An overall look at the data presented in this report leads me to two major observations.

When the findings of the present study are taken in conjunction with the prior demonstration of a mutagenic response via microbial test systems and observations of sig nificant excesses of chromosomal aberrations among workers exposed to VCM, the leading possibility is germ cell damage in the father through direct VCM exposure.

Monsanto MON8ANTO INDUSTRIAL CHEMICALS CO. 800 N.

content might lead to conclusionsabout the behavior of | other PCBs.

Cleary called Moran's discussion of Bailey's qualifications "incredibly misleading," noting that Bailey is a leading expert on noise problems in the textile in dustry and has done experimental noise reduction research on the type of looms in question.

Six,--I could nor help feeling that your otherw-.se well-balanced leading article on this subiecc (30 March, p. 590) tended to oversimplify two problems.

January 13, 1976 of - \/oypvc Messrs J.

Q I will represent to you this istaown as the 51- rr BARGE Triparte agreenent which led to the assignment of the patents and trademarks relating to Limpet and the head licensing agreement leading to the distribution of Limpet from Armstrong Contracting and Supply to Atlas, the Atlas Division of Bell.

In the Marfan syn- drome the spectrum of such lesions ranges from idiopathic dilatation of the pulmonary arteries" and minimal abnormalities of the elastic fibers of the media312-14 to typical CMN.48 Only rarely do such changes overshadow those in the aorta.15-17 Cystic medionecrosis of the pulmonary arteries also occurs in association with long-standing pulmonary hypertension6 and leads occasionally to dissection and rupture of the affected vessels.6,16,ls The rela- tion between pulmonary hypertension and CMN of the pulmonary vasculature remains unclear.

The contractor was asked to identify products containing asbestos, to indicate the form of the asbestos ahd to determine product use patterns which might lead to the release of asbestos fibers.

General Mills is by far the leading supplier of specialty HMA in North America.

A regrind of the parts made initially was reprocessed giving what appeared to be acceptable parts, leading to the tentative conclusion that the problem is one of mastication.

JOSEPH K.

It was agreed any points ob viously unsuitable for program consideration should be omitted, since their very circulation might lead to an erroneous inference, (f iron ind jht lrid ie a: #ath> jis ip- :er< }se: idy ipt. r s< ie U: :es` ;ry lii tU of .is ita : resei lescr: lese fry 1 CMA 040297 PC131-5 Mr.

CHEMICALS RESEARCH FEB0 6 1978 Manufacturing Chemists Association Record of Meeting VINYL CHLORIDE RESEARCH COORDINATORS FK _ OCK _ AJLu .