...................................................................................................................... 21 2.4.9 Lead ................................................................................................................... 21 2.4.10 Manganese ......................................................................................................... 21 2.4.11 Nickel ................................................................................................................. 22 2.4.12 V anadium ............................................................................................................ 22 2.4.13 Zinc ....................................................................................................................23 2.5 Selection of Assessment Endpoints.................................................................................. 23 2.6 Production of Testable H ypotheses.................................................................................. 24 2.7 Conceptual Model ............................................................................................................ 25 2.8 Selection of Measurement Endpoints................................................................... 26 2.9 Life History/Exposure Profile Inform ation......................................................................29 2.9.1 The amphipod (Hyallela azteca) as Representative of Benthic Invertebrates .......................................................................................................... 29 2.9.2 Earthworm (Eisenia foetida) as Representative of Terrestrial Invertebrates ...........

ABD00131709 Ala.

A Section 508-conformant HTML version of this article is available at http://dx.doi.org/10.1289/ehp.1408630.

Volume 6, Number 1 Intldm Naws Features 3 Spotlight 5 News Briefs 7 People 10 People to Watch 10 Sunsets 11 Recent Releases 11 Summer 1994 CHEMSiTAR CARE CHEMSTAR Paneli and Councils Aid Implementation cfResponsible Care The chemical industry as a whole recognizes that th: public perception about the management of chemicals needs improvement After analyzing public opinion and ndustryoperations. industry realized tliat the problem was not perception - il was performance.

I- -J "r 1433, Environmental and Molecular Mutagenesis 21:339-348 (1993) \ Benzene Metabolite, 1,2,4=Benzenetriol, Induces Micronuclei and Oxidative DNA Damage in Human lymphocytes and HL60 Cells Luoping Zhang, Moire 1.

POLYCHLORINATED BIPHENYLS (PCBs) SOURCE IDENTIFICATION October 28,1997 Prepared for PALO ALTO REGIONAL WATER QUALITY CONTROL PLANT 2501 Embarcadero Way Palo Alto, California 94303 (650) 329-2598 By EIP ASSOCIATES 601 Montgomery Street, Suite 500 San Francisco, California 94111 (415) 362-1500 SUMMARY The Palo Alto Regional Water Quality Control Plant (RWQCP) conducted this study to investigate sources of polychlorinated biphenyls (PCBs) in the plant's influent.

664 British Journal of Industrial Medicine 1992;49:664-670 Mortality among firefighters from three northwestern United States cities Paul A Demers, Nicholas J Heyer, Linda Rosenstock Abstract To explore whether exposure among fire fighters to fire smoke could lead to an increased risk of cancer, lung disease, and heart disease, the mortality of 4546 firefighters who were employed by the cities of Seattle and Tacoma, WA and Portland, OR for at least one year between 1944 and 1979 were compared with United States national mortalities and with mortalityofpoliceofficersfrom thesame cities.

9 4 4 TSDR cut v TO* APR 1 m 1991 M.

r-':.ieed is a pi-'cio.cf<U service 5y Pfizer Laccratcr1-- Pfizer L_os PLAINTIFF'S EXHIBIT Viiluineij Iwue 1 PROBLEMS IN MEDICAL PRACTICE Nortin M.

986 F.Supp. 655 Prod.Liab.Rep.

., lead floor sweepings (261.24) containing lead) a.

Zoll presented the proposed principles and advocacy positions and identified three key issues: o Relationship of this issue to Responsible Care and the need to preserve confidentiality to protect audits as a management tool. o More documentation of this type may well lead to more litigation and criminal suits.

Environmental and Molecular Mutagenesis 32:251 -259 (1998) Studies on the Genotoxicity of Molybdenum Salts in Human Cells In Vitro and in Mice In Vivo Nina Titenko-Holland,* Jianhua Shao, Luoping Zhang, Liqiang Xi, Hailong Ngo, Nong Shang, and Martyn T.

Richard Fleming Associates.