Document nkmgk1gJ5bdbeN5NZrEb3Zp4w

$ rr 3M Katherine E. Reed, Ph.D. Staff Vice President 3M Emironmental, Health and Safety Operations s e n a -0706 - 00 3y& p. 1 900 Bush A\enue. Building 42-2E-26 PO Box 33331 " St. Paul. MN 55133-3331 651 778 4331 AR _ 3&67 Certified Mail June 29, 2006 Contain* No CH C N T a im *0 C8/ Document Processing Center EPA East - Room 6428 Attn: Section 8(e) Office of Pollution Prevention and Toxics US EPA 1200 Pennsylvania Avenue NW Washington DC 20460-0001 89060000376 89060000 3 Re: TSCA 8(e) Substantial Risk Notice: Sulfonate-based and Carboxylic-based Fluorochemicals, Docket Nos.8EHQ-1180-374; 8EHQ-0381-0394; c> 8EHQ-0598-373 - Pilot Study to Assess Serum Fluorochemical Concentrations 'n American Red CrossBlood Donors, 2005. <== Dear Sirs: , t ^ TO ;H 3M is submitting this notice to supplement its previous submissions on sulfonyl and carboxylic*-3 based fluorochemicals. 3M has recently received the enclosed final report for serum " fluorochemical concentrations in a small sample population of American Red Cross bleed donors in 2005. The purpose of this pilot study was to determine whether general population PFOS and PFOA concentrations, as measured in 2005 in a small sample of American Red Cross blood donors, may represent a decline from prior general populations measurements made in 2000. The study found that there was an approximate 50 percent decline in serum concentrations of PFOS and PFOA consistently observed across sex and two age categories for both PFOS and PFOA. 3M does not believe that these data indicate a "substantial risk of injury to health or the environment." Nevertheless, 3M has decided to report these data, recognizing the ongoing work by U.S. EPA to assess fluorochemical exposure pathways and potential risks. If you have any questions, please do not hesitate to contact Dayna Blomquist at 651-736-5413. Sincerelv Katherine E. Reed Staff Vice President Environmental, Health and Safety Operations 1