3M ENVIRONMENTAL LABORATORY REPORT NO.

INTERIM REPORT # 6 - Analysis of Liver and Serum Samples STUDY TITLE Analysis of Perfluorobutanesulfonate (PFBS), Perfluorohexanesulfonate (PFHS), and Perfluorooctanesulfonate (PFOS) in Water, Soil, Sediment, Fish, Clams, Vegetation, Small Mammal Liver and Small Mammal Serum Using LC/MS/MS for the 3M Decatur Monitoring Program DATA REQUIREMENTS EPA TSCA Good Laboratory Practice Standards 40 CFR 792 STUDY DIRECTOR Jaisimha Kesari P.E., DEE Weston Solutions, Inc. 1400 Weston Way West Chester, PA 19380 Phone: 610-701-3761 INTERIM REPORT COMPLETION DATE April 23, 2008 PERFORMING LABORATORY MPI Research, Inc. 3058 Research Drive State College, PA 16801 Phone: 814-272-1039 STUDY SPONSOR 3M Company 3M Building 0236-01-B-10 St.

3M General Offices 3M Center St.

3M General Offices 3M Center St.

i /[R 2 1 6 -0 4 5 H 3M Environmental Laboratory Final Report- Analytical Study Single-Dose Dermal Absorption/Toxicity Study of T-6067, T-6068 and T-6069 in Rabbits In-Vivo Study Reference Number: HWI#6329-152 Study Number: A M D T-011095.1 Test Substance: L -13492 (T-6067, T-6068 and T-6069) Name and Address of Sponsor: 3M SCD Division 367 Grove Street St.

NORTHERN KENTUCKY OFFICE SUITE 340 1717 DIXIE HIGHWAY COVINGTON.

MX.Z6 _ 134-7 RECEIVED OPPTHCIC rTelomer Research Program jjfsrI r VVVii ASAMK.I.*?

Telom er Research Program AR226-1426 Report Title: 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoroRespiration Inhibition Test with Activated Sludge Author(s): Martina Noack RECEIVED OPPT NCIC 2003 July 18 12:00PM Contractor: Dr.

Eiviraimeitaif News AR226-1529 Potential explanation for fluorinated compounds' persistence The first assessment of the atmos pheric lifetime of an important class of fluorinated chemicals, ducers.

AR226-1750 PFOS: A PILOT REPRODUCTION STUDY WITH THE NORTHERN BOBWHITE FINAL REPORT WILDLIFE INTERNATIONAL, LTD.

AR226-1751 STUDY TITLE Extraction of Potassium Perfluorooctanesulfonate from Quail Serum and Quail Liver for Analysis Using HPLC-Electrospray/Mass Spectrometry DATA REQUIREMENTS Analytical Method Requirements STUDY DIRECTOR Sean Gallagher STUDY COMPLETED ON September 06, 2001 PERFORMING LABORATORY / TESTING FACILITY Centre Analytical Laboratories, Inc.

3M FLUOROCHEMICAL SUBMISSIONS February, 2002 - May, 2004 INDEX OF 3M'S 2002-2004 AR-226 DOCKET SUBMISSIONS BY DATE Back to Menu DECEMBER 2002 Click on Study Title to View Report December 16, 2002 December 16, 2002 Submission Cover Letter Biodegradation Study Report: Biodegradation Screen Study for Telomer Type Alcohol, Pace Analytical Services, Inc.

3M FLUOROCHEMICAL SUBMISSIONS February, 2002 - May, 2004 INDEX OF 3M'S 2002-2004 AR-226 DOCKET SUBMISSIONS BY DATE Back to Menu January 2004 Click on Study Title to View Report January 8, 2004 January 8, 2004 Submission Cover Letter Final Report, PFOA: Lactational and Placental Transport Pharmacokinetic Study in Rats, DuPont Haskell Laboratory Project No.

3M Company Page 1 of 121 FINAL REPORT Epidemiology, 220-3W-05 Medical Department 3M Company St.

Estrous Cycling and Natural Delivery/Litter Observation Data FI Estrous Cycling Data, From Data Analysis Presented at EPA on August 30,2002" APFO Dose Group (mg/kg/day) 0 1 3 10 30 All 4-Day 14/30 19/29 9/30 15/29 15/30 Cycles 3-5 Day Cycles 24/30 26/29 21/30 25/29 27/30 Cycle Length (Days) 2 3 4 5 6 7 8 Mean Cycle Length (Days) S.D. 1 2 75 18 5 1 2 4.3 0.8 Incidence of Cycle Length Per Group 0 1 80 16 2 1 0 4.2 0.5 5 7 57 32 5 0 1 4.3 0.9 2 5 84 14 3 0 0 4.1 0.6 5 5 86 17 0 0 2 4.1 0.8 Aberrant Cycles Parental > 4 Days Diest. 2 1 14 1 > 3 Days Est. 17 13 15 16 13 FI > 4 Days Diest. 5 3 3 5 3 > 3 Days Est. 25 25 29 11 14 P E M D End in Estrous Distribution of Cycle Status at Start of 21-Day Evaluation Period, FI 14 12 8 10 11 14 6220 15 13 16 13 Distribution Rats in Estrous at End of 21-Day Evaluation Period, FI 13 17 18 19 5 11 2 12 19 Mean Implantations, Liveborn, and Stillborn S.D. per Litter by Group c Parental Litters Implantations 15.3 1.9 15.6 2.1 15.2 2.3 15.6 2.0 15.3 2.0 Liveborn 14.2 2.2 14.2 2.6 13.4 3.6 13.8 3.0 13.4 3.3 Stillborn 0.1 0.3 0.4 1.4 0.2 0.4 0.1 0.4 0.2 0.6 F I Litters Implantations 14.8 3.0 15.8 2.1 14.7 2.8 15.0 2.9 14.5 2.9 Liveborn 13.6 2.9 13.7 2.4 13.8 3.0 13.5 3.1 13.3 2.8 Stillborn 0.2 0.5 0.2 0.5 0.2 0.6 0.2 0.5 0.1 0.2 "Original analysis counted cycles from the day following estrous (or proestrous if diestrus followed proestrous without observation of estrous) to the day following the end of the next estrous.