Comment on Proposed Restriction of PFAS Aug 25, 2023 Japan Valve Manufactures' Association (JVMA) Japan Valve Manufacturers Association (JVMA) appreciates the opportunity to provide comments to the PFAS restriction proposal. 1.

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Assogomma comments on the Annex XV Dossier of the universal PFAS restriction proposal September, 6th 2023 1 1.

Submission Consultation on the Annex XV restriction report on the restriction on the manufacture, placing on the market and use of PFASs CHEM Trust general comments and additional supporting evidence September 2023 General comments CHEM Trust would like to thank the authorities from Denmark, Germany, the Netherlands, Norway, and Sweden for preparing this comprehensive restriction proposal.

Chemours Thermal & Specialized Solutions (TSS) contribution to the universal PFAS restriction ECHA Public Consultation 21 September 2023 Attachment 3 Table of Contents Annex I: Annex II: Annex III: Annex IV: Annex V: Complement to the information presented in Attachment 1 Chapter 1 - Go to Page Specific comments and observations on Annex A of the PFAS restriction dossier - Go to Page Comments on the analytical methods described by the Dossier Submitters in Annex E of the PFAS restriction dossier - Go to Page Socio-Economic Analysis and Impact Assessment of a potential REACH Restriction on F-gases as PFAS, report for Chemours Thermal Specialized Solutions (TSS) [attached in confidential version] - Go to Page Evaluation of Costs based on Restriction Derogations for Mobile Air Conditioning Maintenance - Go to Page Annex I: Complement to the information presented in Attachment 1 Chapter 1 Supporting information - Attachment 1, Section 1.2 Table 1 - Summary of available toxicity data for TSS substances and TFA Attribute Substance Name EC Number CAS Number Occupatio nal Exposure Limit Acute Inhalation Lethality HFO-1234yf 2,3,3,3tetrafluoropr opene 468-710-7 754-12-1 500 ppm (8hr TWA) TERA WEEL 4-hr LC50 > 405,000 ppm (> 1887 mg/L), rat 1-hr NOAEC > 100,000 ppm (> 466 mg/L), rabbit HFO1336mzz- E (2E)1,1,1,4,4,4 Hexafluoro but-2-ene 811-2130 6671186-2 400 ppm (8-hr TWA) TERA WEEL 4-hr LC50 > 17,000 ppm (> 114 mg/L), rat HFO1336mzz- Z (2Z)1,1,1,4,4,4 Hexafluoro but-2-ene 700-6517 692-49-2 500 ppm (8-hr TWA) TERA WEEL 4-hr LC50 > 102,900 ppm (> 690 mg/L), rat HFC-134a HFC-125 HFC-143a HFC-152a 1,1,1,2tetrafluoroe thane 1,1,1,2,2pentafluoroe thane 1,1,1trifluoroeth ane 1,1difluoroeth ane 212-377-0 811-97-2 206-557-8 354-33-6 206-9965 420-46-2 200-8661 75-37-6 OCCUPATIONAL EXPOSURE LIMITS 1000 ppm (8-hr TWA) - TERA WEEL 1000 ppm (8-hr TWA) TERA WEEL 1000 ppm (8-hr TWA) - TERA WEEL 1000 ppm (8-hr TWA) - TERA WEEL ACUTE TOXICITY 4-hr LC50 > 359,300 ppm (> 1500 mg/L), rat 4-hr LC50 > 800,000 ppm (> 3927 mg/L), rat 4-hr LC50 > 591,000 ppm (> 2030 mg/L), rat 4-hr LC50 > 437,500 ppm (> 1182 mg/L), rat HFC-227ea 1,1,1,2,3,3,3heptafluoropr opane 207-079-2 431-89-0 No data 4-hr LC50 > 788,696 ppm (> 5485 mg/L), rat HFC4310mee 1,1,1,2,2,3,4, 5,5,5decafluorope ntane 420-640-8 138495-428 225 ppm (8hr TWA), 700 ppm (15-min STEL) TERA WEEL 4-hr LC50 > 359,300 ppm (> 1500 mg/L), rat TFA Trifluoroacet ic Acid 200-929-3 76-05-1 4-hr LC50 > 64 ppm (> 0.3 mg/L), rat Acute Cardiac Sensitizati on Dermal Irritation Eye Irritation Skin Sensitizati on In vitro In vivo Inhalation Oral NOAEL = 120,000 ppm LOAEL > 120,000 ppm None None None Negative (mutagenicit y & clastogenicit y) Negative (clastogenici ty) 13-week NOAEC = 50,000 ppm, rat* 4-week NOAEC = 10,000 ppm, minipig* 4-week NOAEC = 500 ppm, rabbit Not a relevant route of exposure.

Background on Semiconductor Manufacturing and PFAS Semiconductor PFAS Consortium May 17, 2023 Acknowledgments: The consortium would like to acknowledge the contributions of the Semiconductor PFAS Consortium for their efforts to compile this information.

Comments on the PFAS European Restriction ProposalFinal Draft Director, Material Industries Division, Manufacturing Industries Bureau, Ministry of Economy, Trade and Industry of Japan is closely following ECHA's proposed restriction for perfluoroalkyl compounds and polyfluoroalkyl substances (PFASs), published on March 22, 2023, and would like to submit the following comments for consideration and appropriate action.

Processed Product for Food Contact Materials and Packaging Materials Application Number: Food contact materials and packaging materials (Annex E.2.3) Materials used in this product is PTFE (CAS NO: 9002-84-0), PFA (CAS NO: 2665500-5), and PVDF (CAS NO:24937-79-9).

Brussels, September 23rd, 2023 EFCG response to the ECHA consultaon on the proposed restricon on the manufacture, placing on the market and use of per- and polyfluoroalkyl substances (PFAS) The European Fine Chemicals Group (EFCG), a sector group of Cefic1, represents the European manufacturers of Acve Pharmaceucal Ingredients (APIs), their pharmaceucal intermediates and excipients.

Assogomma comments on the Annex XV Dossier of the universal PFAS restriction proposal September, 6th 2023 1 1.

SAFER STATES AND SIGNATORY COMMENTS ON ECHA PFAS RESTRICTION PROPOSAL Safer States is submitting the following comments in strong support of the proposed restriction of per- and polyfluoroalkyl substances (PFAS) on behalf of the following 19 organizations based in the United States (US): Alaska Community Action on Toxics, Alliance of Nurses for Healthy Environments, Center for Environmental Health, Clean and Healthy, Clean Cape Fear, Clean Water Action, Consumer Reports, Defend Our Health, Earthjustice, Ecology Center, Great Lakes Regional Center of the National Wildlife Federation, Merrimack Citizens for Clean Water, North Carolina Conservation Network, Oregon Environmental Council, Responsible Purchasing Network, Safer States, Vermont Conservation Voters, Vermont Natural Resources Council, Women's Voices for the Earth.

U.S.

Draft agenda for PFAS-RESTRICTION WEBEX Meeting between DE, DK, NL, NO, SE CA and ECHA 22 June 2020, 9 am --1 pm (CET) Login details: ECHA Risk Management invites you to join this Webex meeting.

Apr 25, 2023 Comment on Proposed Restriction of PFAS Conference of Fluoro-Chemical Product Japan (FCJ) On behalf of chemical manufacturers, we, Conference of Fluoro-Chemical Product Japan (FCJ), have been working tirelessly to comply with national chemical regulations.

Apr 25, 2023 Comment on Proposed Restriction of PFAS Conference of Fluoro-Chemical Product Japan (FCJ) On behalf of chemical manufacturers, we, Conference of Fluoro-Chemical Product Japan (FCJ), have been working tirelessly to comply with national chemical regulations.