April 14, 1953 AIK MAIL Mr.

M arch 7, 1956 M r.

J une 26, 1957 Dr* F re d e ric k L Hoffman Cancer Hesearch Laboratory 135 South 3 6 th S tr e e t P h ila d e lp h ia , Pa* Dear D octor Hoffman 1 Thanks f o r your fu r th e r l e t t e r o f June 17 th I th in k you are q u ite r ig h t in b e lie v in g th a t p ressu re ought to be brought to bear on th e managements o f le a d p la n ts w ith s e r io u s lea d hazards# However th e type o f p r e ssu re which m ight be e x p e c te d to y i e l d r e s u l t s i s t o 3ctne degree som ething o f a m a tte r o f c o n je c tu r e # I n c i d e n t a l l y I am not speaking of sm all p lan ts belonging to sm all producers# R ather th e p la n t s which I have in mind are p la n ts owned and managed b y r a th e r la r g e o r g a n is a tio n s * I t would be somewhat d i f f i c u l t f o r me to i n i t i a t e any m easures f o r compelling changes in c e r ta in of the p lan ts which I have seen * Over a p e r io d of s e v e r a l y e a r s , we have made changes in a number o f le a d p la n ts and I have d e lib e r a t e ly s e l e c t e d what I th ou gh t would b e among th e w o rst lea d hazards to be found because I wanted to see th e maximal lim its of lead exposure, and the evidence of such exposure cn le a d e x c r e t io n and on c l i n i c a l sym ptom atology* My e n tr e e in t o th e s e p la n ts was p rovid ed through an under s ta n d in g t h a t I sh ou ld b e p e r m itte d t o make o b s e r v a tio n s fo r s c i e n t i f i c p u rp oses, and not f o r p u b lic a tio n in which u se was made o f names of o r g a n iz a tio n s * I f you w i l l r e f e r to cue o f my a r t i c l e s which appeared in the September 1933 number o f th e Jou rn al o f I n d u s tr ia l Hygiene# you w i l l fin d r e fe r e n c e to an unnamed w hite le a d p la n t and to another unnamed sto r a g e b a tte r y p la n t# I f you r e f e r to i t , you s i l l s e e th a t oases of p o iso n in g wore d e f in it e ly rep o rted to have occu rred among th e p la n t p o p u la tio n in which m ost o f th e men were e x c r e t in g e x c e e d in g ly h ig h q u a n t it ie s o f lea d # The le a d c o n te n t o f th e tw e n ty -fo u r hour f e c a l sam ple was as h igh as 0 .2 1 m illig ra m s in c e r ta in in s t a n c e s , w ith a number of r e s u lt s over 10 m illigram s* Such r e s u l t s , in our e x p e r ie n c e , correspond to atmospherio p o llu tio n s w ith lea d dust of the order of magnitude o f 10 to 40 m illigram s per 10 c u b ic m eters o f a i r .

July 20, 1959 Dr.

January 30, 1958 D r.

October 1, 1959 Mr.

July 22, 1959 AIR MAIL L.E, Curtis, M.D.

Ml IE T A IL IPIR O G IP *= PUBLISHED BY THE AMERICAN SOCIETY FOR Ml 701 EUCLID AVENUE CLEVELAND, OHIO November 50, 1958 Dr.

November all- 1957 : F*'Al, Wentworth*f *'?

COPY March 10, 1955 The Jo u rn al of the American Medical A ssociation 535 Hoijth Dearborn S tre e t Chicago 10, I llin o is TO-'THE' F.DIT0H: ; Hie January 22 issu e of th e Jo u rn al contains a re p o rt authorized -by the Council on I n d u s tr ia l Health and the Council on Pharmacy and /Chem istry, e n title d "Misuse of .dathamil Ca le ium-Di s odium f o r Prophylaxis o f Lead Poisoning."

ETHYL CORPORATION APPROVAL OF TECHNICAL PUBLICATION \ To: Members of the Technical Publications Committee E.

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December 1, 1950 Air Mail Mr.

July 24, 1958 Confidential Mr.