26 _ 06& T BIODEGRADATION (BOD/COD) TEST SUBSTANCE _________________________________________ Identity: A mixture containing perfluorooctanesulfonate; may also be referred to as PFOS, FC-95, or as a component of FC-185F. (1Octanesulfonic acid) (CAS # 2795-39-3) Rem arks: The 3M production lot number was 1-2303.

AR &Z& - 0 7 8 / ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE____________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-206 or L3243. (1-Octanesulfonic acid) (CAS # 2795-39-3).

iogr~ 3M Company EPI-OOli Page 1 of 42 FINAL REPORT Epidemiology Medical Department 3M Company St.

Telom er Research Program AR226-1425 Report Title: 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoroFish (Zebrafish), Acute Toxicity Test, Static, 96h, Limit Test with the Water Accommodated Fraction (WAF) RECEIVED 2003 July 18 12:00PM Author(s): Dirk Scheerbaum Contractor: Dr.

AR226-1536 The MSDS format adheres to the standards and regulatory requirements of the United States and may not meet regulatory requirements in other countries.

1' 2-41 E .

E*-0I2 e v *.*0 ctuiLiiM ioits: E.

received OPPT HCIC ^ HAY200 i 2 4i1 9: j q ^ Study Title T e n n e s s e e R iv e r V a ll e y S a m p le s 26" 1733 Author Mark E.

Study Title ORAL (GAVAGE) TWO-GENERATION (ONE LITTER PER GENERATION) REPRODUCTION STUDY OF AMMONIUM PERFLUOROOCTANOATE (APFO) IN RATS SPONSOR'S STUDY NUMBER: T-6889.6 Data Requirement U.S.

3M Medical Department Study: T-6295.22 Analytical Report: FACT-TOX-160 LIMS E00-1668 3M Medical Department Study: T-6295.22 Analytical Report: FACTTO X-160 M S E00-1668 Study Title Extended Recovery Study Following a 26-Week Capsule Toxicity Study (FACT-TOX-030) with Perfluorooctane Sulfonate Acid Potassium Salt (PFOS; T-6295.22) in Cynomolgus Monkeys Analytical Laboratory Report Title Determination of the Presence and Concentration of PFOS in Serum and Liver Samples of Cynomolgus Monkeys Data Requirement Not Applicable Author 3M Environmental Laboratory Study Completion Date May 3, 2002 Performing Laboratories Sera and Liver Analyses Sera and Liver Extractions 3M Environmental Laboratory Building 2-3E -09,935 Bush Avenue St.

T-6295.28 Final Report T-6295.28: Analysis of Liver Enzymes, Glycogen, and Perfluorooctane Sulfonate (PFOS) Concentration in Samples from T-6295.25: One-Generation Reproduction Study of PFOS - Mevalonic Acid/Cholesterol challenge and NOEL Investigation in Rats.

3M Environmental Technology and Services PO Box 33331 St.

PiR11-OM30 CO RN ING Hazleton MUTAGENICITY TEST ON T-6564 IN AN IN VIVO MOUSE MICRONUCLEUS ASSAY FINAL REPORT AUTHOR Hemalatha Murli, Ph.D.

Attachments to Letter to C.

Attachment II DuPont Statistical Analysis of Serum Lipid Data of Miteni Workers Confidential DuPont Draft Work Product Confidential DuPont Draft Work Product Confidential DuPont Draft Work Product LO G _LD L vs LO G _PFCV\ : 2 0 0 4 3. s.s 3.4 Slcpe p --m lu e LOG_P FOA = Q 02 5.5 $.2 t * S.1 m ft D O"u*1A*i1 J 4.z 4.7 4.44.5 4.4 4.5 4.2-1 .* * dI Z3 LPE-FfM LDG _LDL vs LO G _PFC A : 2 0 0 3 3.4 S.S Slope p --m lue LOS PFOA = 0.83 S.2 S.1 * 3.3 a 4.4 U 3 44 ^ 4.7 4.4 4.4' p V 4.4: 4,41 0 IZ3 L&E.FFDA 4 * 4 L O G _ L D L v s L O G _ P F Q fli : 2 0 0 2 3.1- 5.5- 3.7' Slope p--value LOG_PFCA = 0.07 5.5- 5.53.45.3- 5.1- , wm a r m . 3 5,0t.4.5 4.7 4.5 4.54.44.3- 1 * 1 1 ' ill"1 p * p i s -l -1 4 1 Z i 10C-PFM .* P * ft 45 L O G _ L D L v s L O G _ P F Q fli : 2 0 0 1 5.*- 5.3Slope p --value LOG PFCA = 0 .6 4 5.Z- * * mm m . m 3.1: 3.D o 4 .$ 1 3+5: 4.7: 4 .