AU V IS _ IO'1 3M Company Page 1 of 121 FINAL REPORT Epidemiology, 22-3W-05 Medical Department 3M Company St.

2002 SEP 25 AM 9* 29 A The Society of the Plastics Industry, Inc 1801 K Street, N.W., Suite 600K Washington, D.C. 20006 202.974.5233 / 202.293.0005 (fax) aweidman@socplas.org Allen C.

S 85 pp COLUM BUS, OHIO OFFICE TWELFTH FLOOR 21 E A S T STATE S T R E E T CO LUM BUS, OHIO 43215-4221 614-221-2838 FAX: 614-221-2007 Roberta.

R 6_ / 3 / f / RECEIVED 0PPTMCIC Telomer Research Program Clariant Report Title: 8-2 Telomer B Alcohol: Subchronic Toxicity 90-Day Oral Gavage Study in Rats Author(s): Gregory S.

PFHS 3M FLUOROCHEMICAL SUBMISSIONS February, 2002 - May 11, 2004 TOXICOLOGY, EPIDEMIOLOGY AND MEDICAL SURVEILLANCE Click on Study Title to View Report Perfluorohexane sulfonate Pharmacokinetic Study 1.

Toxicological Summary PFOS Dietary Chronic Definitive Reproductive Study: Mallard Test Substance: Perfluorooctanesulfonate (PFOS) Structure: 1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro, potassium salt.

3 FLUOROCHEMICAL SUBMISSION 2004 Click a Month back to year menu TOXICOLOGY, EPIDEMIOLOGY AND MEDICAL SURVEILLANCE April May June July November December

NORTHERN KENTUCKY OFFICE SUITE 340 1717 DIXIE HIGHWAY COVINGTON, KENTUCKY 41011-4704 606-331-2838 513-381-2838 FAX: 513-381-6613 DAYTON, OHIO OFFICE SUITE 900 110 NORTH MAIN STREET DAYTON, OHIO 45402-1786 937-228-2838 FAX: 937-228-2816 R o bert A.

TestResults AR226-2125 file:///C|/WINDOWS/TEMP/Monomers C-8 2-26-73 to n 8-5-81 9 pages.htm J TestResults Sam ple Dat Range C oncentration Range A ctio n Level Industrial Hygiene 2/26/73 100% 8/5/81 Sample D t Sample # D uration Type Employe Name Pers BTO : 08 TEFLON LOC : 016 MONOMER ANALYZER COMPUTER ROOM 11/15/79 61389 z 11/26/79 61390 z 11/29/79 61391 z C hem ical Cone U nit Percent C-8 0.0006 PPM 0.0% 0 8 0.0003 PPM 0.0% 0 8 0.0004 PPM 0.0% BTO : 08 TEFLON zLOC : 023 TRAINING FACILITY (OLD PROD C.C.) 3/3/81 54817 3/3/81 54818 'z 3/16/81 54819 3/17/81 54820 3/18/81 54821 3/18/81 54822 3/19/81 54823 3/19/81 54B24 z z 2 z z z 3/27/81 54825 z lo f 16 BTO : 08 TEFLON LO C : 701 FINE POWDER DRYER-EAST SIDE #2 0 8 0.0004 PPM 0.0% 0 8 0.0005 PPM 0.0% 0-8 0.0002 PPM 0.0% 0 8 0.0008 PPM 0.0% C-8 0.0002 PPM 0.0% 0 8 <0.0001 PPM o.0% 0 8 0.0003 PPM 0.0% o.b%0 8 0.0004 PPM 0 8 <0.0001 PPM 0,0% 8/28/2001 4:41 PM E ID 129508 AJP007141 TestRssults Me:///C|/WINDOWS/TEMP/Monomers C-8 2-26-73 thru 8-5-81 9 pages,htra 2/26/73 62670 9/3/74 62671 2/3/77 62672 2/16/78 62673 2/12/79 62674 12/13/79 62675 12/31/80 62676 8/5/81 62677 8/5/81 82678 Z Z Z Z Z Z Z Z Z C-8 C-8 C-8 C-B C-8 C-8 C-8 C-8 C-8 <0.1 PPM 0.0% <0.1 PPM 0.0% <0.1 PPM 0.0% <0,1 PPM 0.0% <0.1 PPM 0.0% <0.0001 PPM 0.0% 0.0073 PPM 0.0% 0,0091 PPM 0.0% 0.0005 PPM 0.0% BTO: LOC : 08 TEFLON 702 FINE POWDER DRYER CONTROL ROOM (ALSO SEE TTF031 2/26/73 57136 Z C-8 9/3/74 57137 Z C-8 2/3/77 57138 Z C-8 Tuesday, August 28,2001 3:18:48 PM <0.1 PPM 0.0% <0.1 PPM 0.0% <0.1 PPM 0.0% Page 1 of 9 2 of 16 AJP0O7142 Sample Dt Sam ple # D uration 2/16/78 57139 Type Employee Name Z 2/12/79 57140 Z 11/28779 57141 z Pers Chemical C-8 C-8 C-8 Cone U nit Percent <0.1 PPM <0.1 PPM 0.0002 PPM 0.0% 0.0% 0.0% 8/28/2001 4:41 PM E ID 12 95 09 TestResults 1 11/29/79 57142 7/9/80 57143 7/14/80 57144 7/16/80 57146 8/28/80 57146 6/8/81 67147 6/13/81 57148 7/21/81 57149 7/23/81 57150 file-7//C|AVTNDOWS/TEMP/Monomers C-8 2-26-73 thru 8-5-819 pages&tm Z 0 8 0.0005 PPM 0.0% Z 0 4 0,0009 PPM 0.0% Z C-8 0.0022 PPM 0.0% Z C-8 0.0001 PPM 0.0% Z C-8 <0,0001 PPM 0.0% Z C-8 0.0004 PPM 0.0% Z C-8 0.0004 PPM 0.0% Z C-8 0.0002 PPM 0.0% Z C-8 0.0003 PPM 0.0% BTO: LOG: 08 703 TEFLON FINE POW DER PACKOUT ROOM 2/3/77 49590 Z 2/16/78 49591 Z 2/12/79 49592 Z 11/12/79 49593 Z 11/14/79 49594 Z 12/31/80 49595 Z 6/16/81 49596 Z BTO: LO G : 08 704 TEFLON A/S - FINE POWDER C-8 W EIGH HOOD 2/3/77 51169 Z 2/16/78 51170 Z 2/127/9 51171 Z C-8 <0.1 PPM 0.0% 0 4 <0.1 PPM 0.0% C 4 <0.1 PPM 0.0% C-8 0.0003 PPM 0.0% C-8 0.0001 PPM 0.0% C-8 <0.0001 PPM 0.0% C 4 <0.0001 PPM 0.0% C 4 <0.1 PPM 0.0% C 4 <0.1 PPM 0.0% C-8 <0.1 PPM 0.0% AJP007143 f 3 of 16 8/28/20014:41 PM E ID 129510 TestResults 12/3/79 61172 12/31/80 51173 file^/C|/WINDOWS/TEMP/Monomets C-8 2-26*73 thru 8-5-81 9 pages.htm Z C-B 0.0008 PPM 0.0% Z 0 8 0.0004 PPM 0.0% BTO : 08 TEFLON LOC : 705 DISPERSION PACK OUT AREA 1/16/80 60378 Z 1/17/80 60370 Z 3/31/80 60380 6/16/81 60381 Z z OS 0,0017 PPM 0.0% C-8 0,0002 PPM 0.0% C-8 <0.0001 PPM 0.0% C-8 0.0002 PPM 0.0% Tuesday, August 28,2001 3:18:48 PM Page 2 o f 0 ) 4 of 16 Sample Dt Sam ple # D uration Type Employee Name BTO ; 08 TEFLON LO C: 706 FINE POWDER DRYER #3 10/5/79 48575 Z 10/15/79' 48576 Z 10/17/79 48577 z 11/14/79 48578 z 12/13/79 48579 s 1/30/80 48580 2 4/29/80 48581 Z Pera Chemical Cono U nit Percent C-8 0.002 PPM 0.0% C 8 Q.0002 PPM 0.0% C-8 0.0044 PPM 0.0% C-B 0.004 PPM 0.0% C-B <0.0001 PPM 0,0% C-8 0.0065 PPM 0.0% C-8 0.029 PPM AJP007144 8/28/2001 ra E ID 129511 ' TestR'esults 4/29/80 46582 7/14/80 48583 7m m 48584 7/23/80 48585 7/29/B0 48586 7/29/80 48587 6/5/81 48588 6/5/81 48589 6/9/81 48590 6/9/81 48591 6/13/81 48592 file:///C|AVINDOWS/TEMP/Monomers C-8 2-26*73 thru 8-5-819 pages.htm 0-0% Z C-8 0.005 PPM 0.0% z C-8 0.0095 PPM 0.0% z C-8 0.0039 PPM 0.0% z C-8 0.0009 PPM 0.0% z C-8 0.0055 PPM 0.0% z C-8 0.0051 PPM 0.0% z C-8 0.0081 PPM 0.0% z C-8 0.0043 PPM 0.0% z 0 8 0.0015 PPM 0.0% z 0 8 0.0016 PPM 0.0% z C-8 0.0015 PPM 0.0% BTO : LOG : 08 707 TEFLON FINE POW DER DRYER #2 10/15/79 60137 2 10/17/79 60138 z 12/11/79 60139 s 12/11/79 60140 2 4/17/80 60141 z 4/17/80 60142 z 6/3/81 60143 z 6/3/81 60144 z 6/13/81 60145 z 0 8 0.0003 PPM 0.0% 0 8 0.0047 PPM 0,0% 0 8 0.0038 PPM 0,0% 0 8 0.0038 PPM 0.0% 0 8 0.0051 PPM 0.0% C-8 0,0035 PPM 0,0% 0 8 0.0946 PPM 0.0% 0 8 0.0061 PPM 0.0% 0 8 0.0014 PPM 0.0% A P 0 0 7 1 4 5 I 5 of 16 8/28/2001 4:41 PM E ID 129512 "TestR'esults 7/21/B1 80148 7/21/81 60147 7/22/01 60148 7/22/81 60149 file:///C|AVrNDOWS/TEMP/Monomers C-8 2-26-73 thru 8-5-81 9 pages.htm Z 0 8 0.0358 PPM 0.0% Z 0 8 0.0056 PPM 0.0% Z 0 8 0.0445 PPM 0.0% z 0 8 0.0058 PPM 0.0% BTO : 08 TEFLON LOC : 708 P/S - FINE POWDER PACKOUT (0BPJ) 10/17/79 49585 z Tuesday, August 28,2001 3:18:48 PM 0 8 <0.0001 PPM 0.0% Sample Dt Sample # D uration Type Employee Name 12/11/79 49586 Z 1/ 16/ao 49587 'z Pete Chemical C-8 C-8 Cone U nit Percent 0.0032 PPM 0.0006 PPM 0.0% 0.0% BTO : OB TEFLON LOC : 709 DRYER FLOATATION TANK 12/11/79 48867 z 0 8 0.0012 PPM 0.0% BTO : 08 TEFLON LOC : 710 FP&D AUTOCLAVE CONTROL ROOM 11/13/79 62583 z 11/15/79 62584 z 12/10/79 62585 z 12/13/79 62586 z 0 8 0.0006 PPM 0.0% 0 8 0.0007 PPM 0.0% 0 8 0.0004 PPM 0,0% 0 8 0.0001 PPM 0-0% AJP007146 6 of-16 8/28/20014:41 PM E ID 129513 TestKesults 1/25/80 62587 2/11/80 62688 2/26/80 62589 6/26/80 62590 7/14/80 62591 7/16/80 62592 7/31/80 62593 7/31/80 62594 8/4/80 62595 8/25/80 62596 1/8/81 62597 3/5/81 62598 6/13/81 62599 7/23/81 62600 file7//C|/WINDOWS/TEMP/MoEomets C-8 2-26-73 thm 8-5-819 pagesitm Z C-8 0,0012 PPM 0.0% Z C-8 0.0008 PPM 0,0% z C-8 0.0004 PPM 0.0% z 0 8 0.001 PPM 0.0% z 0 8 0.0024 PPM 0,0% z 0 8 <0.0001 PPM 0.0% z 0 8 0.0005 PPM 0.0% z 0 8 0.0009 PPM 0.0% z 0 8 0.0026 PPM 0.0% z C-8 .

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AR226-2173 _?

Stephen W C onstable 09/08/2000 11:02 AM To: W illiam G 0 'Brien/AE/DuPont@DuPont cc: Ta-Wei Fu/CL/DuPont@DuPont Subject: analytical for C8 I met willi Ta-Wei (his morning and he mentioned dial you were searching for a method to analyze CK.

M ia-7/g Ciba Specialty Chemicals Corporation USA Regu^tory Services S O-' RECEIVED 05 JUN n AHffl-* } 7 SANITIZED L Ciba DIIII IIIIIMilIII IIIIII 8 EHQ - O ) 5 6 June 9, 2005 ^ 9 - otfor - /*osr ederal Express Confidential US Environmental Protection Agency 1 OPPT Document Control Office Mail Code 7407M Attention: Section 8(e) Submission EPA East Building, Room 6428 Company Sanitized 1201 Constitution Avenue NW Washington, DC 20460-0001 Subject: TSCA 8 (el Notice - Cyclohexene-carboxylic acid, ffdi-propenylaminol carbonyll- sodium salt, reaction products with pentafluoroiodoethanetetrafluoroethvlene telomer, ammonium salts Dear Section 8(e) Coordinator: This letter contains Confidential Business Information (CBI).

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Katherine E.