We have heard that the American Ethyl Corporation are marketing an improved anti knock additive which is a mixture of tetraethyl lead and methyl cyclopentadienyl manganese tricarbonyl.

Inform them that we are participating with the Public Health Service in the recommendation of the Ad Hoc Camittee that: "The Public Health Service, in. collaboration with the manufacturers of tetraethyl lead, the petroleum industry, and other appropriate organizations, conduct studies to provide more definitive data on levels and trends of atmospheric lead contamination in selected urban areas and of the body burden of lead, in selected population groups.

Inform them that we are participating with the Public Health Service in the recommendation of the Ad Hoc Camittee that: "The Public Health Service, in. collaboration with the manufacturers of tetraethyl lead, the petroleum industry, and other appropriate organizations, conduct studies to provide more definitive data on levels and trends of atmospheric lead contamination in selected urban areas and of the body burden of lead, in selected population groups.

ear - .r# Francis* 1 vac -shed to avalute Mr* st the request of Dr* 0. ..r-.rDimgfe becuna of of chronic load in** toxicstion due to exposure to tetraethyl lead during this nan* 3 employment with the vhmderlich Corporation X first suw the patient in my office on Hcvebfoer 105 1X62* siuix 1 r iHSHExy cehfLiXKxsi 1) ins patient first consulted his 1 .li.X* 1 hr* Pedro vilo&rm&vs, eff 1612 ocyth Fvans streett fan d i o s o 13 t in anu&ryt 1962 vltla a; *ve^/3 of-tinnitus in both ,,; r:; and fronts!

A governmental Commission,having issued a report on tetraethyl lead (confirming our findings for local consumption), is in no hurry (understandably) to take any further action, and so there will be David E.

It is known that some substances in our environment; for example; 2-naphthylamine and tetraethyl lead are converted to carcinogenic compounds.

Gallon 2.46 ccs of T.M.L. per Imperial Gallon /2 2 < We enclose copy of this letter so that - ou if you wish forward it to Petroleum Section* ' there be any additional information which they rucuro#no t orT'^ you will Jet us hnowr. *' In reply to the last paragraph of your letter r-o confirm that the anti-knock compounds contained in Tetraethyl Load and anti-knock compounds contained in TetraMethyl Lead are the only anti-knock agents which w/c- currently supply* Tours very truly.

No case of tetraethyl lead poisoning has occurred among the thousands of persons who have trans ported and

It shows that experimental study of tetraethyl lead began in the U.

I LI A23769 black oxides lead silicates lead chrvmaies and tetraethyl lead to name only thr* more important few The other 60 per cent of the lead consumed is largely in metallic form either as pore lead or an alloy,i Among the more important pnwfucm in this group are a lora (p* battery grids cable sheathing ammunition pipe sheet solder, babbitt, type metal calking lead and many others t think here Itreakdown of the consumption of lead in 1962, in terms of the re sultant products may be enlightening This is given in the following (able t.e^d (Consumption fly Products 1V62 iKst / tin Shoil Tonal Tetraethyl 1< ad 172 000 Litharge 87 000 Mlark Oxide test t Hrd lead Khile lead 150 000 21000 n ooo Lead c hn*male* 20 000 Lead arsenate 2 300 I Miscellaneous lead compounds 6 000 Total lead compounds 471 500 Antimonial lead products 190.000 Cable sheathing 56 000 Solder 63 000 Calking lead 73 000 Ammunition 47.000 Pipe and extruded products 20 000 Moiled pioduc ts 30.000 1 Type metal 27.000 Beanng metals 17 000 Miscellaneous 82 S00 Total metallic products 605 500 TOTAL 1,077,000 Another way to break down these consumption figures is by industries rather than by product* fthile it is difficult to make a clesr-cui separation in thia respect, it is probably s more interesting and valuable breakdown fnxn many standpoints.

The interesting thing however is the variety of industries and variety of prod ucts into which this tonnagr of lead enters In the first place over 40 percent of all the lead used last year went into chemical compounds like *hite lead red lead, litharge, IJ-2 * a.-1 LIA23769 black oxide* lead silicate* lead chrvmates and tetraethyl lead !

The interesting thing however is the variety of industries and variety of prod ucts into which this tonnagr of lead enters In the first place over 40 percent of all the lead used last year went into chemical compounds like *hite lead red lead, litharge, IJ-2 * a.-1 LIA23769 black oxide* lead silicate* lead chrvmates and tetraethyl lead !

The work of the first summer, carried out in the Dayton plant, resulted in a clinical characterisation of tetraethyl lead poisoning, a preliminary and rough interpretation of the nature and the approximate order of magnitude of the hasards of handling tetraethyl lead and certain halogen carriers, and the develop ment of certain principles for the oontrol of the hasards.

Infra-red irradiation effect on skin pigmentation Insecticides microchemical detection Insects necrotic bite of brown recluse spider Lead analytical methods for determination atmospheric concentration determination self-powered portable sampler epidemiology of disease associated with importance and uses of metabolism under abnormal conditions nature of in exhaust gases natural occurrence normal metabolism 498 458 476 476 454 444 443 425 491 487 431 504 425 451 502 447 466 515 501 469 461 468 498 462 467 Lead poisoning clinical inorganic in children problems in recognition 470 471 472 Lead tetraethyl absorption and pathology determination in air hygiene and medical control procedures intoxication 465 501 463 464 Lead tetramethyl absorption and pathology determination in air 465 501 Leukemia complicated by fungus infection 444 Light abnormal reactions of man to 445 kasala), mechanical properties in men over 60 particle deposition by diffusion 438 483 Magnetic fields effect on organism 493 Microchemical detection of airborne toxic agents 502 New England history and problems of occupational health 517 Occupational health history and problems in New England 517.

It does occur occa sionally from exposure to tetraethyl lead or lead fumes.