Document pm73BdDo4Be0y6QE05a5Mx0yd

HUlhouse Site PC. Box No 4 Thornton - Cleveleys Blackpool FY5 4QD i1 Telephone (0253) 861632Direct lin (Seer tary 861370) (0253) 861444 Switchboard 6632Extension Number Facsimile (0253) 864687 Telex 67483 Idpiast Clviys CONFIDENTIAL Dr T R Torkelson 1803 Building Dow Chemical USA Midland Michigan 48640 USA Your ref Our ref BB/BGS Imperial Chemical Industries PLC MEDICAL DEPARTMENT 73 (/) O co o GO o Date 3 March 1986 Dear Ted ANGIOSARCOMA OF THE LIVER I enclose a copy of the Register updated to 1 January 1986. t^gotirewiwfe in-nnf wirim- lours sincerely v B BENNETT M.A MaB* ^BaCha fB&0* D.Obst.R.C.O.G. D.I.H.,M.F.0.M. enc {a Crv*!***^ M* Ovictsw* nWi"o lmn*nof AfWhantr 1 nnVw CWlP IP nwnouse Site PQ Box No 4 Thornton - Cl veleys Blackpool FY5 4QD Telephone (0253) 861632Direct line (S cr tary *861370) (0253) 861444 Switchboard 6632Extension Number Facsimile (0253) 864687 Telex 67483 Idplast Clvlys CONFIDENTIAL To all recipients of ASL Register Imperial Chemical Industries PLC MEDICAL DEPARTMENT Your ref Our ref BB/BGS Date 6 March 1986 Dear Colleague REGISTER OF CASES OF ANGIOSARCOMA OF THE LIVER DUE TO EXPOSURE TO VINYL CHLORIDE - REVIEW DATE 1 JANUARY 1986 I regret that due to a typing error an amendment is needed in Table 1 . (Page 30) of the Register recently sent to you. Against the year 1980 would you please alter the figure 0 to read 10. The total, of course, remains correct. With apologies Yours sincerely R&S 103081 B BENNETT M.A. M.B. ,B.Ch. ,B*a.O. D.Obst.R.C.O.G. D.I.H.,M.F.O.M. UOT ANGIOSARCEMA CASES HHt/43. - 49. ABBESS rTpmr^TTiTJ CF REGISTER ADAMS Dr A Boss Air Products, Allentown, Pa, USA BAJSHAW Dr I HM Nar& Hydro, Newton Aycliffe, tK BAND Dr P R Cancer Control Agency of British Golunbia, Vancouver, Canada BARNES Jnr W C Monsanto, St Louis, Missouri, USA BARR Dr J T Air Products, Allentown, Pa, USA BARRAT Dr G AECRP, Coamentry, France BAXTER Dr Peter EMAS, London, IK BEADPRE M Garemnent of Quebec Cancer Registry, Canada BENECH Dr M Naphtachimie, Lavera, France BENNETT Dr B ICI HLUhouse, IK BOOmt Dr P Inst of Occupational Health, Milan University, Italy BESOT: Dr Dynanlt Nobel, Trolsdcrf, Germany BISHCP Dr C EMAS, Bootle, IK BCRRELH F E Georgia Gulf, Delaware City, USA BOXER R W Formosa Plastics, Delaware City, USA BURGESS Mr David Id Anerlcas, Wilmington, Delaware USA EYKEN Dr David Kaoanord, Stockholm, Swedsi CARTER Dr J T EMAS, London, IK CELIA Mr C Enlchem Palimeri, Milan, Italy CHANCE Mr M Id Runcorn, IK CLAUS Mr P G ARC, Brussels, Belgian CLAXTON Mr H Norsk. Hydro, Newton Aycliffe, IK CONTASSOT Dr J Chine Chimie, Saint-Fons, France DAVIES Mr J G Id, Everberg, Belgiun (2) DE SLOWER Dr Solvay & Cie, Brussels, Belgium EE VOS Mr A J Id Everberg, Belgian DIETZ Dr H W B F Goodrich, Akron, Ohio, USA DOLL Sir Richard Imperial Research Fund, Oxford University, IK DCMBROWSKI S L Dow Chemical, Midland, Michigan, USA DUPCNT Mr G ARE, Brussels, Belgium EMiltUR Mr H VKE, Frankfurt, Germany ERNST Dr W Berufsgenoeamsdiaft der Cheidsdten Indistrles, Nurhberg, Germany FALK, Dr H Oiroolc Diseases Dlv, US Dept of Health & Hunan Services, Atlanta, USA EERGUSQN Dr D M Id Anerlcas, Wilmington, Delaware, USA KJRMAN Dr D Imperial Cancer Research Fund, Oxford University, IK ERASE R W DiversiTeeh General, Akron, Ohio, USA IRIEDEL Dr H P Berufsgenossenschaft da Chemlschen Industries, Heidelberg, Germany GOOTRG Prof L Duke Univ Medical Center, Durham, North Carolina, USA GOSZTCNYI Jnr Dr R E Teaneco Chsuicals, Piscatawny. New Jersey, USA G0ITE91AN R T The Vinyl Institute, New York, USA HARRIS Dr WD IMroyal Inc, MlddLebury, Connecticut, USA HILL Dr G B Alberta Cancer Board, Edmonton, Canada HIIZMANDr D W Diamond Shamrock Corp, Dallas, Texas, USA SHEERER Dr R K BF Goodrich, Cleveland, Ohio, USA HXGSCN Mr J EMAS, Bootle, IK H3GG Dr W A Imperial Oil Ltd, Sarnia, Ontario, Canada HOWARD Dr J K University of Otago School of Medicine, Wellington, New Zealaxi HUMEBRY Dr N F Id Australia, Melbourne, Australia JADVEKT Mr J Chloe Chimie, Paris, France JERVIS Mr H R Id Millhank, London IK KAKRH Dr Bruce Dupont, Wilmington, Delaware USA KREUGER Dr R A BF Goodrich, Akron, Chio, USA LAIOINE Dr J P Solvay, Brussels, Belgian LAtEAM Dr John Dow Chemical Europe, Horgen, Switzerland LAWRENCE Mr J SPI, New York, USA LAWRENCE-JCNES Sir Christopher, Chief Medical Officer, Id, London IK LEE Dr F I Victoria Hospital, Blackpool, Lancs, IK LELBACH Prof IK University of Beam, West Germany IEVEQDE Dr G CDF Chimie, AZF, Bully-lee-Mlnes, France LEVISCN Dr D A St Bartholomew's Hospital, London, UR LEWIS Dr P Chsnical Industries Association, London, UR IQLIVIER Mr Solvay, Brussels, Belgium LDSSAXO Dr J Atochsn, France 03 IIP </> o 03 O 00 to -2- WEX/ASL - Ai>L_ADCBESS,2 R&S 103083 MftTTUam Dr J M Medizinsche Abteilung, Luzem, Switzerland MSUKHRA Anna Statistics Canada, Ottawa MSL3CNX Prof C Institute di Oncologla, Bologna, Italy MAHRE Prof Lo Medil-Anic-S, Milan, Italy MAHHJSSI Dr R Montedison, Milan, Italy MKDIZrCN D Norsk Hydro, Newton Aycliffe, IK M3KKA Mr Neste Oy, Espoo, Finland MXUESAM) Dr R IARC, Lyons, France tom Dr AA Duperlal SAIC, Buenos Aires, Argentina MINN Dr A Moatanto, Brussels, Belgiun MINE MJUTCN Dr M Wo ftodano, Madrid, Spain MacSWEEN Prof BNM Western Infirmary, Glasgow, Scotland NAK/MJRA S Japanese WC Association, Tokyo O'SULLIVAN Dr JJ IQ Runcorn, IK OLSON H G VC Safety Association, Louisiana, USA OMEN Dr R Trades TMon Congress, London, TK patttf Dr g M IQ Central Medical Group, Alderley Park, IK PAGLXALDNGA Dr S Montedison, MLlan, Italy POPPER Dr Hm Mount Sinai Medical Center, New York, USA POSSBERG Dr J Wadcer-Chemie, Munich, Germany HJECH Dr A M Atochan, Brigand, France HJRDHAM Dr J rnnnH-tan Centre for Occupational Health & Safety, Hamilton, Canada RAMBAIT Dr J RP Recherches, Antcny, France RANGES F Norsk Hydro, Fersgnmn, Norway RICHARD Dr P Rhone Poulenc, Roussillon, France ROBSON Mrs D Saskatchewan Cancer Fotmdarlop, Regina, Canada RODRIGUES Dr MJF IQ, Sao Paulo, Brazil ROUSH Dr G Monsanto, St Louis, Missouri, USA RDIY Dr J Atochem, St Auhsn, France SALS Dr J NXOSH, Cincinnati, USA SARAOQ Dr R IARC, Lyons, France SOEFEERS Dr M L DS1/C9MD, Geleen, Holland SCHQPBRDrH University of Manitoba, Winnipeg, Canada SEROIWE Dr D Diamond Shanroek, Dallas, USA SHAH Dr Has (MA, Washington DC, USA STGRIST Dr J Shell Oriole, Berre L'Etang, France sum Dr E Division of BwimiuMtal Health, World Health Organisation, Geneva, Switzerland Sffim Dr P M Llandough Hospital, Penarth, UR SPIKEAS Dr R NCX/NIH, Bethesda, Marylanl, USA STAEKKD Dr J Scmeraet, UK SIAMECKER Mr BASF, Ludwlgehafen, Getmany TAMBURBD Prof CH University of Louisville, USA TER HAAR Dr Gary Ethyl Corporation, Baton Rouge, Louisiana, USA THWEESCH Dr B Qmmische Werke Hols, Kreis ReckllnghaiBen, Germany THMHAnr.T Dr GUI-- Mecill University, Montreal, Canada thtbss prof Dr AM BASF, Ludvigshhafen, Germany IHIIS-EVEtBCN Dr E Norsk Hydro, Porsgrum, Nanny THMPSDN Dr D H Cancer Treatment & Research Foundation, Halifax, Nova Scoria, Canada TCRDQR Dr W Shell, An Da Haag, Holland VAN HER MEEHE Dr H J AEQ, Sasolburg, South Africa WALLACE J R Eseo, Sarnia, Ontario, Canada WALEEMAIE H BF Goodrich, Cleveland, Ohio, Uaa WEJDLDE S 0 Kananord, Stockholm, Sweda WHEELER Dr D J IQ Hillhouse, IK WHEELERRN Union Carbide, South Charleston, USA WHISTONDr J IQ Htllhouse, IK WHnE K H Duperlal, Buenos Aires, Argentina WUHEKI 0 Electrochemical Industries, Acre, Israel WIUIAhC Dr EMJ BP Chemicals, Penarth, IK WHSCN Prof R Harvard University, Cambridge, Massachusetts, USA WRIGHT Dr A P IQ Wiltcn, IK J IQ Everherg, From Dr B Bennett, Medical Department, Tmpneinl Chemical Industries Pic Hillhouse Site, FO Bax 4, Thornton-Qeveleys, Blackpool FY5 4QP, UK. Fphnvrr-tr 1 CONFIDENTIAL REGISTER OF CASES OF ANGIOSARCOMA OF THE LIVER DOE TO EXPOSURE TO VINYL CHLORIDE - REVIEW DATE 1 JANUARY 1986 PREFACE t Acknowledgments, significant changes and comments 1. The new cases in the Register are the following : France Germany UK 18 23, 24, 29, 26, 2? 11, 12 2. Th re are amendments from the previous Register against the following cases: Germany 21, 22 US 36, 38 3. I would like to thank Dr De Sloover, Dr D M J Williams and Dr Friedel for informing me of new cases. 4. For the case corrections I would like to thank Dr Friedel, Hr J T Barr and Mr R W Frase. 3* For othercorrections and information, thanks to Dr D Forman, Mr J T Barr, Hr T HSutherland and Mr N F Humphry. 6. I should be verygrateful ifall recipients of theRegister could continue to keep me fullyinformed f any new cas a, or, if they should hear of other Companies who have acquired a case of ASL, it would be much appreciat d if I could be notified by the appropriate person. It is extremely helpful if new information is supplied in tabulated form, using the headings in the Register as far as possible. 7. I would like to thank the many people who have suggested research topics, and should be grateful if I could be kept up to date. 8. I shall be happy to supply to any recipient of the Register a copy of the Paper "Exposure to Vinyl Chloride and Angiosarcoma of the Liver: a report of the Register of cases" by Dr David Forman, myself, Dr John Staff rd and Sir Richard Doll, published in the British Journal of Industrial Medicine, November 1983 (42: 790-733) Dr Brian Bennett Medical Department Imperial Chemical Industries pic Hillhous Site P 0 Box 4 Thornton-Cleveleys Blackpool FY9 4QD England F bruary 1986 *80801. S9U S80C01 S9U IMPERIAL CHEMICAL INDUSTRIES PLC WPX/ASL_2 - LANGI0CASES.4 ' Index LIVER ANGIOSARCOMA CASES (REVIEW DATE - l JANUARY 1986) Table Sequence Belgium Canada Czechoslovakia France Germany Italy Japan Norway Sweden UK USA Yugoslavia Incidence of Casea per annum (Table 1) Page 1 2-3 4 5-8 9-14 15 16 17 18 19-21 22-28 29 30 ASL Case Numbers by year of Death (Table 6) ASL Case Numbers by year of first exposure (Table 7) Western Europe PVC Producers - Start-up Dates vs ASL Cases (Table 8) USA PVC Producers - Start-up Dates vs ASL Cases (Table 9) Canadian PVC Producers - Start-up Dates vs ASL Cases (Table 10) East European PVC Producers - Start-up Dates vs ASL Cases (Table 11) Japanese PVC Producers - Start-up Dates vs ASL Cases (Table 12) South & Central American PVC Producers - Start-Up Dates (Table 13) Australasian PVC Producers - Start-up Dates (Table 14) Page 42 43 44 45+46 47 48 49 50 51 Distribution of Casea by Country (Table 2) 31 Pattern of Cases by Factory (Table 3) 32 Latency Periods (Table 4A) 33 Distribution of Latency Periods (Table 4B-4H) 34-40 Annual Geographical Incidence (Table 5) 41 4 I (EELCIUH 'V IHPEK^AL CHEMICAL IHDUSTtlES PLC LIVE* An* 1 nearcom CAM* - (lavlau Data I I January 1304) IIFS/ASL_2 - LANC10CA4ES,A 1 i 3 4 3A 7 4 * to II 11 13 14 13 14 COUNTtY AND INIIMCI HO HAH! Oft INITIALS MTI or ftlftTH cghtahy PACTOET msx vc eiposur* DATS or DIAGNOSIS ACI AT DIACHOS13 iiau or urosui* TO DIAGNOSIS TCAftS or Exrosuftft DATE OF DEATH KISTOUhGICAJ. COHf 1ftNATION ESTIMATED mosuaa LEVEL OCCUPATION OWE* CAEEHE 1CIILICIITS OTNUt C0HHCNT3 . IELC1IM 01 11 1 11.01.13 ftolvay 00.07.S3 00.03. 74 43 ia 1 i l 02 3ft 1* 03 AO ftolvey Janappa 20 01 41 00.10.73 33 17 17 13.04.74 Tee Nl|b Aatoclaaaar Drlllor la NepetJc tuti 1A yra fooadry In Oct 1324 1350-1963 (1 yra) wara cornel, ftxpaatd to Polyuarbar ParMr 200 ppa 3 yra 03 yra) tetlrad rob 1373 tor ft hn Hark In |laaa Roaplulliii ft 4iy Ini. 4 clwal- Mar 1376 lot cal InJuatry cartaint? Cooptoto Jor Clinical ant 500 pf coraor detail* 1b. A to So3 aro glean lo A papar by autoclaves uirfur Nublat at at la Arch. Saif. aapoaai t 30-100 ppa Ha4. Sac., Hr*. Hal. 4 bra par Trav. M*. 4r.i IS.1 La*. 1377 pa*aa autoclavaa ii/i-iiH 401-411 saposad to 50-200 pf lo auto clave roaa Tnrnar- ri 1373- 30 PH" EETIBEO 1 rab 1373 3 13 10 03 Taa 03.41-03. 43 01.47 -10.71 100 ,tm Ill/lay OA.43-11. 44 * 100 PI* Autaclaanar flreoea elace 3 yra 3 atba 10 71. Oyaiatar 3 yra 3atha. lat algo July 73t Thoracic paU 07* 73 NapatJc taata altered IO73a roaltlee achog raphy 11.73. Ilapateccooy 02.30a Cheaotherapy, laioraitlon glean to letter 12 Noe 1334 fro* Or De ftlooeec. 980001- S9U zsoeoi syu '<! * CANADA IHKIML CHEMICAL 1H0USTSIIS tic LIVER Aailaurcoai Cihi * (ItvUv lta(i l Jea 1RBA) All dltn uaa M lyitM MT - MONTH - WAS Wl/AELJ - LANQ10CAUS.7 1 1 S1 S0 7 a t 10 11 n 11 11 IS IS CMHtpiT AND irtUNCt MO NAME 00 INITIALS OATS or BIRTH CAMARA 01 IS.11.IS COMMIT FACTORY FIRST VC UV03URR PATH or 01AGNOSIA AOS AT OIACNOSia vaias or UFOSliai TO DIAGNOSIS TEARS OV OATH or EXPOSURE DEATH niSTOLOCICAL CONriaHATION aatiHATU uroauta LIVBL OCCUPATION OTHER CABKEt HICHLICUIrE OTHEE . COHHEim SHAUII ICON 1M1 ttss 11 11 n Ol.OS.SS III Reactor cliMr Oparator Sookai polyaatlaatloa 01 00.01.11 1M1 ItST 11 11 ii 11.11.S7 III Halataaaoca, Oparator alllwrllfct, rifiimu UorfcaA ovartlaa Saefcar 0) io.oa.it 0*11 1101 11 11 10 11.01.01 III Operator, loriHt Hoital ovartlaa ttoaraaokar M 0S.01.lt mi IM7 la 11 11 ii.oi.oa III Saactor claanar foraoao. ator coollap unit Mortal ovartlaa Saakar OS 07.0S.il mi IMS ST 11 OS os.o7.oa Taa Reactor cleaner Valor cooling Mortal unit ovartlaa Saakar 04 IS.ll.lt 1*17 mi SI 11 11 10.01.71 Taa cleaner Helateoeace, Millwright IfarkaJ ovartlaa Sookai * 07 0t.ll.lt mo mi SI 10 IS ii.ii.n 1*0 Reactor clamor Hachine ebop operator o*4 poly aait Uotkal ovartlaa Saoluir 00 ll.0S.10 mi mi SI 11 OS n.oo.n III claaoar Halotaoaoca In pleat oaclilna aNop 25 yrel S*olcr 0t It.07.11 mo mi SI IS 10 01.0t.71 Taa Furaaca op, plpaflttat aatotaaaoca Uarkad ovartlaa faokar Piftr by Dr t KLORHE An Anulii A'AmImIi fttholotlqM farlc, IB7B Vo I 2) Ha 2 pplOS-114 dfefai tkll UBl hoi Loth a bafitoaa and ASL etnulteneoualy r>t* 3 CANADA Ifcaat 3 WFIEIAL CHEMICAL INDUSTRIES rLC LIVER Aatloaarcoaa Caaaa - (Inlaa Dalai I Jaa Itlt) OAT - BOOTH - HU Al i Jataa ua Ik lyata* WM/AL_l - LANCIOCASTS,* 1 1 3 4 3( 3 3 10 11 n 13 14 IS 14 COUNTS! AW befIeence HO KAMI oa 1H1TUU BATS or hath COHFAW FACTOR! HAST VC urosw* BATA or DIAGNOSIS ACE AT DIAGNOSIS TEARS OF EIFOSUEE TO DIAGNOSIS TEARS OF EirOSUEE DATS or DSATH HISTOLOGICAL COHntHATIOH SITUATED EIFOSUEE LEVEL 0CCUMT10M OTHER CAETEE HICHLIGHTS OTHAA COMMENTS CANADA 10 U.0S.1S 1*53 1334 41 33 14 00.04.33 1 laaetor claaaar furuci op, ulntMUM( Pck*|lQ| Ea-aaotar 880E01 SVU 680901 STU Fata 4 CZECHOSLOVAKIA interul chemical inwniu nc Lima ln|laMrco Caaa a - (lavlw Data) I Jaa H) Ur/ASL_1 - LAMGIOCAHR,* 1 1 i 4 14 7 a 10 it 11 11 14 ii It COUNTRY AND hams cm PATS or REFEREHCK INITIALS NISTU NO OOHFANY FIRST VC DATS or ACS AT YEARS Of TBARS Of PATS or HISTOLOGICAL IT1HATBO FACTORY KirasUR1 DIAGNOSIS DIACNOSIS EETOSIfRE to uroaima DEATH CONFIRMATION REFORM! OOCOF4TION DIAONOOU UVEL OTHER C4REU HIGIILICNTa OTUUL OWHENTt CZECHOBIOVAKIA 01 1A.0A.1* Rtata Ca Mavahy 01.07.17 14.11.71 41 It it 14.11.71 Taa Au toelava Claanar use 1 attar of 1-4-tl al*la( Eatalla ftM ftol A Davit al Cane ra lat Fllaaa aot Oee tlaaaaaa. 01 ot.07.17 tala Ca Navaky 01,11.so 17.II.M IT 14 ii lt.ll.t4 Tbr Autoclave CIiHir 1ARC lattar al 1-4-tl aava aoaauhat altatat tataa Tat tlila caaa. 1 hava accaytad tha chanfa a alaca tba tataa caaa ftna Ftol A Davit of tha Caatra oT latuattlal IlyRlana ant Occuyatloaal Dlaaaaaa. My tataa coaa originally Iron H103II. till t TEAHCE Shaat I IHTEtlAL CHEMICAL IHDUSTtlES fLC LIKE An|losiream* Cat*a " (Eaataw Dalai I Jan It) Hf*/AiL_l - HOC10CASED, 10 1 I3 4 CO0MTRY AND mHIKGR NO HAW 01 INITIAL! DATE 0* I EM A CttJMHY 3A 7 E t 10 It 11 13 It rAcroET rim vc ixrosuii om or DIAGNOSIS ACE AT DIACHOEIE TBAEE OF BXrotWE TO DIACMDSIt TEAES Or ElMUtltt OATS or HATH HflTOUUICAL COHf IHHATHHI EET1MATE0 urosuEE LEVEL OCCUTATIOH IS OTHEE CAEEU HlCttLICttTB It OTftU CCNHlItn riAMCE 01 H IS.OA.IA IF ftOUCft- 00.01.At it. oi.tr A3 11 It it.oi.tr Til Hlfh Aatacla** iiio4 uorhat aat claaaar 1* pra Eaf. Ea*tar at al Itch. Hal. rrof. 1 30 a* 1 Ho* 73 p 171-177 oi SIN D3.Ot.ll kue 0i.07.3D 13.01.73 tl It 11 IA.OI.73 Taa Ulh 1 in aa Itallii Eaf. (HIOSH as NMUMMF origin C toauatoa at 10 yu on al Hawaii* poljnir- ptaaa* laitlon aat leal a *' 3 Ha* 1377 r * 0] HA* Dt.Ol.M ir St Iona 00.00.At 13.01.73 S3 It It lt.0t.7S Taa Hitt liljwikir VCH production Eaf. tatf at 10 |n aa It vra al Arch. Hal. autoclawa Italian MM Prof. 1 37 a* claaaar Shepherd, t Juaa 71 Conpouadlng Snvynr, Haion p 331-333 3 rra 0A HQ* 37.01.IT rcur IrlgaotN It.10.A3 lt.01.7t At It It 0A.01.7i Taa Hitt Honour production Mrkir ft yri TVC filtration It yra OS 1 2*.01.31 PC1IK Ar tgnoud It.0l.t3 11.03.7t 31 11 II 13.OS.7t Taa Hlfh Polywrkar 11 rra 1 JTharacotaajr Eaf. f Cautara 3th Tab lt7t at al Taoala* coata1 taa haapltaua annloaarcoaa 10 Baptaahra l)Sclat Itrapliy Hit fount AEL Travlaualp hat l)Haaaorrba(a ban* (run ASL an* loaarcoau AlEllht Atao Hapatactaap TilIchouahl at al ta Hawaii rraaaa Hat leal 1 06060 V SYU L60C0J. S'?a v**a * nua llmt I IMmilAi. CMSHICAL INMWntU PLC LIVC* 1d|Iouicou Caeca - (liflw Datai t Jm 14*6) m/uL_i - lamciocaki.ii , 1 11 awtrirr aho lUdUU HO SAKE Oft INITIALS DAT! OV 4 OOMTANT st i 10 11 11 IS 14 VACtlMf VIMT VC nroBuu OAT* OV DIACM0S1* 40* 4T OlAflNMl* TKAU OV IKURI TO 0UCH0S1* iiaii or iirosuti ftATt or nun BHIOUttlCAL CONVMHATtfM MTIMATU Biroau** um OCCOVATIOO IS onii* CA*U* HICHLIGHT* 14 onut* COMKHII rtAHCK ot r* U.04.14 rcu* rl|aoa* 01.01.S* ii.oa.ib 41 1* n ll.0S.14 To* Moderate (1410-1460) (NIMH 1 in (litrat lea 11.04.14) 10-11 pra polpworkar ao4 work* labt Thla aaa 4*4 40L prior ta 4*. An*. 4a Hal. rear. Julp 'll * p 44S 4 6. AOL waa toua* la 1*11 (Ira pra ba(ora AIL 0? 01* 14.04.11 v *1 lain 01.01. so Altar 4* 14 ii 01.01.14 !< 1(4 Vlaat fora- 1411-6 *4ala 01*4 of death (HIOH ao au la act lea la aaptlcaaala HI0H cowaaat) polywer- t 4ubaa Saall llrar to 00.01. It laatlo* laatoa (ouaA altar autopap 01 ft 01.04.14 Itlngf Taraua is.os.si 01.11.IS 41 IS is 10.01.11 Tai Hod*rat* 6 *ra packer 4 aatoclaa* clar 14 pra autoclave worker tta4 baaa tuoaal worker prawtoualp 04 *VI 01.10.1* sr tt Foot 10.01.4* 14.04.14 41 1* 14 IS. 11.11 III Vary *1(4 Folyeer- 10 pra la Op*rata* 4.14 1440-1444 laatloa aulpbarle , lor reaoral of Lcaear operator, acl4 (actarp, tuaour (row Bapoaura autacleeaar, atorakaapar 4 llrar aa4 1444-1414 autoclave (caaral aalatanaaca a* rate** dl*4 after aacoad ur*tcal oparatloa (er Hilo broachla1 flatala Taper bp Dr tatp at al la Archlraa 4* Haladaa Vrofuaaloaala Val 40 *o 4 ISIS pa(ca 141-1. ........... ---- rail I ruHci 1HEEEIAL CHEHIOAL IHDNSTtlES ftC Live* Inilotuetw Catai - (larian km 1 Jan 1)86) UfX/ASLJt - LAHG10CASat.il ft 1 i3 oowrfir ANO ivnmi 880 NARI Oft INITIALS DATE OP IIRTN 4 COHTAMT S4 ) f 10 u n IS 14 PACTOVY rusr vc Eirasusi OATI OF ACI AT DIACH03IS 0IAC880SIS TEAM Of EIFOSIIIE TO DIAGNOSIS HAM OF urosuu DAT! OF MATH U1ST0L00ICAL amrisHATioa ESI MATIN urosuu LEVEL OCCUPATION IS OTNEE CAIEEI HICHLIGHTS it OTHM * COHHim Franco 10 vr 14.OS.It IP t (Mi 00.11.st 10.01.10 SO HL ii.61.ii IF ft Pom 00.01.4l Tnsnr 66 11 17 11 Vi.oi.U rcof Irlfoooi 0f.dl.4f 00.OS.7f 41 16 ll If.01.11 altar Tavftia TOOT 14.04,7f 46 it U ' HJ 05-04-7* Qi loa CliUla (Eoraarly M> St Faaa fill oo.oi.ta 47 16 it 10.01.It Tu it ll.11.71 la* 17 li.0t.7f Taa 11 loor Ta* St ii.o7.si Taa Nlfth Hiih Autaclava claaoar 10 pro U eekMlcil engloeerlog Industry 1946*1156 WMIM-- polpiar laittoa ptirpoai worker mi=fi7i VCM aynthasla (SCI t tcatylaua) Earaaaa (asaat da aaltrlaa) i*7i' retired 01at at pulmonary atoll au 1 daya attar aurfary High Kutttur proAeeilen eel palyair iMtloft operator Antocliaur 2 pro s cpcle Cl garatta 1 jra, aachiftlci aaokar until Auto* 10 pro oo 1174. Ill all operator oiuuaollor In nt 1S77 dua to r. saattorp were Oaaaphasaal Coyolyaara aiwloctur* varlea*. 4 yr* Surgical 1 u tar aat loa 1S.GS.79 (right Vary Hl|h lili-iiii ii75-iiii haoatact oar) lf4S~lf7S AH tppoe of slotooeoco aat Jobe on work lutaraltt- floufeeturo aatly A oolnteeeoc e 1175-1171 In VCH Mf Proeeeo __________ 360C01 SSH 06oeoi S9U Fa| ESANCE Sheet A 1HFEBUL CHEMICAL IMMIETEIEE ELC LIVIE Anilosarcoae Cases - (tiilw Date! I Jea 1IM) WK/ASL_1 - LANGlOCASEI.ll 1 1 i 4 1t 1 t t 10 It 11 13 14 IS tt COMQBT AW smEHca MO HAHt OE INITIALS DATE M I ATM COKFANT rjeroar FIEST VC EXEOSIMtt un or duchosis ACE AT OIACNOSIS TEASE OE UroSOBE TO DIAGNOSIS YIABS Of xrosima Dm op DEATH HISTOLOGICAL C0NE1BMATI0N ESTIMATED B1EOSOEE LEVEL OCCUEATION omi cum HlOHLlCm OTttEE OOHHENIS Erases 11 Dtr 01.01.11 Chios St Eoos 01.01.11 is.ot.si 41 11 ii 411va Too Htih-10 yr Auoclavi J C Ceataaeel Alala Moderate clMr Latter of (feraarly 1 E mwfti s io iota BE1 auClav a^mur It OIH 11.01.11 Chios St Eoos 11.10.41 01.01.11 tt 41 it 01.04.01 Tss lElr-11 yra Palyosrlsat- Chlolo Motorata- loo Erocass (Eoraerly Low - 1 yra Has EE) Halatsaaaca Marker Health t Safety Aye at BatlrsS Jaa I0. Letters or I 10 IStl asS II 1 S4. 1? ua 11.01.11 Also Bt East 11.04.41 oi.o4.ai to M IS 01.04.il Isa Hl(h - Autoelava Other aaetars EstlraS Alois 11 yra Claaaar of St Fans 01.01.1* (Eorosrly 1*40-1011 Factory 1*11- J C Ceatasaot EE) 1E7S Letter of S 10 1SS1 It a 14.01.41 So Way Tassos Ot.OE.41 11.01.S4 41 11 11 11.11.04 1I.01.S4 Hlsh-11 yra Daiofilava Lav - t yra Claaaax Of,01,04 ElSht Heyetactoey 01.01.0414.OE.04 ebaaotherayy for )ofaetaataala t yartlal reataatoe. OB.04 - liver recarreace. 10.44 - luntt avolutlaa of the Slasaaa I'M* * CI1MAMT lhaat I MTKRUL CHEMICAL INMIITOUS FLC LIVE* Angloaarcoaa Ca aa - (lavlew Data] 1 Jaa 1906) HFt/ULJt - lAMCI0CAM5.lt 1 1i it COUNm AND IUUIHCK HO NAME OH INITIALS DAT* or MAIN 4 COMTAMI st 1 a 9 10 11 11 11 u TACTOtY fliST VC exposure DAT1 or PI AGNOS It AGE AT DIAGNOSIS VRAM Of xromi to oucHosia TEAKS or EXPOSURE PATH or DEATH HISTOLOGICAL COMPIKHATION K STIMATto xrosuti UVXL OCCUPATION IS OTHER CARER* NICULIGHTS RRRHANV 01 00.00.30 DjraaaU TtaMwl 01.10,St 19.09.tO 10 11 11 15.01. t9 I <HIO>H) folpaarkat It ontio COHHEKIO .. 01 00.00.11 Oyaaalt Troliiorl M.10.51 15.01.70 19 11 II lt.11.11 Taa (NIMH) fol)rMrkar 01 00.00.10 Df HMlt Ihiiitfil- 09.0t.51 00.01.11 tl 11 It 10.10.11 Taa (MIOSH) nil lag Saportad Hodtt 4ii paatlclta non folyair aaroaol caaa laatUi with VC knrUra la NIOSH lUt ol )i.3*n Tfaia of coum la atrfctljr corract Hottavar l wtadar ubaitwr till an hot bl|k aapoaur* to VCH la Ala can filling o pa rat loaf Ot 00.00.10 Vackar urf* lt.Ot.51 lt.ll.lt tt IT 11 15.ll.lt laa (MIOSH) 300*500 ppm falyworkar t 1950 waa Cllalcal hMio* Ut high tMfocaii autoclaaaar datalla la during I ft autoclaam (or 1 yt MldtUiMr MP*r hi Cohal at al Vltcluwa Arch 1 rath |9Tt 111 p 195-101 veoeoi- S6080J- STb ** 10 GIIMAIH IHPCMIAI* CnEHICAL IHDOSTHIEI MX UWI Angloeateaaa Cams - (Uvliw htai I Jaa DM) Wt/MlJ - LAHOIOCAUS.IS 1 t i 4 SA i 10 II 11 11 14 IS amn aho iiriiiHci HO HAKE OB INITIALS DAT* Of sun C0HFAH1 rACTOif nur vc tiroturn DATS or DIAGNOSIS ACt AT OIAOHOSIS mu or oirotm to BtACHOSIS viau or cxrosuti DATS or nun HISTOLOGICAL OOHriHHATIOM I IT IHATEO uroms LAVEL OCCOrtTIOH oniii CAUU HIOHLICHTS It OTUU OOtMEHTt CIUlAHf OS (HIOSH glaa aa Gaaa 01) oo.oo.it- Heechat ftuAlurt 01.04.40 10.11.11 10 11 os It.11.14 Taa (HIOSH) Ot (HIOSH glvaa aa Cam OS) 00.00.11 Lomu HaUahut It.11.41 00.00. TS 41 11 11 09.01.IS Taa SO Cheata aaya 'ckaaletry laboratarlaa la tha Tac baalot leal laaaareb Capertaa at ' (HIOSH aaya atalacant factory cbaalat which aay ba wont rVC - Ha airfact uca Shift La ailat CoaflraaA layarltl under aearpelyaerlaatlaa workera la HIOSH Hat af 11.1.1) aat 1.10. 1 don't tblak tkla la a catracl elaaalflcatloa by HIOSH. The aaa aay have beta latelved la VCH palyaerteat ton la pllat pleat at la aatn plant. 0? 00.00.1A HacUr Sur*- 1S.04.S4 11.11.IS 4* 11 11 11.11.IS Taa (noaa aaya 11) rre Haaafaetata and all walk tael auto- cltaalag 11 yta (llSA-tt) fataaaa Tech Dev yra (1941-191$) 01 oo.oo.u ByBaaIt Traledatf l*.07.W 0t.O4.lS SO 10 10 IS.11.IS Taa t folyworket 1 Fa| II CERHAMI Sheet I IMPERIAL CHEMICAL INDUSTRIES FLC LIVE! Aagtoaarcuoa Caaaa - (livUu Dalai I Jaa l*St) WR/AiL_l - UH010CAmalt 1 1) 4 comm* and KiraiNCK HO NAME OR INITIALS BATE OF BIRTH 4 COHFAIIT 1t 7 * 10 It 11 11 14 FACTO*T FIBBT TC tirOSUAE DATS OF DIAGNOSIS ACS AT DIAGNOSIS TBABS OF BSPOSOBR TO DIACMOSIS TRASS OF urosuRE DATE OF PEATS HISTOLOGICAL CONFIRMATION ESTIMATED EIFOSURR LEVEL OCCUPATION IS OTHER CAREER HIGIILIOIITS It OTHER OtBBfEMIt ccrhanv 0* 10 (M10SH glrae aa Caaa 11) II (HIOSR gtree aa Caaa 10) 12 00.00.14 cm Marl 20.02.tt 16.06.It 41 IS u 24.01.70 Taa High paaha I) fra poly- worler lacl 171 auto clave claaalng Coacral rooa l rr 00.00.11 CUN Karl 0l.0l.tl 00.01.72 40 It 10 07.01.77 Taa Sigh faaka 10 gra folg- uorker lacl I72 aula* clava claaotng 00.00.1* Hacbi Burg- 10.10.31 2S.Ot.77 47 11 21 2B.Oi.77 Taa High 1 rra aulo hi him ci aw* claaaar 1* rn filter operator 00.00.IB Djraaal t TrotaAorf 00.00.61 00.10.77 1* It t 07.10.77 Taa I PTC Hamrfictur* Antoclav* worker for f gra 10/7S Coal1 road Average aapoaara ft rat pra ISO ppa, occ 1000 ppa Ni 3 jrn w, 7$ ppia Lilia ft av 33 pp AviriRi cxpoiura lint * gra ISO ppa. occ 1000 ppa. Laat ft ar 75 pp*. aw tartar of 21.04.71 96000 L s*u Z.60S01 SSH . r*(* n suhuk IMPEEIAL CHEMICAL IM0UATEII9 PLC LIVE* lailoniHU Caeca - (Eavlea total I Jaa lilt) Wl/ULJ - LANGIOCASES.l 7 --J----------- -------5--------- -------1------- comm aw tBrUIKCB s NAME 01 INITIALS DATE OF 11 ITU 1 GOWAHV -------1------- I rilST TC rAcruir EHMORE i -------- J DATE Of AGE At DIAGNOSIS DIAGNOSIS I --ns-- --n-- ---------- Ii----------- --n-- --n-- -----------n---------- ---------- re---------- nut or ElfOSUU TO DIAGNOSIS TEAM Ot atosuu BATS or DEATH HIST0L0CICAL CONriSHATlON ESTIHATSD EIKUUEE LEVEL OCCUPATION OTNES CAHEES HIGHLIGHTS OTHEl COHHEHTS CItHAHt 1) 14 ll (IIUI Elvaa till a aa Gaaa 11) tl 00.00.14 Laaaa toltahut 00.00a60 OS. Ot.lt tl IS U If.01.71 Taa 00.00.11 Nackar lur(kauaa. If.10.11 Of.10.71 41 11 00.00.11 Dpaaatt Tieladotf TOiir 07.ot. ll (Laibach anapatul ASL at rak 1171 laparatoap) 41 ' 11 Hat aa Aaslaearcoae l. kla lattar af 11 11 II, Hr frAltai aalA thla aa a flattaoapltbelkarilaoa tot Spalaerohra v (a carctaoua of tha aaeophatwa) at attrlbutakla ta VGH A oat recotalaet u ludeet- tlal tlaaaaa 1! ' ioor Taa 1 Aatoclaaa claaaat aat worker. Dr lac operator. La tar akllt 1aater 14 6T.4I.JI Taa Risk Autoclave ASL aat worker till Hepatocellular IMA. Carelaaaa Leader aat aaatar r H Seat latter at 10th Jwaa 1100 aaelaatag data Ira. Hr H r Trledal af SG Gbaala r II Seat lattar at 10th June lfBO aaelaalas tata fra. H r Frieda! af SG Gbaala wlthtrawlns thla caaa Aa|laaarcoaa coallraat Of/71. Saaa fatall af thla A alaa carea f, 11. 11, It A 17 Elvaa la ItEH Ha port far 117S Abeloaarcaaa caaflraat, full tatalla af lllaeaa alaea torch 1171 ilvaa la NIH tot leap Bap far If7t. Different tatalla |lvaa la VC Aaaaclatet Olaeaaa bp Laibach cat toratallar (HOI) all. Fall I) 3EIHA1R Ifceot 3 IHFE1IAL CH1HIC4L |N0U1TIM rLC LIVE! Aofloaarcou Caaa* - (Inlw Dalai 1 Jaa 1904) ME/AILI - UHGlOCASKl.ll 1 i 3 4 S( i i 10 a ii 11 14 IS COUHTBT ANO BEftEEMCE HO NAME M INITIALS DATE Of tin OOHfANT rAcroav HAST vc tirosm OATS or DIAGNOSIS Alii At oiacikuii 1141* 09 iroiwt to DIACKOSIS mu or Krasina DAT! Of DEATH NIITOLOCtClL COHfllHATlON EITIH4TED ElfOlDEE LEVEL OCCUPATION OTUtl C4UE1 11CHLICHTS it OTIIEB OOMUHTI* CEEH4H1 II (HI03K ilaaa aa Caaa IS) 1* 16 10 it a 00.00.31 ByrneIt Troludarf OI.ll.il i4.oi.ia 41 li 00.00. ll lotchat Gadorf 00.00.35 23.11. J6 oo.oo.ii Oynaalt Trotadorf ll.IA.3i 66.Ai.Ji ii 'U ck6.oo.13 I|shI t Trotadorf 14.oi.il 00.04.ao 61 14 11 oo.oo.ii Dynaalt Trot *4 or f bi.Ai.ii 00.09.1* 66 11 ^roaouitcid clinical llv*r oo.oo.ii Dynaatt ayvtoaa) Trotadorf is. ib.si ii.6b.66 ... ^ ii u 11.01.11 taa it is.li.n Taa 16 n.oi.ao Tab HatAiMBlof ASL 11 19.16.ao 1st Haaaaatta EodotkeIlaaa f liver Milk Hataataaaa 11 n.66. Taa Kaaeanfle Eedothel leu of llvar Mich 11 ot.li.ai Taa NataataalnE ASL Bilk letoclave worker Bilk Autoclave Worker Autoclava Worker Bilk Autodm Worker No Aaitoaareoaa conllraid. Aaaual report ef tba Mortk Ihlaa Heatphalli Ha4leal loeyecterate lor 1911 poiaa 341-117 Ilaaa lull data'll. IU|I cfclorlda dlaaaaa dlainoaad 01-01-13. Oaaophaiaal varlcaa. ladloloilcetly contlrud aero oataolvala. Dr taacka lattar of 13-04-11 to Or tt 0 f Adaaa Dr laacha lattar ol 13-04-B1 to DrVIII AJaoa Bilk Autoclava Horkar aaA worked In drflnf atop Dr lABCtM lattac of 13-<X-S2 co DcNOI Adm HI Ik Autoclave Horkar OiarftahaoA, aukacquastijr lorauo Dr Raceke lattar of 13-04-S2 to Dr V G F Adcac 860001 STb 660001 S'SH >r*i* u IMfERIAL CHEMICAL IMMSTHItl ELC LIVEE l|butcu Cam ( Bev Bulat 1 Jaa 1)84) m/MLJ - LAHCIOCUEa.l) 1 1S * count** Am IKPttlNCt HO uhi m INITIAL* BATE W IBM CEBHAMT 11 MV 00.00.11 4 cowm Hacker s VACT0B1 Ltlg* ftMWU t VIBST VC BEvosma ms 1 BATS or BtACNOSU 14.01.1) a ACB AT B1ACNOI1B St f TBAEB OV BIFOSOBB to B1MSN0B1) 14 10 n VEABB OF datb or BiroauBB BB4TB ii is.os.ai 11 11 14 IS ISTOUkOICAL C0HF1RHAT1OM ESTIMATED EirnsHB LEVEL OCCUFATIOH OTMEB CAREER HICHL1CHTB Taa HlBb Cheat atry * (>100 rr-> Worker 14 OWE* C0HH8NT* Fral CaSttkl atataa aetaetaalaad. Frledal latiar 1).04.11 14 ML 00.00.IB Hacker brr 1)4) 11.10.11 14 1) it ia.os.ai Taa Hlfh Autoclave hllM| (>100 ppO Cleawr Frol EJar (Nualcb) laltac 21.01.11. Trlada! iRttar is.04.as IS E.Sch 00.00.11 Hackar lurg* mo ia.o).ai sa 11 tl 14.01.B3 Taa Ml|h rolyclave Worker aa4 Autaclava Claaaar Fra( Balaatr (Mulch) Trivial latter D.04.B1 1 m 00.00.11 CUN Mail 1053 14.04.14 34 11 ii ii.it.ai Taa Hlah bljnatkar Chroolc Hvpatltla (Lalhacb). Frledal latter l).04.n 11 HE oo.oo.ia Drawl ( Trelederf ISIS la.ot.n SS ta ta 01.01. B4 Taa Hl(h 4utoelava Clour till 1)11 Lalhacb. rrladal latter D.04.BS fag* ITUt IHTBB1AL CHEMICAL IHOUgTBISg rLC LIVER la|lHiKOU Caaaa - (IhIhi Datal t Jan l)li) UH/ASL 1 - LAHOIOCASgg, 1 1 s 4 s6 1 B B 10 u 11 11 14 IS 16 COUHT1T AND IPKUHCX MO KAHB Ot INITIALS DATE OT BIRTH COHTAHT FACTOAV riUT vc EXP03UU OATS OF 0IACH03I8 ACE AT DIACH0S1S (EARS or EirOSUER TO DtACMOSIS TEARS OT EirasuRE DATE OT DEATH HISTOLOGICAL COHHRHATIOH ESTIHATED EXroSURE LEVEL OCCUPATION mu 01 (On NIOUt aupplaaaotarp Hat) LG IS.06.34 TARSAC HI ra Venice 00.00.AS 1B.04.1I 16 06 01 16.04.71 IVaa rvc U| avtrodir OTHER CAREER HIGHL1CRTB OTHER COMIEHTS Prlnnry tinour ijr have beea pericerdlun. Not hoeo* geneou* with other ceeee* * A* 01 SI 01 va 13.11.IS MaattillOR Fait* 00.00.ST 11.11.11 M*iglt*ri 14.01.10 Solvay 00.01.SI 10.01.1$ 41 SS 04 Ft 10.01.11 ANIC liVtHAI 00.04,5* 00.01.61 41 OS C DimiIa IB.01.11 FAHSAC Kir* 00.00.61 01.01. SI Vnlca 46 IS 06 IT.11.71 Taa rolpmrk.r "| It it 10.07.75 Y*b High Aataclaaaar 1*71-5 did B pra (mi a varlatp of ll) Autoelav i Joba oparotor lacludtog 11 pra (1B6I- PVC packlag. 11) ee 11 it 10.01.61 Taa 11 pra - 1 ft Never cleaned Vatp High Hawmmr operator autoclave*. Sen paper by a* S III - CNIAPPUIO at ttoa-*oher Hadlua 2D yr - ol Had Lavoro Coneuned AuIocIavi Vol A <1902> little 4 pra - operator A pp 515-561 Low other dutlii alcohol* No AOL, In auaptMe lon polyair* laatlon. Aim Porenen In Man Dept nine* 1*75. 16 t 06.04. n Taa Hadtiaa-1 Dag aitrudar High 1B67-1B7S Coaaarctal Dtp! IB 74- IBS1 S TagllaLuaga talaa of 1 Aug IBB) * Saa Hal tool M ill Lavoro 41 pUl, IH4. Further datai la la 1 at tar I roa Dr Hootoaano of IARC m April lat IB61. ** llw aaa Hat tout and RoodtoeIla la Acta Oacotoglca Vol t HM pagaa IS - 41. 00i.0L S?d lOLCOL S9d t h|i It JAPAN IMPERIAL CHEMICAL INDUSTRIES PLC LIVER Aatlaaarceaa Caaaa - (Raalaw Dalai I Jaa IIM) WI/ASL_1 - UM0IOCAHt.il 1 1 1 4 1t 1 0 S 10 II 11 13 14 11 count** ANB lUtlMCI MO nun ot INITIALS OATS or SlftTtt COMPANY factory HAST VC siposuar DATK Of ACE AT ftlACHOftia 01ACMOS1S YEARS Of sirosust TO M1ACNOSIS YEARS Of RIPOSDRS OATS Of MEATH HISTOLOGICAL COHf IRHAT10M BtltMATEO RSfOSORR UVEL OCCOrATION OTHER CAREER MICMLICUTS It OTHta CQtMBHTI JAPAN ** * Ml TonoJI 01.OS.11 KUaul Raaova OOaW.53 UalO.M 53 It 13 14.10.H Yaa ETC Aaaoe 13 Era aata- Hurt Taatau ai;a aet claaa (aa coaaaat Rama. claaaar Re 3*0 m Aaaac) * Jafaa Tlaaa 1144 aaalfaaA ta IaAIcatat Slffaraat aa 15.10.11 uark alaca aapaauraa hat 111 aftaa at baaltb 3000 ppa up ta 1S14 Jafaa Tlaaa 11.10.11 t Japaaaaa IK Aaaaa lattar af 3l.01.lt 01 flO 01.00.30 00.11.IS 10.00. It 31 11 13 10.OS, It Yaa Hot kitown la palpaar- taattaa wrk laelutInf autaclara elaaalRR Japaaaaa FVC AaaoeIat Ian lattar af 31.01.lt * la Hi lactar al lat April till, Mr Mantaaaaa at 1ARC ia|i Japantn Hlalatry a( Laboar |l*a Mata af Alasaoala - ll-Ot-14 ARa of AtaRaaala - 11 Yaara af aigaiaati - 11 fat* I' IMPERIAL CHEMICAL INDUSTRIES PLC LIVES lailMunu Cans - (Raalaw Data) I Jaa IIH) WM/ASL 2 - LMUIOCASIt.il . 1 *________ 1 COUHTBV AND rsteerhcb NO nuts o INITIALS i DAT! Off HIT* 4 COMPANY S * ? la ii 11 11 14 fACTOAt NEST VC Birosuts PAT! or DIAGNOSIS ACE AT DIAGNOSIS YEARS Of (IPOSURE TO DIAGNOSIS YEARS Or Bxrosuii DATE Or MATS HISTOLOGICAL CONTI RHATION ESTIMATED tlfOSUEE LEVEL OCCUPATION 11 OTHER CAREER HIGHLIGHTS It OTHER COtHERTS NORWAY 01 All 11.11. IS North Hataya 00.01.so 11.11.II St 11 it 04.01.11 Yaa Hl|h raiaaaa S EyAro Aataclava aayaralaat CaaflraaS hy Dr YfclloEaaaaaa *( HR. At APHE Ntt *f t Jura ISIS Hr P Saataaa atataS that AN ha4 baaa a uaLti at a tait-uy taaa. VCH 4 rvc aara aada la aaaa bulISIns* lha VCH naa aata froa aeatylaaa ' Eot-eot s$d ZOIZOl S9U h|i II WUH lHKIlAL CMHICAl fNOWTHlM 1LC LIVE! Aa|loaarcoaa Caaaa - (taviav Data) 1 Jaa ItH) WI/UL_1 - UMIOCUM.il 1 1 1 4 S4 1 0 10 li 11 IS 14 IS 14 cotnrm and iikumi HO NAME oa INITIALS Bin or B1KTH CONfANT TACTOAT fltST VC Eirottwt DATt or OlAGMOBIt Ml AT DIMNMII mu or uroimt to 01ACNOS1I tout or tirtimi NATO or HATH HISTOLOGICAL CONflRKATlOH RSTIHATEO iirotuoo LEVEL occurATION OTHER CiUtt ICHLICUTS 0TNI1 OOMHWTt OMOPEN 01 HU 11.04.11 Eaaaaord (oadaaall 14.00.SI JOalO.M 41 1* it 10.10. M laa Volfuorkar 4 01 OL 11.11.11 Eaaaaard ftmimll 00.01,4S oo.oHon 41 11 li 14.00.11 Taa Hltb TCH pradactloa Hr IJaalla*a lattar of It Harcb 1910 caaflraa IL uaa a aoaoaar workar ubo uaa haavllp aapoaad, prabablp avaa aora ae tbaa a aoraal raactor claaoar 01 HE 10.04.10 Eaaaaard toadavail OO.OS.41 10.01.14 4S 1 ii 10.01.14 Taa Ul|h folpuarkar 04 AL 14.11.14 KmnoN tuadaaall 00.00.44 ll.OS.ll 41 11 li ll.OS.ll Taa ntoh 104 4-1 SSI polpaar- laatioa uorkar (11 prat 4 1950- 1911 faroaaa 09 fra) la ft rat 11 pra of aaployaaat bad baaa baaatlp aapoaad. la 1914, llvar abnaraalltf and aacroata dlafBOaad. Data coaflraad la Or 0 Opraa lattar 10.0. II to ctric OS 11.01.1* Eaaaaord Suavail II.OS.44 11.II.00 41 It it 11.11.00 Taa Nl|h - 1944-1910 4 faara Lew - caatrllufa aparator 10 Taara 1910-1900 drlar aparator Lattar af lad Ha* 1901 fro* Or David Oft a* * la hi a laUar o( lit April 1901, Or Htmtaaaaa si IAIC aapa la Swedaa'a National board of 03 Haaltb (ivaa 10-01-10 aa data of dlagaoala for Caaa 01 aad 1S-01-11 for r*i* >* M ghaat I UtrStUL CHEMICAL IHHimilS Ptc LIVER IntUMnoH but - (taaiaw Batai 1 Jaa 1*86) MM/ASl_l - LAMCIOCASEB.IA t H COUNTRY AW IIPUUCI HO 1 NAME 00 INITIALS 1 un or IIBTH 4 COHMIlf 16 ) 0 * 10 11 11 11 14 FACTORY riur vc EXPOSURE DATA OF DIAGNOSIS ACE AT DIAGNOSIS YEABB or EXPOSUBE TO DIAGNOSIS TSASS or sxrosuii un or DEATH HISTOLOGICAL COMPIAHATIOH ESTIMATED EXPOSURE LEVEL OCCUPATION 11 OTHER CAREER HIGHLIGHTS 16 OTHER COMMENTS UK 01 UJ 10.04.01 1CI Hlllhwaa 04.04.44 oi.it.n ()OI * Calllat papar Mia 11.11.11) ii 18 ii oi.ii.n Taa 100 ppa 1*44-1 VCH Lea ant Marry (fttl 6 1*41-8 Orlar Lancer Colllar 1*40-61 1 >-0*074 pa par Autoclava pages 1314-S aajra operator 11.11.11) 1*61-66 Orlar Dubious 01 fakrlcarlee case 01 BJU 01.06.1) r lanr 00.01.66 00.11.14 ii Of i.s 14.11.74 Taa Bl(h AsUdava elaauc Expoaura Halted la 1.66 - *.6* 04 JSft 11.06.10 1CI lltllhouae 16.04.14 00.06.1) si 1) 18 11.10.1) Taa Hadlua- 14-1 Pre-war flab hl|b Oaistao Plaat packer II3MS any 11-6 vehicle Drlar llaat ulntenaece 56-SS \HV-U------------ Autoclava Ilah packer uarkar 18-61 Chargehand Orlar riaat 61-11 roraaaa C 1/1 Flaat frOLSOL SVU gOV-CO^ N| M iwciul cKtticu. nnmui nc UM/ASL_1 - LAH0I0CASE6.il Ehaat 1 --I----------- 1 -------1------- -------- 1--------- i LIVER l|UHrM Cam - (laalau Batei t Jan 1906) -------1--------- -------- 1--------- --i-- ---------- 1----------- -------1------- --n-- ---------- n---------- 11 --n-- ---------- n---------- ---------- n---------- OQUNTRV AMD RErRREHCt MO BK OS RAMI 01 IMTIALS JK DATS or BIRTH 10.01.14 At cir ' "Till OOHFANt ir *r rACTOtt lorry la tty rust vc EtrasURI oa.oi.ii [ill DATE Ot DIACH0S1B 00.10.79 09.01.00 ACE At TEARS Of B1ACM0SIS BirottEE TO ` OlACNOSIS ts 11 UAI II ' ' TRAM Or BATE OT EiroSURE DEATH 11 19.11.79 11 61.61.H UTOUMICAL COHriRKATIOH HT1KATEB ttrastwB LEVEL OCCUTATIOM 1911-51 Volyeleaver 1911-11 Lataa 1911-60 rolyfloor 1960-64 faly Chartahaat 1964-70 Qiarlat ayarator 1970-71 Briar operator 7 yra Rely near Operater 1 yra OTUER CAREER MICNLICHTR 0TUE1 OQMHBMTt. 1 1! tea lt.ol.16 >6 Barr) IMS 00.00.to IT 1.1 11.61. to PoIy Floor rqlycteaaar 1961-1 Recovery 1961-1971 1 61 WTM SOOT ir tarry It.ot.so i>.tl.6l U SI 11 il.ll.li ils6-lt 500 ppe 1960-1974 too rr> 1946-11 19)6-1941 JkuiMlm Motor Hocbontc oporotor lHt-l ISO ltSI-l*S7 ' Operator on Oiarg>M AcKtylam aatoeUva Proportion hitUlag 1927-1974 Moot shirt ouporvltor outoclnro bntlAlng - Nam eloooaA outoclovo* tut avparvlaor'a Job aatatlal out airing aatocUaaa to lorfact Ihaa tin 11 UK lhi*t 3 IMPERIAL CttEHICAL INDUSTRIES PLC LIVER lailourcwi Clin - (Review Ratal I Jan IM6) UPX/ASLJ - LAMC|OCASES,2t --[----------- --s-- --i-- --------1--------- --J --i ---------1 1 1----------- ns-- n ----------n---------- --n-- --n--------- ----------n---------- ----------n---------- OOUMTST AMD UFfllKCI DO UK Of MAKE M INITIALS EIGP RATE OP RIRTH 01.OS.IS COMPANY RP PACTOEY larrp FIRST VC tXPOSIIRX IS. 02. SO RATE OP ACE AT DIAGNOSIS *UIAGHOSIS 01.01.S3 SS ISAM Of sirosost to DIAOHOSIS V1ARS or EXPOSURE DATS or BBATO JJ if 24.01. BJ HISTOLOGICAL COUP IRMATtOH ASTIHATCH tirosuss LEVEL OCCUPATION OTNCS CAtCEl HIGHLIGHTS Hsdtiea Pulpworker 2 yaare on Acrylonitrile laaln Plant* Alao prior to 1950* A year* RAT alatonaocoa 3 yeara notor car palotahoy* 2 years In GrsvJas Dock. OTHER COHHIim ID CJT 04.04.4T w hill 1T.04.6S 01 OS H JT IS 4.1 16.OS, B4 Via HI|h - 11 Polpcleaner Heavy Roods laforaatloa oaths (500 Ifii-il. vehicle driver tlvta In fpa). Low- Sprepaidrlet until final 1 attar 1S soothe baitac 1 fil lllnese 1 B.06.B4 Iron (SO ppa). ls. Slow Dr 0 H J Medlui - down UUllaae 21 aontha ttrIfpar (200 ppa) operator IfiS-TO. 11 CLP OS. 01. IS RP lirif If.11.IS 02.06.SS ST If 16 01.06.IS Taa Hl*h faljrcUaMr IftS -if 1965-ta. Mad If-Tf Sirvlct Low Tf-01 operator 4S-69. Poly Operator 69-1$. LoadInf Dial J9~B2. 11 Jt 24.01.JT 1CI Hlllhouee 14.0f.ST 03.06.SS 4S IS IS 04.11.SS Tna Low lfST-Sf Spsre nan* Nl|h SS-74 6*44In* Low T4-SS floor lfST-Sf. Autoclave Operator lfSf-SS Letter of 04.06.SS Dr fast Salth and letter of 04.06.IS Dr D H 0 (vena Ooeopha|eal haerrha|a due to ooaopha|oel verlcea due to Aa(loearcoaa of llvot Lot tar 26.06.BS Or f 1 let 901-00 L S'SU ^oieoi stu rage 11 DU lliwt I IMPERIAL CHEMICAL INDUSTRIES FLC LIVER Angloaercoea Cimi - (Review Biatai 1 Jan 1004) OK ayatea ( Oataa MI - MONTH - YEAR MPI/ARL 1 I 1 1 4 30 7 0 0 10 11 11 11 14 13 14 COWNTRT UNO REFERENCE 00 NAHE OA MTI or INITIALS lira COMPANY PAcrav mat vc sxroaoas MTS or diagnosis AM AT DIAGNOSIS moo or oirosuai to OlOCNOOIO moo or urosuoi om or BROTH 1ST0LDC1CAL CONFIRMATION ISTIHATtO uroouu LOVEL OCCUPATION OTHBB CAREER ICHLICm onm COMMITS UK* 01 Sari 17.10.11 m Ldull* 00.12.40 01.01.71 41 14 ii 01.01.71 Tea farfca villa 01 10.01.13 MO Lania- 13.11.33 00.03.70 17 14 il 17.00.71 Tea wllla (NtOSH 10.00.71) 01 Uwr4 11.01. IS BM Loulr* 10.11.43 10.11.71 SO 10 10 10.11.71 Tea DinwMAI* villa 04 13.01.10 sro Lout a* 04.01.31 10.00.47 41 13 13 07.01.40 Taa villa Fat Cleaear (Block Jaaa 1074) y 31 Meter? given BalllaB Bteaa la Aauala NT Art ACAD SCIENCES Raf 1 HI Ac*4 Tat 110 (1070) af Be Eyny rage 190 In 1074 Fayar by Alaa Black B R Cattlne of Jaaa 1.7.74 OSHA F *1 rat Cleaner ( Block) Raf 1 Alaa Black JAM 1.7.74 F SJ Oat Cleaner (Cf Black) Loula*Ilia Courlet Journal 01-09-40 Fat Cleaner (Cf Black) Raf 1 Alaa Black Raf 1 Alaa Black OS 21.01.11 ro Laula- 10.04.44 00.04.44 31 10 10 00.04.44 la a vllU Fat Cleaner (Cf Black) Raf I Alaa Block Oi 21.11.10 FO Louta- 11.01.41 00.01.74 43 11 11 14.07.73 Taa Auatla WlI* Jena at US 41r Farce Fat Cleaner (Cf Black) Kef 1 Leulavtlla Tinea 11.7.73 Ratlref Ayrll 1074 Alaa Black 01 Oiaclaa 01.03.21 ucc T Saart S Charla- 17.00.44 00.00.40 to* 43 24 17 11.01.40 Taa Raf 1 01 00.03.10 Goodyear Niagara 07.10.44 00.00.41 41 13 IS 10.00.41 Taa Raf 1 r.(. n INU Miait 1 IHPKK1AL CHEHICAL 1N0U9TII1S PIC LIWI ln|lourci Caaaa - (Mwlau hill I Ja 1964) UK i|itw at data# UK - HOMIl - lltl tVI/ASL_l - I.ANCIOCASIS.2 B 1 A ooutrm tw BEFEBEHCB HO i HAM! 01 INITIALS i DATE OF mni 4 1* 7 10 11 11 11 14 COMPANY ' FACTORY FIRST VC EIFOSURS BATE Off DIAGNOSIS AM AT D1ACN0SIS TEAKS OP KXPOSUBI TO DIACBOSIS IBABS or EXroSUBE RATI or BEATS H1STOUMICAL CONTINUATION ESTIHATEO EXrOSUBI OCCUPATION LEVEL IS OTHER CAREER HIGHLIGHTS it OTHRR COHHENTR us* M Rayaoad fiittlr IIatari 0B.11.11 iro Loolrvlllo ia.os.4i 01.01.74 41 1* 10 It.OB.11 Goodyear Hla|*[* ll.Ot.SI 00.0S.4B . IS 11 17.01.0* floodpait HI agara 14.10.44 00.01,70 tl- 11 Francla A 17.11.IB PI [ton* lotUtwm 11.07.4* Ol.OS.t* lichiH ra SO 17 11 10 ii Richard 01.11.11 ucc Edwa rl Claodanla 9 Cbailr 11.11.41 OO.OS.74 ton SI 11 14 11.01.75 It) 1000 ppa li( 1 ba* mt ll|ur*i ra (Uit ipown. Lout*!! la Tlaa* 1*. 10.74, 11.1.7S, 10.1.74 17 io.os.ta T.a Baf 1 11 It.01.70 laa Baf 1 1* Ol.OS.t* lea Hlfti 10 yra ID fra aa Utility A Rf 1 + latter reactor p Sarvlca op, of 26 April (not cleanar Baar IBIS Iroa - aaparata Dryer op* luaaall A Fart craw claaaad Strlpplag op* to J T Saawall autoclavaa) 1 yra prior of HCA aarvlca In tyra plant It 07.04.74 lu 1000 ppa Oiarlaatoa Dal Ip lull 71.7.7S 14 Havar dl*t~ aaud aa aaa~ loaarciHM al 11**[. Ia(antlaa |lu la lattar 11 Hip l*B* froa J 4 St*. IS Accountant) ASL - No avldaaca of YCK aapoaura* 8(H(H STd 601001. SS ft|< 14 VSA !>> 1 1HFERIAL CHEMICAL INDUSTRIES 7LC LIVE! tailautcm Caaao - (latliv Dalai t Jaa IIU) BE lyotaa sf data* Ml - HMRM - YEA* UPX/ASL 1 - MNClOCABBS.ll ~ 1 1 1 4 1t T a 10 11 11 11 14 11 COUNT*! AMD lEfEAEMCE MO KAMI OB INITIALS DATC or HATH COHfAMT rAcnmi II1ST VC BirOSUBB BATS or uucNosia AGB AT eupMoaia TSAIS or ElfOSIM TO DIAGNOSIS TSAIS or UrOBBBB OATS or MATH HISTOLOGICAL COMTIBHATION ESTIMATED BirOSOBB LEVEL occunnoN OTBEB fifty* MICtalGIITt It OTNEB u JaM* 04.II.1T tie Loala* 01.01.10 00.00.4* 41 1* 04 17.01.4* Taa Havard *111* Laul*- Taa *mf 9 IT 0i.01.lt BIO *111* 11.04.11 11.10.T4 41 1* 1) 14.10.(0 aa tl.10.T4 but aa yoot-aortaa It.10.10 1*11-4 VCH poliaarlaatloa Troa 1*14 Tabla 4 la oamrda la Uagoaar Aray aat otbar Taatlaaay ta aarvtea. <4-10 Aray US Banata Coaflraat ta M M Johaaaa Ur OT.OB.TB Or H M Johaaoa lattar of 14.1.11 caaflraol daath t yaora altar It Ottrll* 11.04.10 WO Avoa Laka 11.0*. 14 00.00.Ti 44 11 11 01.11.11 Taa 11 *ra Navy Arthur autacloaoar 0 yra oa Eatal Tyra Itora plaattclaar t Carboaat aparttloo CoallraoA la H H Jahnoaa ltr OT.OB.TB 41aa Bat Hat Etaaa aaf. 11.01. Tt 1* virall 00.00.11 ucc 3 Qurlr* 00.00.41 11.04.T1 40 11 11 Dt.04.T4 Taa 1000 tfm CfcrUtlaa com Ml llloaoyart Sua Oaratta 11 Juaa 1*71 diarlaataa Dally Hall 11.7.71 10 1I.0B.IT CooJyur 00.00.11 10.01.T4 10 11 10 30.01.T4 Taa HI08* lattar af 11.10.7* 11 Cheat ar 01.09.0* UCC Ctiarlr- 00.11.44 Early TT AT 10 11 01.01.TI Taa Nlnkla tOQ 1* yra with UCC at SC Ratirat Maua ralaaaa 11.1.77 r>|i 11 USA Shaat 4 IHFEEIAL CHEMICAL INDUSTEIBS PLC LIVES Anfloaarcoua Caaaa - (Inltv Data) 1 Jan I ISA) BE ijaiw of ditM DAI - HOHTH - (UK UM/ASL_1 - LAftGIOCAgEB.lO 1 ii ClOEUINBNTOMRYJKANID USA NAME Oft INITIALS DATE OF K1BTH 4 COMPANY 1 PACrONY 4 EUXHrOSSTUKVEC 7 DATE OP DIAGNOSIS 0 ACE AT DIAGNOSIS RTDEEIPAAOGRSNSUOOtSlPISTO 10 YEARS Of Eirosuts 11 DATE Or DEATH 11 IEHHIITOLOOICAL CONI ATION ii EESirOTISMUAETEED UVEL 14 OCCUPATION IS OTIIEB CAEBEB HICHL1CDTS 14 OTHER COHHENTS 11 01.10.11 iro Loutr* 11.07.47 00.01.74 si i 10 04.11.74 la a Loutavllla villa Tinaa 14.1.74 aald ha uaa tha 10th A* vlctln at Balia Lana at whua 0 had dlod by 14.1.74 In hla lattar ot i6.ot.ai Or M M Jolwnon condrua tbla la tha caaa daaerlbad by Oannahar Tanburro 4 Van In Pnb 1*60 An J Hadlctaa Vol 70 ol60 11 00.00.11 Great Ntthburf 6i.o4.it 04.64.71 16 is u 04.64.71 Taa Aoericaa Kata* Cbaalcal Corpiav 11 Charia 17.01.17 occ S Charla- mi 47.01.77 66 ii m 17.01.47 Cholaaglo* Htdliaa In 1*41-41 aoor 1S17-SR via M H Uliaalat Edward Hoara atoa (NIOSH aaya 14) earcoae (S Kaalaafct blfh (or 14 (ta. aolaaml off and on vinyl raaln labourer luttar of 10.1.77 to 24/J/7R) wilt and I6W-4J nap J Stafford dlaporaloo Nava baa* nlvas data!la vinyl raalna aapoaad aa loaa Eaataakl wilt drat raactor lattar al aa (Ittar cleaner 14/1/7* ha 1 par, than IIO becaoe R Ran1nek1 abl (t ahlft Uttar <5 Nov lR0) utility nan IIO feacaoa ufieali that alii ft utility H10SH will tan 16.tH.4S retain m regime alnce enployoeat uia tlila neoytaan terminated ay ba aeeoci- eted with ASL. N Uheatar lattar of 1 10/1/79 and Eoao Eanlnakl Ran 01 ____ l atar conf road la R 1 aolaakl let r of 5 Nov alar 1*60 ____ i _____ l _____ i______ lattara of 14/1/79 and S/ll/60 OUEOI' S^U uieot ssu h|< It US* Shoot 1 ---- 1i 1 cowtm AMD AETIACHCI HO u*i MAHE 06 IHITIAL6 DATE OF BIBTU *6 Join Barry 07.07.11 t COHfAHT OKI s TACTOCT LouU' villa 6 nut Ik EIKSU6E 01.10.4T 1KFEBIAL CHEMICAL IHUUSTtUt PtC LIVEt Aagloaarcoaa Cimi - (go*lew Date) I Jea 1166) T DATE OT DIAGNOSIS 6 a6e at SIACHOSIS TEAKS Of 8ET06UR6 TO D1ACHOSIS 10 mu or IKFOSimB It mu or MATH 00.00. TT (up to 1 root a altar tn(k) SI (death) 10 (Aaath) It 11.01.TS IT J L II.OS.It DCC Tarraat S Cbtrlr- oi.6Mt 10.11.T6 toa tl 16 1A it UVN Il.6t.IT ucc S Ctiirlr- o6.Al.44 at ii.1o.6t BCC t S Charlr- oo.A6.41 atM ilTSOi- Teaaeco N ealngtoi ll.6t.64 Cheatee la 01.11.76 6d.AS.AA So.ll.A6 41 Si 11 IS 16 illtt.il (HtOSH aaye IT ant C Dally Hall 11) 14 SS 6S.il.St SI 14 01.01.60 IT IS s6.ii. eo SI o6.ii.ii UCC S Charla- ii.ol.44 6i.6A.4l ' IS 1 SS 11 di.64.6i itoa w.............. ............... ............... -- MK aytea of lain UV - MONTH - THAI UTX/ASL 1 - LAMClOCASBt.Sl ~ u HISTOLOCICAL COWIEHATIOH IS ESTIMATED urosuiE LEVEL 14 occurATIOM IS non CAHEEH HICHL1CHT6 16 0TUE6 co*ms, Taa txpoaad ta Varloue iota aaaa degree la rvc to 11 plaata frea chaaleala cold rooa to but aala paato aapaaara rococory to waa to TCH, IK charging 6 Eaataakt latter of 14/1/T6 oad frof. Taakurro latter of 9/1// probably high operator to pa ota chorglag. Ill 4aguot IMS. Taratoatot oaployaoat Jan IKt Taa High Operator to Eapoaura ta 6 H Ukeater 10,10.Tt bulb aot ltr at 4 Jaa Ataporoloa IVC 1619 oad aanufocturo Cbarlaatoa tally Hall S0.11.T6 and 6 Eaalaokt 16/1/T9 Taa B Kttlaafct Itiur of */ Taa Eoalaokl Taa t - Uakeowa tblntanaaca 1 - Hlataal Hachanlc Lot tara of 19th Juno I960 A Stb Ho* I960 6 pro tloowbaro IS yra tailor bouoa Operator - * *F< . Taa High (but Chealcal Fraa IfSt to Dr Decay aot aa high Operator la l*)t Aliphatic latter aa raactor charge Cbcalcala 16.10.61 and claaaar reactor operator an4 6 H Wheeler would froa July 16T6 letter of aaparlaaea) to data 9.11.61. tAirfcad aa Toreaaa Alao Dr Dacay labourar (roa Aliphatic Chaalcal letter of 07.OS. 61 re Juua 1*41 Oparatloa data of daath. ta Hay (946 aad aay have claaaoA raactora la that tlaa 27 USA Sliaat A IHFERIAL CHEMICAL INDUSTRIES UNITED LIVER ABRlOkkrcMU Ckkkk - (Eavlau Data! 1 Jkk 1IH) OK IfltM of dltM dat - immi - mi UFI/ASLJ - UUknOCASES.il 1 i 3 A 3a 1 10 11 11 11 14 13 14 COUNTS! AND REFERENCE HO HAMS OK INITIALS PATS or . SlRTH COMPA NT FACTORY fiut vc urosuM MTt or DIAGNOSIS ACE AT DIAGNOSIS mis or Eirosoii TO DIACMOSII TEAM OF UrOSIME DATE OF DEATH HISTOLOGICAL CONFIRMATION ESTIHATER EKPUSURE UVEL OCCOFAVION OTHER CAKEBS HIGHLIGHTS OTHER COHHEHTS ' UR 31 C V Cl roue 21-02-01 None**to 1 prJbrul 13-10-31 00-07-15 Hill 71 * III 13 S Fertueoo ot-10-2? in Laulwtlli OHM-51 11-05-R1 34 III It Nr Ryrua 21-01-lt RFC LoutBelli i 1133 01-11-11 41 US 13 m 01-01-11 occ 8 Chart*- 11-OJ-tt 11-0J-11 aeon 71 2T-0A-11 Th Cioival Aabtab Tin iiul UU lubber Co 11-0A-it 1I-0I-I1 30 it 14 17-05-10 An aatopay The death 1*40-1)51 (la PVC vaa doaa knA certificate Virtual Joba kutoclkvk laaMd Iktk (ava In polyner kTkk> ekukk of Hr Glroua* u mafic t ii ri death (Ivaa ueuel SUTVAB kk occupation LUSTREI `Aasloaarcoaa aa battle 1131-1*44 operator ' Varloua Jobk In In nod 'ctMlcal* around PVC Inductry * autoclivaa 1*44-1*71 Varloua clarlcal Juki In PVC polyaerlaatli in facility/ Rattrad 01-03-71. loforaatloa |l*an la 1 attar of It February 1*12 froa Dr Ualtar C arnaa of Naoaanto SprlnRflald to Dr A Nunn of Hokaaato Europa. ii 11 All*k Vkk Multiple lobe Including Foly Operator -I Prof Taaburro lattar at 12 Au| 1*12 * Dr H N Johntoo lattar of 21 Fab t). 17 10 04.01.11 Tea roly Operator -1 Autoclave Clkinar 1*33-45. 1)45 lift iro to bkcona a Clariyaan. Dr 1 1 Johoaoa lattar at I Nov 1*12, II Fab 1*1 aod * Aur DM. 11 It 11-07-11 Taa Hl|h fro* 1344 ta 1355. Hkdlut (rok 1*55-1III Dr Dacay lattar of 3 lept 1)11. 17 17 Allva Vkk Hodarata 1)54-14 labnurar 1*34-57 prod balper 1957-70 oparatar 1*70-75 alectrlclan l*75-praaaat aparatar R U Laundrla lattar of 12 lapt Dili apottaJ at aadlcal Hay 1)11. Taallnp cnauaacad Nay 19U zntoi s'?a euetu svu l*a Mi Ilian > 1 1HTUUL CHEMICAL IMDUSTNUS LIMITED Live* ln*loaarcoaa Caaaa - < Barlow Data) I Jaa 1*W) UK i|rttM o( Ml - HOUTM - !U* WI/AILJ - UMG10CAUStU t i 3 4 5a 7 a * 10 ii n 11 U 15 U COUNT** INC ur;iuci MO HAM OA INITIALS un or 11KTH cchpany fOCKHIT VISIT VC mmi MTK Of ouGHoaia tea oucHoaia nua or uroauta to oucmaia mu or uroauaa un or nun HI8TOLOC1CM. C0OTUMAT10H iiriMmo xroauia LIVKL OCCUPATION OTM* citaeo HicNLicura oniei OOHHKNI1 . ua ii Hr J i* oa a* ant LmJi* mi ot oa ai M ll ii Oi.OB.M laa Hl*h Ho rhad Fa;to* ilUl ra(ularly la rVC araa. la tha aarly laya uaa a taactat claantr 1*51-71. lafanMtlaa alvaa la attar 01.0B.M froa Dr H H Jahataa oa ii an 21 oa 22 tu Calfart 00.01.11 l*.Ol.M ti 10 10 la.io.n Taa l(h Norul pro- fraJaeta City 1*11-1*12 iriHlot (cm fcalpar lo nlor opiHUr, cIumI rMctociy i4 rteovnjr ami aa well ai clurflog operator. Tbroaho cytayanla aal laukopaal* alaca 1*7*. Coll traataaat (or arthrltla 1*71. Nodar Dr*a cara ahoat 1 aoalha halara daath, hal yaaaal taolarl yhyaleat aiar lootloo 1 aoatba aarllar. J Barr lattara of 12.10.M 1 21/01/15. r*t* i* IIK01UVU IHKB1AL CHEMICAL IWUSTEUS ELC LIKE iatlourcwu Cnsaa - (lav law km 1 iu 19*6) HTE/ABLJ - LAHGIOCASM,14 1 1 i 4 s4 1 0 10 II 11 IS 14 u 14 COUNTRY AND RirfRSNCK lio MAUI 0 INITIALS DAT* Of lUTtt COHrAHV VACTORY FIRST VC UPOSUtl OATI or DIAGNOSIS ACE AT DIACHDS1S mu or EiroSUBI TO DIAGNOSIS mis or BIMSIME DATS or DEATH HISTOLOGICAL CONFIRMATION ESTIHATEO EirOSUEE LEVEL OCCUrATIOM OTHU CARRES HIGHLIGHTS OTHU caoiEim. YUGOSLAVIA at OS.04.14 Ju|o split 00.00.SI 01.04.11 s 10 10 00.04.11 Vloll SAH1C at at pa pat In* Haaltk fatapacttva Vol 11, pp lai-iii 1*14 01 IS.11.11 JufO Split 00.00. so ti.oi.n 41 11 10 11.01.11 !** Unit 0] 11.11.11 Jll|0 riit 04.04. S4 11.01.14 4S 11 11 11.01.14 Ta** Vloll VCH EroAucEloa VCH Production Mo Mr Iittor of 3 Oct 1171, Dr l^liUi of HI05H cbao|d tho ItOtlM ol Caa* 01 to VCH producttM MpUyiOt Dr Splrtaa alao potlfloA Dew Can 03 alas o VCH production taorkar 04 11.04.10 Jugo Split 1S.I1.SI 01.0*.10 41 10 10 Ol.Of.TI lu Vtnll toaa Eaalaakt Lattat ol 19th Juna 1910 aai IAEC lattat of 1 April IBM meoi S9d sueov s*u Page 30 Incidence of ASL Cases Per Annum TABLE (Review Date - 1 Jan 1986) 1(7 2 The 1977 total includes US case 24 which is a Cholanglosarcoma. 3 The 1982 total does not Include US 33 and F IS who are alive. 4 The 1983 total does not Include US 36 who Is alive. HPX/iSF2 - LANGIOCASES ,35 Page 31 Distribution of ASL Cages by Country TABLE (geylew pate - 1 Jan 1986) 2 USA W Germany France UK Canada Sweden Yugoslavia Italy Czechoslovakia Japan Belgium Norway 35 *** 26 ** IB *** 11 10 s **** 4 ***** 4* 2 2 2 1 Total 120 * Omit ItOl - atypical case of PVC bag extruder. ** Includes GE03 aerosol can filler. *** Includes case US 24 which was diagnosed as Cholaagiosarcoma & US 33, and 36; and F 15 who are alive **** includes one monomer worker. ***** includes two monomer workers. i.e Western Europe North America Rest of World 67 45 B WPX/ASL 2 - LANGIOCASES,36 Total 120 911-801- SSd ZtLOJ. S$d Page 32 Pattern of ASL Caaea by Factory TABLE 3 (Review pate - 1 Jan 1986) (a) W Europe Of the 67 cases in W Europe, 57 have occurred in clusters at 11 factories. Of the 26 Genian cases, 23 have occurred in clusters at 4 factories. ASL Cases Dynamlt, Trolsdorf, Gemany Chloe Chimle (Formerly RP), St Pons, France BP, Barry, UK Hacker, Burghausen, Germany Kenanord, Sundsvall, Sweden PCUK, Brlgnoud, France CtfH, Marl, Germany IC1, Hlllhouse, UK Solvay, Tavaux, France Lonza, Haldshut, Germany Solvay, Jemeppe, Belgium 11 8 8 7 5 5 3 3 3 2 _2 57 NB: There are 32 pre 1962 PVC plants In H Europe; 18 of these have had ASL cases (Ref Table 8) (b) N America Of the 45 cases in N America, 38 have occurred at four factories out of a total of 54 factories:- In N America 43 plants have not had ML cases. ASL Cases BFG, Louisville, US BFG, Shawlnlgan, Canada UCC, S Charleston Goodyear, Niagara 14 10 10 4 38 NB: There are 28 pre 1962 PVC plants in N America; 11 of these have had ASL cases (Ref Tables 9 & 10) (c) Rest of World The 8 ASL cases are believed to be in 1 cluster of 4 and 2 clusters of 2 cases. MWPX/Vr 2 - LANG10CASES, 37 Page1 TABLE 4A (Review Date - 1 Jan 1986) Latency Periods (Years from first Exposure to Diagnosis) Country No of Cases Total Years Ave rage W Europe Belgium 2 35 17.5 France Germany 18 459 25.5 * 26 495 19.04 * Italy 4 74 18.5 Norway 1 22 22 Sweden 5 122 24.5 N America UK US 11 254 23.09 * 67 1461 21.80 35 886 25.31 * Rest of World Canada 10 204 20.4 * 45 1090 24.22 Czechoslovakia 2 30 15.0 Japan 2 39 19.5 Summary Yugoslavia 4 8 85 21.2 154 19.2 W Europe 67 1461 21.80 N America 45 1090 24.22 Rest of World 8 120 154 2705 19.2 22.54 * Of the countries with > jg ca8eS( Prance, UK and USA have an average latency period above world average, Germany and Canada below world average. WPX/ASL 2 - LANGIOCASES,38 . , evveov sw Page 34 DISTRIBUTION OF LATENCY PERIODS TABLE 4B 6US0I. S9U (Review Date - 1 Jan 1986) 0-9 yrs 10-14 yrs 15-19 yrs 20-24 yrs 25-29 yrs 30-34 yrs 35+ yrs Total Average Latency Period Belgium 2 2 17.5 Canada 3 52 10 20.4 Czechoslovakia 11 2 15.0 France 1 4 3 5 2 3 18 25.5 Germany 5 9 9* 3 26 19.04 Italy 22 4 18.5 Japan 11 2 19.5 Norway 1 1 22 Sweden 2 21 5 24.5 UK 1 4 42 11 23.09 USA 2 7 8 8 5 5 35 25.31 Yugoslavia 4 4 21.2 TOTAL 1 12 32 33 24 10 8 120 22.54 * Includes O 03 aerosol can filler WPX/ASL 2 - LANGIOCASES,39 (Review dace 1 January 1986) TABLE 4C LATENCY period of asl cases tabulated by year of first exposure MAE POSSIBLE LATENCY PERIOD YEAR OF FIRST EXPOSURE LATENCY PERIOD (NO OF YEARS) ARITHMETIC MEAN OF LATENCY PERIODS 47 1939 38* 46 1940 45 1 37,21,37,41 44 2 32_j38 244 - 34.86 7 43 3 38,14 ,32 4 28,11 ,24,20 ,24,34,39 718 - 26.59 5 27,22 ,28,29 27 6 21,29 ,31,26 ,28,15,23, 30,35 39 29,24 ,29,28 38 8 28,24,34 9 30,26,20 458 - 24.11 1950 26,22,31,19,23,14,33 19 1 19,28,17,28 34 2 21**,15 33 3 25.22 ,23,22 ,20,31,22 4 21,21 ,25,25 ,21,28***, 22 725 - 21.97 22.23 ,24,14,19,21,27 27*** 24,28 33 6 21,12 ,27*** 29 7 19.17 .15.13.16.28 28 8 18,18,15,17,20 9 16,21 368 - 16.73 1960 1 13,18,21 15,16,16,16 ,19,19,12 22 24 2 13.18,17.12 ,18_________ 23 3 16,17,20,21 4 16,17 180 - 16.36 5 11,19 11 6 9,18 19 7 16 18 8 9 13 13 1970 VIOLA 1 14 2 13 3 MALTONI 4 GOODRICH TOTAL 120 CASES - 22.55 * Cholanglosarcoma ** Aerosol can filler *** 0S33 and 36; and F15 still alive WPX/ASL_2 - LANGI0CASES,40 30 (/> o 00 ro o R&S 103121 Page 36 (Review date 1 January 1986) TABLE 4P LATENCY PERIODS of asl cases tabulated by tear of first exposure and geographical ' location MAX POSSIBLE LATENCY PERIOD YEAR OF FIRST EXPOSURE LATENCY PERIODS IN WESTERN EUROPE NORTH AMERICA ROW 47 46 45 44 43 39 38 34 33 29 28 24 23 " 19 18 1939 1940 1 2 3 4 5 6 7 8 9 1950 1 2 3 4 5 6 7 8 9 1960 1 2 3 4 5 6 7 8 9 VIOLA 1970 1 2 MALTONI 3 TOTAL CASES 38* 37,41 38 28 27 21,29,31,33 29 28,34 30,26 26,22,31 19,28 21** 25,22,22 21,21,25,25 22,23,24,27***24,28 21,12 19.17.15.13.28 18,18 16,21 13,18,21 15,16,16,16,19,19 13.18.17.18 16,17,21 16 11,19 9,18 16 21,37 32,38 14,32 11,24,20,24,34,39 22,28,29 26,28,15,23,30,35 24.29.28 24 20 19 17,28 15 23,31 21,28*** 14,19,21,27 27*** 15 12 12 20 17 13 67 45 23,14 22,20 22 16 17,20 8 * Cholangiosarcoma ** Aerosol can filler *** US33 and 36; and F13 still alive WPX/ASL 2 - LANGI0CASES.41 TABLE 4E Page 37 (Review dace 1 January 1986) PLANT START UP DATE LATENCY PERIODS OF ASL CASES IN SPECIFIC PLANTS (10 OR MORE CASES) NO OF CASES AVERAGE LATENCY PERIOD LOUISVILLE USA SHAWINIGAN CANADA S CHARLESTON USA TROISDORF W GERMANY 1940? 1941? 1939? 1954 12,14,15,19,19,20,24,27,28,28,28,29,29 31 11,12,14,21,22,23,24,24,26,28 24,30,32,32,34,35,37,38,38,39 12,13,16,16,18,19,19,21,23,25,28 14 10 10 11 23.07 20.5 33.9 19.09 33 (/) o 03 N3 N3 WPX/ASL 2 - LANGIOCASES,42 Page 38 (Review dace 1 January 1986) TABLE 4F LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT (10 OR MORE CASES) YEAR OF FIRST EXPOSURE !939 1940 1 2 3 4 5 6 7 8 9 1950 1 2 3 4 5 6 7 8 9 1960 1 2 S CHARLESTON USA 38 37 32,38 32 24,34,39 30,35 LOUISVILLE USA 20 28,29,27 29.28 24 19 15 31 28 14,19 12 SHAWINIGAN CANADA 21 14 11,24 22 26,28 24 23 12 TROISDORF W GERMANY 21,25 23,28 12 13 16,16,19,19, 18 R&S 103123 WPX/ASL 2 - LANGIOCASES,43 PLANT SUNDSVALL SWEDEN BRXGNOOD FRANCE ST FONS FRANCE BARRY UK BURGHADSEN W GERMANY NIAGARA USA Page 39 (Review date 1 January 1986) TABLE 4G START-UP DATE LATENCY PERIOD OF ASL CASES NO OF IN SPECIFIC PLANTS(4-9 CASES) CASES AVERAGE PERIOD 1945 16,19,27,29,31 5 24.4 years 1950 11,16,18,26,30 5 20.2 1939 1948 21,28,29,37,38,27,41,35 9,17,18,28,31,33,18,19 8 31.88 8 21.62 1933 17,21,22,25,24,13,21 7 20.43 1947 15,17,21,23 4 19 SPLIT YUGOSLAVIA 1941 20,20,22,23 4 21.25 R&S 103124 WPX/ASL 2 - LANGIOCASES,44 Page 40 (Review date 1 January 1986) TABLE AH LATENCY PERIOD YEAR OF FIRST EXPOSURE 1939 1940 1 2 3 4 5 6 7 8 9 1950 1 2 3 4 5 6 7 8 9 1960 1 2 3 4 5 6 7 8 9 1970 1 2 OF ASL CASES TABULATED BY YEAR OF FIRST r4-9 CASES SUNDSVALL BRIGNOUD ST FONS BARRY SWEDEN FRANCE FRANCE UR 27* 31 29 19 26,30 37 38 29 28,34 31,33 28 21 18 16 16 11 18 lJ 19 18 EXPOSURE AMD BURGHAUSEN W GERMANY a 25 21 22,24 17 21 13 SPECIFIC NIAGARA USA 15,23 17 21 PLANT SPL YUGO5 SLAVIA 23* 20 22* 20 m 4 * Monomer workers R&S 103125 WPX/ASL 2 - LANGIOCASES,45 Page 41 TABLE 5 (Review Date - 1 Jan 1986) Annual Incidence of ASL Cases (Date of Death) by Geographical Area 1955 7 1961 2 4 7 8 9 1970 1 2 3 4 5 6 7 8 9 1980 1 2 1983 1984 1985 TOTAL Western Europe North America Rest of World Annual Total l 1 l l 4 1 3 6 6 6 7 5 6 5 1 6 4 2 66* ** 1 l 1 l l 5 2 1 2 1 4 2 4 3 3 2 - 4 0 1 3 1 43** 1 3 - 1 2 1 - 8 l 1 1 1 2 1 5 3 2 3 5 8 5 11 11 9 10 5 10 5 2 9 5 2 117 Cumulative Total 1 2 3 4 6 7 12 15 17 20 25 33 38 49 60 69 79 84 94 99 101 110 115 117 - Key Events Viola Haltoni Goodrich * Includes G03 aerosol can filler but omits It 01 bag extruder ** Does not Include US33, and 36; and F 15. All Btlll alive. WPX/ASL 2 - LANGIOCASES ,46 92teoi S9U Page 42 (Review date 1 January 1986) TABLE 6 ASL CASE NUMBERS BY YEAR OF DEATH AMD GEOGRAPHICAL LOCATIONS (EXCLUDING ITOl) KEY EVENTS WESTERN EUROPE NORTH AMERICA REST OF WORLD Viola Maltonl Goodrich 1955 0 7 8 9 1960 1 2 3 4 5 6 7 8 9 1970 1 2 3 4 5 6 7 8 9 1980 1 2 3 4 5 Total FI G1 Svl G2 Nl.Sw2.UKl.It2 G3*** G4.G5.UK3 F2,F3,G6,G7,G8,It3 B1,F4,F5,F6,F7,Sw3 F8 ,F9 ,G10 ,G11 ,G12 ,Sv4 F10,F11,G9,G13,615 G16.G17 F12,F13,UK4,UK5,G18 UK6, UK7,G19,Sw5,G20,G21 It4,F14,UK8,G22,G23 G26 UK09,It5,F17,B2,G24,G25 UK10, F16, F18, G27 UK11, UK12 66 Cl C2 US8 C3 US5 t Cz2 C4,C5,0S4,US7 ,US10 US12.US16 US11 C6,US2 C7 C8,US1.US3,US23 C9,US13 US6,US9,US18,US26 US19,US20,US22, C10,US21,US24* US27,US28 Y1,Y2.Czl Japl Jap2.Y3 Y4 US17, US29, US30, US32 US31 US35. US34, US38 US37 43*** 8 ________________________________________________ * Cholanglosarcoma ** Aerosol can filler *** Does not Include US33, and 36; and F15. All still alive. i R&S 103127 WPX/ASL 2 - LANGIOCASES,47 Page 43 (Review dace 1 January 1986) TABLE 7 ASL CASE NUMBERS BY TEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION (EXCLUDING IT01) KEY EVENTS WESTERN EUROPE NORTH AMERICA REST OF WORLD Viola Malconl 1939 40 1 2 3 4 5 6 7 8 9 50 1 2 3 4 5 6 7 8 9 60 1 2 3 4 5 6 7 8 9 70 1 2 3 Frll,Frl6 Frl4 UK1 Sv2 Frl,Fr3,Sw4 Sw3 Fr9, Frl7 Frl2,Fr4 Fr7,Nl,UK8,UK9 Swl,UK5 G3** G15,It3,G26 G7,G8,UK4,G19 G11,G16,G18, Frl5*** G23.G28 FR10.G1 Fr8,G4,It2,G2,UK12 Fr6,Bl Fr2,It4 G5,G13,G25 G9,G10,G12,G17,G20,G22 G6,UK6,G21,B2 Frl3, UK7,Frl8 Sw5 Fr5,UK11 UK3, UK10 It5 G24 US24* C3,US27 US13, US29 C2,US19 Cl ,C5 ,US5 ,US7 ,US28 ,US35 C4,US3,US9 C7,C9,US8,US11,US21 ,US31 C6,US22,US26 US1 US12 US16 Y2, Cz2 US10, US32 US4 CIO, US37 Japl.Yl US18,US33*** Y3 US2.US17.US20.US34 US36*** US23 Czl Jap2,Y4 08 US6 US38 US30 Total 67 45 8 * Cholanglosareoma (US24) ** Aerosol can filler (G3) *** US33 and 36; and Fr 15 are still alive. WPX/ASL 2 - LANGIOCASES,48 qJJ --L o CO lO 03 (Review date 9 January 1986) TABLE 8 WESTERN EUROPE PVC PRCDUOSRS - SIAKP-UP DATES vb ASL CASES (CMETTPC G03 & It.Ol) R&S 103129 START-UP CDUNIEY NAME OCMPANY NAME IDCATION ASL CASE tUMBER TEAR OF TEAR 1st Exposure 1931 West Germany BASF Ludulgshafen 1933 West Germany Wacker Burgbausen 04.07.11.15.23.24 25157.54.55,53.55.69.60 1938 Italy Mantecatlni Acna 1939 France Rhone Poulenc St Fans 03.09.10.11.14. 46,48,56,41.43, 15.16.17 55.41.48 1940 United Kingdom ICI Runcom 1940 United Kingdan ICX Hlllhouse 01.04.12 44.54.57 1945 Sweden Kemsnord Sundsvall(Stockvik) 01,02.03,04.05 51,45.47.46.64 Switzerland Lonza Sins 1946 France Rhone Poulenc Rousillon 01 46 1947 Italy Montedison Porto Maryhera 02 57 1948 United KtnpjHnm BP Chan Barry 03,05.06,07,08,09 66.51.62.63.50.50 10,11 66.65 West Germany Hula Marl 09.10.26 61.61.53 1949 Belgian Solvay Jemeppe 01,02 58.62 1950 France Puk Brlgnoud 02.04.05.06.12 59.49,65.58.49 France Rhane-Poulenc St Auban 07 --------- 50 Holland Shell Pends Norway Norsk Heroya 01 50 1951 Italy Montedison Brindisi 1952 Italy Montedison Temi 1953 Austria Halvic Hallein France Solvay Tsvaux 06.13.18 57.63.63 Italy Solvay Ferrara 03 53 Spain Rio Rodano Hemanl United Kingdom BIP Aycliffe West Germany Hoechat Gendorf 18 55 1954 West Gernmny Dynanlt Troisdorf 01,02,08,12,16, 56,57,54,61,55,61, 17.19.20.21,22.27 54,61.62,61,55 1955 Spain 1956 Spain Monsanto Iberia Monzon Caiqsa ftiMnwrign Hispavie Torrelavega 1958 West Gernmny Solvay Rhelnberg 1960 Italy S C Ravenna Ravenna 04 59 1960 West Germany Lonza Waldshit 06,13 62,60 1962 Portugal Cires Oporto 1965 France Rhone-Poulenc Montlucoo Italy Pozzi Ferxandina West Germany Wacker Cologne 1966 West Germany Hoechst Knapsack(Frankfurt) 05* 60 1967 France Spain ATO Qiirnle Rio Rodano Bulan Miranda de Ebro Greece Esso Pappas Diavata Salonika 1968 Belglun Badiphil Antwerp 1969 United Klngdrm Vitiates Staveley Italy Rinrianra Cagliari. Sardlna 1970 Italy SIR Porto Torres Sar United Kingdom ICL Runcorn 1971 Italy S C Ravenna Ravema Spain Hispavlc Martorell Swedm Kemsnord Stenungsund United Kingdom BP Chan Baglan Bay 1972 Finland Pekema Svartback Holland D91 Beek. Limburg 1976 France Soc Art D'vinyl Mezlnsarbe 1977 Spain Monsanto Iberia Tarragona * Laboratory worker In Research Department PANSAC, Mira Venice, case not winded (it 05), due not knowing start up date of the Plant. R&s 103130 TABIE9 (Review date 1 January 1986) USA. FVC FBODDOBS ~ STAKE-OP DATES vs ASL GASES STAKMIP OCMPANY NAME LOCATION ASL CASE YEAR OF YEAR NUMBER 1st EXPOSURE 1939? *OOC S Qiarleston 07,13,19,21,24, 44,42,43,46,39, 27.28.29.31.35 41.44,42,46,44 1940? *HEG Louisville 01,02,03,04,05, 48,55,45,52,44, 06,09,16,17,22, 62,45,50,55,47, 26,33.34.37 47,54,55.53 1946? *OCC TSsas City (Partially closed 1977) 1947 Goodyear Niagara Falls 08,10,11.20 46,51.46.55 1948 firestone Pottstown 12 49 Odroyal Painesville (closed 1975) 1950 Monsanto Springfield 32 51 (Closed 1975 1952 Dow Midland (No PVC since c 1975) BEG Avon Lake 118 54 1953 BEG Deer Park (Formerly Diamond) 1954 General Tire Ashtabula 136 56 1956 Air Products (dosed 1984) Pensacola I Atlantic Refining Brooklyn(dosed late 1960s) Borden ftwifn Leominster (dosed 1984) Hebronvllle (dosed 1975) BEG Niagara Great American Fitchburg 23 58 Plastics (dosed 1983) Booker Hicksville (dosed 1980-81) Fautosoto Passiac (dosed 1984) 1957 Atlantic Tubing Cranston (dosed 1967) Termeeo Flanington NJ 30 59 1958 Keysor Century Saugus, Cal 1960 BEG Watson, Cal Air Products Calvert City 38 63 (closed March 1982 Re-opened Octol r 1983) 1962 Borden Termeeo Illtopolis Burlington NJ 1963 Conoco Aberdeen, Miss Stauffer Long Beach, Cal (G.osed 1982) 1965 Conoco ** Assonet, Mass (dosed by Olin 1975, see below) 1966 Ethyl Georgia Gulf Baton Rouge (dosed 1984) I Delaware City (Formerly Diamond) | General Tlre/Pantas Mt Pleasant W Va (dosed 1983) 1 BEG Henry, 111 1967 Stauffer A1HH Delaware City (Sold to Formosa 1983) *** Painesville, 0 | (sold to Roblntech) Booker Burlington NJ | 1968 Firestone Perryville (dosed 1982) 1969 BEG Pedrickton NJ Goodyear fVHn Plaouardne ** Asscnet, Mass (doeed 1975) (See above) (Formerly Conoco) 1971 | Conoco Oklahoma City 1 ___________________________________ WKjASLj. - IANdDCASES,50 Continued Page 46 TABLE 9 (Continued) PSA PVC PRODUCERS - START-UP DATES vs ASL CASES START-UP YEAR 1972 19)3 COMPANY NAME Mat Starch Borden Robintech *** 1974 1975 1579 1983 Atlantic Tubing/ Tallyrand Shintech Certain-teed Georgia Pacific Tenneco Firestone Formosa LOCATION Meredosia, 111 Springfield Painesville, 0 (sold to Georgia Pacific who converted to polystyrene) Cranston RI (Closec ASL CASE NUMBER 1982) Freeport. Tex Lake Charles Plaquemine. La Pasadena, Tex Plaquemine Point Comfort, Tex YEAR OF 1st EXPOSURE * My databank has no information on UCC before 1946 or BFG before 1950 ** Refers to same plant at Assonet ***Refer to same plant at Painesville. Allied plant never operated again for PVC after it was sold to Robintech. MB Some of the plants in this list were closed down, some have changed ownership over the years, some have changed their product. R&S 103131 WPX/ASL 2 - LANGI0CASES,51 Page 47 (Review date 1 January 1986) TABLE 10 CANADIAN PVC PRODUCERS - START-OP DATES vs ASL CASES START-UP TEAR COMPANY NAME LOCATION ASL CASE NUMBER YEAR OF 1st EXPOSURE 1943 (1941?) Goodrich Shavlnlgan 01,02,03,04,05 44,43,41,45,44, 06,07,08,09,10 47,46,61,46,53 1951 Monsanto La Salle (Closed 1! '75) 1957 Goodrich Welland 1966 Esso Sarnia 1979 Diamond Shamrock Alb Port Saskatchewan WPX/ASL 2 - LANGIOCASES,52 aj S CO o CO CO to R&S 103133 Page 48 (Review date 1 January 1986) TABLE 11 EASTERS BLOC PVC FACTORIES - START-PP DATES vs ASL CASES START-DP COUNTRY NAME COMPANY NAME TEAR Pre 1939 East Germany State Company 1941 Russia State Comps 1950 Yugoslavia Jugo Vlnil 1951 Czechoslovakia State Comps 1955 East Germany State Comps 1956 Rumania ` State Comps 1957 Poland State Comps Rumania State Comps 1958 1959 1961 1963 1965 1967 1969 1970 1972 1975 1976 1977 Rumania State Comps Hungary State Comps Rumania State Comps Yugoslavia Ohls Bulgaria State Comps Poland State Comps Russia State Comps Rumania State Comps Russia State Comps Yugoslavia Vlnilplastika Czechoslovakia State Comps Russia State Comps Yugoslavia Hip Rumania State Comps LOCATION Schopau Vladimir et al Split Novaky Bitterfeldt Icechim Osweicim (Dwory) Tlrnaveni Turda Risnov Berente Borsod Borzestl Skop1e Varna Tamow Dlerllnsk Rimnicu Vlleea Volgograd Zadar Neratovlce Kalush Area Pancevo Rimnicu Vlleea ASL CASE NUMBER 01.02,03,04 01.02 YEAR OP 1st Exposure 53.50.54,48 57,50 .......... -__ _m 1 WPX/ASL 2 - LANGIOCASES.53 (Review date 1 January 1986) TABLE 12 JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES START-UP TEAR 1950 1951 1952 1951 1956 1957 1960 1964 1966 1967 1968 1970 1971 1973 1974 COMPANY NAME Chisso Corp Kanegafuchi Kag Tekkosha Mitsui Toatsu Mitsubishi Mon Sumitomo Kag Denki Kagaku Nippon Zeon Toa Gosel Ryo-Nichi Nippon Zeon Nlsshin Kagaku Kureha Kasel Shlnetsu Kag Denki Kagaku Kanegafuchi Kag Chisso Corn Tokuyama Seksui San Arrow Kagak Sumitomo Kag Ryo-Nichi Shlnetsu Kag Chisso Corp Denki Kagaku Kanegafuchi Kag Kawasaki Yukl Mitsui Toatsu Nissan Kagaku Shlnetsu Kag Tekkosha Asahl Glass Toyo Soda 1975 1977 Central Kagaku Toyo Soda Unknown LOCATION Minamata Osaka Sakata Nagoya Yokkalchl Klkumoto Shibukawa Kambara Tckushima Uozu Takoaka Takeo Nlshikl Naoetsu Ohml Takasago Chiba Tokuyama Tokuyama Chiba Mlzu8hlma Tokuyama Mizushima Gol (Chiba) Kashlma Kawasaki Sakai Chiba Kashlma Yokkalchl Hayatsukl Sakata Yokkalshi Kawasaki Yokkalchl Kashlma ASL CASE NUMBER , 01, 02 YEAR OF 1st EXPOSURE 53. 58 R&S 103134 WPX/ASL_2 - LANGIOCASES,54 D to r Page 50 (Review dace 1 January 1986) TABLE 13 SOOTH AND CENTRAL AMERICAN PVC PRODUCERS START-OP COMPANY NAME YEAR 1953 Monsanto Mexlca 1954 Policyd 1955 Geon Do Brazil 1956 Elchlor 1960 ElacCrochlor Viplastic 1961 Indupa 1965 (SOC Paramanga (1967 start up PET Columbiana 1966 Carburo De Col 1967 Plasticos Omega 1968 Primex 1970 Polieasa Petro Dow 1971 Polimeros Mex 1975 Rico Chemicals 1976 Petroplas 1977 Indust Resistoc 1978 Huls Brasil Polychem Policyd 1979 PET Camacari LOCATION Lecherla (Mexico) Mexico City (Mexico) Sao Paulo (Brazil) Sao Caetano (Brazil) Capitan Bermudez(Argentina) Mendoz (Argentina) Cinco Saltos (Argentina) Paramonga (Peru) ) bartagena (Colombia) Medellin (Colombia) Mexico Puebla (Mexico) Managua (Nicaragua) Conception (Chile) St Martin Puebla (Mexico) Guyanilla (Puerto Rico) EL Tablazo (Venezuela) Tlazcala (Mexico) Cubato (Brazil). El Salvador Coatzacoalcos (Mexico) Camacari Bahia (Brazil) ASL CASE NUMBER YEAR OF 1st EXPOSURE < 1 R&S 103135 WPX/ASL 2 - LANGIOCASES,55 i tr Page 51 (Review date 1 January 1986) TABLE 14 AUSTRALASIAN PVC PRODUCERS START-UP TEAR COMPANY NAME Mid 1950a ICl Australia 1960a B F Goodrich Late 1970a ICI Australia LOCATION Botany, Sydney Melbourne Laverton Melbourne ASL CASE NUMBER YEAR OF 1st EXPOSURE R&S 103136 WPX/ASL 2 - LANGIOCASES.56