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CERTIFICATE OF ANALYSIS
SDBJBOfi Toxiaalojlaal imiUiiUoi of Pydraal W (HMOJ)
list# oonooBD rati Maaaaia Ohaadaal Oaapaay, Si. laala, Kaaouri. llMart* Pn>rt to, SHO
amxmna. ntoonraii A1) tToitovUorOalraLlDT,a, xaiaaalhfroand by tha latredaeiloa oAf--a--a--a--a-a-1r^a.dk'HMla doaaa af w
dilated aagpaaad lata iha aioaiaaha of maaga Dart ay atrdiktlMBa rate by
aaaaa af a rabbar aatbatar aitaahad io ikjfpadetjaia ayrlaga.
Aftar iha lapri Sad ai Attala daalgwd ia blaatot
Maya af rata tart haraby a^plyiag daia
Sir aalaalailaa at iha Uha
Salaatad aadaala (Ma ihaaa
liopalad aad aaaroaaapia wad-
aailaa aada af iha daaara.
Tha daia arc dwai la Ti
Taadaliy *y Skla Dadllatad Pydraal M ( af alblaa rabM.it la
Iha iraatad art* aaa aaaai
iha aaiaala aai
to iha alaaaly tlippad lataai tkla ordtr it flad iha Maiat lethal Data, ila aklald io raiard avayaratlaa aad
a ia grataat tua traa Xlafelas aff iha
Tha naalia
0) Ma IirlW Tha taarlag Tharapaatlaa,
(PS-103) m a
t| Vbodard aad Oalaary (4. af rbaaa. aad Baa. t Daa. XSWt) aaa aaad la aaalaailas FyMaal r- abaa plaaad aa lataai rabbit akla.
aaar a parlod af aaaaral daya aaa aaorad la Tahla III.
D) lya XrritaMaa Xa labblta Oadllatad Hiatal la tha owaai af 0.1 al. aaa plaaad la iha aaoyaMtiaal aaa af iha rlfhi apt af aaah af thraa tibiae rabblia aad tba decree af larltatlea aaarad aaoardlai ta Drelaa, Mbadard aad Calvary (J. of Pbaia. aad lap. Tharapaatlaa, Val. St, la. t, Daa. lfUt).
Tba ratalia art (lata la Tdbla IT.
MONS 037941
IMi Is t MmU npMt wbfafc aay bt Mart whau mu--J by jbyrtriMi sart kMBt rflftili, but is ws ba and la mf tea af ad--Mag wttaua -- p--m
CONSULTANTS TO TUB FOOD. CH1MICAL AMD PH AIM ACIOTICAL lMDOtTtllS
At Nn--ta **Aa*l C jmq, $% Lm1B|
U$mNLt$* mirtlii OirttfiMte of MmtljmU - fan 2, 14-0 Bnonra mocnowi (oaatinaad) I) T--r Inhilrtii
Nr Mtn Ml* rate n plaaad la --11 natal dM and a--aad Ar ala hoar* t* a oataratad a--aphora of pjMaal M faaaa hjr ji--la* a alw af aaawaaad air t--a* a aontalaar of tha flald pi--d lnalda tha ataMr. Ur praaanra -- 16 poMia par a--ra Irak. Tha aalMl* am aliaaka I far a--a-- of tmdaitp aad all -- hold far aaraa dap* abaarratloa -<-- a--aara. Tha data -- atoaa la Tatolo T.
MONS 037942
ft, IMJ, ttWIMl. saiaattfla luMlitM Oartinaata or iaalpaU - p*a J, I-1-S5
nui i
tkb. oral uim of pidraol r-9 (fb-ioj) ran uboratori ua
Anlaal Ho,
OIMBMIOat
At Ont l#t 4aya part af tea dlantaa a Utaatlaal
Lta aw
tantnl tiaa ai at a
U aatarite. ZB all prattemtar,
" " ` a# ~ t taadaitp <
) aanal aaaapt ter Imltattaa af Ua MpaUa
HONS 037943
T*i NMwnto CtaMdotl Oompmj, St. Laala, NLaaonrl.
Saiantifla lamliUi Oartlfioata at Antlyaia . Paga 4. 2-1-55 ` TABLE II
THE MINIMUM LETHAL DOSK 0W PTMUUL T-9 (FH-IOJ) BI SKIN ABSORPTION UklEbt Chaogi 5 Dajra After
MONS 03 7944
1i MoMmto Chaa&oai s>any,
St. LouIb, Mmouti. Sslaatiflo Aasoslatsa Oartiflsata of ladjali Pago $, 2-1-55
TABLE III
SHI IRRITATIOB IB RABBITS APTHI APPLICATIOB OP PUKAOL P-9 (PR-103)
Anlirtl Bo. Sa>
1 2 HU* 3 - Paula Asarags
Niuaarlaal gvaluatloa At Tha And of 30 Mia. 2b Maura 40 Basra 72
: : 1
discussion
811(ht radnaaa slth praatlaally ao adaaa uaa prui aaaraga aoora of 1.6 aat of a poaalhla 8.0. Tha Md saa dua to a alight Inaraaaa in radhoas third dajr tha aaapla bad naiarly dlaappa tha atsraga aaoaa had radaaad ta 1.6.
Pydraal (PM-103) saa oonaldarad to,
m
dimussiosi
Tha palpSbral aaijoaMa b6saaa sedarataly >4 d ahoasd a traaa of adaaa sithis thirty aiaataa far 4nVHi asaas of 12.3 out of a poaalhla 110. Tha lrla sad oarsaa sars hardly atfiHid. Tha asaas drappad ta 9.3 asamlght asd all ajas appaarad to ba norsal la 72 hours.
MONS 037945
Toi IMiato GbmiaA
Sill lMl>| M*SOa*li Sslaotifls Assoslstss Oartifloat* of Analysis - Pag* 6, 2-1-55
' TABLE 1
TAPCa INHALATION OF PTTWAOL 7-9 (FB-IOJ) BT RAIS
Inlnal No. Son 1
Fata SorrlssS
Coossntntion Of Pydrasl F-9 Vapors In CbMSnr
SatanM
Avarags Tanparaturs
Isolds
76.5*7.
Along* Bolotin Bwidlty
I a siAs
80.0(1
HONS 037946
