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# AR226-2834
Material TestedT
Haskell Laboratory f
f"0"" and cn>Pany
y ior Toxicology and Industrial, Medicine
HASKELL LABORATORY REPORT NO. 162-73
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'
Material Submitted by; department,
tProcedure--* TJ-huoG t,,sii.t material ao to young adult cha m , ai* as a 8wpenion in
ACUTE_ORAL_TEST
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ma 6 rats in sin8le doses' Survi- - 0- - 0lsac(^ f ? f ^ ---- --- --------
lntra*aat^ m o t i o n y Jaterlivers were removed for
Dose
E&&S 2,250
670 450 300 200 130 60
Suspension
Mortalitv*
10 10
D - 4 d. D - 4 d.
10 D - 4 d.
J S - 14 d. 3 >> - 14 d.
'X
1 6 - 14 d. S - 15 d.
Liver Wt. J f o
-
18.83 15.27 13.91 17.46
-Summary:
-- ----- --- _
Liver Wfc_ Body Wt. x 100
-Clinic a l .Signa '> 4 t W "I
5.79 5.23 4. 81 4.95
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weight loss from l-S^ays ffJor ^
thar8y and
neal area on 3rd adaayy an^ittee-r ddnolsningdoastin2,;25w0etmgP/ekrgi.-
Nonletha1 Doses* Rnf^iinai <
above, lethargy at nhf"|e^/i U "" at ^ mB/lc8 and
dosing-;- in-i-t-i-al- w-teai-gihnt. llosss,? ^ "bVe " day of
ALD 450 mg/kg
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s' ' ' *' -*^2 >S:ssssi
N C D :dhg -52tej ^E.ril 13, 1973
e/kg *"d above produce heavy liver, i,,
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Report by: Approved by;
& ;<$<%..c.
/ Nnancy Cu. Dale Oral Toxicology Section
Company Sanitized. Does not contain TSCA CB1
Jr. Director