t I I --FORDfU PON'TUSE ON"LY1 AR226-2915 E.

DuPont HLO 504-96 WHITE EAGLE TOXICOLOGY LABORATORIES 2003 Lower State Road, Doylestown, Pennsylvania 18901 Telephone: (215) 348-3868 __________________ Fax: (215) 348-5081 _____________ AR226-3055 Study Title Guinea Pig Dermal Sensitization - Modified Buehler Method with H-21891 Laboratory Project TD Haskell Laboratory Project ID 504-96 Data Requirement EEC 92/69 - Annex V - Part B.6 (1992) - 93/21 (1993), OECD Guidelines for Testing of Chemicals, No. 406, Skin Sensitization, adopted July 17, 1992 , U.S.

AR226-3087 DuPont H LQ -1998-00730 TRADE SECRET Study Title Acute Dermal Irritation/Corrosion Study with H-22482 in R abbits FINAL REPORT Haskell Laboratory Project ID : H LQ -1998-00730 Perform ing Laboratory Project ID : W IL-189161 Data Requirement Organization for Economic Cooperation and Development (OECD), Part 404 (1992) European Economic Community (EEC) 92/69 Annex V - M ethod B4 (1992) A uthor Tom G.

AR226-3113 Huntingdon / PHYSICO-CHEMICAL PROPERTIES Sponsor DuPont Specialty Chemicals Jackson Laboratory Chambers Works Deepwater NJ 08023 USA Research Laboratory Huntingdon Life Sciences Ltd.

AR226-3116 unting pgi 4i=>/ytad!

Haskell Laboratory for Toxicology and Industrial Medicine January 4,2002 AR226-3215 TO: ilot Developmental Toxicity Study in Rats cc: L.

AR226-3382 HASKELL LABORATORY Common Name: Telomer B Citrate Urethane (TBCU) Chomir.al Name: Poly(difluoromethylene), alpha-fluoro-omega-(2-hydroxyethyl)-, ester with 2,15 -bis(carboxymethyl)-4,13-dioxo-3,14-dioxa-5,12-diazahexadecane1,2,15,16-tetracarboxylic acid CAS Registry No.: 65530-58-7 Chemical Structure: ,o Rf-- CH-2-- CH20-- O - C O CH_ O Il I * II Rf-- CH,-- CH,-- O-C -- C-O-C-NH I -(CH,,2)' 3 CH,, R-f-- CH_2-- CH20-- O -- C,, 0 where Rf = H r CF^~ CF2-- ^ F Physical Properties: Form: Molecular Weight: Boiling Point: Melting Point: Density: Brown solid Approximately 3200 (typical grade) 1.5 g/mL Recommended AEL 0.1 mg/m3 (8- and 12-hour TWA), respirable dust General Toxicity TBCU has very low acute oral toxicity with an ALD in the rat of 25 grams/kg (DuPont, 1976a).

AKA _ m -o r 9 000130 Aknas- zvof s T itle: Bioanalytical Method Validation for the Quantitation o f Perfluorooctanoic A dd in Human Serum A uthors: David J.

M 000368 AR R6- `f-3 * ' TABLE II GC PRECISION SAMPLE 5 ppm FC-143 1,0 ppm FC-143 0,5 ppm 0,25 ppm GC COUNTS/THOUSANDS 232.5, 241.0, 234.1 63.2, 62.3, 65.2, 61,6, 59.0 33.4, 34,3, 38.8, 39.5 17.5, 15.5, 19.1, 18.4 SAMPLE 1 2 3 4 5 6 7 8 9 10 BLOOD SAMPLES ILC with PPD/S.

fatseULG-- li-37 u>o 000382 A. t 47 Rr.'

3M Corporate Toxicology and Regulatory Services 3M Center, Building 0220-06-E-03 St.

Federal Register/Vol. 71, No. 1 9 /Monday, January 30, 2006/Notices 4913 SUMMARY: The EPA Science Advisory Board (SAB) Staff Office announces a public teleconference meeting of the chartered SAB to discuss a draft SAB report, EPA's Draft Risk Assessment of the Potential Human Health Effects Associated with Exposure to Perfluorooctanoic Acid (PFOA): A Review by the PFOA Review Panel of the EPA Science Advisory Board.

%>G& P-1 3M Company EP [-0027 Page l o f 20 Date: January 9, 2006 Final Report Epidemiology, 220-6W-08 Medical Department 3M Company St.

3M Katherine E, Reed.

Andrea V.