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AR226-2292 ' ' Chris E Shoop 10/17/200210:07 -":::'::;^^;N%^^i;%i:-'; AM____________________ To: Robert LRitchey/CUDuPontQDuPont CK Oscar T Gaiza/ABDuPont@DuPonl, Ta-Wei Fu/SBDuPont@DuPont, Fred M Lentz/SE/DuPont@DuPont, Kari G Kronberg/AE/DuPon@DuPont,Debbie J Mulrooney/AE/DuPont@DuPont, Robert I Wevodau/SE/DuPont@DuPonl Subject Explanation ol Input Data far Modeling Studies Bob.

AR226-2552 -^ Washington Works EPA/COE Update Meeting July 18, 2002 Agenda Background/Receat Project Activity - RCRA Program Status - Multi-Media Consent Order Update - GW Modeling Project Review Preliminary GW Modeling Res RCRA Program Path Forward - RFI Report/EPA Review -El Status Meeting Objectives Provide brief overview of recent MMC activity at Washington Works Re-assess where we stand with regard t EPA Region HI RCRA program, determ next steps (i.e., RFI, EJ.s) Receive technical feedback from EPA/C on the newly constructed Wash Works Flow Model ^K Background/Recent Activi RCRA Program Status - EPA reviewing RFI report - C-8 screening levels needed for completio --- El evaluation also on hold pending C-8 screening levels - Ongoing GW Modeling project will addre EPA/COE 2001 comments on 1999/RFI version of GW Model Background/Recent Activi Multi-media Consent Order (WVDEP) Required Elements: - Toxicology/CAT: Develop RBC-Like screening levels for dw, soil, and air - GW/SW Investigation/GIST: Determme in groundwater & surface water at/near sit - Cap/reduce emissions to air & sw CAT Highlights Toxicology team met May 5-7.

AR226-2565 EGA Technical Subgroup Monitoring Landfill Monitoring and Exposure Summ Goal for Today Understand the contribiition of landfills PFOA levels in the environment Environmental Assessment F Manufacturing Facilities/Land 1.

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AR226-2700 AR226-2700 TORONTO WORKSHOP MATERIALS September 13-14,2004 John Gannon DuPont Central Research & Develop Wilmington, DE of in the Is the Sources?

AR226-2921 FOR DU FONT USE ONLY cc; Haskell E.

AR226-3063 DuPont HLR 903-96 HASKKLXi XABOXXTOX?

AR22G - 3272 454 ARage _ 3274 DuPont9478 --~ `TRADE SECRET Study Title (OY ric Tosicty '90-Day Oral Gavage Study in Rats Volume 1of3 - Laboratory Project ID: DuPont-9478 "Test GUIDELINES: U.S.

Mars. 3279 oi 7 5125025: Developmen Tosi Sty nats. ~ TRADE SECRET AR226_ 3279 Dwei13 Study Title H-25425: Developmental Toxicity Study in Rats Laboratory Project ID: DuPont-11347 TEST GUIDELINES: U.S.

AR A426 - 332] 503 AR226_ 332 Dupont13830 --~ TRADE SECRET Study Title H-25425:Repeated-DoseDermal Toxicity 28-Day Study in Male Rats TesT GUIDELINES: U.S.

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CorporateHealth Physics Corporate OccupationalMedicine Corporate ProductResponsibility Corporate Toxicology 3M MedicalDepartment 3M Center,220-2E-02 PO Box 33220 St Paul,MN 55133-3220 651733 1110 An Epidemiologic Investigationof ClinicalChemistries,Hematology and Hormones in Relation to Serum Levels of PerfluorooctaneSulfonateinMale Fluorochemical Production Employees Following reportsof the findingof organicfluorineinserasamples,a fluorochemical medical surveillancperogram began at3Ms Decatur manufacturingfacilitiynthe late 1970's.The surveillancperogram has generallyconsistedofannual or biannualtestsof clinicaclhemistriesp,ulmonary function,blood countsand a biomonitorof fluorochemicalexposure.

Study Plan aerobicac soil/sedim fluorochert m --. -- StudyDesigns- 3M MicrobiaMletabolismProgram Goal:To optimizeconditiontshatpermitenrichmentofmicrobial populationcsapableofmetabolizinfgluorochemicals.

MICROBICS MICROTOX@) TOXICITY TEST TEST SUBSTANCE Identity:Perfluorooctanoiaccid,ammonium salt;may also be referredto as PFOA ammonium salt,Ammonium pernuorooctanoate,PFO, FC-1 16, FC-1 26, FC-1 69, FC-1 43, or as a major component of FX-1003.