/ N frU -0 5 2 .5 ACUTE TOXICITY TO FISH TEST SUBSTANCE_______________________________________________ Identity: Perfluorooctanoic acid, ammonium salt; may also be referred to as PFOA ammonium salt, Ammonium perfluorooctanoate, PFO, FC116, FC-126, FC-169, FC-143 or as the major component of FC1015.

$X )ltrO % t Analytical Laboratory RepSotrutdoyn PTritelseence and Concentration of Potassium Perfluorooctanesulfonate in Serum and Liver of Sprague-Dawley Rats Exposed to PFOS via Gavage REPORT AMENDMENT NO. 1 Am1e9nAdpmrieln2t00D0ate: Performing Laboratory 3M Environmental Technology & Safety Services 3M Environmental Laboratory 935 Bush Avenue St.

<gHQ - oy-06. 373 {oz>o g/l7g,a z ) _________________ ________________________________________________ &o A R Z O fc -a W Analytical Laboratory Report ON THE Determination of the Presence and Concentration of Perfluorooctanesulfonate (PFOS) (CAS Number: 2759-39-3) in the Serum of Sprague-Dawley Rats Exposed to Potassium Perfluorooctanesulfonate via Gavage Laboratory Report No.

AAA6-0679 MULTI-CITY STUDY FINAL FIELD REPORT FOR COLUMBUS GEORGIA AND PORT ST.

M A 2 6 - 07/6 ACUTE TOXICITY TO FISH (BLUEGILL SUNFISH) TEST SUBSTANCE____________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-203. (1Octanesulfonic acid) (CAS # 2795-39-3).

fiKSLS.6 - O Z 2 9 ACUTE TOXICITY TO AQUATIC INVERTABRATES (DAPHNIA MAGNA) TEST SUBSTANCE____________________________________________ Identity: A mixture containing periluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-600. (1-Octanesulfonicacid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The 3M production lot number was not noted.

AR - 09/7 TO XICITY TO AQUATIC PLANTS TEST SUBSTANCE Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FX-3104. (1Octanesulfonic acid) (CAS # 2795-39-3).

NORTHERN KENTU CKY OFFICE SU IT E 340 DIXIE HIGHWAY O V IN G T C N K E N T U C K Y 4 - : * * - i :D4 6C6-331-2938 5 13-381-2938 FAX 513-381-6613 R o b e r t a .

R a - H - I3S"^ Page 1 FINAL REPORT Epidemiology, 220-3W-05 Medical Department 3M Company St.

AR226-1379 m A9.6 _ /3 7 7 CC: B.

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^ 4 2 2 - V / 7 6 CANCER PREVALENCE IN SUBJECTS EXPOSED TO PERFLUOROOCTANONIC ACID (PFOA) James Dahlgren MD1, Ayman B Ibrahim M DU' \Raphael Warshaw2, Harpreet Takhar MPH3 1.

ACUTE TOXICITY TO BLUEGILL SUNFISH TEST SUBSTANCE______________________________________________ Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The test substance is a white powder (3M Lot 583) of uncharacterized purity.

/IRlK-O%& 3M MEDICAL DEPARTMENT TOXICOLOGY SERVICES To: Geoijean Adams 290-4-01 cc: John ButenhofF 220-2E-02 From: Marv Case 220-2E-02 Subject: FC 95 and 143 Teratology Date: 26 May 1998 John passed on to me your request for someone to review and write an analysis on the eye lens defect that was reported in the original FC 95 rat teratology study.

'he -` Oeeiei'ie t H i e /jienM iu A < lu. 1 12 b v 1 ; A ' - i-,; bNcvicr Seif net Publishers B V All nnhis reserved <XI()5-27(i<l/9;/S(jyiXl B13ALIP 54011 N 'C ;-- a " ': --p--s A.-,..-*-: -'-I The mechanism underlying the hypolipmie effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid Bente Haughom and 0ystein Spydevold Institute o f Medical Biochemistry, Universi!}