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/VUA6 _ 134-6 Telomer Research Program V ^ Clariant Report Title: Purified 8-2 Alcohol: Salmonella - Escherichia co///M ammalian - M icrosome Reverse Mutation Assay with a Confirmatory Assay Author(s): Leon F.

\ IN WATER (3/15/84) and (6/4/84) o '1 CO LOCATION .

SAMPLING INVESTIGATION RESULTS LITTLE HOCKING WATER ASSOCIATION WELL FIELD WASHINGTON COUNTY, OHIO Date: April 2003 Project No.: 7482 18983762.00010 A CORPORATE REMEDIATION GROUP An Alliance between DuPont and URS Diamond Barley Mill Plaza, Building 27 Wilmington, Delaware 19805 00030J.

S R P T T -74H MIN 315/022356 PERFLUOROOCTANESULFONYL FLUORIDE (POSF) T 'lf c ^ l.3 IN VITRO M AM M ALIAN CHROM OSOM E ABERRATION TEST IN HUMAN LYM PHOCYTES Sponsor 3M Center 3M Corporate Toxicology Building 220-2E-02 St Paul MN 55133-3220 USA - n e /sc-i Page 1 of 31 Research Laboratory Huntingdon Life Sciences Ltd Woolley Road Alconbury Huntingdon Cambridgeshire PE28 4HS ENGLAND Report issued 22 October 2002 MIN 315/022356 CONTENTS Page CONTENTS................................................................................................................................. 2 COMPLIANCE WITH GOOD LABORATORY PRACTICE STANDARDS....................... 4 QUALITY ASSURANCE STATEMENT................................................................................. 5 RESPONSIBLE PERSONNEL.................................................................................................. 6 SUMMARY................................................................................................................................. 7 INTRODUCTION........................................................................................................................ 8 TEST SUBSTANCE.................................................................................................................... 10 EXPERIMENTAL PROCEDURE.............................................................................................. 11 ASSESSMENT OF RESULTS................................................................................................... 15 MAINTENANCE OF RECORDS............................................................................................. 15 RESULTS..................................................................................................................................... 16 CONCLUSION............................................................................................................................ 17 REFERENCES............................................................................................................................. 18 : 2: MIN 315/022356 COMPLIANCE WITH GOOD LABORATORY PRACTICE STANDARDS The study described in this report was conducted in compliance with the following Good Laboratory Practice standards, with the exceptions stated below, and I consider the data generated to be valid.

.Wildlife International Ltd. -1 - Project Number 454A-1Q2 PFOS: A 96-HOUR STATIC ACUTE TOXICITY TEST WITH THE FATHEAD MINNOW (Pimephales promelas) ADDENDUM WILDLIFE INTERNATIONAL, LTD.

Study No.

3M General Offices mH?

Larry R.

FROM LATHAM & WATKINS WASH DC #3 (THU) 4. 27'00 12:11/ST. 12:06/NO. 4261478959.

SRPT T-6295.8, T-6316.4, T-6868.2, T-7071.1, T-7132.1 DT15-B 3M MEDICAL DEPARTMENT, CORPORATE TOXICOLOGY Title: Comparative Molecular Biology of Perfluorooctanesulfonate (PFOS, T-6295), N-ethyl perfhiorooctanesulfonamido ethanol (N-EtFOSE, T-6316), N-Ethyl perfluorooctanesulfonamide (N-EtFOSA, T-6868), Perfluorooctanesulfonamido acetate (FOSAA, T-7071), and/or Perfluorooctanesulfonamide (FOSA, T-7I32) of in Rats and Guinea Pigs following Oral dosing.

Katherine E.

AtL22rtf(>8 Bladder Cancer in Perfluorooctanesulfonyl Fluoride Manufacturing Workers Final Report Bruce H.

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